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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTF
LRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQ
FGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATL
KPR

The query sequence (length=243) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2b76:B 243 243 1.0000 1.0000 1.0000 0.0 6awf:B, 6awf:F, 2b76:N, 3cir:B, 3cir:N, 1kf6:B, 1kf6:N, 1kfy:B, 1kfy:N, 4kx6:B, 4kx6:N, 1l0v:B, 1l0v:N, 3p4p:B, 3p4p:N, 3p4q:B, 3p4q:N, 3p4r:B, 3p4r:N, 3p4s:B, 3p4s:N, 5vpn:B, 5vpn:F
2 6lum:K 247 232 0.3416 0.3360 0.3578 1.65e-47 6lum:B, 6lum:Q
3 2acz:B 238 232 0.3621 0.3697 0.3793 2.33e-43 7jz2:B, 7jz2:F, 7jz2:J, 1nek:B, 1nen:B, 2wdq:B, 2wdq:F, 2wdq:J, 2wdr:B, 2wdr:F, 2wdr:J, 2wdv:B, 2wdv:F, 2wdv:J, 2wp9:B, 2wp9:F, 2wp9:J, 2ws3:B, 2ws3:F, 2ws3:J, 2wu2:B, 2wu2:F, 2wu2:J, 2wu5:B, 2wu5:F, 2wu5:J, 6wu6:B, 6wu6:F, 6wu6:J
4 8b6g:CB 285 243 0.3457 0.2947 0.3457 1.29e-35 8bqs:CB, 8gym:sb, 8gym:SB, 8gzu:sb, 8gzu:SB
5 4ysx:F 252 231 0.3086 0.2976 0.3247 8.13e-35 5c2t:B, 5c2t:F, 5c3j:B, 5c3j:F, 3vr8:B, 3vr8:F, 3vr9:B, 3vr9:F, 3vra:B, 3vra:F, 3vrb:B, 3vrb:F, 4ysx:B, 4ysy:B, 4ysy:F, 4ysz:B, 4ysz:F, 4yt0:B, 4yt0:F, 4ytm:B, 4ytm:F, 4ytn:B, 4ytn:F
6 3sfe:B 240 227 0.2881 0.2917 0.3084 6.16e-33 3abv:B, 3ae1:B, 3ae2:B, 3ae3:B, 3ae4:B, 3ae5:B, 3ae6:B, 3ae7:B, 3ae8:B, 3ae9:B, 3aea:B, 3aeb:B, 3aec:B, 3aed:B, 3aee:B, 3aef:B, 3aeg:B, 7kcm:C, 3sfd:B, 4ytp:B, 4yxd:B, 1zoy:B, 1zp0:B
7 1yq3:B 242 228 0.3045 0.3058 0.3246 1.55e-32 2fbw:B, 2fbw:O, 8gs8:B, 2h88:B, 2h88:O, 2h89:B, 6myo:B, 6myp:B, 6myq:B, 6myr:B, 6mys:B, 6myt:B, 6myu:B, 2wqy:B, 2wqy:O, 1yq4:B
8 2bs2:B 239 220 0.2634 0.2678 0.2909 9.74e-31 2bs2:E, 2bs3:B, 2bs3:E, 2bs4:B, 2bs4:E, 1e7p:B, 1e7p:E, 1e7p:H, 1e7p:K, 1qlb:B, 1qlb:E
9 5xmj:B 240 220 0.2593 0.2625 0.2864 1.06e-24 5xmj:F, 5xmj:J, 5xmj:N
10 7d6v:B 239 207 0.2305 0.2343 0.2705 1.63e-19 7d6x:B
11 4hea:9 180 68 0.0947 0.1278 0.3382 8.48e-04 2fug:9, 2fug:G, 2fug:P, 2fug:Y, 4hea:O, 6i0d:9, 6i0d:O, 6i1p:9, 6i1p:O, 3i9v:9, 3i9v:G, 3iam:9, 3iam:G, 3ias:9, 3ias:G, 3ias:P, 3ias:Y, 3m9s:9, 3m9s:G, 6q8o:9, 6q8o:O, 6q8w:9, 6q8w:O, 6q8x:9, 6q8x:O, 6y11:9, 6y11:O, 2ybb:8, 6ziy:9, 6zjl:9, 6zjn:9, 6zjy:9
12 6cin:B 1169 98 0.1029 0.0214 0.2551 0.003 6cin:A, 6cin:C, 6cin:D, 6cin:E, 6cin:F, 6cio:A, 6cio:B, 6cio:C, 6cio:D, 6cio:E, 6cio:F, 6cip:A, 6cip:B, 6cip:C, 6cip:D, 6cip:E, 6cip:F, 6ciq:A, 6ciq:B, 6ciq:C
13 7zc6:C 435 97 0.1152 0.0644 0.2887 0.019
