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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AKPGFTDYIVKDIALADFGRKEISLAETEMPGLMATREEYGPKQPLKGARIAGSLHMTIQTAVLIETLAALGADIRWVSC
NIYSTQDHAAAAIAAAGIPVFAVKGETLTEYWDYTAKLFDWHGGGTPNMILDDGGDATMLVHAGYRAEQGDTAFLDKPGS
EEEEIFYALVKRLLKEKPKGWFAEIAKNIKGVSEETTTGVHRLYEMANKGTLLFPAINVNDSVTKSKFDNLYGCRESLVD
GIRRGTDVMLSGKVAMVAGFGDVGKGSAASLRQAGCRVMVSEVDPICALQAAMEGYEVVTMEDAAPRADIFVTATGNKDI
ITIEHMRAMKDRAIVCNIGHFDNEIQIASLRNLKWTNIKPQVDEIEFPDKHRIIMLSEGRLVNLGNAMGHPSFVMSASFT
NQTLAQIELFANNKDSKYAKKVYVLPKTLDEKVARLHLAKIGVKLTELRKDQADYIGVKQEGPYKSDHYRY

The query sequence (length=471) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5m5k:C 471 471 1.0000 1.0000 1.0000 0.0 6exi:A, 6exi:B, 6exi:C, 6exi:D, 4lvc:A, 4lvc:B, 4lvc:C, 4lvc:D, 5m5k:A, 5m5k:B, 5m5k:D, 5m65:A, 5m65:B, 5m66:A, 5m66:B, 5m66:C, 5m66:D, 5m67:A, 5m67:B, 5m67:C, 5m67:D
2 3n58:B 461 463 0.7006 0.7158 0.7127 0.0 3n58:A, 3n58:C, 3n58:D
3 3d64:A 462 465 0.6667 0.6797 0.6753 0.0 3d64:B, 3glq:A, 3glq:B
4 6uk3:A 475 467 0.6603 0.6547 0.6660 0.0 6uk3:C, 6uk3:B, 6uk3:D
5 5v96:A 467 468 0.6348 0.6403 0.6389 0.0 5v96:B, 5v96:C, 5v96:D
6 3ond:B 488 474 0.6412 0.6189 0.6371 0.0 3ond:A, 3one:A, 3one:B, 3onf:A, 3onf:B
7 3ce6:A 486 481 0.6072 0.5885 0.5946 0.0 3ce6:B, 3ce6:C, 3ce6:D, 3dhy:A, 3dhy:B, 3dhy:C, 3dhy:D, 2ziz:A, 2ziz:B, 2ziz:C, 2ziz:D, 2zj0:A, 2zj0:B, 2zj0:C, 2zj0:D, 2zj1:A, 2zj1:B, 2zj1:C, 2zj1:D
8 6gbn:B 435 471 0.6115 0.6621 0.6115 0.0 6gbn:A, 6gbn:C, 6gbn:D
9 3h9u:C 435 471 0.5945 0.6437 0.5945 0.0 3h9u:A, 3h9u:B, 3h9u:D
10 1v8b:A 476 473 0.5435 0.5378 0.5412 0.0 1v8b:B, 1v8b:C, 1v8b:D
11 6aph:A 432 471 0.6115 0.6667 0.6115 0.0
12 1a7a:A 431 467 0.5690 0.6218 0.5739 4.23e-175 1a7a:B, 5axa:A, 5axa:C, 5axb:A, 5axb:C, 5axc:A, 5axc:C, 5axd:A, 5axd:C, 1b3r:A, 1b3r:B, 1b3r:C, 1b3r:D, 8cod:A, 8cod:B, 1d4f:A, 1d4f:B, 1d4f:C, 1d4f:D, 2h5l:A, 2h5l:B, 2h5l:C, 2h5l:D, 2h5l:E, 2h5l:F, 2h5l:G, 2h5l:H, 1k0u:A, 1k0u:B, 1k0u:C, 1k0u:D, 1k0u:E, 1k0u:F, 1k0u:G, 1k0u:H, 1ky4:A, 1ky4:B, 1ky4:C, 1ky4:D, 1ky5:A, 1ky5:B, 1ky5:C, 1ky5:D, 1li4:A, 3nj4:A, 3nj4:B, 3nj4:C, 3nj4:D, 4pfj:A, 4pfj:B, 4pgf:A, 4pgf:B, 5w49:A, 5w49:B, 5w4b:A, 5w4b:B, 5w4b:C, 5w4b:D, 5w4b:E, 5w4b:F, 1xwf:A, 1xwf:B, 1xwf:C, 1xwf:D, 4yvf:A, 4yvf:B
