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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AEIKIGITMSASGPGAALGQPQSKTVAALPKEIGGEKVTYFALDDESDPTKAAQNARKLLSEEKVDVLIGSSLTPVSLPL
IDIAAEAKTPLMTMAAAAILVAPMDERRKWVYKVVPNDDIMAEAIGKYIAKTGAKKVGYIGFSDAYGEGYYKVLAAAAPK
LGFELTTHEVYARSDASVTGQVLKIIATKPDAVFIASAGTPAVLPQKALRERGFKGAIYQTHGVATEEFIKLGGKDVEGA
IFAGEAFSGAEDMPADSPFRKVKARFVDAYKAANGGAAPTIFGVHLWDSMTLVENAIPAALKAAKPGTPEFRAAIRDQIE
KSKDLALNNGLSNMTPDNHNGYDERSAFLIEIRDGAFRLKQ

The query sequence (length=361) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4dqd:A 361 361 1.0000 1.0000 1.0000 0.0 3sg0:A
2 4jb0:A 367 344 0.3712 0.3651 0.3895 4.95e-83 4eyq:A, 4fb4:A, 3tx6:A, 3uk0:A, 3ukj:A
3 3td9:A 350 362 0.2715 0.2800 0.2707 5.39e-18
4 4q6w:A 376 286 0.2050 0.1968 0.2587 4.36e-11 4q6w:B
5 4n0q:B 345 250 0.1745 0.1826 0.2520 4.80e-11 4n0q:A, 4n0q:C, 4n0q:D
6 4gnr:A 348 361 0.2327 0.2414 0.2327 1.22e-08
7 4nqr:A 364 329 0.2216 0.2198 0.2432 5.82e-08 4nqr:B, 4nv3:A, 4nv3:B, 4oat:A, 4oat:B, 4obb:A, 4obb:B, 4og2:A, 4og2:B, 4otz:A, 4otz:B, 4qym:A, 4qym:B, 4rdc:A, 4rv5:A, 4rv5:B
8 3ip5:A 348 280 0.1828 0.1897 0.2357 1.40e-07 3ip6:A, 3ip7:A, 3ip9:A, 3ipa:A, 3ipc:A
9 3i45:A 378 249 0.1801 0.1720 0.2610 1.03e-05
10 4eyg:B 364 139 0.1053 0.1044 0.2734 7.29e-04 4eyg:A
11 4mlc:A 336 168 0.1025 0.1101 0.2202 0.002 4q6b:A
12 8wch:A 396 208 0.1247 0.1136 0.2163 0.018 8wch:B
13 3i09:A 375 218 0.1440 0.1387 0.2385 0.027 3i09:B
14 3lop:A 353 193 0.1357 0.1388 0.2539 0.027
15 5c5c:A 432 90 0.0720 0.0602 0.2889 0.053
16 5k5t:A 578 199 0.1080 0.0675 0.1960 0.100
17 1z16:A 344 280 0.1662 0.1744 0.2143 0.14 1z17:A, 1z18:A
18 3mq4:A 386 86 0.0720 0.0674 0.3023 0.30
19 6e5v:B 447 110 0.0776 0.0626 0.2545 0.49 6bsz:A, 6bsz:B, 6bt5:A, 6bt5:B, 6e5v:A
20 8szh:A 835 208 0.1136 0.0491 0.1971 0.55 9asb:Q, 9asb:R, 9avg:R, 9avl:Q, 9avl:R, 9axf:R, 9ayf:R, 7dd5:A, 7dd5:B, 7e6t:B, 7e6t:A, 5fbh:B, 5fbh:A, 5fbk:A, 5fbk:B, 5k5s:A, 5k5s:B, 7m3e:A, 7m3e:B, 7m3f:A, 7m3f:B, 7m3g:A, 7m3g:B, 8szg:A, 8szh:B, 8szi:A, 8wpg:B, 8wpg:A, 8wpu:B, 8wpu:A
21 7dtv:A 779 213 0.1136 0.0526 0.1925 2.1 7dtu:A, 7dtu:B, 7dtv:B
22 8jd6:R 774 108 0.0776 0.0362 0.2593 2.2 7e9h:R, 7e9h:S, 8jd4:4, 8jd5:4, 8jd6:S
23 1usi:A 345 157 0.0997 0.1043 0.2293 2.3 1usi:C, 1usk:A, 1usk:D, 1usk:B, 1usk:C
24 8x38:A 430 90 0.0803 0.0674 0.3222 2.6
25 8szi:B 802 199 0.1080 0.0486 0.1960 3.3 9avg:Q, 9axf:Q, 9ayf:Q, 7dd6:A, 7dd6:B, 7dd7:A, 7dd7:B, 7m3j:A, 7m3j:B, 7sil:A, 7sil:B, 7sim:A, 7sim:B, 7sin:A, 7sin:B, 8szf:A, 8szf:B, 8szg:B
26 4df9:C 405 129 0.0970 0.0864 0.2713 3.6 4df9:A, 4df9:B, 4df9:D, 4df9:E, 4df9:F
27 3o0f:A 287 81 0.0693 0.0871 0.3086 8.8 3e0f:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218