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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
AFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDIICQIISSTITGDVVLAAAYSH
ELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYKGVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFG
ALKGASDGGLYVPHSENRFPGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIYT
SAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAG

The query sequence (length=294) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 4v6i:BQ 297 294 0.9966 0.9865 0.9966 0.0 8aaf:m, 8agt:m, 8agu:m, 8agv:m, 8agw:m, 8agx:m, 8agz:m, 5apn:D, 5apo:D, 7azy:t, 7b7d:LG, 8bip:LD, 8bjq:LD, 8bn3:L5, 8bqd:BI, 8bqx:BI, 7bt6:D, 7btb:D, 8ccs:HH, 8cdl:HH, 8cdr:HH, 8ceh:HH, 8cf5:HH, 8cg8:HH, 8cgn:HH, 8civ:HH, 8cku:HH, 8cmj:HH, 5dat:L5, 5dat:l5, 5dc3:L5, 5dc3:l5, 5dge:L5, 5dge:l5, 5dgf:L5, 5dgf:l5, 5dgv:L5, 5dgv:l5, 8eub:AD, 8evp:AD, 8evq:AD, 8evr:AD, 8evs:AD, 8evt:AD, 8ewb:AD, 8ewc:AD, 5fci:L5, 5fci:l5, 5fcj:L5, 5fcj:l5, 6ft6:D, 5gak:H, 6gq1:D, 6gqb:D, 6gqv:D, 5h4p:D, 6hd7:H, 8hfr:Ez, 6hhq:m, 6hhq:CG, 5i4l:L5, 5i4l:l5, 6i7o:BI, 6i7o:YI, 3j6x:L5, 3j6y:L5, 3j77:L5, 3j78:L5, 3jct:D, 5jcs:D, 5juo:I, 5jup:I, 5jus:I, 5jut:I, 5juu:I, 8k2d:LD, 8k82:LD, 5lyb:L5, 5lyb:l5, 5m1j:D5, 6m62:D, 5mc6:BI, 5mei:m, 5mei:CG, 7mpi:AD, 7mpj:AD, 6n8j:D, 6n8m:G, 6n8n:G, 6n8o:G, 7n8b:AD, 5ndg:L5, 5ndg:l5, 5ndv:L5, 5ndv:l5, 5ndw:L5, 5ndw:l5, 7nrc:LG, 7nrd:LG, 5obm:L5, 5obm:l5, 7oh3:D, 7ohq:D, 7oht:D, 6oig:D, 5on6:m, 5on6:CG, 7osa:uL18, 7osm:uL18, 8p8m:LI, 8p8n:LI, 8p8u:LI, 8pfr:LI, 6q8y:BI, 6qik:P, 6qt0:P, 6qtz:P, 6r84:H, 6r86:H, 6r87:H, 6ri5:P, 7rr5:LD, 6rzz:P, 6s05:P, 6s47:AG, 6snt:k, 6sv4:BI, 6sv4:YI, 6sv4:ZI, 6t4q:LD, 5t62:G, 5t6r:G, 6t7i:LD, 6t7t:LD, 6t83:Dy, 6t83:Ga, 5tbw:m, 5tbw:CG, 6tb3:BI, 5tga:L5, 5tga:l5, 5tgm:L5, 5tgm:l5, 6tnu:BI, 7too:AL05, 7top:AL05, 4u3m:L5, 4u3m:l5, 4u3n:L5, 4u3n:l5, 4u3u:L5, 4u3u:l5, 4u4n:L5, 4u4n:l5, 4u4o:L5, 4u4o:l5, 4u4q:L5, 4u4q:l5, 4u4r:L5, 4u4r:l5, 