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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ADREDDPNFFKMVEGFFDRGASIVEDKLVEDLKTRQTQEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVIEGYRA
QHSHQRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDEDLEKITRRFTMELAKKGFIGP
GVDVPAPNMSTGEREMSWIADTYASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFIENASYMSILGMTP
GFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGESDGSIWNPDGIDPKELEDFKLQHGTILGFPKAKIYEGSILEVDCD
ILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPQADKIFLERNIMVIPDLYLNAGGVTVSYFQILKNLNHVSYGRLTFK
YERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTA
AYVNAIEKVFRVYNEAGVTFT

The query sequence (length=501) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6dhd:A 501 501 0.9760 0.9760 0.9760 0.0 8ar7:A, 8ar7:B, 8ar7:C, 8ar7:E, 8ar7:D, 8ar7:F, 8ar8:A, 8ar8:B, 8ar8:C, 8ar8:D, 8ar8:E, 8ar8:F, 6dhd:B, 6dhd:C, 6dhd:D, 6dhd:F, 6dhd:E, 6dhk:A, 6dhk:B, 6dhk:F, 6dhk:C, 6dhk:D, 6dhk:E, 6dhk:G, 6dhk:H, 6dhk:L, 6dhk:I, 6dhk:J, 6dhk:K, 6dhl:A, 6dhl:F, 6dhl:B, 6dhl:C, 6dhl:D, 6dhl:E, 6dhl:G, 6dhl:L, 6dhl:H, 6dhl:I, 6dhl:J, 6dhl:K, 6dhm:A, 6dhm:B, 6dhm:C, 6dhm:D, 6dhm:E, 6dhm:F, 6dhn:A, 6dhn:B, 6dhn:C, 6dhn:D, 6dhn:E, 6dhn:F, 6dhq:A, 6dhq:B, 6dhq:C, 6dhq:D, 6dhq:E, 6dhq:F, 3etd:A, 3etd:E, 3etd:B, 3etd:C, 3etd:D, 3etd:F, 3ete:A, 3ete:E, 3ete:B, 3ete:C, 3ete:F, 3ete:D, 3etg:A, 3etg:B, 3etg:C, 3etg:D, 3etg:E, 3etg:F, 1hwy:A, 1hwy:B, 1hwy:F, 1hwy:C, 1hwy:E, 1hwy:D, 3jd0:A, 3jd0:B, 3jd0:C, 3jd0:D, 3jd0:E, 3jd0:F, 3jd1:A, 3jd1:C, 3jd1:B, 3jd1:D, 3jd1:F, 3jd1:E, 3jd2:A, 3jd2:B, 3jd2:C, 3jd2:D, 3jd2:E, 3jd2:F, 3jd3:A, 3jd3:B, 3jd3:C, 3jd3:D, 3jd3:E, 3jd3:F, 3jd4:A, 3jd4:C, 3jd4:B, 3jd4:D, 3jd4:F, 3jd4:E, 1nqt:A, 1nqt:B, 1nqt:F, 1nqt:C, 1nqt:D, 1nqt:E, 1nqt:G, 1nqt:H, 1nqt:L, 1nqt:I, 1nqt:J, 1nqt:K
2 3aoe:B 424 376 0.3174 0.3750 0.4229 1.25e-90 3aoe:A, 3aog:A, 3aog:E, 3aog:B, 3aog:D, 3aog:C, 3aog:F, 3aog:G, 3aog:I, 3aog:H, 3aog:J, 3aog:L, 3aog:K
3 8xd5:A 419 344 0.2934 0.3508 0.4273 2.15e-86 8hho:A, 8hiq:A, 8hiz:A, 8hj9:A, 8xco:A, 8xcp:A, 8xcq:A, 8xcr:A, 8xcs:A, 8xct:A, 8xcu:A, 8xcv:A, 8xcw:A, 8xcx:A, 8xcy:A, 8xcz:A, 8xd0:A, 8xd1:A, 8xd2:A, 8xd3:A, 8xd4:A, 8xd6:A, 8znb:A, 8znc:A, 8znd:A, 8zne:A, 8zng:A
4 8s38:B 414 327 0.3014 0.3647 0.4618 2.15e-83 8s38:A, 8s38:C, 8s39:A, 8s39:B, 8s39:C, 8s3a:A, 8s3a:B, 8s3a:C, 8s3a:D, 8s3a:E, 8s3a:F, 8s3b:A, 8s3b:B, 8s3b:C, 8s3b:D, 8s3b:E, 8s3b:F, 8s3b:G, 8s3b:H, 8s3b:I, 8s3b:J, 8s3b:K, 8s3b:L, 8s3c:B, 8s3d:A, 8s3d:B, 8s3d:C, 8s3d:D, 8s3d:E, 8s3d:F
