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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEM
LQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPK
NKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKV
SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGG
NSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLG

The query sequence (length=388) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8uto:N 389 388 1.0000 0.9974 1.0000 0.0 2hxh:C, 1i5s:A, 8utn:K, 8utn:N, 8uto:K, 8utp:K, 8utp:N, 8utq:K, 8utr:K, 8utt:K, 8utt:N, 8utu:K, 8utv:K, 8uty:K, 8uty:N, 4uxp:C, 1vfz:A
2 7eo9:A 351 380 0.8995 0.9943 0.9184 0.0 7eob:A, 2hxf:C, 1i6i:A, 1ia0:K, 1vfv:A, 1vfw:A, 1vfx:A, 2zfi:A, 2zfj:A, 2zfk:A, 2zfl:A, 2zfm:A
3 6a20:A 395 382 0.5567 0.5468 0.5654 1.92e-139 6a1z:A, 7d8v:A, 3gbj:B, 5zbr:B, 5zbr:A, 5zbr:C, 5zbs:B, 5zbs:A
4 5zbs:C 323 369 0.5155 0.6192 0.5420 7.88e-130 3gbj:A, 3gbj:C
5 6wwk:K 368 377 0.4948 0.5217 0.5093 2.32e-122 7lvq:K, 7lvr:K, 6wwf:K, 6wwg:K, 6wwg:N, 6wwh:K, 6wwh:N, 6wwj:K, 6wwk:N, 6wwl:K, 6wwl:N, 6wwm:K, 6wwn:K, 6wwo:K, 6wwq:K, 6wwr:K, 6wws:K, 6wwu:K, 6wwv:K
6 7wrg:A 812 389 0.5103 0.2438 0.5090 6.99e-121
7 7wrg:B 783 388 0.5000 0.2478 0.5000 1.08e-117
8 2owm:A 328 368 0.5000 0.5915 0.5272 3.68e-116 2owm:B, 2owm:C, 2owm:D
9 4ozq:B 687 349 0.4485 0.2533 0.4986 1.15e-102 4ozq:A
10 7a5e:A 338 364 0.4046 0.4645 0.4313 1.88e-89 7a5e:B
11 1goj:A 354 361 0.4124 0.4520 0.4432 2.51e-85
12 3b6u:B 343 375 0.3995 0.4519 0.4133 3.20e-84 3b6u:A
13 3zfd:A 340 367 0.3840 0.4382 0.4060 1.47e-80 3zfc:A
14 5ocu:K 333 350 0.3737 0.4354 0.4143 1.52e-77 5ogc:K
15 4uy0:C 333 359 0.3686 0.4294 0.3983 8.80e-77
16 5hnw:K 329 348 0.3711 0.4377 0.4138 1.31e-75 5hle:A, 5hny:K, 3x2t:B
17 6zpi:C 332 364 0.3814 0.4458 0.4066 2.21e-75 4bn2:A, 4bn2:B, 6zph:B
18 7tr1:K 346 375 0.3943 0.4422 0.4080 3.29e-74 7lff:A, 7lff:B
19 1mkj:A 336 361 0.3608 0.4167 0.3878 6.31e-74 4atx:C, 1bg2:A, 4hna:K, 8ixa:Y, 8ixa:S, 8ixa:T, 8ixa:U, 8ixa:V, 8ixa:W, 8ixa:X, 8ixa:Z, 8ixa:a, 8ixb:l, 8ixb:g, 8ixb:k, 8ixb:m, 8ixd:Y, 8ixd:S, 8ixd:T, 8ixd:U, 8ixd:V, 8ixd:W, 8ixd:X, 8ixd:Z, 8ixd:a, 8ixe:l, 8ixe:h, 8ixe:p, 8ixe:q, 8ixf:Y, 8ixf:S, 8ixf:T, 8ixf:U, 8ixf:V, 8ixf:W, 8ixf:X, 8ixf:Z, 8ixf:a, 8ixg:l, 8ixg:h, 8ixg:p, 8ixg:q, 3j8y:K, 2p4n:K
