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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAMAARAEAIKALVVSRKL
HRLAYIAHPKLGRRARARIARGLR

The query sequence (length=104) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8g5y:Lb 111 106 0.9615 0.9009 0.9434 2.95e-66 8b5l:b, 8b6c:b, 9bdl:AL29, 9bdn:AL29, 9bdp:AL29, 8bhf:O1, 8bpo:a2, 8btk:Bb, 7cpu:Lb, 7cpv:Lb, 6d90:b, 6d9j:b, 9f1b:Bb, 9f1c:Bb, 9f1d:Bb, 7f5s:Lb, 8g5z:Lb, 8g60:Lb, 8g61:Lb, 8g6j:Lb, 8glp:Lb, 6hcf:b3, 6hcj:b3, 6hcm:b3, 6hcq:b3, 8ifd:2V, 8ife:2V, 6ip5:2V, 6ip6:2V, 6ip8:2V, 8jdj:g, 8jdk:g, 8jdl:g, 8jdm:g, 8k2c:Lb, 5lzs:b, 5lzt:b, 5lzu:b, 5lzv:b, 5lzw:b, 5lzx:b, 5lzy:b, 5lzz:b, 7mdz:b, 6mtb:b, 6mtc:b, 6mtd:b, 6mte:b, 7nwg:b3, 7nwh:b, 7o7y:Bb, 7o7z:Bb, 7o80:Bb, 7o81:Bb, 8ohd:Lb, 8oj0:Lb, 8oj5:Lb, 8oj8:Lb, 7ow7:V, 7oyd:b, 8p2k:Bb, 6p5i:Ab, 6p5j:Ab, 6p5k:Ab, 6p5n:Ab, 6qzp:Lb, 6r5q:b, 6r6g:b, 6r7q:b, 8rjb:b, 8rjc:b, 8rjd:b, 6sgc:b2, 6t59:b3, 7tm3:b, 7toq:AL29, 7tor:AL29, 7tut:b, 7ucj:b, 7uck:b, 6xa1:Lb, 7xnx:Lb, 7xny:Lb, 8xsx:Lb, 8xsy:Lb, 8xsz:Lb, 8y0w:Lb, 8y0x:Lb, 6y6x:Lb, 8yoo:Lb, 8yop:Lb, 6z6l:Lb, 6z6m:Lb, 6z6n:Lb, 7zjw:Le, 7zjx:Le, 6zm7:Lb, 6zme:Lb, 6zmi:Lb, 6zmo:Lb
2 6ole:c 100 104 0.8750 0.9100 0.8750 2.50e-50 8a3d:V, 8fl6:LM, 8fl7:LM, 8fl9:LM, 8fla:LM, 8flb:LM, 8flc:LM, 8fld:LM, 8fle:LM, 8flf:LM, 8idt:C, 8idy:C, 8ie3:C, 8ine:C, 8inf:C, 8ink:A, 8ipd:A, 8ipx:A, 8ipy:A, 6lqm:C, 6lsr:C, 6lss:C, 6lu8:C, 6olf:c, 6oli:c, 6olz:Ab, 6om0:c, 6om7:c, 8q7z:Bb, 8q87:Bb, 7qgg:c, 8qoi:Lb, 6w6l:c
3 7ls2:V2 117 114 0.8654 0.7692 0.7895 3.22e-49 7a01:r2, 5aj0:Ab, 7bhp:Lb, 4d5y:b, 4d67:b, 6frk:b, 6ftg:b, 6fti:b, 6ftj:b, 6gz3:Ab, 6gz4:Ab, 6gz5:Ab, 3j7o:b, 3j7p:b, 3j7q:b, 3j7r:b, 3j92:b, 3jag:b, 3jah:b, 3jai:b, 3jaj:b, 3jan:b, 5lks:Lb, 7ls1:V2, 7nfx:b, 7nwi:b, 7obr:b, 6olg:Ab, 7oya:b1, 7oyb:b1, 7oyc:b1, 8qfd:b, 7qvp:Lb, 7qvp:Mb, 7qwq:b, 7qwr:b, 7qws:b, 6r6p:b, 8scb:b, 6swa:Z, 5t2c:V, 4ug0:Lb, 4ujc:Bb, 4ujd:Ab, 4uje:Cb, 4v6x:Cb, 6y0g:Lb, 6y2l:Lb, 6y57:Lb, 6zvk:r2
4 8azw:O 49 49 0.3558 0.7551 0.7551 8.97e-21 8b2l:O3, 7qiw:d, 7qiz:d
