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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AGAARSLSRFRGCLAGALLGDCVGSFYEAHDTVDLTSVLRHVEALYYTDDTAMARALVQSLLAKEAFDEVDMAHRFAQEY
KKDPDRGYGAGVVTVFKKLLNPKCRDVFEPARAQFNGKGSYGNGGAMRVAGISLAYSSVQDVQKFARLSAQLTHASSLGY
NGAILQALAVHLALQGESSSEHFLKQLLGHMEDLEGDAQSVLDARELGMEERPYSSRLKKIGELLDQASVTREEVVSELG
NGIAAFESVPTAIYCFLRCMEPDPEIPSAFNSLQRTLIYSISLGGETDTIATMAGAIAGAYYGMDQVPESWQQSCEGYEE
TDILAQSLHRVFQK

The query sequence (length=334) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6d3a:A 347 349 0.9940 0.9568 0.9513 0.0 7akr:AAA, 7akr:BBB, 7akr:CCC, 7akr:DDD, 7aks:AAA, 7aks:CCC, 7aks:EEE, 7aks:GGG, 7arw:A, 7arw:B, 6d36:C, 6d36:D, 6d36:A, 6d36:B, 6d3a:C, 6d3a:D, 6d3a:B, 2foz:A, 2fp0:A, 2fp0:B, 2g4k:A, 7l9f:C, 7l9f:D, 7l9f:A, 7l9f:B, 7l9h:C, 7l9h:D, 7l9h:A, 7l9h:B, 7l9i:C, 7l9i:D, 7l9i:A, 7l9i:B, 2qty:A, 2qty:B, 5zqy:A
2 6g1q:B 331 342 0.6437 0.6495 0.6287 1.59e-150 7aqm:A, 7aqm:B, 6g1p:A, 6g1p:B, 6g1q:A, 6hgz:A, 6hgz:B, 6hh3:A, 6hh3:B, 6hh4:A, 6hh4:B, 6hh5:A, 6hh5:B, 6hoz:A, 6hoz:B
3 1t5j:A 301 340 0.2275 0.2525 0.2235 1.01e-14
4 2yzv:A 286 333 0.2485 0.2902 0.2492 8.75e-14
5 6dre:A 365 339 0.2186 0.2000 0.2153 6.02e-08 6drh:C
6 3o5t:A 295 333 0.2126 0.2407 0.2132 9.31e-06 3g9d:A, 3g9d:B, 5ovo:A
7 2woc:A 291 56 0.0569 0.0653 0.3393 4.02e-05 2woc:B, 2woc:C, 2wod:A, 2wod:B, 2woe:A, 2woe:C, 2woe:B
8 2woc:A 291 131 0.1138 0.1306 0.2901 0.001 2woc:B, 2woc:C, 2wod:A, 2wod:B, 2woe:A, 2woe:C, 2woe:B
9 4zqb:B 316 141 0.0988 0.1044 0.2340 0.38 4zqb:A
10 3mg9:A 255 78 0.0689 0.0902 0.2949 1.5 3mgc:A
11 5epo:A 261 117 0.0868 0.1111 0.2479 2.2 5epo:B, 5epo:C, 5epo:D
12 4ghl:A 132 101 0.0719 0.1818 0.2376 3.9 4gha:A, 4gha:E, 4gha:G, 4gha:C, 4ghl:D, 4ghl:B, 4ghl:C
13 8ckh:A 281 57 0.0599 0.0712 0.3509 6.4 8ckh:B
14 6g2a:A 361 129 0.1108 0.1025 0.2868 6.9 6g28:A, 3hfw:A, 6iux:A
15 2a5z:C 244 77 0.0778 0.1066 0.3377 8.4 2a5z:A, 2a5z:B
16 6sna:A 265 61 0.0449 0.0566 0.2459 8.9 6sna:B, 6sna:F, 6sna:G, 6sna:J, 6sna:K, 6sna:N, 6sna:X
17 5li6:A 377 41 0.0479 0.0424 0.3902 9.3 5li6:B, 5li7:A, 5li7:B
18 7pua:FP 348 32 0.0359 0.0345 0.3750 9.4 6sga:FP, 6sgb:FP
19 5lie:B 397 41 0.0479 0.0403 0.3902 9.8 5li8:A, 5lie:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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