4u4u:L5, 4u4u:l5, 4u4y:L5, 4u4y:l5, 4u4z:L5, 4u4z:l5, 4u50:L5, 4u50:l5, 4u51:L5, 4u51:l5, 4u52:L5, 4u52:l5, 4u53:L5, 4u53:l5, 4u55:L5, 4u55:l5, 4u56:L5, 4u56:l5, 4u6f:L5, 4u6f:l5, 7ug6:D, 7uoo:D, 7uqb:D, 7uqz:D, 7v08:D, 4v4b:BE, 4v7h:BE, 4v7r:BE, 4v7r:DE, 4v88:BD, 4v88:DD, 4v8t:D, 4v8y:BD, 4v8z:BD, 4v91:D, 6woo:D, 6xiq:D, 6xir:D, 8y0u:LD, 7z34:D, 6z6j:LD, 6z6k:LD, 7zpq:BD, 7zrs:BD, 7zs5:BF, 7zuw:BD, 7zux:ED, 7zw0:LH
2 4v7f:P 269 294 0.9082 0.9926 0.9082 0.0 6n8k:D, 6n8l:D, 6ylg:D, 6ylh:D
3 5it7:DD 295 292 0.8776 0.8746 0.8836 0.0 6uz7:AD
4 8c3a:m 296 289 0.7789 0.7736 0.7924 4.75e-163 8c3a:AZ, 8cq7:m, 8cq7:AZ, 8cqw:m, 8cqw:AZ, 8cre:m, 8cre:AZ, 8oeq:m, 8oeq:AZ, 7pzy:m, 7q08:m, 7q0f:m, 7q0p:m, 7q0r:m, 8q5i:m
5 7r81:G1 300 298 0.7007 0.6867 0.6913 1.31e-148
6 7olc:LD 300 296 0.6667 0.6533 0.6622 3.28e-142 8i9r:LD, 7old:LD, 8oo0:LD, 8pv1:LD, 8pv2:LD, 8pv3:LD, 8pv4:LD, 8pv5:LD, 8pv6:LD, 8pv7:LD, 8pv8:LD, 8pvk:LD, 8pvl:LD, 7z3n:LD, 7z3o:LD
7 8eug:D 287 283 0.6224 0.6376 0.6466 4.47e-135 8eui:D
8 7ozs:A 275 282 0.6020 0.6436 0.6277 1.58e-127
9 4v6w:CD 290 285 0.5544 0.5621 0.5719 2.62e-112 6xu6:CD, 6xu7:CD, 6xu8:CD
10 8azw:h 288 291 0.5306 0.5417 0.5361 1.48e-107 8b2l:h3, 7qiw:G, 7qiz:G
11 7oya:D1 288 289 0.4898 0.5000 0.4983 1.82e-101 7oyb:D1
12 8q7z:BD 296 292 0.5034 0.5000 0.5068 2.27e-101 7a01:G2, 8a3d:G, 5aj0:AD, 8b5l:D, 8b6c:D, 9bdl:AL05, 9bdn:AL05, 9bdp:AL05, 8bgu:A, 7bhp:LD, 8bhf:m3, 8bpo:D2, 8btk:BD, 7cpu:LD, 7cpv:LD, 4d5y:D, 4d67:D, 6d90:D, 6d9j:D, 9f1b:B, 9f1c:B, 9f1d:B, 7f5s:LD, 8fl0:SB, 8fl2:SB, 8fl3:SB, 8fl4:SB, 8fl6:SB, 8fl7:SB, 8fl9:SB, 8fla:SB, 8flb:SB, 8flc:SB, 8fld:SB, 8fle:SB, 8flf:SB, 6frk:D, 6ftg:D, 6fti:D, 6ftj:D, 8g5y:LD, 8g5z:LD, 8g60:LD, 8g61:LD, 8g6j:LD, 8glp:LD, 6gz3:AD, 6gz4:AD, 6gz5:AD, 6hcf:D3, 6hcj:D3, 6hcm:D3, 6hcq:D3, 8idt:r, 8idy:r, 8ie3:r, 8ifd:1G, 8ife:1G, 8ine:r, 8inf:r, 8ink:R, 6ip5:1G, 6ip6:1G, 6ip8:1G, 8ipd:R, 8ipx:R, 8ipy:R, 3j7o:D, 3j7p:D, 3j7q:D, 3j7r:D, 3j92:D, 3jag:D, 3jah:D, 3jai:D, 3jaj:D, 