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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGT
GVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVI
DEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKR
FLLLFTFLKKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIP
EVDWIVQYDPPDDPKEYIHRVGRTRGHALLILRPEELGFLRYLKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKS
AQEAYKSYIRAYDSHSLKQIFNVNNLNLPQVALSFGFKVPPFVDL

The query sequence (length=445) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8fky:SW 448 448 1.0000 0.9933 0.9933 0.0 8fkp:SW, 8fkq:SW, 8fkr:SW, 8fks:SW, 8fkt:SW, 8fku:SW, 8fkv:SW, 8fkw:SW, 8fkx:SW, 3ly5:A
2 8i9z:CE 465 439 0.6584 0.6301 0.6674 0.0 8i9p:CE, 8i9r:CE, 8i9t:CE, 8i9v:CE, 8i9w:CE, 8i9x:CE, 8i9y:CE, 8ia0:CE
3 5z3g:Y 438 435 0.6315 0.6416 0.6460 0.0 6c0f:p, 6cb1:p, 8e5t:p, 7nac:D, 7ohr:D, 7ohs:D, 7ohv:D, 7ohw:D, 7ohx:D, 7r6q:D, 7r7a:D, 8v87:D
4 8esq:D 427 433 0.6427 0.6698 0.6605 0.0 8esr:D, 8eth:D, 8eup:D, 8euy:D, 8ev3:D
5 8v83:D 423 433 0.6090 0.6407 0.6259 0.0 6elz:D, 8v84:D
6 8eti:D 391 433 0.5910 0.6726 0.6074 0.0
7 8ia0:CW 540 467 0.3506 0.2889 0.3340 1.21e-65 8i9z:CW
8 2pl3:A 232 205 0.2427 0.4655 0.5268 5.68e-64
9 7nac:x 539 445 0.3213 0.2653 0.3213 5.42e-62 7nad:x, 7r72:x, 7r7a:x
10 3i5x:A 509 481 0.3506 0.3065 0.3243 7.37e-60 4db2:C, 4db2:A, 4db2:B, 4db2:D, 4db4:A, 3i5y:A, 3i61:A, 3i62:A, 3sqw:A, 3sqx:A, 4tyn:A, 4tyw:A, 4tyy:A, 4tz0:A, 4tz6:A
11 7pmq:C 458 360 0.2876 0.2795 0.3556 1.50e-56 7pli:A, 7pli:B, 7pli:J, 7pli:E, 7pli:F, 7pli:I, 7pmm:A, 7pmm:B, 7pmq:D, 7pmq:A, 7pmq:B
12 8i9v:Cb 642 363 0.2787 0.1931 0.3416 8.31e-53 8i9t:Cb, 8i9w:Cb, 8i9x:Cb
13 8arp:C 445 329 0.2517 0.2517 0.3404 2.45e-51 8arp:A, 8arp:B, 8arp:D, 8arp:E, 8arp:F
14 8fkv:NI 647 448 0.3213 0.2210 0.3192 9.43e-51 8fkt:NI, 8fku:NI, 8fkw:NI, 8fkx:NI, 8fky:NI
15 6l5n:A 377 342 0.2629 0.3103 0.3421 2.39e-50 6l5m:A, 6l5m:B, 6l5m:C, 6l5m:D, 6l5m:E, 6l5n:B, 6l5o:A
16 6uv1:A 438 353 0.2517 0.2557 0.3173 3.12e-50 6uv1:B, 6uv2:A, 6uv3:A, 6uv4:A
17 4kbf:A 365 328 0.2584 0.3151 0.3506 8.15e-49 2gxq:A, 2gxs:A, 2gxs:B, 2gxu:A, 3mwk:B, 3mwl:B, 3nbf:A, 3nbf:B, 3nbf:C, 3nbf:D
18 8v87:3 656 368 0.2742 0.1860 0.3315 4.23e-48 8v84:3