5 4xgi:A 416 357 0.2994 0.3606 0.4202 4.06e-83 4xgi:B, 4xgi:C, 4xgi:D, 4xgi:E, 4xgi:F
6 8owm:C 413 359 0.3034 0.3680 0.4234 1.06e-81 8owm:A, 8owm:B, 8owm:D, 8owm:E, 8owm:F, 8own:A, 8own:B, 8own:C, 8own:D, 8own:E, 8own:F
7 6yeh:A 410 327 0.2894 0.3537 0.4434 7.89e-81 6yeh:B, 6yeh:C, 6yeh:D, 6yeh:E, 6yeh:F, 6yei:A, 6yei:B, 6yei:C, 6yei:D, 6yei:E, 6yei:F
8 8kar:A 414 339 0.2535 0.3068 0.3746 1.85e-72 8kao:C, 8kar:B, 8kar:C
9 1v9l:A 418 348 0.2495 0.2990 0.3592 4.78e-65 1v9l:B, 1v9l:C, 1v9l:D, 1v9l:E, 1v9l:F
10 3aoe:F 417 335 0.2216 0.2662 0.3313 1.36e-56 3aoe:E, 3aoe:C, 3aoe:D
11 1bgv:A 449 429 0.2435 0.2717 0.2844 1.54e-41
12 5gud:E 460 377 0.2236 0.2435 0.2971 1.00e-36 5gud:A, 5gud:B, 5gud:C, 5gud:D, 5gud:F, 5ijz:A, 5ijz:B, 5ijz:C, 5ijz:D, 5ijz:E, 5ijz:F, 5ijz:G, 5ijz:H, 5ijz:J
13 7f79:C 458 403 0.2056 0.2249 0.2556 4.04e-27 7f79:A, 7f79:B, 7f79:D, 7f79:E, 7f79:F
14 5xvv:B 459 383 0.2096 0.2288 0.2742 1.19e-22 5xvv:A, 5xvv:C, 5xvx:A, 5xw0:A, 5xwc:A
15 7ecr:A 460 388 0.1976 0.2152 0.2552 1.32e-21 7ecr:B, 7ecr:C, 7ecs:A, 7ecs:B, 7ecs:C, 7ect:A, 7ect:B, 7ect:C
16 8gxd:A 366 305 0.1796 0.2459 0.2951 6.20e-17
17 8hr6:A 359 304 0.1577 0.2201 0.2599 2.16e-13 8hr6:B
18 6ach:A 364 302 0.1537 0.2115 0.2550 5.13e-13 6ach:B, 6ach:C, 6ach:D, 6ach:E, 6ach:F, 6ach:G, 6ach:H
19 1bw9:A 350 306 0.1557 0.2229 0.2549 3.09e-10 1bw9:B, 1bxg:A, 1bxg:B, 1c1d:A, 1c1d:B, 1c1x:A, 1c1x:B
20 3hwo:A 379 115 0.0739 0.0976 0.3217 0.034 3hwo:B, 5jxz:A, 5jxz:B, 5jy4:A, 5jy4:B, 5jy8:A, 5jy8:B, 5jzd:A, 5jzd:B
21 6wpl:A 406 59 0.0299 0.0369 0.2542 0.43
22 6itd:A 328 67 0.0419 0.0640 0.3134 0.94 6k36:A, 6k37:A, 6k38:A
23 3gqt:C 385 30 0.0319 0.0416 0.5333 1.8 3d6b:C, 3eon:C, 3gnc:A, 3gnc:B, 3gnc:C, 3gnc:D, 3gqt:A, 3gqt:B
24 2amu:A 132 42 0.0299 0.1136 0.3571 3.1 3qzb:A
25 5k0a:D 322 46 0.0379 0.0590 0.4130 3.2 5jri:A, 5jri:B, 5k0a:A, 5k0a:B, 5k0a:C
26 6ppm:A 151 68 0.0439 0.1457 0.3235 4.9 6ppm:G, 6ppm:J
27 1h0h:A 977 49 0.0339 0.0174 0.3469 5.9 1h0h:K
28 7obr:x 488 35 0.0259 0.0266 0.3714 6.4 2go5:W, 2j37:W, 5l3q:A, 5l3q:C, 1mfq:C, 7nfx:x, 7qwq:x, 1ry1:W, 4ue5:D, 6y2z:A, 6y32:A, 6y32:C, 6y32:E, 6y32:G
29 7zc6:E 194 26 0.0220 0.0567 0.4231 8.3
30 3jaj:z 426 29 0.0220 0.0258 0.3793 9.5 6frk:x, 3jan:z, 7obq:x, 6r6g:AB

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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