13 3g1u:C 424 466 0.5732 0.6368 0.5794 6.88e-174 3g1u:A, 3g1u:B, 3g1u:D
14 5jpi:A 496 490 0.5308 0.5040 0.5102 1.53e-164 5hm8:A, 5hm8:B, 5hm8:C, 5hm8:D, 5hm8:E, 5hm8:F, 5hm8:G, 5hm8:H, 5jpi:B, 5jpi:C, 5jpi:D, 5jxw:A, 5jxw:B, 5jxw:C, 5jxw:D, 5t8k:A, 5t8k:C, 5t8k:B, 5t8k:D, 5tj9:A, 5tj9:B, 5tj9:C, 5tj9:D, 5tls:A, 5tls:B, 5tls:C, 5tls:D, 5utu:A, 5utu:B, 5utu:C, 5utu:D, 5utu:E, 5utu:F, 5utu:G, 5utu:H
15 8cfu:A 467 498 0.5478 0.5525 0.5181 2.77e-153 8ajs:AAA, 8ajs:DDD, 8ajs:BBB, 8ajs:CCC, 8ajt:AAA, 8ajt:DDD, 8ajt:BBB, 8ajt:CCC, 8aju:AAA, 8aju:CCC, 8ajv:AAA, 8ajv:DDD, 8ajv:BBB, 8ajv:CCC, 8ajv:FFF, 8ajv:III, 8ajv:GGG, 8ajv:HHH, 8ajw:AAA, 8ajw:DDD, 8ajw:BBB, 8ajw:CCC, 8azf:A, 8azf:C, 8cfb:A, 8cfb:D, 8cfb:B, 8cfb:C, 8cfc:A, 8cfc:D, 8cfc:B, 8cfc:C, 8cfd:A, 8cfd:D, 8cfd:B, 8cfd:C, 8cfe:A, 8cfe:D, 8cfe:B, 8cfe:C, 8cfg:A, 8cfg:D, 8cfg:B, 8cfg:C, 8cfh:A, 8cfh:D, 8cfh:B, 8cfh:C, 8cfi:A, 8cfi:D, 8cfi:B, 8cfi:C, 8cfj:A, 8cfj:D, 8cfj:B, 8cfj:C, 8cfk:A, 8cfk:D, 8cfk:B, 8cfk:C, 8cfl:A, 8cfl:D, 8cfl:B, 8cfl:C, 8cfm:A, 8cfm:D, 8cfm:B, 8cfm:C, 8cfn:A, 8cfn:C, 8cfo:A, 8cfo:D, 8cfo:B, 8cfo:C, 8cfp:A, 8cfp:D, 8cfp:B, 8cfp:C, 8cfq:A, 8cfq:D, 8cfq:B, 8cfq:C, 8cfr:A, 8cfr:D, 8cfr:B, 8cfr:C, 8cfs:A, 8cfs:D, 8cfs:B, 8cfs:C, 8cft:A, 8cft:D, 8cft:B, 8cft:C, 8cfu:D, 8cfu:B, 8cfu:C, 8cfv:A, 8cfv:D, 8cfv:B, 8cfv:C, 8cfw:A, 8cfw:D, 8cfw:B, 8cfw:C, 8cfx:A, 8cfx:D, 8cfx:B, 8cfx:C, 8cfx:G, 8cfx:J, 8cfx:H, 8cfx:I, 8cfy:A, 8cfy:D, 8cfy:B, 8cfy:C, 8cfy:G, 8cfy:J, 8cfy:H, 8cfy:I, 8cfz:A, 8cfz:D, 8cfz:B, 8cfz:C, 8cfz:H, 8cfz:K, 8cfz:I, 8cfz:J, 8cg0:A, 8cg0:D, 8cg0:B, 8cg0:C, 8cg1:A, 8cg1:D, 8cg1:B, 8cg1:C, 8cg1:G, 8cg1:J, 8cg1:H, 8cg1:I, 8cg2:A, 8cg2:C, 6f3m:A, 6f3m:B, 6f3m:C, 6f3m:D, 6f3n:A, 6f3n:B, 6f3n:C, 6f3n:D, 6f3o:A, 6f3o:B, 6f3o:C, 6f3o:D, 6f3p:A, 6f3p:C, 6f3q:A, 6f3q:B, 6f3q:C, 6f3q:D, 7zd0:A, 7zd0:D, 7zd0:B, 7zd0:C, 7zd1:A, 7zd1:D, 7zd1:B, 7zd1:C, 7zd2:A, 7zd2:D, 7zd2:B, 7zd2:C, 7zd3:A, 7zd3:D, 7zd3:B, 7zd3:C, 7zd4:A, 7zd4:D, 7zd4:B, 7zd4:C