5 8ip8:OB 50 49 0.3462 0.7200 0.7347 1.91e-20 8ipa:OB, 8ipb:OB, 8jiv:Cb
6 4v7e:Cb 58 51 0.3462 0.6207 0.7059 7.77e-20
7 8oeq:BW 63 58 0.3558 0.5873 0.6379 2.14e-18 8bn3:N9, 8c3a:AC, 8c3a:BW, 8cq7:AC, 8cq7:BW, 8cqw:AC, 8cqw:BW, 8cre:AC, 8cre:BW, 5it7:bb, 5ndv:N9, 5ndw:n9, 8oeq:AC, 8p8n:RB, 8p8u:RB, 8pfr:RB, 7pzy:AC, 7q08:AC, 7q0f:AC, 7q0p:AC, 7q0r:AC, 8q5i:AC, 6qik:a, 6qt0:a, 6qtz:a, 6ri5:a, 6rzz:a, 6s05:a, 6uz7:Bb
8 8aaf:O 58 45 0.3173 0.5690 0.7333 1.16e-17 8agt:O, 8agu:O, 8agv:O, 8agw:O, 8agx:O, 8agz:O, 5apn:b, 5apo:b, 7azy:W, 7b7d:LX, 8bip:Lb, 8bjq:Lb, 8bqd:AV, 8bqx:AV, 8ccs:N, 8cdl:N, 8cdr:N, 8ceh:N, 8cf5:N, 8cg8:N, 8cgn:N, 8civ:N, 8cku:N, 8cmj:N, 5dat:N9, 5dat:n9, 5dc3:N9, 5dc3:n9, 5dge:N9, 5dge:n9, 5dgf:N9, 5dgf:n9, 5dgv:N9, 5dgv:n9, 8eub:Ab, 8evp:Ab, 8evq:Ab, 8evr:Ab, 8evs:Ab, 8evt:Ab, 8ewb:Ab, 8ewc:Ab, 5fci:N9, 5fci:n9, 5fcj:N9, 5fcj:n9, 5gak:d, 6gq1:b, 6gqb:b, 6gqv:b, 5h4p:b, 6hd7:d, 8hfr:b3, 6hhq:AC, 6hhq:DD, 5i4l:N9, 5i4l:n9, 6i7o:AV, 6i7o:XV, 3j6x:69, 3j6y:69, 3j77:79, 3j78:79, 5juo:GA, 5jup:GA, 5jus:GA, 5jut:GA, 5juu:GA, 8k2d:Lb, 8k82:Lb, 5lyb:N9, 5lyb:n9, 5m1j:b5, 5mc6:AV, 5mei:AC, 5mei:DD, 7mpi:Ab, 7mpj:Ab, 6n8j:o, 6n8k:o, 6n8l:o, 6n8m:o, 6n8n:o, 6n8o:o, 7n8b:Ab, 5ndg:N9, 5ndg:n9, 5ndv:n9, 5ndw:N9, 7nrc:Ld, 7nrd:Ld, 5obm:N9, 5obm:n9, 6oig:b, 5on6:AC, 5on6:DD, 7osa:eL29, 7osm:eL29, 8p8m:RB, 6q8y:AV, 6r84:d, 6r86:d, 6r87:d, 7rr5:Lb, 6s47:Ad, 6snt:ao, 6sv4:AV, 6sv4:XV, 6sv4:zV, 6t4q:Lb, 5t62:o, 5t6r:o, 6t7i:Lb, 6t7t:Lb, 6t83:by, 6t83:M, 5tbw:AC, 5tbw:DD, 6tb3:AV, 5tga:N9, 5tga:n9, 5tgm:N9, 5tgm:n9, 6tnu:AV, 7too:AL29, 7top:AL29, 4u3m:N9, 4u3m:n9, 4u3n:N9, 4u3n:n9, 4u3u:N9, 4u3u:n9, 4u4n:N9, 4u4n:n9, 4u4o:N9, 4u4o:n9, 4u4q:N9, 4u4q:n9, 4u4r:N9, 4u4r:n9, 4u4u:N9, 4u4u:n9, 4u4y:N9, 4u4y:n9, 4u4z:N9, 4u4z:n9, 4u50:N9, 4u50:n9, 4u51:N9, 4u51:n9, 4u52:N9, 4u52:n9, 4u53:N9, 4u53:n9, 4u55:N9, 4u55:n9, 4u56:N9, 4u56:n9, 4u6f:N9, 4u6f:n9, 4v88:Bb, 4v88:Db, 4v8t:b, 4v8y:Bb, 4v8z:Bb, 4v91:b, 6woo:b, 6xiq:b, 6xir:b, 8y0u:Lb, 7z34:o, 6z6j:Lb, 6z6k:Lb, 7zpq:Ba, 7zrs:Ba, 7zs5:Bc, 7zuw:Ba, 7zux:Ea, 7zw0:Le
