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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AGKLERVDPTTVRQEGPWADPAQAVVQTGPNQYTVYVLAFAFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEGTNINVE
VLPGEVSTVRYTFKRPGEYRIICNQYCGLGHQNMFGTIVVKE

The query sequence (length=122) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ajz:B 167 122 1.0000 0.7305 1.0000 9.13e-89 3bvd:B, 2cua:A, 2cua:B, 1ehk:B, 3eh3:B, 3eh4:B, 3eh5:B, 4fa7:B, 4faa:B, 2fwl:B, 4g70:B, 4g71:B, 4g72:B, 4g7q:B, 4g7r:B, 4g7s:B, 4gp4:B, 4gp5:B, 4gp8:B, 8hua:B, 8k65:B, 8k6y:B, 4n4y:B, 5ndc:B, 3qjq:B, 3qjr:B, 3qjs:B, 3qjt:B, 3qju:B, 3qjv:B, 2qpd:B, 2qpe:B, 3s33:B, 3s38:B, 3s39:B, 3s3a:B, 3s3b:B, 3s3c:B, 3s3d:B, 3s8f:B, 3s8g:B, 5u7n:A, 5u7n:B, 5u7n:C, 5u7n:D, 5u7n:E, 5u7n:F, 5u7n:G, 5u7n:H, 1xme:B
2 6ptt:A 119 119 0.8689 0.8908 0.8908 1.29e-74 6ptt:B, 6pty:A, 6pty:B
3 7deg:B 147 126 0.3689 0.3061 0.3571 2.31e-23 7deg:E
4 2yev:B 319 74 0.2131 0.0815 0.3514 3.47e-10 2yev:E
5 9f8x:A 572 128 0.2951 0.0629 0.2812 5.14e-10 9f8x:B, 9f8x:C, 9f8x:D, 1qni:A, 1qni:B, 1qni:C, 1qni:D, 1qni:E, 1qni:F
6 8dh6:b 236 64 0.1967 0.1017 0.3750 4.88e-09 8e7s:P, 8e7s:p, 8ec0:P, 6giq:b, 6hu9:b, 6hu9:n, 6t0b:b, 6t0b:o, 6t15:b, 6ymx:b, 6ymy:b, 7z10:b
7 5i5m:B 576 113 0.2541 0.0538 0.2743 2.70e-08 5i5m:A
8 7aq4:B 588 113 0.2459 0.0510 0.2655 4.57e-08 7apy:A, 7apy:B, 7aq0:A, 7aq0:B, 7aq2:A, 7aq2:B, 7aq3:A, 7aq3:B, 7aq4:A, 7aq5:A, 7aq5:B, 7aq6:A, 7aq6:B, 7aq7:A, 7aq7:B, 7aq8:A, 7aq8:B, 7aq9:A, 7aq9:B, 7aqa:A, 7aqa:B, 7qba:H, 7qba:I, 6rkz:A, 6rkz:B, 6rl0:A, 6rl0:B, 6rl0:C, 6rl0:D, 3sbp:A, 3sbp:B, 3sbp:C, 3sbp:D, 3sbp:E, 3sbp:F, 3sbp:G, 3sbp:H, 3sbq:A, 3sbq:B, 3sbr:A, 3sbr:B, 3sbr:C, 3sbr:D, 3sbr:E, 3sbr:F, 3sbr:G, 3sbr:H, 6y6y:A, 6y6y:B, 6y71:A, 6y71:B, 6y72:A, 6y72:B, 6y77:A, 6y77:B, 6y7d:A, 6y7d:B, 6y7e:A, 6y7e:B
