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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWDMPNMDGLELLKTIRADGAMSAL
PVLMVTARAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM

The query sequence (length=128) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3rvr:B 131 128 1.0000 0.9771 1.0000 1.44e-90 1a0o:A, 1a0o:C, 1a0o:E, 1a0o:G, 2b1j:A, 2b1j:B, 1bdj:A, 1chn:A, 2che:A, 3chy:A, 5chy:A, 5d2c:A, 5d2c:B, 5dgc:A, 5dgc:B, 5dkf:A, 5dkf:B, 1f4v:A, 1f4v:B, 1f4v:C, 3f7n:A, 3f7n:B, 1ffg:A, 1ffg:C, 1ffs:A, 1ffs:C, 1ffw:A, 1ffw:C, 3fft:A, 3fft:B, 3ffw:A, 3ffw:B, 3ffx:A, 3ffx:B, 3fgz:A, 3fgz:B, 2fka:A, 2flk:A, 2flw:A, 2fmf:A, 2fmh:A, 2fmi:A, 2fmk:A, 1fqw:A, 1fqw:B, 1kmi:Y, 1mih:A, 1mih:B, 3myy:A, 3myy:B, 3olv:A, 3olv:B, 3olw:A, 3olw:B, 3olx:A, 3olx:B, 3oly:A, 3oly:B, 3oo0:A, 3oo0:B, 3oo1:A, 3oo1:B, 2pl9:A, 2pl9:B, 2pl9:C, 2pmc:A, 2pmc:B, 3rvj:A, 3rvj:B, 3rvk:A, 3rvl:A, 3rvl:B, 3rvm:A, 3rvn:A, 3rvn:B, 3rvo:A, 3rvp:A, 3rvp:B, 3rvq:A, 3rvr:A, 3rvs:A, 3rvs:B, 6tg7:A, 1u8t:A, 1u8t:B, 1ymv:A, 1zdm:A, 1zdm:B
2 4hnq:A 124 124 0.6328 0.6532 0.6532 1.45e-57 4hns:A, 4jp1:A, 4lx8:A, 3to5:A
3 3gwg:A 123 120 0.4375 0.4553 0.4667 4.15e-36 3h1e:A, 3h1g:A
4 4h60:A 120 118 0.3359 0.3583 0.3644 4.40e-21
5 2iyn:B 124 122 0.2812 0.2903 0.2951 3.28e-18 2iyn:A, 2iyn:C, 1zes:A, 1zes:B, 1zes:C
6 7od9:B 129 123 0.3047 0.3023 0.3171 8.23e-15 6ekg:Y, 6ekh:Y, 7od9:A
7 3m6m:D 118 117 0.3281 0.3559 0.3590 3.41e-14 3m6m:E, 3m6m:F
8 6ont:A 121 120 0.2812 0.2975 0.3000 4.73e-14
9 2a9r:A 118 121 0.3125 0.3390 0.3306 7.15e-14 2a9o:A, 2a9p:A, 6eb7:A, 6ebr:A, 1nxp:A, 1nxt:A
10 6rgz:D 122 118 0.3047 0.3197 0.3305 7.59e-14 6azr:B, 6azr:D, 3gl9:A, 3gl9:B, 3gl9:C, 3gl9:D, 4ja2:A, 4jas:B, 4jav:C, 4jav:D, 6rfv:C, 6rfv:D, 6rgy:C, 6rgy:D, 6rgz:C, 6rh0:C, 6rh0:D, 5uht:B, 5uht:D
11 6is1:B 121 120 0.2656 0.2810 0.2833 1.41e-13 6is1:A, 6is1:C, 6is1:D, 6is1:E, 6is1:F, 6is1:G, 6is1:H, 6is2:A, 6is2:B, 6is2:C, 6is2:D, 6is3:C
12 2r25:B 133 117 0.2812 0.2707 0.3077 9.61e-13
13 5ed4:E 224 124 0.3438 0.1964 0.3548 1.10e-12 5ed4:A, 5ed4:B, 5ed4:F, 2pmu:E
14 1mvo:A 121 120 0.2656 0.2810 0.2833 1.13e-12
15 6c40:D 118 120 0.2734 0.2966 0.2917 1.86e-12 6c40:B, 4iga:A, 3tmy:A, 3tmy:B, 4tmy:A, 4tmy:B