19 7liu:A 442 338 0.2607 0.2624 0.3432 5.33e-48 6cz5:A, 5e7j:A, 5e7m:A, 2i4i:A, 7liu:B, 4px9:A, 4px9:B, 4px9:C, 4pxa:A, 8ssw:A, 8ssw:B
20 4d26:A 430 358 0.2764 0.2860 0.3436 5.80e-48 4d25:A
21 3ex7:C 392 362 0.2427 0.2755 0.2983 6.69e-48 8c6j:7, 3ex7:H, 9fmd:7, 2hyi:C, 2hyi:I, 8i0w:u, 6icz:u, 2j0q:A, 2j0q:B, 2j0s:A, 2j0u:A, 6qdv:7, 2xb2:A, 2xb2:X, 5xjc:u, 5yzg:u, 7znj:A, 7znj:a, 7znj:F, 7znj:f, 7znj:K, 7znj:k
22 2db3:A 420 358 0.2584 0.2738 0.3212 1.90e-47 2db3:B, 2db3:C, 2db3:D
23 4bru:A 375 327 0.2315 0.2747 0.3150 1.77e-46
24 4ct4:B 378 327 0.2225 0.2619 0.3028 7.31e-45 5anr:B, 4ct4:D, 1vec:A, 2wax:C, 2way:A
25 5dtu:A 404 367 0.2652 0.2921 0.3215 1.13e-44
26 2vso:A 366 357 0.2584 0.3142 0.3221 1.38e-44 1fuk:A, 2vso:B, 2vsx:A, 2vsx:B
27 6xki:A 378 328 0.2315 0.2725 0.3140 1.71e-42 5zbz:A, 5zc9:A
28 8y6o:I 597 393 0.2787 0.2077 0.3155 2.91e-42 8qp8:G, 6qw6:5X, 6qx9:5X, 8r08:G
29 4ljy:A 451 355 0.2337 0.2306 0.2930 7.01e-42 7oqb:p, 7oqe:p
30 6o5f:A 417 330 0.2472 0.2638 0.3333 3.05e-41 6o5f:B
31 3ber:A 220 195 0.1820 0.3682 0.4154 6.70e-41
32 8enk:B 381 352 0.2292 0.2677 0.2898 2.07e-39 8enk:A, 1xtj:A, 7znk:P, 7znk:p
33 5sup:B 383 358 0.2337 0.2715 0.2905 4.22e-37 5sup:A, 5sup:C, 5suq:A, 5suq:C
34 4w7s:B 448 359 0.2584 0.2567 0.3203 7.73e-36
35 6aic:A 202 196 0.1640 0.3614 0.3724 1.23e-33
36 3fe2:A 234 193 0.1640 0.3120 0.3782 3.16e-33 3fe2:B
37 5h1y:B 245 210 0.1708 0.3102 0.3619 1.48e-32 5h1y:A
38 5elx:A 391 340 0.2360 0.2685 0.3088 6.49e-32 3peu:A, 3pev:A, 3pew:A, 3pey:A, 3rrm:A, 3rrn:A
39 5gju:A 199 215 0.1775 0.3970 0.3674 2.47e-28
40 6b4i:F 426 345 0.2067 0.2160 0.2667 4.97e-27 6b4i:E, 6b4j:E, 6b4j:F, 6b4k:A, 6b4k:B, 3ews:A, 3ews:B, 3fht:A, 3fht:B, 3fmo:B, 3fmp:B, 3fmp:D, 3g0h:A
41 3iuy:A 213 201 0.1573 0.3286 0.3483 5.42e-26 3iuy:B
42 7oi6:x 374 356 0.2337 0.2781 0.2921 2.69e-24
43 3dkp:A 240 201 0.1618 0.3000 0.3582 3.63e-23
44 8tbx:A 458 184 0.1438 0.1397 0.3478 6.01e-21
45 8tbx:A 458 79 0.0629 0.0611 0.3544 1.34e-09
46 7am2:BW 447 371 0.2045 0.2036 0.2453 2.68e-17
47 3b7g:A 205 200 0.1438 0.3122 0.3200 1.90e-16 3b7g:B, 2oxc:A, 2oxc:B
48 6crm:A 512 391 0.2067 0.1797 0.2353 1.42e-11 4tmu:A