9 7r81:d1 64 57 0.3462 0.5625 0.6316 4.04e-17 7olc:Lb, 7old:Lb, 8oo0:Lb, 8pv6:Lb, 8pv8:Lb, 7z3n:Lb, 7z3o:Lb
10 9bh5:Cb 52 51 0.2981 0.5962 0.6078 4.48e-17 9cai:Cb
11 3j79:4 66 45 0.2596 0.4091 0.6000 8.50e-15 3jbn:A4, 3jbo:A4, 3jbp:A4, 8tpu:A4, 5umd:4
12 4v6w:Cb 75 49 0.2981 0.4133 0.6327 1.02e-14 6xu6:Cb, 6xu7:Cb, 6xu8:Cb
13 8eui:b 56 54 0.2596 0.4821 0.5000 8.41e-13 8eug:b
14 8fru:b 57 43 0.2692 0.4912 0.6512 1.69e-12 8br8:Lc, 8brm:Lc, 8bsi:Lc, 8bsj:Lc, 8btd:Lc, 8btr:Lc, 7pwg:b, 7pwo:b2
15 4v8p:AT 65 49 0.2885 0.4615 0.6122 4.01e-12 4v8p:DT, 4v8p:FT, 4v8p:HT
16 5xxb:a 49 47 0.2885 0.6122 0.6383 4.88e-12
17 6zu5:LBB 63 52 0.2692 0.4444 0.5385 1.37e-10
18 6rm3:LBB 51 47 0.2212 0.4510 0.4894 6.59e-08
19 7qep:N9 55 47 0.2212 0.4182 0.4894 9.73e-08
20 4v8m:Bd 70 53 0.2788 0.4143 0.5472 1.60e-07 8ova:Bd, 8ove:Bd
21 5t2a:b 69 68 0.3077 0.4638 0.4706 7.75e-07 8a3w:b, 8a98:b, 6az3:b, 3jcs:b, 8ovj:b, 8rxh:Lb, 8rxx:Lb
22 5t5h:d 63 49 0.2212 0.3651 0.4694 0.002
23 5xy3:b 50 46 0.2019 0.4200 0.4565 0.003
24 6zj3:Lq 91 47 0.1923 0.2198 0.4255 0.042
25 4ku8:A 150 45 0.1442 0.1000 0.3333 0.39
26 3e78:A 365 68 0.1923 0.0548 0.2941 0.67 3e79:A, 3eki:A
27 6rm3:SFF 68 21 0.0962 0.1471 0.4762 4.8
28 4ks0:A 466 75 0.1923 0.0429 0.2667 5.3
29 7moq:C 4159 42 0.1250 0.0031 0.3095 6.9 6zyy:C
30 4fe7:A 380 69 0.1827 0.0500 0.2754 7.5
31 7lv3:A 601 44 0.1442 0.0250 0.3409 7.7 6bg2:C, 6bg2:B, 6bg2:A, 6bg2:D, 6c0t:A, 5j48:A, 5j48:B, 5jax:A, 5jd7:A, 4ku7:A, 4ku8:B, 5l0n:A, 7lv3:B, 3ocp:A, 3ocp:B, 3od0:A, 3od0:B, 3ogj:A, 3ogj:B, 3ogj:C, 3ogj:D, 4qx5:A, 4qxk:A, 3shr:A, 3shr:B, 7ssb:A, 7t4t:A, 7t4t:B, 7t4u:A, 7t4u:B, 7t4v:A, 7t4v:B, 7t4w:A, 7t4w:B, 4z07:A, 4z07:C, 4z07:E
32 6zyw:C 4433 42 0.1250 0.0029 0.3095 8.0
33 8bwy:C 4264 42 0.1250 0.0030 0.3095 8.0
34 8bx8:A 4453 42 0.1250 0.0029 0.3095 8.0 7k58:A, 7k5b:A, 7kek:A
35 7l7b:D 1148 20 0.0865 0.0078 0.4500 8.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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