16 6ifh:A 119 118 0.2969 0.3193 0.3220 2.82e-12
17 1j56:A 124 102 0.2969 0.3065 0.3725 3.97e-12 1krx:A
18 7w9h:B 122 112 0.3359 0.3525 0.3839 5.77e-12 7w9h:A
19 2pl1:A 121 106 0.2656 0.2810 0.3208 8.21e-12
20 7p8e:A 126 121 0.3359 0.3413 0.3554 1.38e-11
21 6zxb:A 293 121 0.2812 0.1229 0.2975 1.98e-11 6zxb:B, 6zxc:A, 6zxc:B, 6zxc:C, 6zxc:D, 6zxm:A, 6zxm:B, 6zxm:C, 6zxm:D, 6zxm:E, 6zxm:F
22 4kny:B 226 113 0.2969 0.1681 0.3363 3.44e-11 4kfc:A, 4kfc:B, 4kny:A, 1zh2:A, 1zh2:B, 1zh4:A, 1zh4:B
23 2gwr:A 225 105 0.2422 0.1378 0.2952 3.51e-11 3nhz:B, 3nhz:C, 3nhz:D
24 6ww6:B 192 110 0.2734 0.1823 0.3182 4.64e-11 6wsh:A, 6wsh:B, 6ww6:A
25 2oqr:A 226 120 0.2891 0.1637 0.3083 5.07e-11
26 7cfw:A 123 116 0.2500 0.2602 0.2759 5.52e-11 7c1j:A
27 1l5y:B 151 118 0.3047 0.2583 0.3305 1.00e-10 1l5y:A
28 5brj:A 140 89 0.2188 0.2000 0.3146 1.17e-10
29 5xt2:B 204 104 0.2891 0.1814 0.3558 1.87e-10 5xt2:A, 5xt2:C, 5xt2:D, 5xt2:E
30 8phx:C 130 121 0.2422 0.2385 0.2562 2.29e-10 8phx:A, 8phx:B, 8phx:D
31 4yn8:A 201 122 0.2734 0.1741 0.2869 2.46e-10
32 3cg4:A 126 111 0.2500 0.2540 0.2883 2.51e-10
33 8pdc:A 122 123 0.2891 0.3033 0.3008 3.22e-10
34 1mav:A 117 120 0.2266 0.2479 0.2417 4.00e-10 1mb0:A, 1mb3:A
35 3a10:A 116 118 0.2969 0.3276 0.3220 4.41e-10 3a0u:A
36 8uvx:A 222 106 0.2344 0.1351 0.2830 4.53e-10 8uvk:A, 8uvk:B, 8uvx:B
37 6xvu:D 141 97 0.2500 0.2270 0.3299 5.77e-10 6xvu:A, 6xvu:C, 6xvu:B
38 1s8n:A 190 110 0.2578 0.1737 0.3000 7.13e-10
39 8svz:A 120 110 0.2656 0.2833 0.3091 7.87e-10 8svz:B
40 4qpj:D 121 123 0.2656 0.2810 0.2764 8.12e-10
41 7qz2:B 132 123 0.3125 0.3030 0.3252 8.84e-10 7qz2:A
42 1yio:A 198 110 0.2812 0.1818 0.3273 1.10e-09 1zn2:A
43 4euk:A 136 134 0.2656 0.2500 0.2537 1.13e-09
44 5ic5:A 166 89 0.1953 0.1506 0.2809 1.20e-09
45 7p8d:A 139 128 0.3359 0.3094 0.3359 2.90e-09 7p8d:B
46 8t85:A 335 104 0.2812 0.1075 0.3462 3.93e-09 7lcm:A
47 1ys6:B 227 104 0.2500 0.1410 0.3077 4.19e-09 1ys6:A, 1ys7:A, 1ys7:B
48 1qmp:A 126 91 0.2266 0.2302 0.3187 1.50e-08 1qmp:B, 1qmp:C, 1qmp:D
49 8jo2:H 219 93 0.2188 0.1279 0.3011 1.78e-08 8jo2:I, 4s04:A, 4s04:B, 4s04:E, 4s04:F, 4s05:A, 4s05:B, 3w9s:A, 3w9s:B