49 6s8r:A 167 121 0.0697 0.1856 0.2562 3.29e-10
50 1oyw:A 516 399 0.2045 0.1764 0.2281 2.33e-09 1oyy:A
51 6yxy:EB 663 204 0.1146 0.0769 0.2500 9.27e-08 7aoi:XB, 6yxx:EB
52 6yxy:EB 663 93 0.0674 0.0452 0.3226 1.45e-05 7aoi:XB, 6yxx:EB
53 5v9x:A 772 358 0.1865 0.1075 0.2318 2.96e-07
54 4q47:A 513 330 0.1685 0.1462 0.2273 4.75e-07 4q47:B, 4q48:A, 4q48:B
55 2rb4:A 164 140 0.0787 0.2134 0.2500 1.44e-06
56 5lst:A 617 366 0.1798 0.1297 0.2186 1.35e-05
57 7aud:A 522 342 0.1730 0.1475 0.2251 1.70e-04 7aud:E, 7aud:B, 7aud:C, 7aud:D, 7aud:F
58 4cgz:A 629 342 0.1730 0.1224 0.2251 2.46e-04 4cdg:A, 4cdg:B, 4o3m:A
59 6acx:A 1175 381 0.1843 0.0698 0.2152 3.13e-04 6acx:B
60 7auc:A 493 331 0.1663 0.1501 0.2236 7.79e-04
61 1gm5:A 729 356 0.1708 0.1043 0.2135 8.92e-04
62 6uxw:A 778 160 0.0831 0.0476 0.2313 0.003 7egp:A, 6iy2:O, 6iy3:O, 6uxv:A, 5x0x:O, 5x0y:O, 5z3l:O, 5z3o:O, 5z3u:O, 5z3v:O
63 8dfv:A 1664 53 0.0382 0.0102 0.3208 0.003
64 8dg5:A 1635 53 0.0382 0.0104 0.3208 0.003 8dg7:A
65 2zja:A 700 182 0.1034 0.0657 0.2527 0.003 2zj5:A
66 5zal:A 1314 85 0.0517 0.0175 0.2706 0.005 2eb1:A, 2eb1:B, 2eb1:C, 4ngd:A, 5zam:A
67 2p6r:A 683 131 0.0831 0.0542 0.2824 0.005
68 7yym:A 1281 56 0.0360 0.0125 0.2857 0.014 4ngb:A, 4ngc:A, 4ngg:A, 4nh3:A, 4nh5:A, 4nh6:A, 7yyn:A, 7zpi:A, 7zpj:A, 7zpk:A
69 8sp4:A 859 181 0.0989 0.0512 0.2431 0.015 8spg:A
70 8dga:A 1629 49 0.0360 0.0098 0.3265 0.017
71 4a4z:A 874 161 0.0876 0.0446 0.2422 0.018
72 8t5s:A 693 62 0.0427 0.0274 0.3065 0.018
73 8t5s:A 693 105 0.0674 0.0433 0.2857 0.042
74 8q9t:A 1075 161 0.0899 0.0372 0.2484 0.023
75 5mc6:h 1121 161 0.0899 0.0357 0.2484 0.025 4a4k:A, 4a4k:C, 4a4k:E, 4a4k:G, 4a4k:I
76 6yhr:A 541 366 0.1663 0.1368 0.2022 0.030 3aaf:A, 3aaf:B, 7gqs:A, 7gqt:A, 7gqu:A, 8pfl:A, 8pfo:A, 8pfp:A, 8yle:A
77 4a36:A 523 114 0.0652 0.0554 0.2544 0.25 4a36:B
78 6vz4:K 616 98 0.0517 0.0373 0.2347 0.28 6kw3:Y, 6kw4:Y, 6kw5:Q
79 8vxa:A 1139 146 0.0787 0.0307 0.2397 0.36 8vxc:A
80 6tda:S 783 98 0.0517 0.0294 0.2347 0.38
81 8vxy:B 1161 146 0.0787 0.0301 0.2397 0.40
82 5jbj:A 627 61 0.0404 0.0287 0.2951 0.51
83 6fwr:A 699 26 0.0315 0.0200 0.5385 0.55 6fws:A, 6fws:B
84 5jb2:A 670 60 0.0404 0.0269 0.3000 0.60 5jaj:A, 5jbg:A