20 4aqv:C 361 371 0.3557 0.3823 0.3720 3.54e-71 4a28:A, 4a50:A, 4a5y:A, 4a5y:C, 4as7:A, 4b7b:A, 4bbg:A, 4bxn:A, 4bxn:B, 3cjo:A, 3cjo:B, 4ck6:C, 4ck7:C, 2fky:A, 2fky:B, 2fl2:A, 2fl2:B, 2fl6:A, 2fl6:B, 2fme:B, 2g1q:A, 2g1q:B, 6g6z:A, 6hkx:B, 3hqd:A, 3hqd:B, 2ieh:A, 2ieh:B, 1ii6:A, 1ii6:B, 3k3b:A, 3k3b:B, 3k5e:A, 3ken:A, 3l9h:A, 3l9h:B, 2pg2:A, 2pg2:B, 1q0b:A, 1q0b:B, 2q2y:A, 2q2y:B, 2q2z:A, 2q2z:B, 6ta4:K, 6tle:A, 6tle:B, 6trl:B, 2uyi:A, 2uyi:B, 2uym:A, 2uym:B, 2wog:A, 2wog:B, 2wog:C, 2x2r:A, 2x2r:C, 2x7c:A, 2x7c:B, 2x7d:A, 2x7d:B, 2x7e:A, 2x7e:B, 1x88:A, 1x88:B, 2xae:C, 1yrs:A, 1yrs:B, 4zca:A, 4zhi:A, 4zhi:B, 5zo7:A, 5zo7:B
21 7a3z:A 307 362 0.3634 0.4593 0.3895 1.20e-69
22 6ta3:K 334 367 0.3505 0.4072 0.3706 2.11e-69 4a1z:A, 4a1z:B, 4a28:B, 4a51:A, 4a51:B, 4a51:C, 4a51:D, 4ap0:A, 2fme:A, 6g6y:A, 2gm1:A, 2gm1:E, 6hkx:A, 6hky:A, 6hky:B, 3k5e:B, 6tiw:K, 2x2r:B, 2xae:A, 2xae:B, 6y1i:A, 6y1i:B, 6y1i:C, 8yhh:A, 3zcw:A, 4zca:B
23 7rs5:K 346 371 0.3737 0.4191 0.3908 3.78e-69 7rs5:a, 7rs5:b, 7rs5:c, 7rs5:d, 7rs5:e, 7rs5:f, 7rs5:g, 7rs5:h, 7rs6:K, 7rs6:a, 7rs6:b, 7rs6:c, 7rs6:d, 7rs6:e, 7rs6:f, 7rs6:g, 7rs6:h
24 3b6v:A 306 370 0.3557 0.4510 0.3730 4.11e-69 3b6v:B
25 7rx0:C 328 355 0.3376 0.3994 0.3690 3.58e-68 6mlq:C, 6mlr:C
26 2vvg:B 309 367 0.3892 0.4887 0.4114 4.21e-68 2vvg:A
27 7tr3:K 418 297 0.3299 0.3062 0.4310 5.23e-68 7tqx:K, 7tqy:K, 7tr0:K
28 3x2t:A 311 363 0.3634 0.4534 0.3884 5.27e-66 2kin:A, 3kin:A, 3kin:C
29 4bn2:C 311 362 0.3505 0.4373 0.3757 8.09e-66
30 7lxr:B 344 371 0.3428 0.3866 0.3585 8.86e-66 7lxr:A, 6vpo:C, 2wbe:C
31 2y65:C 343 363 0.3557 0.4023 0.3802 1.41e-63 2y5w:A, 2y5w:B, 2y65:D, 2y65:B, 2y65:A
32 1t5c:A 322 370 0.3557 0.4286 0.3730 2.17e-63 8hfh:A, 6m4i:A, 6m4i:B, 1t5c:B
33 7z2b:K 308 348 0.3222 0.4058 0.3592 2.23e-63
34 5zo8:A 331 373 0.3402 0.3988 0.3539 2.10e-62 4a51:G, 4a51:E, 4a51:F, 4a5y:B, 4ap0:D, 4ap0:B, 2gm1:B, 2gm1:D, 6hky:C, 6trl:A, 8yhh:B, 5zo8:B, 5zo9:A, 5zo9:B
35 7x4n:E 332 367 0.3351 0.3916 0.3542 3.37e-61
36 5wde:A 320 350 0.3351 0.4062 0.3714 1.15e-60
37 7nba:K 331 357 0.3273 0.3837 0.3557 2.55e-60
38 4ap0:C 311 364 0.3273 0.4084 0.3489 1.21e-59
39 3lre:B 300 349 0.3402 0.4400 0.3782 1.97e-59 3lre:A, 7rsi:C
40 6s8m:K 344 386 0.3402 0.3837 0.3420 1.88e-57
41 3cob:A 355 320 0.3041 0.3324 0.3688 2.14e-57 3cob:C, 1sdm:A
42 5m5i:C 369 397 0.3454 0.3631 0.3375 3.89e-57 5m5l:C, 5m5m:C, 5m5n:C, 5m5o:C
43 7n61:0X 420 399 0.3608 0.3333 0.3509 1.12e-56 7n61:0Y, 7n61:0Z, 7n61:1A
44 2xt3:A 300 351 0.3144 0.4067 0.3476 6.21e-55 4a14:A
