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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATQQNNIGMVVIRGNSIIMLEALERV

The query sequence (length=71) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6v4x:G 77 73 1.0000 0.9221 0.9726 4.74e-46 7a5p:k, 7a5p:g, 7abg:k, 7abi:k, 6ah0:n, 6ahd:S, 6ahd:f, 6ahd:n, 7b0y:h, 8c6j:r, 8c6j:g, 8ch6:m, 8ch6:9, 7dvq:g, 7dvq:n, 7evo:d, 9fmd:n, 9fmd:g, 8h6e:5f, 8h6e:4f, 8h6e:2f, 8h6j:5f, 8h6j:4f, 8h6j:2f, 8h6k:5f, 8h6k:4f, 8h6k:2f, 8h6l:5f, 8h6l:4f, 8h6l:2f, 8hk1:d, 8i0p:k, 8i0r:k, 8i0s:f, 8i0s:k, 8i0t:k, 8i0u:f, 8i0u:k, 8i0v:k, 8i0w:n, 6icz:g, 6id0:g, 6id1:g, 5mqf:k, 5mqf:d, 5o9z:k, 4pjo:G, 4pjo:g, 4pjo:U, 4pjo:u, 8q7q:g, 8q7v:g, 8q7w:g, 8q7x:g, 8q91:n, 6qdv:r, 6qdv:g, 8qo9:2g, 8qo9:4g, 7qtt:m, 6qw6:4g, 6qw6:5g, 6qx9:1g, 6qx9:5g, 6qx9:2g, 6qx9:4g, 8qxd:2g, 8qxd:4g, 8qxd:5g, 8qzs:5g, 8qzs:2g, 8qzs:4g, 8r08:1g, 8r08:2g, 8r08:4g, 8r08:5g, 8r09:2g, 8r09:5g, 8r09:4g, 8r0a:5g, 8r0a:2g, 8r0a:4g, 8r0b:2g, 8r0b:4g, 8r0b:5g, 8rc0:n, 8rm5:2g, 8rm5:5g, 8rm5:4g, 8ro2:g, 7vpx:d, 7vpx:n, 7w59:g, 7w59:n, 7w5a:g, 7w5a:n, 7w5b:g, 7w5b:n, 4wzj:G, 4wzj:N, 4wzj:U, 4wzj:GG, 4wzj:NN, 4wzj:UU, 4wzj:GGG, 4wzj:NNN, 4wzj:UUU, 4wzj:GGGG, 4wzj:NNNN, 4wzj:UUUU, 5xjc:g, 5xjc:n, 6y53:k, 6y5q:k, 8y6o:g, 8y6o:n, 8y6o:u, 8y7e:n, 5yzg:g, 5yzg:n, 5z56:g, 5z56:n, 5z57:g, 5z57:n, 5z58:g, 5z58:n
2 8ro0:n 77 73 0.6479 0.5974 0.6301 1.56e-29 8ro0:g, 8ro1:g
3 6exn:r 75 71 0.5634 0.5333 0.5634 1.15e-19 7b9v:r, 7b9v:g, 6bk8:d, 7dco:k, 6exn:g, 6g90:g, 6g90:y, 5gam:g, 5gan:r, 5gan:g, 5gao:r, 5gm6:j, 5gmk:j, 5gmk:x, 6j6g:j, 6j6g:x, 6j6h:j, 6j6h:x, 6j6n:j, 6j6n:x, 6j6q:j, 6j6q:x, 5lj3:g, 5lj5:g, 5mps:g, 5mq0:g, 6n7p:Q, 6n7r:Q, 6n7x:Q, 5nrl:y, 5nrl:r, 5nrl:g, 7oqb:y, 7oqc:g, 7oqe:y, 8w2o:Q, 5wsg:j, 5wsg:K, 5y88:d, 5y88:k, 5ylz:d, 5ylz:k, 5zwm:V, 5zwm:k, 5zwn:g, 5zwo:k
4 3jb9:J 73 72 0.4507 0.4384 0.4444 1.34e-19 3jb9:o
5 4m7a:F 66 63 0.3662 0.3939 0.4127 2.51e-12
6 6bk8:f 80 68 0.3239 0.2875 0.3382 6.63e-08 6bk8:k, 7dco:a, 7dco:h, 6exn:k, 6exn:b, 6g90:s, 5gam:b, 5gan:k, 5gan:b, 5gao:k, 5gm6:k, 5gmk:k, 5gmk:s, 3jcm:S, 5lj3:b, 5lj5:b, 5mps:b, 5mq0:k, 5mq0:b, 5nrl:s, 5nrl:k, 5nrl:b, 7oqb:s, 7oqe:s, 5wsg:k, 5wsg:F, 5y88:a, 5y88:h, 5ylz:a, 5ylz:h, 5zwm:P, 5zwm:a, 5zwm:h, 5zwo:a, 5zwo:P