50 3nnn:A 119 121 0.2734 0.2941 0.2893 7.47e-08 3nnn:B
51 6ob8:A 307 104 0.2578 0.1075 0.3173 1.16e-07 6oap:A, 6oap:B, 6oaq:A, 6oaq:B, 6ob8:B
52 3luf:B 246 127 0.2734 0.1423 0.2756 1.35e-07 3luf:A, 3mf4:A, 3mf4:B
53 3luf:B 246 104 0.2188 0.1138 0.2692 0.007 3luf:A, 3mf4:A, 3mf4:B
54 1srr:C 121 116 0.2422 0.2562 0.2672 1.52e-07 1f51:E, 2ftk:E, 2ftk:F, 2ftk:G, 2ftk:H, 1pey:A, 1pey:B, 1pey:C, 3q15:C, 1srr:A
55 6br7:B 125 120 0.2422 0.2480 0.2583 1.84e-07 6br7:A, 6vbf:A, 6vbf:B
56 3nns:A 117 120 0.2656 0.2906 0.2833 3.55e-07 3nns:B
57 3hdg:A 124 116 0.2578 0.2661 0.2845 4.31e-07 3hdg:B, 3hdg:D, 3hdg:E
58 4zmr:A 207 122 0.2812 0.1739 0.2951 6.17e-07 4e7o:A, 4e7o:B, 4e7p:A, 4e7p:B, 4zmr:B, 4zms:A, 4zms:B
59 7lza:A 219 106 0.2578 0.1507 0.3113 6.57e-07 7lz9:A
60 5hev:F 210 109 0.2734 0.1667 0.3211 7.68e-07 5hev:A, 5hev:B, 5hev:C
61 3hzh:A 134 120 0.2578 0.2463 0.2750 8.17e-07
62 4uhk:A 130 120 0.2891 0.2846 0.3083 9.65e-07 4uhj:A, 4uhj:B, 4uhj:C, 4uhk:B, 4uhk:C, 4uhs:B, 4uhs:C
63 5lwk:A 122 116 0.2500 0.2623 0.2759 1.18e-06 5lwk:B
64 6qrj:A 463 116 0.2656 0.0734 0.2931 1.42e-06 6qrl:A, 6qrl:B
65 2v0n:A 459 105 0.2344 0.0654 0.2857 1.43e-06 2v0n:B, 1w25:A, 1w25:B, 2wb4:A, 2wb4:B
66 2v0n:A 459 121 0.2188 0.0610 0.2314 0.14 2v0n:B, 1w25:A, 1w25:B, 2wb4:A, 2wb4:B
67 1k68:A 140 109 0.2188 0.2000 0.2569 1.61e-06 1k68:B
68 7cci:B 134 119 0.2500 0.2388 0.2689 1.99e-06 7cci:A, 5xjp:A
69 1xhf:B 122 110 0.2266 0.2377 0.2636 2.14e-06 1xhf:A
70 5wq0:D 129 67 0.1641 0.1628 0.3134 3.33e-06 5wq0:B, 5wq0:A, 5wq0:C, 5wq0:E, 5wq0:F, 5wq0:G
71 3bre:B 328 110 0.2500 0.0976 0.2909 6.04e-06 3bre:A
72 5n2n:A 149 80 0.1875 0.1611 0.3000 8.96e-06 3mmn:A
73 1jlk:A 141 110 0.2109 0.1915 0.2455 1.21e-05
74 6oec:L 162 113 0.2656 0.2099 0.3009 2.23e-05 6oec:B, 6oec:C, 6oec:E, 6oec:F, 6oec:G, 6oec:I
75 6swl:A 133 120 0.2578 0.2481 0.2750 3.23e-05 6swl:B
76 4b09:A 218 118 0.2031 0.1193 0.2203 3.37e-05 4b09:B, 4b09:C, 4b09:D, 4b09:E, 4b09:F, 4b09:G, 4b09:I, 4b09:K
77 1dck:B 125 76 0.1719 0.1760 0.2895 4.32e-05 1dck:A, 1dcm:B
78 5m7o:A 448 111 0.2734 0.0781 0.3153 9.21e-05 4d6y:A, 4d6y:B, 5m7n:A, 5m7o:B, 5m7p:A, 5m7p:B