3jan:D, 8jdj:J, 8jdk:J, 8jdl:J, 8jdm:J, 8k2c:LD, 5lks:LD, 6lqm:r, 6lsr:r, 6lss:r, 7ls1:G2, 7ls2:G2, 6lu8:r, 5lzs:D, 5lzt:D, 5lzu:D, 5lzv:D, 5lzw:D, 5lzx:D, 5lzy:D, 5lzz:D, 7mdz:D, 6mtb:D, 6mtc:D, 6mtd:D, 6mte:D, 7nfx:D, 7nwg:D3, 7nwh:D, 7nwi:D, 7o7y:BD, 7o7z:BD, 7o80:BD, 7o81:BD, 7obr:D, 8ohd:LD, 8oj0:LD, 8oj5:LD, 8oj8:LD, 6ole:F, 6olf:F, 6olg:AD, 6oli:F, 6olz:AD, 6om0:F, 6om7:F, 7ow7:G, 7oyc:D1, 7oyd:D, 8p2k:BD, 6p5i:AD, 6p5j:AD, 6p5k:AD, 6p5n:AD, 8q87:BD, 8qfd:D, 7qgg:F, 8qoi:LD, 7qvp:LD, 7qvp:MD, 7qwq:D, 7qwr:D, 7qws:D, 6qzp:LD, 6r5q:D, 6r6g:D, 6r6p:D, 6r7q:D, 8rjb:D, 8rjc:D, 8rjd:D, 8scb:D, 6sgc:D2, 6swa:D, 5t2c:G, 6t59:D3, 7tm3:D, 7toq:AL05, 7tor:AL05, 7tut:D, 7ucj:D, 7uck:D, 4ug0:LD, 4ujc:BD, 4ujd:AD, 4uje:CD, 4v5z:Bn, 4v6x:CD, 6w6l:F, 6xa1:LD, 7xnx:LD, 7xny:LD, 8xsx:LD, 8xsy:LD, 8xsz:LD, 6y0g:LD, 8y0w:LD, 8y0x:LD, 6y2l:LD, 6y57:LD, 6y6x:LD, 8yoo:LD, 8yop:LD, 6z6l:LD, 6z6m:LD, 6z6n:LD, 7zjw:LG, 7zjx:LG, 6zm7:LD, 6zme:LD, 6zmi:LD, 6zmo:LD, 6zvk:G2
13 4v3p:LQ 304 292 0.5204 0.5033 0.5240 8.50e-100 8ip8:KA, 8ipa:KA, 8ipb:KA, 8jiv:CD, 4v7e:CD
14 9bh5:CD 289 287 0.5170 0.5260 0.5296 7.65e-99 9cai:CD
15 4v8m:Bu 298 290 0.5102 0.5034 0.5172 5.64e-98 8ova:Bu, 8ove:Bu
16 6zj3:Ld 260 258 0.4626 0.5231 0.5271 3.27e-94
17 8rxh:LO 298 286 0.4932 0.4866 0.5070 3.76e-94 8a3w:O, 8a98:O, 6az3:O, 8ovj:O, 8rxx:LO
18 5t2a:s 266 258 0.4660 0.5150 0.5310 2.96e-92 3jcs:O
19 5xxb:D 261 285 0.4830 0.5441 0.4982 1.36e-91
20 4v8p:CM 300 296 0.4762 0.4667 0.4730 2.51e-85 4v8p:BM, 4v8p:EM, 4v8p:GM
21 8ir1:C 248 252 0.4388 0.5202 0.5119 1.46e-84 8ir3:C
22 3j79:R 252 247 0.4320 0.5040 0.5142 1.87e-83 3jbn:AR, 3jbo:AR, 3jbp:AR, 8tpu:AR, 5umd:R
23 8br8:LF 293 273 0.4626 0.4642 0.4982 2.78e-80 8brm:LF, 8bsi:LF, 8bsj:LF, 8btd:LF, 8btr:LF, 8fru:D, 7pwg:D, 7pwo:D2
24 7qep:L5 283 281 0.4422 0.4594 0.4626 1.39e-76
25 5t5h:u 193 244 0.4082 0.6218 0.4918 1.58e-76
26 5xy3:D 272 281 0.4422 0.4779 0.4626 5.24e-76
27 6zu5:LD0 258 280 0.4422 0.5039 0.4643 1.81e-72
