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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AKHATPLLDQLQSGPWPSFVADIKEEAERRHSNQDNVEYQIPVDVCDDLLGILELKYSDGTTHWKHGGIVGVFGYGGGVI
GRYCDQPQMFPGVAHFHTVRVAQPAGMYYTTDFLKQLCDLWDMRGSGLTNMHGATGDIVLLGTTTPQLEEFYFELTHKMN
NDLGGSGSNLRTPASCLGDSRCEWACYDAQELCYQMTQEYQDELHRPAFPYKFKFKFDGCPNGCVASIARSDMSFIGTWR
DDIRIDQEAVAAYVGGEIQPNGGAHSGKDWGAFDIQKEVIDLCPTECMWMEDGKLQINNRECTRCMHCLNVMPRALRIGN
DRGLSILVGAKAPILDGAQMGSLLVPFIKVEDPYDEIKEIIEGIWEWWMEEGKNRERLGELIKRQGLAKAIAAVGLTPVP
QHVMEPRHNPYIFWKEKDVEGGWDRDIADYRKHHQR

The query sequence (length=436) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2xsj:A 436 436 1.0000 1.0000 1.0000 0.0 2xsj:D
2 3or1:A 435 435 0.7294 0.7310 0.7310 0.0 3or1:D, 3or2:A, 3or2:D
3 2v4j:A 436 436 0.7317 0.7317 0.7317 0.0 2v4j:D
4 3mm5:A 417 418 0.4954 0.5180 0.5167 1.27e-142 3mm5:D, 3mm6:A, 3mm6:D, 3mm7:A, 3mm7:D, 3mm8:A, 3mm8:D, 3mm9:A, 3mm9:D, 3mma:A, 3mma:D, 3mmb:A, 3mmb:D, 3mmc:A, 3mmc:D
5 7np8:B 620 302 0.1628 0.1145 0.2351 2.75e-10 7np8:A, 7np8:C, 7np8:D
6 7npa:A 618 312 0.1697 0.1197 0.2372 1.38e-09 7npa:B, 7npa:C, 7npa:D, 7npa:E, 7npa:F, 7npa:G, 7npa:H, 7npa:I, 7npa:J, 7npa:K, 7npa:L, 7npa:M, 7npa:N, 7npa:O, 7npa:P
7 3or1:B 385 268 0.1376 0.1558 0.2239 1.08e-08 3or1:E, 3or2:B, 3or2:E
8 2v4j:B 380 342 0.1674 0.1921 0.2135 1.54e-08 2v4j:E
9 3mm5:B 363 344 0.1560 0.1873 0.1977 1.60e-07 3mm5:E, 3mm6:B, 3mm6:E, 3mm7:B, 3mm7:E, 3mm8:B, 3mm8:E, 3mm9:B, 3mm9:E, 3mma:B, 3mma:E, 3mmb:B, 3mmb:E, 3mmc:B, 3mmc:E
10 7lnu:B 261 34 0.0321 0.0536 0.4118 0.13 7lnt:B, 7lnw:A, 7lnw:B, 7lnx:B, 7n9d:A, 7n9d:B
11 7lnu:A 239 34 0.0321 0.0586 0.4118 0.14 7lnt:A, 7lnx:A
12 1f8f:A 362 108 0.0711 0.0856 0.2870 0.15
13 3hkz:D 264 44 0.0321 0.0530 0.3182 1.00 4ayb:D, 3hkz:O, 2pa8:D, 2pmz:D, 2pmz:S, 4v8s:AS, 4v8s:BD, 2waq:D, 2wb1:D, 2wb1:S, 2y0s:D, 2y0s:S
14 2v2k:A 104 37 0.0298 0.1250 0.3514 5.7 2v2k:B
15 8fnv:A 770 59 0.0413 0.0234 0.3051 6.5 8fnv:B, 8fnv:C, 8fnv:D, 8fnv:E, 8fnv:F, 8fnv:G, 8fnv:H, 8fnv:I, 8fnv:J, 8fnv:K, 8fnv:L, 8fnw:A, 8fnw:B, 8fnw:C, 8fnw:D, 8fnw:E, 8fnw:F, 8fnw:G, 8fnw:H, 8fnw:I, 8fnw:J, 8fnw:K, 8fnw:L
16 2zvs:A 81 24 0.0229 0.1235 0.4167 6.7 2zvs:B, 2zvs:C
17 1h98:A 77 37 0.0229 0.1299 0.2703 6.9
18 4a3q:A 356 35 0.0298 0.0365 0.3714 9.4 4a3q:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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