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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AGRRAACGAVLLTELLERAAFYGITSNLVLFLNGAPFCWEGAQASEALLLFMGLTYLGSPFGGWLADARLGRARAILLSL
ALYLLGMLAFPLLAAPATRAALCGSARLLNCTAARCCSPATFAGLVLVGLGVATVKANITPFGADQVKDRGPEATRRFFN
WFYWSINLGAILSLGGIAYIQQNVSFVTGYAIPTVCVGLAFVVFLCGQSVFITKPPDGSAFTDMFKILFTEEKVEDVKAL
VKIVPVFLALIPYWTVYFQMQTTYVLQSLHLRIPEISNITTTPHTLPAAWLTMFDAVLILLLIPLKDKLVDPILRRHGLL
PSSLKRIAVGMFFVMCSAFAAGILESKRLNLVKEKTINQTIGNVVYHAADLSLWWQVPQYLLIGISEIFASIAGLEFAYS
AAPKSMQSAIMGLFFFFSGVGSFVGSGLLALVSIKAIGWMSSHTDFGNINGCYLNYYFFLLAAIQGATLLLFLIISVKYD
HHRDHQ

The query sequence (length=486) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8qsk:A 523 508 0.9918 0.9216 0.9488 0.0 8qsk:C, 8qsl:A, 8qsl:C, 8wx5:A
2 8jzs:B 486 489 0.9547 0.9547 0.9489 0.0 8jzs:A, 8jzu:A, 8wx4:B, 8wx4:A
3 8jzx:A 455 480 0.9095 0.9714 0.9208 0.0 8jzx:B
4 5a2o:A 470 507 0.2819 0.2915 0.2702 1.16e-36
5 9bis:A 472 455 0.2346 0.2415 0.2505 3.00e-36 9bir:A, 9bit:A, 9biu:A
6 7pmy:A 657 365 0.1728 0.1279 0.2301 1.18e-23
7 7pmy:A 657 57 0.0473 0.0350 0.4035 5.77e-07
8 7pmx:A 657 394 0.1790 0.1324 0.2208 7.17e-22 7pmw:A
9 7pmx:A 657 57 0.0412 0.0304 0.3509 1.30e-04 7pmw:A
10 6ei3:A 511 233 0.1296 0.1233 0.2704 6.56e-19
11 6ei3:A 511 211 0.1111 0.1057 0.2559 5.46e-08
12 4uvm:A 505 206 0.1152 0.1109 0.2718 1.72e-16
13 4uvm:A 505 213 0.1132 0.1089 0.2582 7.01e-11
14 4ikz:A 485 455 0.2037 0.2041 0.2176 6.22e-09
15 6fmr:A 475 492 0.2016 0.2063 0.1992 7.43e-08 4d2b:A, 4d2d:A, 5d58:A, 5d59:A, 6eia:A, 6fmy:A, 6ghj:A, 5oxl:A, 5oxm:A, 5oxn:A, 5oxo:A, 5oxq:A, 4xnj:A, 6yof:A, 6yog:A
16 7q0m:A 482 475 0.2284 0.2303 0.2337 3.38e-07
17 5oxp:A 462 210 0.0926 0.0974 0.2143 1.08e-04 7ac6:A, 4d2c:A, 5d6k:A, 5oxk:A, 4xni:A
18 6gz9:A 488 213 0.0988 0.0984 0.2254 0.001 6exs:A, 6hzp:A
19 4tpg:A 459 196 0.0926 0.0980 0.2296 0.012 4lep:A, 4lep:B, 4tph:A, 4tpj:B, 4tpj:A
20 6gs4:A 468 194 0.0864 0.0897 0.2165 0.11
21 8b17:A 451 167 0.0864 0.0931 0.2515 0.66 8b18:A, 8b19:A, 8b1a:A, 8b1b:A, 8b1c:A, 8b1d:A, 8b1e:A, 8b1f:A, 8b1g:A, 8b1h:A, 8b1i:A, 8b1j:A, 8b1k:A
22 4hln:A 504 61 0.0350 0.0337 0.2787 1.4
23 3wir:A 756 34 0.0288 0.0185 0.4118 1.6 3wiq:A, 3wir:B, 3wir:C, 3wir:D
24 5dcy:A 366 38 0.0267 0.0355 0.3421 4.4 5cob:A, 5cob:B, 5cob:C, 5cob:D, 5dbf:A, 5dbf:B, 5dbg:A, 5dbg:B, 5dbi:A, 5dbi:B, 5dcu:A, 5dcu:B, 5dcy:B, 5df1:A, 5df1:B, 5emh:A
25 7am2:CA 537 34 0.0226 0.0205 0.3235 6.8
26 5i78:A 305 22 0.0226 0.0361 0.5000 8.5 5i79:A, 5i79:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218