85 7v6c:A 1540 123 0.0674 0.0195 0.2439 0.62
86 6bge:A 323 140 0.0674 0.0929 0.2143 0.76 6bge:B, 1g6o:A, 1g6o:B, 1nly:A, 1nly:B
87 7eld:A 1137 76 0.0449 0.0176 0.2632 0.81 7ele:A
88 6aje:A 378 76 0.0517 0.0608 0.3026 0.96 6aj5:A, 6aj5:B, 6aj5:C, 6aj5:D, 6aje:B, 6aje:C, 6aje:D
89 7jl0:A 662 58 0.0360 0.0242 0.2759 1.2 7jl2:A, 7jl2:C, 7jl2:E
90 7jl0:A 662 132 0.0742 0.0498 0.2500 1.7 7jl2:A, 7jl2:C, 7jl2:E
91 6m6a:M 459 287 0.1393 0.1351 0.2160 1.6 6m6b:M
92 3tbk:A 524 111 0.0584 0.0496 0.2342 1.9
93 5ipf:A 201 49 0.0360 0.0796 0.3265 2.1 5ipf:B, 5ipf:C, 5ipf:D
94 8h10:A 1026 135 0.0787 0.0341 0.2593 2.4 8h0y:B, 8h0z:A, 8h10:B, 8h10:C, 7zh1:A, 7zh1:B, 7zh1:C, 7zh2:A, 7zh2:B, 7zh2:C
95 8h0z:B 1045 85 0.0584 0.0249 0.3059 2.4 8h0x:A, 8h0x:B, 8h0x:C, 8h0y:A, 8h0y:C, 8h0z:C, 8h14:B, 8h14:C, 8h14:A
96 8hf0:A 1561 48 0.0270 0.0077 0.2500 2.5 8hf0:D, 8hf1:A, 8hf1:D, 8hf1:G, 7w0a:A, 7w0a:E, 7w0c:A, 7w0d:A, 7w0e:A, 7w0f:A
97 7w0b:A 1586 48 0.0270 0.0076 0.2500 2.5 7w0d:F
98 7cn8:A 1125 88 0.0562 0.0222 0.2841 2.7 7cn8:B, 7cn8:C, 7ek6:A, 7xu0:A, 7xu1:C, 7xu1:B, 7xu2:A, 7xu2:C, 7xu2:B, 7xu4:A, 7xu4:C, 7xu4:B
99 5jc7:A 641 58 0.0360 0.0250 0.2759 3.5
100 1frr:A 95 40 0.0337 0.1579 0.3750 3.5 1frr:B
101 8ps2:G 2036 112 0.0584 0.0128 0.2321 3.7 3hmj:G, 3hmj:H, 3hmj:I, 8prv:G, 8prw:G, 8prw:J, 8prw:I, 8prw:H, 8prw:K, 8prw:L, 8ps1:G, 8ps9:G, 8psa:G, 8psf:G, 8psg:G, 8psj:G, 8psk:G, 8psl:G, 8psm:G, 8psp:G, 6ql5:I, 6ql5:G, 6ql5:H, 6ql5:L, 6ql5:J, 6ql5:K, 6ql6:G, 6ql6:H, 6ql6:I, 6ql6:J, 6ql6:K, 6ql6:L, 6ql9:G, 6ql9:H, 6ql9:I, 6ql9:J, 6ql9:K, 6ql9:L, 6ta1:G, 6ta1:C, 6ta1:E, 6ta1:L, 6ta1:H, 6ta1:J, 6u5t:G, 6u5u:G, 2uv8:G, 2uv8:H, 2uv8:I, 2vkz:G, 2vkz:H, 2vkz:I
102 6t4h:A 771 128 0.0764 0.0441 0.2656 4.1
103 5jc3:A 668 58 0.0360 0.0240 0.2759 4.2 5jc3:B, 5jc7:B, 5jcf:A, 5jcf:B, 5jch:A, 5jch:B
104 3crw:1 485 259 0.1281 0.1175 0.2201 4.2
105 7bkp:A 689 58 0.0337 0.0218 0.2586 5.0 6g19:A, 6gjz:A, 6gkh:A, 6gkm:A, 6h66:A, 7nic:A, 7niq:B
106 6c7n:A 553 42 0.0270 0.0217 0.2857 7.2 6c7n:B, 6c7n:C
107 6c7n:D 389 42 0.0270 0.0308 0.2857 9.7
108 1z63:A 468 68 0.0337 0.0321 0.2206 10.0 1z63:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218