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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLAT
VMNGLAMRDALHRAYVNARLMSAIPLNVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEANVVLKAT
KVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE

The query sequence (length=236) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2bne:B 238 237 0.9958 0.9874 0.9916 8.18e-171 2bnd:A, 2bnd:B, 2bne:A, 2bnf:A, 2bnf:B, 2v4y:A, 2v4y:E, 2v4y:F, 2v4y:B, 2v4y:D, 2v4y:C
2 3ek5:A 241 231 0.5593 0.5477 0.5714 7.96e-91 3ek5:B, 3ek5:C, 3ek5:F, 3ek5:E, 3ek5:D
3 2jjx:A 244 235 0.4322 0.4180 0.4340 1.52e-64 2jjx:B, 2jjx:C
4 4a7x:C 234 226 0.4873 0.4915 0.5088 4.71e-63 4a7w:A, 4a7w:B, 4a7x:B, 4a7x:D, 4a7x:E
5 3nwy:B 231 232 0.4492 0.4589 0.4569 4.00e-61 7bes:A, 7bes:B, 7bes:C, 7bix:A, 7bix:C, 7bix:B, 7bix:E, 7bix:D, 7bix:G, 7bix:I, 7bix:H, 7bix:K, 7bix:J, 7bl7:B, 7bl7:A, 7bl7:C, 7bl7:F, 7bl7:D, 7bl7:E, 7bl7:I, 7bl7:K, 7bl7:J, 7bl7:H, 7bl7:L, 7bl7:G, 3nwy:A, 3nwy:D, 3nwy:C, 3nwy:E, 3nwy:F
6 2va1:B 235 233 0.3559 0.3574 0.3605 2.36e-45 2va1:A, 2va1:C, 2va1:D, 2va1:E, 2va1:F
7 2bmu:B 226 203 0.2712 0.2832 0.3153 3.27e-12 2bmu:A, 2bri:A, 2bri:B, 2ji5:A, 2ji5:B
8 2j4k:C 206 230 0.2585 0.2961 0.2652 2.23e-06 2j4l:H
9 5yei:C 397 242 0.2627 0.1562 0.2562 5.28e-06 5yei:D, 5yei:B, 5yei:A, 5yei:F, 5yei:E, 5yei:H, 5yei:G
10 3c1m:C 468 99 0.1441 0.0726 0.3434 7.18e-06 3c1m:A, 3c1m:B, 3c1m:D, 3c1n:A, 3c1n:B, 3c1n:C, 3c1n:D, 3c20:A, 3c20:B, 2hmf:A, 2hmf:B, 2hmf:C, 2hmf:D
11 2j4j:F 226 240 0.2754 0.2876 0.2708 3.15e-05 2j4j:A, 2j4j:E, 2j4j:B, 2j4j:D, 2j4j:C, 2j4k:A, 2j4k:B, 2j4k:D, 2j4k:E, 2j4k:F, 2j4l:A, 2j4l:B, 2j4l:C, 2j4l:D, 2j4l:E, 2j4l:F, 2j4l:G, 2j4l:I, 2j4l:J, 2j4l:K, 2j4l:L
12 3ab4:A 370 67 0.1102 0.0703 0.3881 5.45e-05 3ab4:C, 3ab4:E, 3ab4:G, 3ab4:I, 3ab4:O
13 3aaw:C 392 67 0.1102 0.0663 0.3881 5.50e-05 3aaw:A, 3aaw:B, 3aaw:D, 3ab2:A, 3ab2:B, 3ab2:C, 3ab2:D, 3ab2:E, 3ab2:F, 3ab2:G, 3ab2:H, 3ab2:I, 3ab2:J, 3ab2:K, 3ab2:L, 3ab2:M, 3ab2:N, 3ab2:O, 3ab2:P, 3ab4:B, 3ab4:D, 3ab4:F, 3ab4:H, 3ab4:J, 3ab4:K, 3ab4:L, 3ab4:M, 3ab4:N, 3ab4:P, 2dtj:A, 2dtj:B
