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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AFRIEKDTMGEVQVPADKYWAAQTERSRNNFKIGPAASMPHEIIEAFGYLKKAAAFANTDLGVLPAEKRDLIGQACDEIL
ARKLDDQFPLVIWQTGSGTQSNMNLNEVIANRAHVINGGKLGEKSIIHPNDDVNKSQSSNDTYPTAMHIAAYKKVVEATI
PAVERLQKTLAAKAAEFKDVVKIGRTHLMDATPLTLGQEFSGYAAQLSFGLTAIKNTLPHLRQLALGGTAVGTGLNTPKG
YDVKVAEYIAKFTGLPFITAENKFEALATHDAIVETHGALKQVAMSLFKIANDIRLLASGPRSGIGEILIPENEPGCSIM
PGKVNPTQCEAMTMVAAQVLGNDTTISFAGSQGHFELNVFKPVMAANFLQSAQLIADVCISFDEHCATGIQPNTPRIQHL
LDSSLMLVTALNTHIGYENAAKIAKTAHKNGTTLREEAINLGLVSAEDFDKWVVPADMVG

The query sequence (length=460) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7c18:B 464 460 1.0000 0.9914 1.0000 0.0 7c18:A, 7c18:C, 7c18:D
2 7lub:B 462 461 0.6261 0.6234 0.6247 0.0 7lub:A
3 1fuo:A 456 456 0.6043 0.6096 0.6096 0.0 1fuo:B, 1fup:A, 1fup:B, 1fuq:A, 1fuq:B
4 4apb:D 462 455 0.5152 0.5130 0.5209 3.00e-149 4adl:A, 4adl:C, 4adl:B, 4adl:D, 4apb:A, 4apb:C, 4apb:B, 5f91:A, 5f91:C, 6s43:A, 6s43:C, 6s7k:A, 6s7k:C, 6s7s:A, 6s7s:C, 6s7u:A, 6s7u:C, 6s7w:A, 6s7w:C, 6s7z:A, 6s7z:C, 6s88:A, 6s88:C
5 3r6v:G 463 457 0.4391 0.4363 0.4420 2.06e-131 3r6q:A, 3r6q:D, 3r6q:E, 3r6q:H, 3r6v:A, 3r6v:B, 3r6v:C, 3r6v:D, 3r6v:E, 3r6v:F, 3r6v:H, 3r6y:F
6 6wng:A 466 459 0.4152 0.4099 0.4161 2.08e-112 6wng:B, 6wng:D, 6wng:C
7 3oce:A 461 443 0.4130 0.4121 0.4289 3.72e-112 3oce:B, 3oce:C, 3oce:D
8 2x75:A 427 183 0.1109 0.1194 0.2787 6.04e-09
9 1tj7:B 451 319 0.1652 0.1685 0.2382 7.40e-08
10 5eyt:A 472 240 0.1304 0.1271 0.2500 7.73e-08
11 2e9f:B 450 166 0.0957 0.0978 0.2651 6.07e-06 2e9f:A, 2e9f:D, 2e9f:C
12 1k7w:D 450 183 0.1022 0.1044 0.2568 2.35e-05 1dcn:D, 1hy0:A, 1hy0:B, 1k7w:A, 1k7w:C, 1k7w:B, 1tjw:A, 1tjw:B, 1tjw:C, 1tjw:D
13 5nx9:D 477 198 0.1109 0.1069 0.2576 5.29e-05 2j91:A, 2j91:D, 2j91:B, 2j91:C, 5nx9:A, 5nx9:B, 5nxa:A, 5nxa:B, 5nxa:D, 5nxa:E, 5nxa:G, 5nxa:H, 5nxa:F, 2vd6:A, 2vd6:D, 2vd6:B, 2vd6:C
14 2qga:C 455 177 0.1000 0.1011 0.2599 2.61e-04 2qga:B
15 6g3f:A 497 189 0.1152 0.1066 0.2804 6.78e-04 6g3g:A, 6g3h:A, 6g3i:A, 6rx8:A
16 4efc:A 452 212 0.1109 0.1128 0.2406 7.15e-04 4efc:B
17 4eei:B 423 79 0.0500 0.0544 0.2911 7.82e-04 4eei:A, 5hw2:A, 5hw2:C
18 5vkw:B 469 271 0.1391 0.1365 0.2362 0.001
19 5nx9:C 441 179 0.1000 0.1043 0.2570 0.011
20 5nxa:C 418 155 0.0870 0.0957 0.2581 0.023
21 3gzh:A 469 187 0.1022 0.1002 0.2513 0.023 2ptq:A, 2ptq:B, 2ptr:A, 2ptr:B
22 1rm6:B 323 108 0.0761 0.1084 0.3241 0.28 1rm6:E, 1sb3:B, 1sb3:E
23 9b8w:A 993 46 0.0391 0.0181 0.3913 0.33 9b8w:B, 9b8w:C, 9b8w:D, 9b8x:A, 9b8y:A, 9b8y:B, 9b8y:C, 9b8y:D, 9b8z:A, 9b90:A, 9b90:B, 9b90:C, 9b90:D, 9b91:A, 9b92:A, 9b92:B, 9b92:C, 9b92:D, 9b94:A, 9b94:B, 9b94:C, 9b94:D, 6bqr:A, 6bqr:C, 6bqr:B, 6bqr:D
24 4mx2:B 439 92 0.0587 0.0615 0.2935 1.4 4mx2:A, 4mx2:C, 4mx2:D, 4mx2:E, 4mx2:F, 4mx2:G, 4mx2:H
25 3pgy:B 404 50 0.0391 0.0446 0.3600 1.6 3pgy:A
26 6mfl:A 284 55 0.0435 0.0704 0.3636 1.7 6mfl:B
27 5wp6:A 977 47 0.0370 0.0174 0.3617 1.8 6bqv:A, 6bqv:C, 6bqv:B, 6bqv:D, 5wp6:B, 5wp6:C, 5wp6:D
28 7t29:A 453 48 0.0304 0.0309 0.2917 3.0
29 6bwi:A 816 37 0.0326 0.0184 0.4054 3.4 6bwi:D, 6bwi:B, 6bwi:C
30 1frv:B 530 97 0.0630 0.0547 0.2990 7.5 1frv:D, 2frv:L, 2frv:B, 2frv:D, 2frv:F, 2frv:H, 2frv:J, 1yq9:H, 1yq9:I

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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