9 5z62:B 227 68 0.1885 0.1013 0.3382 1.85e-07
10 8c8q:B 238 68 0.1721 0.0882 0.3088 1.15e-06 8q1b:b
11 1fwx:A 591 103 0.2295 0.0474 0.2718 2.49e-06 1fwx:B, 1fwx:C, 1fwx:D, 2iwf:A, 2iwf:B, 2iwk:A, 2iwk:B
12 7jro:b 239 68 0.1639 0.0837 0.2941 8.32e-06 7jrp:b
13 4w9z:A 138 68 0.1475 0.1304 0.2647 1.03e-05
14 3abk:B 227 68 0.1557 0.0837 0.2794 1.09e-05 3abk:O, 3abl:B, 3abl:O, 3abm:B, 3abm:O, 3ag1:B, 3ag1:O, 3ag2:B, 3ag2:O, 3ag3:B, 3ag3:O, 3ag4:B, 3ag4:O, 3asn:B, 3asn:O, 3aso:B, 3aso:O, 5b1a:B, 5b1a:O, 5b1b:B, 5b1b:O, 5b3s:B, 5b3s:O, 7coh:B, 7coh:O, 7cp5:B, 7cp5:O, 8d4t:O, 7d5w:B, 7d5w:O, 7d5x:B, 7d5x:O, 7dgq:C1, 7dgr:C4, 7dgs:B9, 7dkf:B3, 2dyr:B, 2dyr:O, 2dys:B, 2dys:O, 2eij:B, 2eij:O, 2eik:B, 2eik:O, 2eil:B, 2eil:O, 2eim:B, 2eim:O, 2ein:B, 2ein:O, 7ev7:B, 7ev7:O, 8gbt:B, 8gbt:O, 8gcq:B, 8gcq:O, 5gpn:z, 5gup:Al, 8gvm:B, 8gvm:O, 8h8r:B, 8h8r:O, 8h8s:B, 8h8s:O, 8ijn:B, 8ijn:O, 5iy5:B, 5iy5:O, 5j4z:BO, 5j7y:BO, 6j8m:B, 6j8m:O, 6juw:B, 6juw:O, 6jy3:B, 6jy4:B, 5luf:y, 6nkn:B, 6nkn:O, 6nmf:B, 6nmf:O, 6nmp:B, 6nmp:O, 7o37:b, 7o3c:b, 7o3e:b, 1occ:B, 1occ:O, 1oco:B, 1oco:O, 1ocr:B, 1ocr:O, 1ocz:B, 1ocz:O, 2occ:B, 2occ:O, 8pw5:o, 8pw5:b, 8pw6:o, 8pw7:o, 7thu:B, 7thu:O, 7tie:B, 7tie:O, 7tih:B, 7tih:O, 7tii:B, 7tii:O, 8ugh:4B, 8ugi:4B, 8ugj:4B, 8ugj:8B, 8ugl:4B, 8ugn:4B, 8ugn:8B, 8ugr:4B, 8ugr:8B, 1v54:B, 1v54:O, 1v55:B, 1v55:O, 7vuw:B, 7vuw:O, 7vvr:B, 7vvr:O, 7w3e:B, 7w3e:O, 5w97:B, 5w97:b, 5wau:B, 5wau:b, 3wg7:B, 3wg7:O, 5x19:B, 5x19:O, 5x1b:B, 5x1b:O, 5x1f:B, 5x1f:O, 3x2q:B, 3x2q:O, 5xdq:B, 5xdq:O, 5xdx:B, 5xdx:O, 7xma:B, 7xma:O, 7xmb:B, 7xmb:O, 5xth:y, 5xti:y, 5xti:By, 7y44:B, 7y44:O, 2y69:B, 2y69:O, 2ybb:M, 7ypy:B, 7ypy:O, 5z84:B, 5z84:O, 5z85:B, 5z85:O, 5z86:B, 5z86:O, 5zco:B, 5zco:O, 5zcp:B, 5zcp:O, 5zcq:B, 5zcq:O, 2zxw:B, 2zxw:O