28 6rm3:LD0 282 288 0.4490 0.4681 0.4583 2.39e-71
29 8p5d:LD0 281 287 0.4184 0.4377 0.4286 3.03e-70 8p60:LD0, 8p60:KD0, 7qca:LD0
30 3cc2:N 186 232 0.2585 0.4086 0.3276 1.24e-26 3cc4:N, 3cc7:N, 3cce:N, 3ccj:N, 3ccl:N, 3ccm:N, 3ccq:N, 3ccr:N, 3ccs:N, 3ccu:N, 3ccv:N, 3cd6:N, 3cma:N, 3cme:N, 3cpw:M, 3cxc:M, 1ffk:K, 3g4s:N, 3g6e:N, 3g71:N, 3i55:N, 3i56:N, 1jj2:M, 1k73:O, 1k8a:O, 1k9m:O, 1kc8:O, 1kd1:O, 1kqs:M, 1m1k:O, 1m90:O, 1n8r:O, 1nji:O, 2otj:N, 2otl:N, 3ow2:M, 1q7y:O, 1q81:O, 1q82:O, 1q86:O, 2qa4:N, 2qex:N, 1qvf:M, 1qvg:M, 1s72:N, 4v4p:AQ, 4v4r:BS, 4v4s:BS, 4v4t:BS, 4v9f:N, 1vq4:N, 1vq5:N, 1vq6:N, 1vq7:N, 1vq8:N, 1vq9:N, 1vqk:N, 1vql:N, 1vqm:N, 1vqn:N, 1vqo:N, 1vqp:N, 1w2b:M, 1yhq:N, 1yi2:N, 1yij:N, 1yit:N, 1yj9:N, 1yjn:N, 1yjw:N
31 4v4n:AO 197 215 0.2449 0.3655 0.3349 1.48e-22 4v6u:BO
32 8hku:L18P 193 218 0.2313 0.3523 0.3119 1.40e-21 8hkv:L18P, 8hky:L18P, 8hkz:L18P, 8hl1:L18P, 8hl2:L18P, 8hl3:L18P, 8hl4:L18P, 8hl5:L18P
33 6skf:BQ 164 157 0.1905 0.3415 0.3567 7.66e-12 6skg:BQ, 6th6:BQ
34 4kbl:A 395 50 0.0544 0.0405 0.3200 0.69 4kbl:B, 5udh:B
35 7jil:O 115 90 0.0952 0.2435 0.3111 0.77
36 7b5s:H 216 59 0.0578 0.0787 0.2881 0.83
37 5tte:B 442 50 0.0544 0.0362 0.3200 0.98 7b5m:H, 2m9y:A, 1wd2:A
38 7b5l:H 423 50 0.0544 0.0378 0.3200 0.99 7b5n:H, 4kc9:A, 5udh:A
39 7xcm:A 494 66 0.0680 0.0405 0.3030 1.6 7xcm:B, 7xcm:C, 7xcm:D, 7xcm:E, 7xcm:F, 7xcn:A, 7xcn:B, 7xcn:C, 7xcn:D, 7xcn:E, 7xcn:F
40 8rd8:Nc 113 60 0.0850 0.2212 0.4167 1.9 8rdv:Nc, 8rdw:Nc
41 8osc:B 126 70 0.0714 0.1667 0.3000 3.2 8osc:A
42 8cro:N 65 24 0.0408 0.1846 0.5000 5.0 8oki:N, 8orq:N, 8p2i:N, 8rbo:N
43 7k04:E 62 46 0.0442 0.2097 0.2826 7.2 7m2u:E
44 8btd:Sd 108 61 0.0578 0.1574 0.2787 9.6 8br8:Sd, 8brm:Sd, 8bsi:Sd, 8bsj:Sd, 8btr:Sd, 8fvy:a, 8g4s:a, 7pwf:a, 7pwo:a1
45 8qhq:A 143 70 0.0680 0.1399 0.2857 9.9 4p5e:A, 4p5e:B, 8qhq:B, 8qhq:C, 8qhq:D, 8qhq:E, 8qhq:F, 8qhr:A, 8qhr:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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