7 5vsu:C 81 71 0.3239 0.2840 0.3239 2.55e-07 6aso:C, 4c8q:C, 5gan:3, 4m7a:J, 4m7a:C, 4m7d:J, 4m7d:C, 5nrl:3
8 3jb9:H 76 48 0.2394 0.2237 0.3542 5.95e-07 3jb9:m
9 6ppq:F 71 71 0.3380 0.3380 0.3380 2.95e-06 6ppn:F, 6ppn:N, 6ppp:F, 6ppp:N, 6ppv:F
10 6n7r:K 124 62 0.2958 0.1694 0.3387 3.87e-06 7b9v:k, 7b9v:b, 6g90:b, 6j6g:k, 6j6g:s, 6j6h:k, 6j6h:s, 6j6n:k, 6j6n:s, 6j6q:k, 6j6q:s, 6n7p:K, 6n7x:K, 7oqc:b, 7oqe:b, 8w2o:K, 5zwn:a
11 1i5l:C 74 63 0.2817 0.2703 0.3175 3.90e-06 1i5l:E, 1i5l:F, 1i5l:G, 1i5l:J, 1i5l:K, 1i5l:L, 1i5l:A, 1i5l:B, 1i5l:H
12 1loj:C 77 53 0.2676 0.2468 0.3585 4.57e-06 1loj:A, 1loj:B, 1loj:D, 1loj:E, 1loj:F, 1loj:G, 1loj:H, 1loj:I, 1loj:J, 1loj:K, 1loj:L, 1loj:M, 1loj:N
13 6qw6:68 95 69 0.2394 0.1789 0.2464 7.93e-06 6ahd:z, 8h6e:6g, 8h6j:6g, 8h6k:6g, 8h6l:6g, 6qx9:68, 8qxd:68, 8r08:68, 8r09:68, 8r0a:68, 8r0b:68, 8rm5:68
14 8ro0:e 80 50 0.2676 0.2375 0.3800 1.61e-05 8ro1:e
15 3jb9:E 98 60 0.2817 0.2041 0.3333 1.68e-05 3jb9:b
16 6ppq:A 69 69 0.2817 0.2899 0.2899 1.79e-05 6ppv:A
17 6qw6:66 72 64 0.2676 0.2639 0.2969 2.12e-05 6qx9:66
18 7b9v:p 77 51 0.2394 0.2208 0.3333 6.91e-05 7b9v:e, 6bk8:c, 7dco:i, 6exn:p, 6exn:e, 6g90:e, 6g90:w, 5gan:p, 5gao:p, 5gm6:i, 5gmk:i, 5gmk:u, 6j6g:i, 6j6g:u, 6j6h:i, 6j6h:u, 6j6n:i, 6j6n:u, 6j6q:i, 6j6q:u, 5mps:e, 5mq0:e, 6n7p:O, 6n7r:O, 6n7x:O, 5nrl:w, 5nrl:p, 5nrl:e, 7oqb:w, 7oqc:e, 7oqe:w, 8w2o:O, 5wsg:i, 5wsg:G, 5y88:b, 5y88:i, 5ylz:b, 5ylz:i, 5zwm:T, 5zwm:i, 5zwn:e, 5zwo:T, 5zwo:i
19 6ppn:H 94 66 0.2676 0.2021 0.2879 1.35e-04 6ppn:P, 6ppp:H, 6ppp:P
20 7abg:j 81 49 0.1972 0.1728 0.2857 2.14e-04 7a5p:j, 7a5p:e, 7abi:j, 6ah0:c, 6ahd:e, 7b0y:g, 8c6j:p, 8c6j:e, 8ch6:i, 8ch6:1, 7dvq:e, 7dvq:l, 9fmd:l, 9fmd:e, 8h6e:5e, 8h6e:4e, 8h6j:5e, 8h6j:4e, 8h6k:5e, 8h6l:5e, 8i0p:e, 8i0p:j, 8i0r:e, 8i0r:j, 8i0s:e, 8i0s:j, 8i0t:e, 8i0t:j, 8i0u:e, 8i0u:j, 8i0v:e, 8i0v:j, 8i0w:e, 8i0w:l, 6icz:e, 6id0:e, 6id1:e, 5mqf:j, 5mqf:c, 5o9z:j, 4pjo:E, 4pjo:e, 4pjo:S, 4pjo:s, 8q7q:e, 8q7v:e, 8q7w:e, 8q7x:e, 6qdv:p, 6qdv:e, 8qo9:2e, 8qo9:5e, 8qo9:4e, 7qtt:i, 6qw6:4e, 6qw6:5e, 6qx9:1e, 6qx9:5e, 6qx9:2e, 6qx9:4e, 8qxd:2e, 