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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AFKDDKAIELTIPMGKITIDVSKRWKCRIGIRRLKKFITKTFHDKEAEVQISPDLNKFLWERGMRNVPKRVRVRVNQEPY
PKDPSKKVYKLSHVVVSTFKGLGTEAIAE

The query sequence (length=109) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8p5d:LDD 109 109 1.0000 1.0000 1.0000 1.04e-77 8p60:LDD, 8p60:KDD, 7qca:LDD
2 6zu5:LDD 103 102 0.3578 0.3786 0.3824 1.94e-22
3 6rm3:LDD 102 103 0.3303 0.3529 0.3495 4.16e-16
4 7qep:O1 108 101 0.3211 0.3241 0.3465 2.76e-13
5 3j79:7 96 98 0.3119 0.3542 0.3469 2.43e-11 3jbn:A7, 3jbo:A7, 3jbp:A7, 8tpu:A7, 5umd:7
6 4v8p:BW 110 105 0.3119 0.3091 0.3238 3.87e-11 4v8p:CW, 4v8p:EW, 4v8p:GW
7 4v8m:Bh 188 109 0.3028 0.1755 0.3028 3.01e-10 8ova:Bh, 8ove:Bh
8 6zj3:Lt 111 105 0.3028 0.2973 0.3143 5.90e-10
9 8rxh:Le 186 107 0.2936 0.1720 0.2991 1.19e-08 8a3w:e, 8a98:e, 6az3:e, 3jcs:e, 8ovj:e, 8rxx:Le, 5t2a:f
10 4v6x:Cd 113 103 0.3211 0.3097 0.3398 2.21e-08 7a01:u2, 8a3d:X, 5aj0:Ad, 8b5l:d, 8b6c:d, 9bdl:AL31, 9bdn:AL31, 9bdp:AL31, 8bf9:d, 7bhp:Ld, 8bhf:Q1, 8bpo:c2, 8btk:Bd, 7cpu:Ld, 7cpv:Ld, 4d5y:d, 4d67:d, 6d90:d, 6d9j:d, 9f1b:Bd, 9f1c:Bd, 9f1d:Bd, 7f5s:Ld, 8fkv:LP, 8fkw:LP, 8fkx:LP, 8fky:LP, 8fkz:LP, 8fl2:LP, 8fl3:LP, 8fl4:LP, 8fl6:LP, 8fl7:LP, 8fl9:LP, 8fla:LP, 8flb:LP, 8flc:LP, 8fld:LP, 8fle:LP, 8flf:LP, 6frk:d, 6ftg:d, 6fti:d, 6ftj:d, 8g5y:Ld, 8g5z:Ld, 8g60:Ld, 8g61:Ld, 8g6j:Ld, 8glp:Ld, 6gz3:Ad, 6gz4:Ad, 6gz5:Ad, 6hcf:d3, 6hcj:d3, 6hcm:d3, 6hcq:d3, 8idt:j, 8idy:j, 8ie3:j, 8ifd:2X, 8ife:2X, 8ine:j, 8inf:j, 8ink:j, 6ip5:2X, 6ip6:2X, 6ip8:2X, 8ipd:j, 8ipx:j, 8ipy:j, 8ir1:j, 8ir3:j, 3j7o:d, 3j7p:d, 3j7q:d, 3j7r:d, 3j92:d, 3jag:d, 3jah:d, 3jai:d, 3jaj:d, 3jan:d, 8jdj:i, 8jdk:i, 8jdl:i, 8jdm:i, 8k2c:Ld, 5lks:Ld, 6lqm:T, 6lsr:T, 6lss:j, 7ls1:X2, 7ls2:X2, 6lu8:j, 5lzs:d, 5lzt:d, 5lzu:d, 5lzv:d, 5lzw:d, 5lzx:d, 5lzy:d, 5lzz:d, 7mdz:d, 6mtb:d, 6mtc:d, 6mtd:d, 6mte:d, 7nfx:d, 7nwg:d3, 7nwh:d, 7nwi:d, 7o7y:Bd, 7o7z:Bd, 7o80:Bd, 7o81:Bd, 7obr:d, 8ohd:Ld, 8oj0:Ld, 8oj5:Ld, 8oj8:Ld, 6ole:e, 6olf:e, 6olg:Ad, 6oli:e, 6olz:Ad, 6om0:e, 6om7:e, 7ow7:X, 7oya:d1, 