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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AFQETNPPAGPVRAIAEYERSAAVLVRYPFGIPMELIKELAKNDKVITIVASESQKNTVITQYTQSGVNLSNCDFIIAKT
DSYWTRDYTGWFAMYDTNKVGLVDFIYNRPRPNDDEFPKYEAQYLGIEMFGMKLKQTGGNYMTDGYGSAVQSHIAYTENS
SLSQAQVNQKMKDYLGITHHDVVQDPNGEYINHVDCWGKYLAPNKILIRKVPDNHPQHQALEDMAAYFAAQTCAWGTKYE
VYRALATNEQPYTNSLILNNRVFVPVNGPASVDNDALNVYKTAMPGYEIIGVKGASGTPWLGTDALHCRTHEVADKGYLY
IKHYPILGEQAGPDYKIEADVVSCANATISPVQCYYRINGSGSFKAADMTMESTGHYTYSFTGLNKNDKVEYYISAADNS
GRKETYPFIGEPDPFKFTCMNE

The query sequence (length=422) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6i0x:B 422 422 0.9929 0.9929 0.9929 0.0 5ak7:A, 5ak8:A, 6i0x:A, 4ytb:A, 4ytg:A
2 6nic:D 360 222 0.1280 0.1500 0.2432 2.46e-10 6nic:A, 6nic:C
3 3h7c:X 369 222 0.1090 0.1247 0.2072 5.06e-04 3h7k:A, 2q3u:A, 2q3u:B, 1vkp:A, 1vkp:B
4 1irx:B 508 49 0.0450 0.0374 0.3878 0.56 1irx:A
5 7r1n:AAA 184 81 0.0545 0.1250 0.2840 1.4 7r1n:BBB, 7r1n:CCC, 7r1n:DDD
6 3sz3:A 341 108 0.0687 0.0850 0.2685 1.6
7 5gz9:A 280 104 0.0569 0.0857 0.2308 2.4
8 6zej:I 351 64 0.0403 0.0484 0.2656 3.0 6alz:A, 6alz:B, 2bcd:A, 2bdx:A, 6czo:A, 6czo:C, 6dno:A, 8dwk:A, 8dwk:B, 8dwl:C, 8dwl:A, 3e7a:A, 3e7a:B, 3e7b:A, 3e7b:B, 3egg:A, 3egg:B, 3egh:A, 3egh:B, 1fjm:A, 1fjm:B, 6g0i:A, 6g0j:A, 4g9j:A, 4g9j:B, 6ghm:A, 6ghm:B, 3hvq:A, 3hvq:B, 1it6:A, 1it6:B, 1jk7:A, 4mov:A, 4mov:B, 4moy:A, 4mp0:C, 4mp0:A, 3n5u:A, 3n5u:B, 7nzm:B, 2o8g:A, 2o8g:B, 6obn:A, 6obn:B, 6obp:A, 6obq:A, 6obq:B, 6obr:A, 6obr:B, 6obs:A, 6obs:B, 6obu:A, 6obu:B, 7qfb:A, 7sd0:C, 8sw5:A, 8sw5:B, 8sw6:A, 8sw6:B, 7t0y:A, 7t0y:C, 7tvf:F, 7tvf:C, 7txh:C, 7txh:F, 1u32:A, 8u5g:A, 7upi:B, 4ut2:A, 4ut2:B, 4ut3:A, 4ut3:B, 4v0u:D, 4v0u:F, 4v0u:H, 4v0u:J, 4v0u:N, 4v0v:A, 4v0v:C, 4v0w:A, 4v0w:C, 4v0x:A, 3v4y:A, 3v4y:C, 3v4y:E, 3v4y:G, 4xpn:A, 4xpn:C, 6zee:P, 6zee:Q, 6zee:B, 6zee:A, 6zee:I, 6zee:K, 6zef:A, 6zef:B, 6zeg:A, 6zeg:B, 6zeh:A, 6zeh:B, 6zei:A, 6zei:B, 6zej:D, 6zej:A, 6zej:F, 6zej:L, 6zej:O, 6zk6:A, 5zqv:A, 5zqv:B, 5zqv:D, 5zqv:C, 5zt0:A, 5zt0:C, 5zt0:B, 5zt0:D, 5zt0:E, 5zt0:F
9 7ysu:C 211 85 0.0521 0.1043 0.2588 3.3 7ysu:E
10 7nm8:AAA 251 47 0.0379 0.0637 0.3404 4.2
11 7wh9:A 476 39 0.0332 0.0294 0.3590 4.5 7wh9:B, 7wh9:C
12 1x77:A 174 49 0.0403 0.0977 0.3469 5.5 1x77:B
13 4zxh:A 1314 62 0.0403 0.0129 0.2742 6.7 4zxi:A
14 1mr1:C 97 78 0.0498 0.2165 0.2692 7.1 1mr1:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218