15 1ar1:B 252 62 0.1475 0.0714 0.2903 7.10e-05 7ate:B, 7atn:B, 7au3:B, 7au6:B, 3ehb:B, 3hb3:B, 1qle:B
16 8iuf:C2 196 70 0.1803 0.1122 0.3143 1.53e-04 8iuj:c2, 8iuj:C2
17 1m56:B 260 55 0.1230 0.0577 0.2727 2.53e-04 6ci0:D, 6ci0:B, 3dtu:D, 3dtu:B, 3fye:B, 3fye:D, 3fyi:B, 3fyi:D, 2gsm:B, 2gsm:D, 1m56:H, 1m57:B, 1m57:H, 3om3:B, 3om3:D, 3oma:B, 3oma:D, 3omi:B, 3omi:D, 3omn:B, 3omn:D, 6pw0:B, 6pw0:D, 6pw1:B, 6pw1:D, 5weh:B, 5weh:H
18 8b6h:DB 604 64 0.1311 0.0265 0.2500 0.010 8b6h:Db, 8bqs:DB, 8bqs:Db, 8gym:c2, 8gym:C2, 8gzu:27, 8gzu:82, 8gzu:c2, 8gzu:C2, 7w5z:C2, 7w5z:c2
19 8ovc:Q 286 74 0.1967 0.0839 0.3243 0.011 7e1v:E, 7e1v:Q, 7e1w:E, 7e1w:Q, 7e1x:E, 7e1x:Q, 6hwh:P, 6hwh:L
20 6adq:E 312 74 0.1967 0.0769 0.3243 0.012 6adq:Q, 8ovc:X, 8ovd:Q, 8ovd:X, 7rh5:Q, 7rh5:K, 7rh6:Q, 7rh6:K, 7rh7:Q, 7rh7:K
21 8qqk:B 263 68 0.1475 0.0684 0.2647 0.016 1cyx:A, 1fft:B, 8go3:B, 7n9z:G, 6wti:B, 7xmc:B, 7xmd:B
22 1bxu:A 91 84 0.2131 0.2857 0.3095 0.034 1bxv:A
23 3wi9:A 303 129 0.2623 0.1056 0.2481 0.13 6l46:A, 3wia:A, 3wia:B, 3wia:C, 3wia:D, 3wia:E, 3wia:F, 3wia:G, 3wia:H, 3wia:I, 3wkp:A, 3wkq:A, 3wni:A, 3wnj:A, 3x1e:A, 3x1f:A, 3x1g:A, 3x1n:A, 4ysa:A, 4ysd:A, 4yso:A, 4ysp:A, 4ysq:A, 4ysr:A, 4yss:A, 4yst:A, 4ysu:A, 5ytl:A, 5ytm:A, 5ytn:A, 4zk8:A
24 1cc3:A 130 42 0.1066 0.1000 0.3095 0.25 1ag0:A, 1ag0:B, 1azn:A, 1azn:B, 1azn:C, 1azn:D, 1azr:A, 1azr:B, 1azr:C, 1azr:D, 1azu:A, 2azu:A, 2azu:B, 2azu:C, 2azu:D, 3azu:A, 3azu:B, 3azu:C, 3azu:D, 4azu:A, 4azu:B, 4azu:C, 4azu:D, 5azu:A, 5azu:B, 5azu:C, 5azu:D, 1bex:A, 1bex:B, 4bww:A, 4bww:B, 4bww:C, 4bww:D, 1cc3:B, 1e5y:A, 1e5y:B, 1e5y:C, 1e5y:D, 1e5z:A, 1e5z:B, 1e5z:C, 1e5z:D, 1e67:A, 1e67:B, 1e67:C, 1e67:D, 1etj:A, 1etj:B, 1etj:C, 1etj:D, 1ezl:A, 1ezl:B, 1ezl:C, 8f5k:A, 8f5k:B, 8f5k:C, 8f5k:D, 8f5l:A, 8f5l:B, 2fnw:A, 2fnw:B, 3fpy:A, 3fq1:A, 3fq2:A, 