14 8rbq:C 477 71 0.0947 0.0482 0.3239 0.048 8ahx:C, 8rb8:C, 8rb9:C, 8rbm:C
15 1sb3:C 161 87 0.1029 0.1553 0.2874 0.051 1rm6:C, 1rm6:F, 1sb3:F
16 1b0p:A 1231 113 0.1193 0.0236 0.2566 0.15 1b0p:B, 2c3m:A, 2c3m:B, 2c3o:A, 2c3o:B, 2c3p:A, 2c3p:B, 2c3u:A, 2c3u:B, 2c3y:A, 2c3y:B, 2c42:A, 2c42:B, 1kek:A, 1kek:B, 2pda:A, 2pda:B, 2uza:A, 2uza:B
17 7plm:A 1177 106 0.0988 0.0204 0.2264 0.19 7plm:B
18 7arc:I 199 68 0.0823 0.1005 0.2941 0.32 7ard:I
19 8e73:S8 181 68 0.0782 0.1050 0.2794 0.84 7a23:D, 7a24:D, 7aqr:I, 7ar7:I, 7ar8:I, 7arb:I, 8bee:I, 8bpx:I, 8bq5:I, 8bq6:I, 6x89:S8
20 5odc:C 184 81 0.0823 0.1087 0.2469 1.00 5odc:I, 5odh:C, 5odh:I, 5odi:C, 5odi:I, 5odq:C, 5odq:I, 5odr:C, 5odr:I
21 8ips:A 573 62 0.0741 0.0314 0.2903 1.5 8ipt:C, 8ipt:D, 7zda:C, 7zdb:C, 7zdc:C, 7zdf:C, 7zdg:C, 7zdk:C, 7zdl:C, 7zdt:C, 7zdu:C, 7zdw:C, 7ze5:C, 7zec:C
22 5y6q:A 157 86 0.0988 0.1529 0.2791 1.5
23 1t3q:A 162 88 0.0658 0.0988 0.1818 1.6 1t3q:D
24 7p63:I 180 25 0.0576 0.0778 0.5600 1.6 7awt:I, 7nyr:I, 7nyu:I, 7nyv:I, 7nz1:I, 7p61:I, 7p62:I, 7p64:I, 7p69:I, 7p7c:I, 7p7e:I, 7p7j:I, 7p7k:I, 7p7l:I, 7p7m:I, 7z7r:I, 7z7s:I, 7z7t:I, 7z7v:I, 7z80:I, 7z83:I, 7z84:I, 7zc5:I, 7zci:I
25 7p63:I 180 68 0.0782 0.1056 0.2794 3.4 7awt:I, 7nyr:I, 7nyu:I, 7nyv:I, 7nz1:I, 7p61:I, 7p62:I, 7p64:I, 7p69:I, 7p7c:I, 7p7e:I, 7p7j:I, 7p7k:I, 7p7l:I, 7p7m:I, 7z7r:I, 7z7s:I, 7z7t:I, 7z7v:I, 7z80:I, 7z83:I, 7z84:I, 7zc5:I, 7zci:I
26 3kez:B 448 55 0.0741 0.0402 0.3273 1.7 3kez:A
27 8e9i:I 166 79 0.1029 0.1506 0.3165 1.7 8e9g:I, 8e9h:I
28 8e9i:I 166 46 0.0617 0.0904 0.3261 5.2 8e9g:I, 8e9h:I
29 8qby:I 159 68 0.0823 0.1258 0.2941 2.0
30 7z0s:F 164 89 0.1029 0.1524 0.2809 2.1 7z0t:F
31 7b0n:I 191 68 0.0823 0.1047 0.2941 2.2 6gcs:I, 7o6y:I, 7o71:I, 6rfq:I, 6rfr:I, 6rfs:I, 6y79:I, 6yj4:I
32 7bkb:E 411 98 0.1029 0.0608 0.2551 2.2 7bkb:e, 7bkc:E, 7bkc:e, 7bkd:E, 7bke:E
33 7ueb:B 114 29 0.0576 0.1228 0.4828 2.4 7uea:B
34 8b9z:I 186 68 0.0782 0.1022 0.2794 2.7 8ba0:I, 8esw:S8, 8esz:S8
35 7zm7:I 185 68 0.0782 0.1027 0.2794 2.8 7zmb:I, 7zmg:I
36 6h8k:I 137 68 0.0741 0.1314 0.2647 3.4
37 6tmf:d 582 98 0.1111 0.0464 0.2755 4.0 3ozx:A, 3ozx:B
38 7wfg:I 160 104 0.1029 0.1562 0.2404 4.3 7wg5:I
39 6qgr:G 253 21 0.0453 0.0435 0.5238 4.4 6qgt:G, 6qii:G
40 7vi6:A 342 44 0.0617 0.0439 0.3409 5.1 7vi6:B, 7vi7:A, 7vi7:B
41 8b6f:AL 218 68 0.0782 0.0872 0.2794 5.6 8bqs:AL, 8gym:s8, 8gym:S8, 8gzu:s8, 8gzu:S8, 7tgh:S8