45 5mm7:K 397 339 0.3170 0.3098 0.3628 4.86e-54 5mm4:K
46 5gsz:A 306 355 0.3222 0.4085 0.3521 9.48e-53
47 3wpn:A 309 368 0.3196 0.4013 0.3370 7.66e-52
48 5mio:C 477 357 0.3402 0.2767 0.3697 1.55e-51 1v8j:A, 5xjb:A
49 5nd4:C 337 365 0.3093 0.3561 0.3288 1.34e-50
50 3h4s:A 359 378 0.3144 0.3398 0.3228 7.69e-50 4frz:A, 4frz:B
51 5xja:A 337 356 0.3247 0.3739 0.3539 4.81e-49 3edl:D, 2heh:A, 4ubf:B, 4ubf:C, 4ubf:D, 1v8k:A, 5xja:B, 5xjb:B, 4y05:A
52 6b0l:K 368 361 0.3222 0.3397 0.3463 1.02e-48 6b0c:K
53 3t0q:A 304 350 0.2990 0.3816 0.3314 6.84e-48
54 6bbn:E 378 357 0.3402 0.3492 0.3697 8.00e-48 2gry:A
55 4gkr:B 307 281 0.2603 0.3290 0.3594 3.33e-45 4gkr:A
56 4etp:A 379 361 0.3015 0.3087 0.3241 9.57e-45 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
57 1cz7:D 365 349 0.3067 0.3260 0.3410 1.26e-44 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
58 6nje:A 297 353 0.3093 0.4040 0.3399 3.30e-44
59 3cnz:A 333 382 0.3067 0.3574 0.3115 5.21e-43 3cnz:B
60 5nd7:C 300 350 0.2912 0.3767 0.3229 1.26e-42
61 5wdh:A 296 351 0.2912 0.3818 0.3219 6.70e-42
62 3u06:B 344 343 0.2938 0.3314 0.3324 2.00e-41 3l1c:B, 1n6m:B
63 3nwn:A 308 304 0.2680 0.3377 0.3421 2.93e-40
64 4ubf:A 309 355 0.3119 0.3916 0.3408 1.24e-38
65 4h1g:A 670 275 0.2552 0.1478 0.3600 1.62e-37
66 1f9w:A 300 279 0.2294 0.2967 0.3190 5.38e-35 1f9w:B
67 3dcb:A 299 357 0.2732 0.3545 0.2969 8.38e-35 3dc4:A, 3dco:N, 3pxn:A
68 5nd2:C 280 348 0.2680 0.3714 0.2989 2.00e-34
69 8bjs:A 343 395 0.2629 0.2974 0.2582 1.15e-27
70 5w3d:B 313 345 0.2655 0.3291 0.2986 4.28e-27
71 6zz6:D 1050 54 0.0464 0.0171 0.3333 0.20
72 5a0m:B 227 38 0.0361 0.0617 0.3684 2.1 5a0m:A, 3c0w:A, 3c0x:A, 3ool:A, 3oor:A, 1r7m:A, 1r7m:B
73 6f0x:B 398 107 0.0644 0.0628 0.2336 2.2 6f0x:A, 6f0x:C, 6f0x:D, 6f0x:E, 7l9p:A, 7l9p:B, 7l9p:C, 7l9p:D, 7l9p:E
74 1hsl:A 238 66 0.0387 0.0630 0.2273 4.4 1hsl:B
75 2cks:B 306 50 0.0438 0.0556 0.3400 6.7 2ckr:B, 2ckr:A, 2cks:A
76 1a4e:A 488 71 0.0464 0.0369 0.2535 7.3 1a4e:B, 1a4e:C, 1a4e:D
77 4ib2:A 247 59 0.0438 0.0688 0.2881 7.7 4ib2:B
78 7obr:x 488 62 0.0490 0.0389 0.3065 8.8 2go5:W, 2j37:W, 5l3q:A, 5l3q:C, 1mfq:C, 7nfx:x, 7qwq:x, 1ry1:W, 4ue5:D, 6y2z:A, 6y32:A, 6y32:C, 6y32:E, 6y32:G
79 3jaj:z 426 62 0.0490 0.0446 0.3065 9.0 6frk:x, 3jan:z, 7obq:x, 6r6g:AB
80 7wfd:A6 212 36 0.0309 0.0566 0.3333 9.8 7wg5:A6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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