3fqy:A, 3fs9:A, 3fsa:A, 3fsv:A, 3fsw:A, 3fsw:B, 3fsw:C, 3fsw:D, 3fsz:A, 3fsz:B, 3ft0:A, 3ft0:B, 2ghz:A, 2ghz:B, 2gi0:A, 2gi0:B, 1gr7:A, 1gr7:B, 1gr7:C, 1gr7:D, 6gyi:A, 6gyi:B, 6gyi:C, 6gyi:D, 4hhg:A, 4hhw:A, 4hhw:B, 4hip:A, 4hip:B, 2hx7:A, 2hx7:B, 2hx8:A, 2hx8:B, 2hx9:A, 2hx9:B, 2hxa:A, 2hxa:B, 4hz1:B, 4hz1:C, 5i26:A, 5i26:B, 5i26:C, 5i26:D, 5i28:A, 5i28:B, 5i28:C, 5i28:D, 5i28:E, 5i28:F, 5i28:G, 5i28:H, 5i28:I, 5i28:J, 5i28:K, 5i28:L, 5i28:M, 5i28:N, 5i28:O, 5i28:P, 1i53:A, 1i53:B, 2i7o:A, 2i7s:A, 2i7s:B, 2i7s:C, 2i7s:D, 6iav:A, 6iav:B, 6iav:C, 6iav:D, 3ibo:A, 3ibo:B, 3ibo:C, 3ibo:D, 2idf:A, 2idf:B, 1ils:A, 1ils:B, 1ils:C, 1ils:D, 1ilu:A, 1ilu:B, 1ilu:C, 1ilu:D, 1ilu:E, 1ilu:F, 1ilu:G, 1ilu:H, 1ilu:I, 1ilu:K, 1ilu:L, 1ilu:M, 3in0:A, 3in0:B, 3in0:C, 3in0:D, 3in2:A, 2iwe:A, 2iwe:J, 2iwe:D, 2iwe:G, 4jkn:A, 4jkn:B, 4jkn:C, 4jkn:D, 3jt2:A, 3jt2:B, 3jtb:A, 3jtb:B, 3jtb:C, 3jtb:D, 1jvl:A, 1jvl:B, 1jvo:A, 1jvo:B, 1jvo:C, 1jvo:D, 1jvo:E, 1jvo:F, 1jvo:G, 1jvo:H, 1jvo:I, 1jvo:J, 1jvo:K, 1jvo:L, 1jze:A, 1jzf:A, 1jzg:A, 1jzh:A, 1jzi:A, 1jzi:B, 1jzj:A, 1jzj:B, 4k9j:A, 4ko5:A, 4ko5:B, 4ko6:A, 4ko6:B, 4ko6:C, 4ko6:D, 4ko7:A, 4ko7:B, 4ko7:C, 4ko7:D, 4ko9:A, 4ko9:B, 4ko9:C, 4ko9:D, 4kob:A, 4kob:B, 4kob:C, 4kob:D, 4koc:A, 4mfh:A, 4mfh:B, 4mfh:C, 6mjr:A, 6mjr:C, 6mjr:B, 6mjr:D, 6mjs:A, 6mjs:D, 6mjs:B, 6mjs:C, 6mjt:A, 6mjt:B, 3n2j:A, 3n2j:B, 3n2j:C, 3n2j:D, 3n2j:E, 3n2j:F, 3n2j:G, 3n2j:H, 3n2j:I, 3n2j:J, 3n2j:K, 3n2j:L, 3np3:A, 3np4:A, 1nzr:A, 1nzr:B, 1nzr:C, 1nzr:D, 2oj1:A, 2oj1:B, 3oqr:A, 4qkt:A, 4qkt:B, 4qlw:B, 4qlw:D, 1r1c:A, 1r1c:B, 1r1c:C, 1r1c:D, 7tc5:A, 7tc5:B, 7tc6:A, 7tc6:B, 7tnc:A, 2tsa:A, 2tsa:B, 2tsa:C, 2tsa:D, 2tsb:A, 2tsb:B, 2tsb:C, 2tsb:D, 3u25:A, 3u25:B, 7u2f:A, 1vlx:A, 1vlx:B, 1vlx:C, 1vlx:D, 4wkx:A, 4wkx:B, 1xb3:A, 1xb3:B, 1xb6:A, 1xb6:B, 1xb8:A, 1xb8:C, 2xv0:A, 2xv2:A, 2xv3:A, 2xv3:B