8qxd:4e, 8qzs:5e, 8qzs:2e, 8qzs:4e, 8r08:1e, 8r08:2e, 8r08:4e, 8r09:2e, 8r09:5e, 8r09:4e, 8r0a:5e, 8r0a:2e, 8r0a:4e, 8r0b:4e, 8r0b:5e, 8rm5:2e, 8rm5:5e, 8rm5:4e, 8ro2:e, 6v4x:E, 7vpx:l, 7w59:e, 7w59:l, 7w5a:e, 7w5a:l, 7w5b:e, 7w5b:l, 4wzj:E, 4wzj:L, 4wzj:S, 4wzj:EE, 4wzj:LL, 4wzj:SS, 4wzj:EEE, 4wzj:LLL, 4wzj:SSS, 4wzj:EEEE, 4wzj:LLLL, 4wzj:SSSS, 5xjc:e, 5xjc:l, 8y6o:e, 8y6o:l, 8y6o:s, 8y7e:l, 5yzg:e, 5yzg:l, 5z56:e, 5z56:l, 5z57:e, 5z57:l, 5z58:e, 5z58:l
21 6v4x:B 76 56 0.2254 0.2105 0.2857 3.65e-04
22 9fmd:b 87 61 0.2254 0.1839 0.2623 8.35e-04 7a5p:m, 7a5p:b, 7abg:f, 7abi:f, 6ah0:U, 8ch6:n, 5o9z:f, 6qdv:b, 7qtt:n, 4wzj:I, 4wzj:P, 4wzj:BB, 4wzj:II, 4wzj:PP, 4wzj:BBB, 4wzj:III, 4wzj:PPP, 4wzj:BBBB, 4wzj:IIII, 4wzj:PPPP
23 8ro0:f 72 64 0.2676 0.2639 0.2969 0.001 8ro1:f
24 8ro0:b 98 58 0.2254 0.1633 0.2759 0.002 8ro1:b
25 1lnx:A 74 64 0.2535 0.2432 0.2812 0.003 1lnx:B, 1lnx:C, 1lnx:D, 1lnx:E, 1lnx:F, 1lnx:G
26 5mkn:d 72 58 0.1972 0.1944 0.2414 0.003 5mki:C, 5mki:D, 5mki:E, 5mki:F, 5mki:G, 5mki:I, 5mki:J, 5mki:K, 5mki:L, 5mkn:A, 5mkn:G, 5mkn:B, 5mkn:C, 5mkn:D, 5mkn:E, 5mkn:F, 5mkn:H, 5mkn:I, 5mkn:J, 5mkn:K, 5mkn:L, 5mkn:M, 5mkn:N, 5mkn:O, 5mkn:P, 5mkn:Q, 5mkn:R, 5mkn:T, 5mkn:U, 5mkn:V, 5mkn:W, 5mkn:X, 5mkn:Y, 5mkn:Z, 5mkn:a, 5mkn:b
27 5gan:4 74 51 0.2394 0.2297 0.3333 0.005 4m7a:N, 4m7a:G, 4m7d:N, 5nrl:j, 5vsu:D
28 5nrl:l 99 57 0.2254 0.1616 0.2807 0.011 6bk8:h, 7dco:m, 6exn:h, 6g90:t, 5gam:h, 5gan:l, 5gan:h, 5gao:l, 5gm6:m, 5gmk:m, 5gmk:z, 5lj3:h, 5lj3:l, 5lj5:h, 5lj5:l, 5mps:h, 5mq0:h, 5nrl:t, 5nrl:h, 7oqb:t, 7oqe:t, 5wsg:m, 5wsg:V, 5y88:f, 5y88:m, 5ylz:f, 5ylz:m, 5zwm:Q, 5zwm:m, 5zwo:Q, 5zwo:m
29 6tfl:A 62 60 0.1972 0.2258 0.2333 0.017 6tfl:B, 6tfl:C, 6tfl:D, 6tfl:E, 6tfl:F, 6tfl:G, 6tfl:H, 6tfl:I, 6tfl:J, 6tfl:K, 6tfl:L, 6tfl:M, 6tfl:N
30 7w59:b 102 68 0.2254 0.1569 0.2353 0.094 7abg:m, 7abi:m, 6ahd:a, 7b0y:j, 8c6j:b, 8ch6:8, 7dvq:i, 9fmd:i, 8h6e:5a, 8h6e:4a, 8h6j:5a, 8h6j:4a, 8h6k:5a, 8h6l:5a, 8i0p:a, 8i0p:m, 8i0r:a, 8i0r:m, 8i0s:m, 8i0t:a, 8i0t:m, 8i0u:m, 8i0v:a, 8i0v:m, 8i0w:a, 8i0w:i, 6icz:i, 4pjo:B, 4pjo:b, 4pjo:P, 4pjo:p, 8q7q:b, 8q7v:b, 8q7w:b, 8q7x:b, 8q91:h, 6qdv:k, 8qo9:5b, 8qo9:4b, 6qw6:4b, 6qw6:5b, 