7oyb:d1, 7oyc:d1, 7oyd:d, 8p2k:Bd, 6p5i:Ad, 6p5j:Ad, 6p5k:Ad, 6p5n:Ad, 8q7z:Bd, 8q87:Bd, 8qfd:d, 7qgg:e, 8qoi:Ld, 7qvp:Ld, 7qvp:Md, 7qwq:d, 7qwr:d, 7qws:d, 6qzp:Ld, 6r5q:d, 6r6g:d, 6r6p:d, 6r7q:d, 8rjb:d, 8rjc:d, 8rjd:d, 8scb:d, 6sgc:d2, 6swa:b, 5t2c:X, 6t59:d3, 7tm3:d, 7toq:AL31, 7tor:AL31, 7tut:d, 7ucj:d, 7uck:d, 4ug0:Ld, 4ujc:Bd, 4ujd:Ad, 4uje:Cd, 4v5z:Bx, 6w6l:e, 6xa1:Ld, 7xnx:Ld, 7xny:Ld, 8xsx:Ld, 8xsy:Ld, 8xsz:Ld, 6y0g:Ld, 8y0w:Ld, 8y0x:Ld, 6y2l:Ld, 6y57:Ld, 6y6x:Ld, 8yoo:Ld, 8yop:Ld, 6z6l:Ld, 6z6m:Ld, 6z6n:Ld, 7zjw:Lg, 7zjx:Lg, 6zm7:Ld, 6zme:Ld, 6zmi:Ld, 6zmo:Ld, 6zvk:u2
11 5t5h:h 150 103 0.2936 0.2133 0.3107 4.98e-08
12 8hfr:dG 110 112 0.3119 0.3091 0.3036 1.45e-07 8aaf:Q, 8agt:Q, 8agu:Q, 8agv:Q, 8agw:Q, 8agx:Q, 8agz:Q, 5apn:d, 5apo:d, 7azy:n, 7b7d:LZ, 8bip:Ld, 8bjq:Ld, 8bn3:O1, 8bqd:BC, 8bqx:BC, 7bt6:d, 7btb:d, 8ccs:P, 8cdl:P, 8cdr:P, 8ceh:P, 8cf5:P, 8cg8:P, 8cgn:P, 8civ:P, 8cku:P, 8cmj:P, 5dat:O1, 5dat:o1, 5dc3:O1, 5dc3:o1, 5dge:O1, 5dge:o1, 5dgf:O1, 5dgf:o1, 5dgv:O1, 5dgv:o1, 6elz:d, 6em5:d, 8eub:Ad, 8evp:Ad, 8evq:Ad, 8evr:Ad, 8evs:Ad, 8evt:Ad, 8ewb:Ad, 8ewc:Ad, 5fci:O1, 5fci:o1, 5fcj:O1, 5fcj:o1, 6ft6:d, 5gak:f, 6gq1:d, 6gqb:d, 6gqv:d, 5h4p:d, 6hd7:f, 6hhq:AE, 6hhq:DF, 5i4l:O1, 5i4l:o1, 6i7o:BC, 6i7o:YC, 3j6x:71, 3j6y:71, 3j77:81, 3j78:81, 3jct:d, 5jcs:d, 5juo:IA, 5jup:IA, 5jus:IA, 5jut:IA, 5juu:IA, 8k2d:Ld, 8k82:Ld, 5lyb:O1, 5lyb:o1, 5m1j:d5, 6m62:d, 5mc6:BC, 5mei:AE, 5mei:DF, 7mpi:Ad, 7mpj:Ad, 6n8j:d, 6n8k:d, 6n8l:d, 6n8m:q, 6n8n:q, 6n8o:q, 7n8b:Ad, 7nac:d, 5ndg:O1, 5ndg:o1, 5ndv:O1, 5ndv:o1, 5ndw:O1, 5ndw:o1, 7nrc:Lf, 7nrd:Lf, 5obm:O1, 5obm:o1, 7of1:d, 7oh3:d, 7ohq:d, 7ohr:d, 7ohv:d, 6oig:d, 5on6:AE, 5on6:DF, 7osa:eL31, 7osm:eL31, 8p8m:RD, 8p8n:RD, 8p8u:RD, 8pfr:RD, 6q8y:BC, 6qik:d, 6qt0:d, 6qtz:d, 7r7a:d, 6r84:f, 6r86:f, 6r87:f, 6ri5:d, 7rr5:Ld, 6rzz:d, 6s05:d, 6s47:Af, 6snt:am, 6sv4:BC, 6sv4:YC, 6sv4:ZC, 6t4q:Ld, 5t62:q, 5t6r:q, 6t7i:Ld, 6t7t:Ld, 6t83:dy, 6t83:O, 5tbw:AE, 5tbw:DF, 6tb3:BC, 5tga:O1, 5tga:o1, 5tgm:O1, 5tgm:o1, 6tnu:BC, 7too:AL31, 7top:AL31, 7u0h:d, 4u3m:O1, 4u3m:o1, 4u3n:O1, 4u3n:o1, 4u3u:O1, 4u3u:o1, 