25 1iby:A 112 69 0.1393 0.1518 0.2464 0.86 1iby:B, 1iby:C, 1iby:D, 1ibz:A, 1ibz:B, 1ibz:C, 1ibz:D, 1ic0:A, 1ic0:B, 1ic0:C, 1ic0:D, 1ic0:E, 1ic0:F
26 5iku:A 240 70 0.1639 0.0833 0.2857 1.4 4hpk:A, 4hpk:B, 1nqd:A, 1nqd:B, 2o8o:A, 2o8o:B
27 4hcf:B 96 79 0.1639 0.2083 0.2532 1.7 4hcf:A, 4hcg:A, 4hcg:B
28 4dp0:X 99 91 0.1885 0.2323 0.2527 1.7 4dp1:X, 4dp2:X, 4dp4:X, 4dp5:X, 4dp6:X
29 2p6e:C 446 45 0.1311 0.0359 0.3556 1.7 1iic:A, 1iic:B, 1iid:A, 2nmt:A, 2p6e:A, 2p6e:B, 2p6e:D, 2p6e:E, 2p6e:F, 2p6f:A, 2p6f:B, 2p6f:C, 2p6f:D, 2p6f:E, 2p6f:F, 2p6g:A, 2p6g:B, 2p6g:C, 2p6g:D, 2p6g:E, 2p6g:F
30 4rks:B 320 37 0.1148 0.0437 0.3784 1.7 4rks:A, 4rkz:A, 4rkz:B
31 1g71:A 344 47 0.1393 0.0494 0.3617 2.9 1g71:B
32 1g55:A 313 64 0.1393 0.0543 0.2656 2.9
33 4aq6:D 427 49 0.1148 0.0328 0.2857 3.4 4aq2:A, 4aq2:B, 4aq2:C, 4aq2:D, 4aq2:E, 4aq2:F, 4aq2:G, 4aq2:H, 4aq2:I, 4aq2:J, 4aq2:K, 4aq2:L, 4aq6:A, 4aq6:B, 4aq6:C, 4aq6:E, 4aq6:F, 4aq6:G, 4aq6:H, 4aq6:I, 4aq6:J, 4aq6:K, 4aq6:L, 3zds:A, 3zds:B, 3zds:C, 3zds:D, 3zds:E, 3zds:F, 3zds:G, 3zds:H, 3zds:I, 3zds:J, 3zds:K, 3zds:L
34 1ag6:A 99 93 0.1803 0.2222 0.2366 3.4 1oow:A, 2pcf:A, 1tef:A, 1tef:B, 1teg:A, 1teg:B, 1ylb:B
35 4u3e:A 637 47 0.1148 0.0220 0.2979 6.2 4coi:A, 4coi:B, 4coj:A, 4coj:B, 4col:A, 4col:B, 4com:A, 4com:B, 4u3e:B
36 5zl1:A 306 58 0.1393 0.0556 0.2931 6.4 5zl1:B, 5zl1:C, 5zl1:D
37 6xov:A 966 32 0.0738 0.0093 0.2812 6.6
38 4rpu:A 988 32 0.0738 0.0091 0.2812 7.0 4l3t:A, 4l3t:B, 4nge:A, 4nge:D, 4rpu:B
39 4ri6:A 214 23 0.0574 0.0327 0.3043 7.1 4ri6:B, 4ri7:A, 4ri7:B
40 8r3p:A 672 71 0.1803 0.0327 0.3099 7.3 8r3p:B, 8r3p:C, 8r3p:D
41 3tu6:A 127 82 0.1639 0.1575 0.2439 8.2
42 8ix7:B 221 64 0.1066 0.0588 0.2031 8.8 8ix7:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218