14 7wx3:B 258 101 0.1059 0.0969 0.2475 1.75e-04 7wx3:A, 7wx3:C, 7wx3:D, 7wx4:A
15 6yt3:B 376 143 0.1610 0.1011 0.2657 1.90e-04 4f6t:B, 6gu5:B, 6guj:B, 6gx4:B, 6h6w:B, 6h73:B, 6h74:B, 6h8b:B, 6h8h:B, 4ndo:B, 4ndp:B, 4ndq:B, 4ndr:B, 5o5w:B, 6ris:B, 6rj4:B, 6rj4:D, 6rj4:F, 6rkd:B, 6rkd:F, 6rkd:D, 6rkd:H, 6rkd:J, 6rkd:L, 6rke:B, 6rke:D, 6rke:F, 6rke:H, 6rke:J, 6rke:L, 7z5j:B, 7z5j:D, 7z5j:F, 7z5j:H, 7z5j:J, 7z5j:L, 7zqq:B, 7zr4:B, 7zse:B
16 7f5x:A 236 96 0.1017 0.1017 0.2500 0.003 7f5x:B, 7f5x:C, 7f5x:D
17 2cdq:A 470 78 0.1102 0.0553 0.3333 0.044 2cdq:B
18 3ll9:B 249 81 0.0975 0.0924 0.2840 0.084 3ll9:A
19 1l9y:A 263 46 0.0720 0.0646 0.3696 0.35 1jt1:A, 1k07:A, 1k07:B, 1l9y:B, 5w90:A, 5wck:A, 5wck:B
20 3k4y:A 260 112 0.1271 0.1154 0.2679 0.52 3k4y:B, 3k52:A, 3k52:B, 3k56:A, 3k56:B
21 5mfa:A 588 57 0.0678 0.0272 0.2807 0.75 6azp:A, 6bmt:A, 4c1m:D, 4c1m:C, 4c1m:A, 4c1m:B, 1cxp:D, 1cxp:C, 1cxp:A, 1cxp:B, 1d2v:D, 1d2v:C, 1d2v:A, 1d2v:B, 1d5l:D, 1d5l:C, 1d5l:A, 1d5l:B, 1d7w:D, 1d7w:C, 1d7w:A, 1d7w:B, 4dl1:D, 4dl1:C, 4dl1:H, 4dl1:G, 4dl1:L, 4dl1:K, 4dl1:P, 4dl1:O, 4dl1:A, 4dl1:B, 4dl1:E, 4dl1:F, 4dl1:I, 4dl1:J, 4dl1:M, 4dl1:N, 1dnu:D, 1dnu:C, 1dnu:A, 1dnu:B, 1dnw:D, 1dnw:C, 1dnw:A, 1dnw:B, 4ejx:B, 4ejx:D, 3f9p:C, 3f9p:D, 3f9p:A, 3f9p:B, 5fiw:A, 5fiw:C, 5fiw:B, 5fiw:D, 7lae:A, 7lae:B, 7lae:E, 7lae:D, 7lag:E, 7lag:B, 7lag:I, 7lag:G, 7lag:A, 7lag:D, 7lag:F, 7lag:H, 7lal:B, 7lal:A, 7lal:E, 7lal:D, 7lan:E, 7lan:B, 7lan:I, 7lan:G, 7lan:A, 7lan:D, 7lan:F, 7lan:H, 1mhl:D, 1mhl:C, 1mhl:A, 1mhl:B, 1myp:C, 1myp:A, 1myp:D, 1myp:B, 7ni1:A, 7ni1:C, 7ni1:B, 7ni1:D, 7ni3:A, 7ni3:C, 7ni3:B, 7ni3:D, 7oih:H, 7oih:G, 7oih:B, 7oih:A, 7oih:D, 7oih:C, 7oih:F, 7oih:E, 5qj2:B, 5qj2:A, 5qj2:E, 5qj2:D, 5qj2:G, 5qj2:F, 5qj2:I, 5qj2:H, 5qj3:B, 5qj3:A, 5qj3:D, 5qj3:E, 7qzr:D, 7qzr:B, 7qzr:A, 7qzr:C, 5uzu:A, 