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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AKFEDKVDLYDDRGNLVEEQVPLEALSPLRNPAIKSIVQGIKRTVAVNLEGIENALKTAKVGGPACKIMGRELDLDIVGN
AESIAAAAKEMIQVTEDDDTNVELLGGGKRALVQVPSARFDVAAEYSAAPLVTATAFVQAIINEFDVSMYDANMVKAAVL
GRYPQSVEYMGANIATMLDIPQKLEGPGYALRNIMVNHVVAATLKNTLQAAALSTILEQTAMFEMGDAVGAFERMHLLGL
AYQGMNADNLVFDLVKANGKEGTVGSVIADLVERALEDGVIKVEKELTDYKVYGTDDLAMWNAYAAAGLMAATMVNQGAA
RAAQGVSSTLLYYNDLIEFETGLPSVDFGKVEGTAVGFSFFSHSIYGGGGPGIFNGNHIVTRHSKGFAIPCVAAAMALDA
GTQMFSPEATSGLIKEVFSQVDEFREPLKYVVEAAAEIKNEI

The query sequence (length=442) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5a0y:E 442 442 1.0000 1.0000 1.0000 0.0 5a0y:B, 5a8k:B, 5a8k:E, 7b2h:B, 7b2h:E, 5g0r:E, 5g0r:B, 1hbm:B, 1hbm:E, 1hbn:B, 1hbn:E, 1hbo:B, 1hbo:E, 1hbu:B, 1hbu:E, 3m1v:E, 3m1v:B, 3m2r:E, 3m2r:B, 3m2u:E, 3m2u:B, 3m2v:E, 3m2v:B, 3m30:E, 3m30:B, 3m32:B, 3m32:E, 1mro:E, 1mro:B, 3pot:E, 3pot:B, 7suc:b, 7suc:B, 7sxm:E, 7sxm:B
2 5a8r:B 442 441 0.6697 0.6697 0.6712 0.0 5a8r:E, 5a8r:H, 5a8r:K, 5a8w:B, 5a8w:E, 5a8w:H, 5a8w:K
3 1e6v:E 436 433 0.6900 0.6995 0.7044 0.0 1e6v:B
4 5n28:B 443 442 0.6765 0.6749 0.6765 0.0 5n28:E, 5n2a:B
5 5n1q:B 442 442 0.6493 0.6493 0.6493 0.0 5n1q:E
6 7nkg:B 432 428 0.5995 0.6134 0.6192 7.76e-180 7nkg:E, 7nkg:H, 7nkg:K
7 1e6y:E 433 429 0.5679 0.5797 0.5851 1.30e-177 1e6y:B
8 8gf5:C 429 428 0.5724 0.5897 0.5911 9.26e-175
9 7b1s:B 466 453 0.4977 0.4721 0.4857 5.84e-144 7b1s:E, 7b2c:B, 7b2c:E
10 3sqg:B 431 432 0.4774 0.4896 0.4884 5.89e-127 3sqg:E, 3sqg:H
11 3n6s:A 344 64 0.0362 0.0465 0.2500 1.5 5cky:O, 5co0:O, 5crj:O, 5crk:O, 3mva:O, 3mvb:O, 3n7q:A
12 4h60:A 120 54 0.0407 0.1500 0.3333 1.9
13 7yp3:F 419 37 0.0317 0.0334 0.3784 3.8 7yp3:B, 7yp3:C, 7yp3:D, 7yp3:E, 7yp5:A, 7yp5:B, 7yp6:A, 7yp6:B
14 1k8c:B 319 63 0.0452 0.0627 0.3175 7.1 1k8c:A, 1k8c:C, 1k8c:D, 1mi3:A, 1mi3:B, 1mi3:C, 1mi3:D, 1r38:A, 1r38:B, 1r38:C, 1r38:D, 1sm9:A, 1sm9:B, 1sm9:C, 1sm9:D, 1ye4:A, 1ye4:B, 1ye4:C, 1ye4:D, 1ye6:A, 1ye6:B, 1ye6:C, 1ye6:D, 1z9a:A, 1z9a:B, 1z9a:C, 1z9a:D
15 8a18:CCC 570 112 0.0769 0.0596 0.3036 7.8 5a6t:C, 4ac7:C, 7b58:CCC, 7b59:CCC, 7b5a:CCC, 4ceu:C, 4cex:C, 5fsd:C, 5fse:C, 6g48:C, 6h8j:C, 6i9y:C, 1ie7:C, 5ol4:C, 7p7n:CCC, 7p7o:CCC, 8q2e:C, 6qdy:C, 6rkg:C, 6rp1:C, 1s3t:C, 1ubp:C, 2ubp:C, 3ubp:C, 4ubp:C, 7zcy:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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