6qx9:1b, 6qx9:5b, 6qx9:2b, 6qx9:4b, 8qxd:4b, 8qxd:5b, 8qzs:5b, 8qzs:2b, 8r08:1b, 8r08:4b, 8r08:5b, 8r09:5b, 8r0a:5b, 8r0b:5b, 8rc0:h, 8rm5:2b, 8rm5:5b, 8ro2:b, 7vpx:k, 7w59:i, 7w5a:b, 7w5a:i, 7w5b:b, 7w5b:i, 4wzj:B, 5xjc:b, 5xjc:i, 8y6o:a, 8y6o:h, 8y6o:o, 8y7e:i, 5yzg:b, 5yzg:i, 5z56:b, 5z56:i, 5z57:b, 5z57:i, 5z58:b, 5z58:i
31 1m8v:A 72 63 0.2254 0.2222 0.2540 0.47 1m8v:M, 1m8v:C, 1m8v:K, 1m8v:F, 1m8v:H, 1m8v:E, 1m8v:I, 1m8v:D, 1m8v:J, 1m8v:B, 1m8v:L, 1m8v:G, 1m8v:N
32 3pm6:B 264 36 0.1549 0.0417 0.3056 0.52
33 3pm6:A 287 36 0.1549 0.0383 0.3056 0.60
34 3swn:A 76 46 0.2113 0.1974 0.3261 0.94 6ppq:E, 6ppv:E, 3swn:D, 3swn:P, 3swn:S
35 6ppn:B 94 32 0.1268 0.0957 0.2812 1.0 6ppn:J, 6ppp:B, 6ppp:J, 6ppq:B, 6ppv:B
36 6aso:D 59 32 0.1408 0.1695 0.3125 1.1
37 5vsu:B 98 61 0.1972 0.1429 0.2295 2.0 6aso:B, 5gan:2, 4m7a:I, 4m7a:B, 4m7d:I, 4m7d:B, 5nrl:a
38 8ro0:d 94 44 0.1831 0.1383 0.2955 2.0 8ro1:d
39 5vsu:F 77 39 0.1690 0.1558 0.3077 2.2 6aso:F
40 5zji:3 221 34 0.1549 0.0498 0.3235 2.4
41 2dc1:A 236 29 0.1690 0.0508 0.4138 4.6 2dc1:B
42 6b82:B 470 44 0.1690 0.0255 0.2727 5.1 6b82:A, 4r1z:A, 4r1z:B
43 5sze:A 71 44 0.1972 0.1972 0.3182 5.8
44 8y6o:q 104 53 0.1831 0.1250 0.2453 7.2 7a5p:h, 7abg:a, 7abi:a, 6ah0:k, 6ah0:P, 6ahd:P, 6ahd:k, 8ch6:l, 8ch6:4, 7dvq:k, 8h6e:2c, 8h6j:2c, 8h6k:4c, 8h6k:2c, 8h6l:4c, 8h6l:2c, 8i0w:k, 6id0:k, 6id1:k, 5o9z:h, 5o9z:a, 4pjo:R, 7qtt:l, 8qzs:42, 7w59:k, 7w5a:k, 7w5b:k, 5xjc:k, 8y7e:k, 5yzg:k, 5z56:k, 5z57:k, 5z58:k
45 2o7d:A 515 29 0.1408 0.0194 0.3448 7.3 2o7d:D, 2o7d:B, 2o7d:C, 2o7d:E, 2o7d:H, 2o7d:F, 2o7d:G, 2o7e:A, 2o7e:D, 2o7e:B, 2o7e:C, 2o7e:E, 2o7e:H, 2o7e:F, 2o7e:G
46 2h0k:A 318 59 0.2394 0.0535 0.2881 8.9 2h0k:B, 2h0l:A, 2ie6:A, 2ie7:A, 1n41:A, 1n42:A, 1n44:A, 2ran:A
47 5l8r:3 221 34 0.1408 0.0452 0.2941 9.0 7dkz:3, 8j6z:3, 8j7a:3, 8j7b:3, 3lw5:3, 7wfd:A3, 7wfe:B3, 7wg5:A3, 7wg5:B3, 2wsc:3, 2wse:3, 2wsf:3, 4xk8:3, 4xk8:8, 4y28:3, 6yac:3, 6yez:3, 6zoo:3, 6zxs:3
48 4zv4:A 392 60 0.2958 0.0536 0.3500 9.2 4zv4:B
49 3a7a:A 337 13 0.0845 0.0178 0.4615 9.9 3a7a:C, 3a7r:A, 4tvw:A, 4tvw:B, 4tvw:C, 4tvw:D, 4tvy:A, 4tvy:B, 1x2h:A, 1x2h:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218