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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AIPKIASYPLPVSLPTNKVDWRIDASRAVLLIHNMQEYFVHYFDSQAEPIPSLIKHIQQLKAHAKQAGIPVVYTAQPANQ
DPAERALLSDFWGPGLSEETAIIAPLAPESGDVQLTKWRYSAFKKSPLLDWLRETGRDQLIITGVYAHIGILSTALDAFM
FDIQPFVIGDGVADFSLSDHEFSLRYISGRTGAVKSTQQACLEIA

The query sequence (length=205) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3tb4:A 205 204 0.9902 0.9902 0.9951 4.76e-151 3tg2:A
2 2fq1:A 279 201 0.4927 0.3620 0.5025 5.37e-69
3 3r77:B 206 209 0.4439 0.4417 0.4354 1.54e-56 3r77:A
4 1nf8:A 207 209 0.4293 0.4251 0.4211 3.03e-55
5 3s2s:A 182 80 0.1415 0.1593 0.3625 1.37e-08 3s2s:B, 3s2s:C, 3s2s:D
6 1nba:A 253 155 0.2049 0.1660 0.2710 9.67e-08 1nba:B, 1nba:C, 1nba:D
7 3eef:A 173 144 0.1854 0.2197 0.2639 1.94e-07 3eef:B
8 6kua:A 163 79 0.1366 0.1718 0.3544 2.71e-07
9 8bkd:F 224 69 0.1171 0.1071 0.3478 2.36e-06 8bkd:C, 8bkd:D, 8bkd:G, 8bkd:H, 8bkd:J, 8bkd:K, 8bkd:L
10 6a8l:A 183 79 0.1317 0.1475 0.3418 3.54e-06 6a8l:B, 5zn8:A, 5zn8:B
11 3o93:A 190 79 0.1268 0.1368 0.3291 1.08e-04 3o90:A, 3o90:B, 3o90:C, 3o90:D, 3o91:A, 3o91:B, 3o91:C, 3o91:D, 3o92:A, 3o92:B, 3o92:C, 3o92:D, 3o93:B, 3o93:C, 3o93:D, 3o94:A, 3o94:B, 3o94:C, 3o94:D
12 1im5:A 179 74 0.1073 0.1229 0.2973 5.14e-04
13 8cib:D 196 131 0.1805 0.1888 0.2824 0.011 8cib:F
14 6xje:B 220 187 0.1902 0.1773 0.2086 0.012 6xj4:B, 6xje:A, 6xje:C, 6xje:D
15 6xjm:D 230 199 0.1951 0.1739 0.2010 0.037 6xjm:A, 6xjm:B, 6xjm:C
16 3pl1:A 185 62 0.0976 0.1081 0.3226 0.10
17 7ag6:A 302 77 0.1171 0.0795 0.3117 0.43 7ag6:B, 7agh:C, 7agh:D, 7agh:A, 7agh:B, 7agk:A, 7agk:B, 7agk:C
18 6i9a:A 453 26 0.0634 0.0287 0.5000 0.48 6i9a:B, 4rbm:A, 4tkx:L
19 1m21:A 487 57 0.0976 0.0411 0.3509 0.54 1m21:B
20 2wta:A 212 65 0.0927 0.0896 0.2923 1.3 2wt9:A, 2wt9:B
21 5hwg:A 175 95 0.1268 0.1486 0.2737 1.3 5hwh:A
22 3jck:G 257 26 0.0439 0.0350 0.3462 1.6 3j47:V, 4o8x:B, 4ocl:B, 4ocl:E, 4ocm:B, 4ocm:E, 4owp:B, 5u4p:B, 5w83:B
23 4wgf:A 202 73 0.0976 0.0990 0.2740 3.2 4wgf:E, 4wgf:B, 4wgf:H, 4wgf:C, 4wgf:G, 4wgf:D, 4wgf:F
24 7mys:A 239 41 0.0732 0.0628 0.3659 4.2 7mys:B
25 6o5f:A 417 80 0.1122 0.0552 0.2875 6.4 6o5f:B
26 7liu:A 442 80 0.1122 0.0520 0.2875 7.6 6cz5:A, 5e7j:A, 5e7m:A, 2i4i:A, 7liu:B, 4px9:A, 4px9:B, 4px9:C, 4pxa:A, 8ssw:A, 8ssw:B
27 4kdr:A 208 102 0.1268 0.1250 0.2549 7.7 5dpm:A
28 6six:B 437 68 0.1171 0.0549 0.3529 9.8 6siw:A, 6siw:B, 6six:A, 6siy:A, 6siy:B, 6siz:A, 6siz:B, 6tm4:AAA, 6tm4:BBB, 6wuq:A, 6wuq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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