5wdj:B, 5wdj:A, 5wdj:D, 5wdj:E, 6wxz:B, 6wxz:E, 6wxz:A, 6wxz:D, 6wy0:E, 6wy0:B, 6wy0:I, 6wy0:G, 6wy0:A, 6wy0:D, 6wy0:F, 6wy0:H, 6wy5:E, 6wy5:B, 6wy5:A, 6wy5:D, 6wy7:E, 6wy7:B, 6wy7:A, 6wy7:D, 6wyd:A, 6wyd:B, 6wyd:E, 6wyd:D, 6wyd:G, 6wyd:F, 6wyd:H, 6wyd:I, 7z53:D, 7z53:B, 7z53:J, 7z53:H, 7z53:P, 7z53:N, 7z53:V, 7z53:T, 7z53:A, 7z53:C, 7z53:G, 7z53:I, 7z53:M, 7z53:O, 7z53:S, 7z53:U, 3zs0:D, 3zs0:C, 3zs0:A, 3zs0:B, 3zs1:A, 3zs1:C, 3zs1:B, 3zs1:D
22 6rke:A 272 231 0.2585 0.2243 0.2641 1.1 4f6t:A, 6gu5:A, 6guj:A, 6gwb:A, 6gwv:A, 6gwv:P, 6gx4:A, 6h6w:A, 6h73:A, 6h74:A, 6h8b:A, 6h8h:A, 4ndo:A, 4ndp:A, 4ndq:A, 4ndr:A, 5o5w:A, 2ogx:A, 6ris:A, 6rj4:A, 6rj4:C, 6rj4:E, 6rkd:A, 6rkd:C, 6rkd:E, 6rkd:G, 6rkd:I, 6rkd:K, 6rke:C, 6rke:E, 6rke:G, 6rke:I, 6rke:K, 6yt3:A, 7z5j:A, 7z5j:C, 7z5j:E, 7z5j:I, 7z5j:G, 7z5j:K, 7zqq:A, 7zr4:A, 7zse:A
23 3tvi:E 439 71 0.0805 0.0433 0.2676 2.7 3tvi:A, 3tvi:B, 3tvi:C, 3tvi:D, 3tvi:G, 3tvi:H, 3tvi:I, 3tvi:L
24 3lkk:B 238 32 0.0381 0.0378 0.2812 5.2 3lkk:A, 3ll5:A, 3ll5:B, 3ll5:C, 3ll5:D
25 8hh1:D 471 133 0.1525 0.0764 0.2707 5.9 8hh1:E, 8hh1:F, 8hh2:D, 8hh2:E, 8hh2:F, 8hh3:D, 8hh3:E, 8hh3:F, 8hh4:D, 8hh4:E, 8hh4:F, 8hh5:D, 8hh5:E, 8hh5:F, 8hh6:D, 8hh6:E, 8hh6:F, 8hh7:D, 8hh7:F, 8hh8:D, 8hh8:F, 8hh9:D, 8hh9:F, 8hha:D, 8hha:F, 8hhb:D, 8hhb:F, 8hhc:D, 8hhc:F, 7l1q:D, 7l1q:E, 7l1q:F, 7l1r:D, 7l1r:E, 7l1r:F, 7l1s:D, 7l1s:F, 6n2y:E, 6n2y:F, 6n2z:F, 6n2z:D, 6n30:D, 6n30:E, 8spw:D, 8spw:E, 8spx:D, 8spx:E, 8spx:F, 8u1h:D, 8u1h:F, 4xd7:F, 7xkp:F, 7xkq:D, 7xkq:E, 7xkq:F, 7xkr:D, 7xkr:E, 7xkr:F
26 6xiw:A 1256 85 0.1102 0.0207 0.3059 6.4
27 7cu3:A 1277 85 0.1102 0.0204 0.3059 6.4
28 7sx3:A 1386 85 0.1102 0.0188 0.3059 6.4 7sx4:A
29 2pv7:B 280 29 0.0551 0.0464 0.4483 7.0 2pv7:A
30 8uzh:B 626 70 0.0720 0.0272 0.2429 9.1 4lxf:A, 8uqv:A, 8uqv:B, 8uqv:C, 8uqv:D, 8uzh:A
31 4lxf:B 546 70 0.0720 0.0311 0.2429 9.2
32 3syb:A 408 37 0.0593 0.0343 0.3784 9.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218