4u4n:O1, 4u4n:o1, 4u4o:O1, 4u4o:o1, 4u4q:O1, 4u4q:o1, 4u4r:O1, 4u4r:o1, 4u4u:O1, 4u4u:o1, 4u4y:O1, 4u4y:o1, 4u4z:O1, 4u4z:o1, 4u50:O1, 4u50:o1, 4u51:O1, 4u51:o1, 4u52:O1, 4u52:o1, 4u53:O1, 4u53:o1, 4u55:O1, 4u55:o1, 4u56:O1, 4u56:o1, 4u6f:O1, 4u6f:o1, 7ug6:d, 7uoo:d, 7uqb:d, 7uqz:d, 7v08:d, 4v4b:BW, 4v6i:Bg, 4v7h:BW, 4v7r:Ba, 4v7r:Da, 4v88:Bd, 4v88:Dd, 4v8t:d, 4v8y:Bd, 4v8z:Bd, 8v87:d, 4v91:d, 6woo:d, 6xiq:d, 6xir:d, 8y0u:Ld, 6ylg:d, 6ylh:d, 6ylx:d, 6yly:d, 7z34:d, 6z6j:Ld, 6z6k:Ld, 7zpq:Bc, 7zrs:Bc, 7zs5:Be, 7zuw:Bc, 7zux:Ec, 7zw0:Lg
13 5xxb:c 107 102 0.3486 0.3551 0.3725 3.67e-07
14 8br8:Le 100 100 0.2844 0.3100 0.3100 2.22e-06 8brm:Le, 8bsi:Le, 8bsj:Le, 8btd:Le, 8btr:Le, 8fru:d, 7pwg:d, 7pwo:d2
15 8c3a:AE 110 111 0.2844 0.2818 0.2793 2.49e-06 8c3a:BY, 8cq7:AE, 8cq7:BY, 8cqw:AE, 8cqw:BY, 8cre:AE, 8cre:BY, 8oeq:AE, 8oeq:BY, 7pzy:AE, 7q08:AE, 7q0f:AE, 7q0p:AE, 7q0r:AE, 8q5i:AE
16 8etc:d 102 60 0.2110 0.2255 0.3833 2.09e-05 8esq:d, 8esr:d, 8etg:d, 8eti:d, 8etj:d, 8eug:d, 8eui:d
17 4v6u:Ba 90 75 0.2202 0.2667 0.3200 2.21e-05 4v4n:Aa
18 5it7:dd 106 100 0.3028 0.3113 0.3300 1.26e-04 6uz7:Bd
19 4v6w:Cd 111 101 0.2752 0.2703 0.2970 1.83e-04 6xu6:Cd, 6xu7:Cd, 6xu8:Cd
20 7z3n:Ld 119 68 0.2110 0.1933 0.3382 3.10e-04 8i9v:Ld, 8i9w:Ld, 8i9x:Ld, 8i9y:Ld, 8i9z:Ld, 8ia0:Ld, 7olc:Ld, 7old:Ld, 8oo0:Ld, 8pv1:Ld, 8pv2:Ld, 8pv3:Ld, 8pv4:Ld, 8pv5:Ld, 8pv6:Ld, 8pv7:Ld, 8pv8:Ld, 8pvk:Ld, 8pvl:Ld, 7z3o:Ld
21 4v9f:X 90 42 0.1284 0.1556 0.3333 5.02e-04 3cc2:X, 3cc4:X, 3cc7:X, 3cce:X, 3ccj:X, 3ccl:X, 3ccm:X, 3ccq:X, 3ccr:X, 3ccs:X, 3ccu:X, 3ccv:X, 3cd6:X, 3cma:X, 3cme:X, 3cpw:W, 3cxc:W, 3g4s:X, 3g6e:X, 3g71:X, 3i55:X, 3i56:X, 1jj2:W, 1k73:Y, 1k8a:Y, 1k9m:Y, 1kc8:Y, 1kd1:Y, 1kqs:W, 1m1k:Y, 1m90:Y, 1n8r:Y, 1nji:Y, 2otj:X, 2otl:X, 3ow2:W, 1q7y:Y, 1q81:Y, 1q82:Y, 1q86:Y, 2qa4:X, 2qex:X, 1qvf:W, 1qvg:W, 1s72:X, 1vq4:X, 1vq5:X, 1vq6:X, 1vq7:X, 1vq8:X, 1vq9:X, 1vqk:X, 1vql:X, 1vqm:X, 1vqn:X, 1vqo:X, 1vqp:X, 1w2b:W, 1yhq:X, 1yi2:X, 1yij:X, 1yit:X, 1yj9:X, 1yjn:X, 1yjw:X
22 9bh5:Cd 105 78 0.2385 0.2476 0.3333 7.72e-04 9cai:Cd
23 7nad:d 72 73 0.1835 0.2778 0.2740 8.00e-04 7r72:d