16 3gvp:A 433 469 0.4650 0.5058 0.4670 1.20e-148 3gvp:B, 3gvp:C, 3gvp:D, 3mtg:A, 3mtg:B
17 7r39:A 412 449 0.3822 0.4369 0.4009 2.20e-103 7r39:B, 7r39:C, 7r39:D, 7r39:E, 7r39:F, 7r39:G, 7r39:H
18 8qno:A 421 458 0.3970 0.4442 0.4083 5.49e-103 8qno:B, 7r37:A, 7r37:B, 7r38:A, 7r38:B
19 7r3a:A 411 449 0.3694 0.4234 0.3875 3.25e-93 7r3a:B, 7r3a:C, 7r3a:D, 7r3a:E, 7r3a:F, 7r3a:G, 7r3a:H
20 7o5l:A 417 452 0.3715 0.4197 0.3872 3.60e-90 7o5l:C, 7o5m:A, 7o5m:C, 7zd7:A, 7zd7:C, 7zd8:A, 7zd8:C, 7zd9:A, 7zd9:C
21 3x2f:A 406 440 0.3418 0.3966 0.3659 6.42e-85 5tov:B, 5tow:B, 3x2e:A, 3x2e:B, 3x2e:C, 3x2e:D, 3x2f:B
22 6jcz:C 331 148 0.0828 0.1178 0.2635 0.002 6jcw:A, 6jcw:B, 6jcw:C, 6jcw:D, 6jcw:E, 6jcw:F, 6jcw:G, 6jcw:H, 6jcw:I, 6jcw:J, 6jcw:K, 6jcw:L, 6jcz:A, 6jcz:B, 6jcz:D, 6jcz:E, 6jcz:F, 6jcz:G, 6jcz:H, 6jcz:I, 6jcz:J, 6jcz:K, 6jcz:L, 6jd1:A, 6jd1:B, 6jd1:C, 6jd1:D, 6jd1:E, 6jd1:F, 6jd1:G, 6jd1:H, 6jd1:I, 6jd1:J, 6jd1:K, 6jd1:L, 6jd2:A, 6jd2:B, 6jd2:C, 6jd2:D, 6jd2:E, 6jd2:F, 6jd2:G, 6jd2:H, 6jd2:I, 6jd2:J, 6jd2:K, 6jd2:L, 6kou:A, 6kou:B, 6kou:C, 6kou:D, 6kou:E, 6kou:F, 6kou:G, 6kou:H, 6kou:I, 6kou:J, 6kou:K, 6kou:L, 6kpa:A, 6kpa:B, 6kpa:C, 6kpa:D, 6kpa:E, 6kpa:F, 6kpa:G, 6kpa:H, 6kpa:I, 6kpa:J, 6kpa:K, 6kpa:L, 6kph:A, 6kph:B, 6kph:C, 6kph:D, 6kph:E, 6kph:F, 6kph:G, 6kph:H, 6kph:I, 6kph:J, 6kph:K, 6kph:L, 6kpi:A, 6kpi:B, 6kpi:C, 6kpi:D, 6kpi:E, 6kpi:F, 6kpi:G, 6kpi:H, 6kpi:I, 6kpi:J, 6kpi:K, 6kpi:L, 6kpj:A, 6kpj:B, 6kpj:C, 6kpj:D, 6kpj:E, 6kpj:F, 6kpj:G, 6kpj:H, 6kpj:I, 6kpj:J, 6kpj:K, 6kpj:L, 6kq4:A, 6kq4:B, 6kq4:C, 6kq4:D, 6kq4:E, 6kq4:F, 6kq4:G, 6kq4:H, 6kq4:I, 6kq4:J, 6kq4:K, 6kq4:L, 6kqj:A, 6kqj:B, 6kqj:C, 6kqj:D, 6kqj:E, 6kqj:F, 6kqj:G, 6kqj:H, 6kqj:I, 6kqj:J, 6kqj:K, 6kqj:L, 6kqk:A, 6kqk:B, 6kqk:C, 6kqk:D, 6kqk:E, 6kqk:F, 6kqk:G, 6kqk:H, 6kqk:I, 6kqk:J, 6kqk:K, 6kqk:L, 6kqo:A, 6kqo:B, 6kqo:C, 6kqo:D, 6kqo:E, 6kqo:F, 6kqo:G, 6kqo:H, 6kqo:I, 6kqo:J, 6kqo:K, 6kqo:L