79 8tef:A 516 78 0.1719 0.0426 0.2821 1.19e-04 8p6f:A, 8p6f:B, 8ted:A, 8ted:B, 8tef:B, 8tef:C, 8tef:D, 8tff:A, 8tff:B, 8tfm:A, 8tfm:B, 8thp:A, 8thp:B
80 4if4:A 208 118 0.2422 0.1490 0.2627 1.55e-04 4if4:B, 4if4:C, 4if4:D, 7ve5:B, 7ve5:A, 7ve6:A, 7ve6:B
81 7pv7:C 514 104 0.2266 0.0564 0.2788 4.64e-04 7pv7:D, 7pv7:B, 7pv7:A, 7pva:A, 7pva:B, 7pva:C, 7pva:D, 7pvk:A, 7pvk:D, 7pvk:B, 7pvk:C
82 3dzd:A 368 120 0.2188 0.0761 0.2333 4.68e-04 3dzd:B
83 3q15:D 100 89 0.1875 0.2400 0.2697 7.20e-04
84 1ny5:B 385 117 0.2578 0.0857 0.2821 0.002 4bs1:A, 4bs1:B, 4bt0:A, 4bt0:B, 4bt1:A, 4bt1:B, 4ly6:A, 4ly6:B, 4ly6:C, 4ly6:D, 4ly6:E, 4ly6:G, 4ly6:H, 4ly6:I, 4ly6:J, 4ly6:K, 4ly6:L, 4ly6:M, 4ly6:N, 4ly6:O, 4ly6:P, 4ly6:Q, 4ly6:R, 4ly6:S, 4ly6:T, 4ly6:U, 4ly6:V, 4ly6:W, 4ly6:X, 4lzz:A, 4lzz:B, 4lzz:C, 4lzz:D, 4lzz:E, 4lzz:F, 4lzz:G, 4lzz:H, 4lzz:I, 4lzz:J, 4lzz:K, 4lzz:L, 4lzz:M, 4lzz:N, 4lzz:O, 4lzz:P, 4lzz:Q, 4lzz:R, 4lzz:S, 4lzz:T, 4lzz:U, 4lzz:V, 4lzz:W, 4lzz:X, 3m0e:A, 3m0e:B, 3m0e:C, 3m0e:D, 3m0e:E, 3m0e:F, 3m0e:G, 1ny5:A, 1ny6:A, 1ny6:B, 1ny6:C, 1ny6:D, 1ny6:E, 1ny6:F, 1ny6:G, 1ny6:H, 1ny6:I, 1ny6:J, 1ny6:K, 1ny6:L, 1ny6:M, 1ny6:N, 1zy2:A
85 5m7n:B 428 110 0.2656 0.0794 0.3091 0.004
86 3i5a:A 319 56 0.1328 0.0533 0.3036 0.005
87 7e1b:A 209 64 0.1484 0.0909 0.2969 0.006 7e1b:B, 7e1b:C, 7e1b:H, 7e1b:D, 7e1b:E, 7e1b:F, 7e1b:G, 7e1h:A, 7e1h:B, 7e1h:E
88 4tv5:A 245 63 0.1641 0.0857 0.3333 0.044 4tv6:A
89 6hiv:DD 791 66 0.1562 0.0253 0.3030 0.044 6hiw:DD, 6hiy:DD, 7pua:DD, 7pub:DD, 6sga:DD, 6sgb:DD
90 8phn:A 124 117 0.2031 0.2097 0.2222 0.33
91 4ldz:A 196 74 0.1641 0.1071 0.2838 0.34 5iuk:C, 5iul:C, 5iul:F, 4ldz:B, 4le0:A, 4le0:B, 7ssj:B, 7ssj:E, 7ssj:F
92 4nic:A 117 62 0.1406 0.1538 0.2903 0.40 4nic:B, 4nic:C, 4nic:D
93 2m98:A 123 64 0.1484 0.1545 0.2969 0.77
94 7ytj:E 650 50 0.1250 0.0246 0.3200 1.3
95 5syt:A 444 50 0.1328 0.0383 0.3400 1.4 4aw6:A, 4aw6:B, 4aw6:D, 4aw6:E, 6bh8:B
96 5wm3:A 537 51 0.1406 0.0335 0.3529 1.7 5wm2:A, 5wm4:A, 5wm5:A, 5wm6:A, 5wm7:A
97 7pua:IA 704 41 0.1328 0.0241 0.4146 2.5 7pub:IA
98 8qcj:A 458 103 0.1953 0.0546 0.2427 4.6 8qcj:B
99 6ueb:A 2099 24 0.0781 0.0048 0.4167 5.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218