24 6skf:Bc 89 75 0.2294 0.2809 0.3333 0.002 6skg:Bc, 6th6:Bc
25 7r81:f1 104 61 0.1927 0.2019 0.3443 0.007
26 5xy3:d 99 100 0.2752 0.3030 0.3000 0.13
27 7qiw:f 110 105 0.2569 0.2545 0.2667 0.26 8azw:Q, 8b2l:Q3, 2go5:6, 2j37:6, 7qiz:f
28 3qfq:B 120 78 0.2110 0.1917 0.2949 0.90 3qfq:A, 3qfq:E
29 7t92:A 298 61 0.1284 0.0470 0.2295 1.0
30 3b7r:L 610 31 0.1101 0.0197 0.3871 1.8 5aen:A, 7auz:A, 7av0:A, 7av1:A, 7av2:A, 8ava:A, 8awh:A, 3b7s:A, 3b7t:A, 3b7u:X, 5bpp:A, 3cho:A, 3chp:A, 3chq:A, 3chr:A, 3chs:A, 4dpr:A, 6enb:A, 6enc:A, 6end:A, 3fh5:A, 3fh7:A, 3fh8:A, 3fhe:A, 3fts:A, 3ftu:A, 3ftv:A, 3ftw:A, 3ftx:A, 3fty:A, 3ftz:A, 3fu0:A, 3fu3:A, 3fu5:A, 3fu6:A, 3fud:A, 3fue:A, 3fuf:A, 3fuh:A, 3fui:A, 3fuj:A, 3fuk:A, 3ful:A, 3fum:A, 3fun:A, 5fwq:A, 1gw6:A, 1h19:A, 1hs6:A, 7kze:A, 7kze:B, 7kze:C, 4l2l:A, 7llq:A, 7llq:B, 7llq:C, 4mkt:A, 4ms6:A, 5n3w:A, 5ni2:A, 5ni4:A, 5ni4:B, 5ni4:C, 5ni6:A, 5nia:A, 5nid:A, 5nie:A, 5nie:B, 5nie:C, 6o5h:A, 6o5h:B, 6o5h:C, 8qow:A, 8qpn:A, 8qq4:A, 2r59:A, 4r7l:A, 4rsy:A, 4rvb:A, 8rx3:A, 8rx7:A, 8rx9:A, 1sqm:A, 8twx:A, 8twx:B, 8twx:C, 3u9w:A, 2vj8:A
31 2zbu:A 263 45 0.1193 0.0494 0.2889 2.0 2zbu:B, 2zbu:C, 2zbu:D, 2zbv:A, 2zbv:B, 2zbv:C
32 8wey:5 183 47 0.1193 0.0710 0.2766 2.9 7blz:2, 6fos:2, 6fos:3, 8wey:2, 5zgb:2, 5zgb:5, 5zgh:2
33 6ayi:A 183 52 0.1009 0.0601 0.2115 3.0 6ayi:B, 6ayi:C, 6ayi:D
34 6g0b:A 393 18 0.0826 0.0229 0.5000 3.2 6g09:A, 6g0n:A
35 7bbr:A 310 60 0.1560 0.0548 0.2833 6.4 7bcn:A, 7bco:A, 7bco:B, 7bcp:A, 7bcr:A
36 4v3p:Lg 120 103 0.2477 0.2250 0.2621 8.4 8ip8:SA, 8ipa:SA, 8ipb:SA, 8jiv:Cd, 4v7e:Cd
37 7l01:B 385 30 0.0917 0.0260 0.3333 9.8 5boo:A, 5boo:B, 4cq8:A, 4cq8:B, 4cq9:A, 4cq9:B, 4cqa:A, 4cqa:B, 5del:A, 6e0b:A, 5fi8:A, 6gjg:A, 6gjg:B, 6i4b:A, 6i4b:B, 6i55:A, 6i55:B, 3i65:A, 3i68:A, 3i6r:A, 7kyk:A, 7kyk:B, 7kyk:C, 7kyk:D, 7kyv:A, 7kyy:A, 7kyy:B, 7kyy:C, 7kyy:D, 7kz4:A, 7kz4:B, 7kzy:A, 7kzy:B, 7l01:A, 7l0k:A, 7l0k:B, 3o8a:A, 4orm:A, 4rx0:A, 7s87:A, 7s87:B, 3sfk:A, 5tbo:A, 1tv5:A, 6vtn:A, 6vty:A, 6vty:B, 6vty:C, 6vty:D, 7wyf:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218