42 7q5y:D 197 90 0.0905 0.1117 0.2444 5.7 7q5y:J, 7q5y:P, 7q5y:V
43 5g5g:A 175 54 0.0700 0.0971 0.3148 5.9 5g5h:A
44 5t61:L 348 105 0.1070 0.0747 0.2476 6.4 5t5i:F, 5t5i:N, 5t5m:F, 5t61:F, 5t61:R, 5t61:X, 5t61:d, 5t61:j, 5t61:p, 5t61:v
45 1dur:A 55 53 0.0617 0.2727 0.2830 7.2
46 4q2d:A 927 49 0.0658 0.0173 0.3265 7.6
47 7ak5:I 178 68 0.0782 0.1067 0.2794 8.5 7ak6:I, 7b93:I, 8c2s:I, 8ca3:I, 8ca5:I, 7dgq:E, 7dgr:E, 7dgs:E, 7dgz:E, 7dh0:E, 7dkf:E2, 6g2j:I, 6g72:I, 5gpn:b, 5gup:H, 8iao:I, 8iap:I, 8ib4:I, 8ib5:I, 8ib9:I, 8iba:I, 8ibd:I, 8ibe:I, 8ic2:I, 8ic3:I, 5lc5:I, 5ldw:I, 5ldx:I, 5lnk:9, 5o31:I, 8olt:I, 8om1:I, 7psa:I, 8pw5:9, 8pw6:9, 8pw7:9, 8q0a:I, 8q0f:I, 8q0j:I, 8q0m:I, 8q0o:I, 8q0q:I, 8q1p:I, 8q1u:I, 8q1y:I, 8q25:I, 8q45:I, 8q46:I, 8q47:I, 8q48:I, 8q49:I, 8q4a:I, 6q9d:S8, 6qa9:S8, 6qbx:S8, 6qc2:S8, 6qc3:S8, 6qc4:S8, 6qc5:S8, 6qc6:S8, 6qc7:S8, 6qc8:S8, 6qc9:S8, 6qca:S8, 6qcf:S8, 7qsd:I, 7qsk:I, 7qsl:I, 7qsm:I, 7qsn:I, 7qso:I, 7r41:I, 7r42:I, 7r43:I, 7r44:I, 7r45:I, 7r46:I, 7r47:I, 7r48:I, 7r4c:I, 7r4d:I, 7r4f:I, 7r4g:I, 8rgp:9, 8rgq:9, 8rgr:9, 8rgt:9, 8ud1:1I, 8ueo:1I, 8uep:1I, 8ueq:1I, 8uer:1I, 8ues:1I, 8uet:1I, 8ueu:1I, 8uev:1I, 8uew:1I, 8uex:1I, 8uey:1I, 8uez:1I, 8ugh:1I, 8ugi:1I, 8ugj:1I, 8ugn:1I, 8ugn:5I, 8ugp:1I, 8ugr:1I, 8ugr:5I, 7v2c:B, 7v2d:B, 7v2e:B, 7v2f:B, 7v2h:B, 7v2k:B, 7v2r:B, 7v30:B, 7v31:B, 7v32:B, 7v33:B, 7v3m:B, 7vb7:B, 7vbn:B, 7vbz:B, 7vwj:B, 7vxp:B, 7vxu:B, 7vy8:B, 7vya:B, 7vyf:B, 7vyh:B, 7vyn:B, 7vz1:B, 7vzv:B, 7vzw:B, 7w00:B, 7w0h:B, 7w0r:B, 7w0y:B, 7w1o:B, 7w1p:B, 7w1t:B, 7w1u:B, 7w1v:B, 7w1z:B, 7w20:B, 7w2k:B, 7w2l:B, 7w2r:B, 7w2u:B, 7w2y:B, 7w31:B, 7w32:B, 7w35:B, 7w4c:B, 7w4d:B, 7w4e:B, 7w4f:B, 7w4g:B, 7w4j:B, 7w4k:B, 7w4l:B, 7w4m:B, 7w4n:B, 7w4q:B, 5xtb:B, 5xtd:B, 5xth:B, 5xti:B, 5xti:BB, 7zd6:9, 7zdh:9, 7zdj:9, 7zdm:9, 7zdp:9, 7zeb:9, 6zk9:9, 6zkc:9, 6zkd:9, 6zke:9, 6zkf:9, 6zkg:9, 6zkh:9, 6zki:9, 6zkj:9, 6zkk:9, 6zkl:9, 6zkm:9, 6zkn:9, 6zko:9, 6zkp:9, 6zkq:9, 6zkr:9, 6zks:9, 6zkt:9, 6zku:9, 6zkv:9, 6zr2:I, 6ztq:I
48 7dqx:C 160 57 0.0617 0.0938 0.2632 9.0 7dqx:F
49 3mm5:B 363 38 0.0658 0.0441 0.4211 9.4 3mm5:E, 3mm6:B, 3mm6:E, 3mm7:B, 3mm7:E, 3mm8:B, 3mm8:E, 3mm9:B, 3mm9:E, 3mma:B, 3mma:E, 3mmb:B, 3mmb:E, 3mmc:B, 3mmc:E
50 7npa:A 618 21 0.0412 0.0162 0.4762 9.9 7npa:B, 7npa:C, 7npa:D, 7npa:E, 7npa:F, 7npa:G, 7npa:H, 7npa:I, 7npa:J, 7npa:K, 7npa:L, 7npa:M, 7npa:N, 7npa:O, 7npa:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218