23 7pci:A 345 100 0.0573 0.0783 0.2700 0.003 7pcc:A, 7pcc:B, 7pce:A, 7pcg:A, 7pcg:B, 7pcl:A, 7pcl:B, 7pcm:A, 7pcm:B, 7pcn:A, 7pcn:B, 7pco:A, 7pco:B, 7pct:A, 7pct:B
24 8ep7:C 328 63 0.0446 0.0640 0.3333 0.076 8ep7:A, 8ep7:B
25 8upq:B 342 82 0.0510 0.0702 0.2927 0.084 8cy8:A, 8cy8:B, 8cy8:C, 8cy8:D, 8cy8:E, 8cy8:F, 8cy8:G, 8cy8:H, 8cy8:I, 8cy8:J, 8cy8:K, 8cy8:L, 7lat:A, 7rdu:A, 8swm:A, 8sxd:A, 8upn:A, 8upp:B, 8upp:A, 8upp:H, 8upp:K, 8upp:I, 8upp:J, 8upp:D, 8upp:E, 8upp:G, 8upp:F, 8upp:L, 8upp:C, 8upq:A, 8upq:C, 8upq:D, 8upq:F, 8upq:E
26 7q03:A 328 61 0.0425 0.0610 0.3279 0.12 7q07:A
27 6jx2:B 327 65 0.0382 0.0550 0.2769 0.83 6jx2:A, 6jx2:C, 6jx2:D
28 1lss:A 132 75 0.0467 0.1667 0.2933 0.96 1lss:B, 1lss:C, 1lss:D
29 1vl8:B 252 62 0.0488 0.0913 0.3710 1.3 1vl8:A
30 1bw9:A 350 83 0.0616 0.0829 0.3494 1.5 1bw9:B, 1bxg:A, 1bxg:B, 1c1d:A, 1c1d:B, 1c1x:A, 1c1x:B
31 4q9n:A 295 40 0.0361 0.0576 0.4250 1.8 4q9n:B, 4q9n:C, 4q9n:D, 4q9n:E, 4q9n:F, 4q9n:G, 4q9n:H
32 3qbo:B 359 57 0.0425 0.0557 0.3509 2.2 3qbo:A
33 2yjz:A 174 62 0.0403 0.1092 0.3065 2.3 2yjz:B, 2yjz:C, 2yjz:D
34 4efz:A 295 83 0.0552 0.0881 0.3133 2.6 4efz:B
35 6bii:A 332 100 0.0531 0.0753 0.2500 3.1 6bii:B
36 6bul:B 327 65 0.0403 0.0581 0.2923 3.3 6aqj:A, 6aqj:B, 6bul:A, 6c55:A, 6c55:B, 6c5n:A, 6c5n:B, 7ke2:B, 7ke2:A, 7kh7:A, 7kh7:B, 6vo2:A, 6vo2:B, 5w3k:A, 5w3k:B
37 6l2i:A 324 64 0.0446 0.0648 0.3281 3.6 6l2i:B, 6l2z:A, 6l2z:B
38 8val:E 337 40 0.0318 0.0445 0.3750 4.4 1a5t:A, 8giy:E, 8giz:E, 8gj0:E, 8gj1:E, 8gj2:E, 8gj3:E, 3glf:E, 3glf:J, 3glg:E, 3glg:J, 3gli:E, 3gli:J, 1jr3:E, 8vam:E, 8vap:E, 8vaq:E, 8var:E, 8vas:E, 8vat:E, 1xxh:E, 1xxh:J, 1xxi:E, 1xxi:J
39 2fws:A 139 82 0.0467 0.1583 0.2683 4.6
40 3fg3:A 687 59 0.0403 0.0277 0.3220 5.8 3fg1:A, 3fg1:B, 3fg1:C, 3fg1:D, 3fg3:B, 3fg3:C, 3fg3:D, 3fg4:A, 3fg4:B, 3fg4:C, 3fg4:D, 2fnq:A, 2fnq:B, 4qwt:A, 4qwt:B, 4qwt:C, 4qwt:D
41 4za2:D 247 38 0.0361 0.0688 0.4474 6.1
42 2ekl:A 312 92 0.0510 0.0769 0.2609 8.0
43 8a22:Xb 244 77 0.0446 0.0861 0.2727 8.1 8apn:Xb, 8apo:Xb
44 3gz6:A 219 67 0.0425 0.0913 0.2985 8.4 3gz6:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218