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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ADGPYSGILDSVLDAIGNTPMVRMKRLAKVYGLECDLLAKCEFMSAGGSVKDRIGKAMVEKAEREGRLKAGDTLIEPTSG
NTGIGLALAAAVRGYRMIVTMPAKMSAEKSNIMKCLGAEIVRTPTEAAWNDENSHMGVAAKLQRELENAHILDQYNNTAN
PMVHYDVTAEEIITQCDGDIDMVVIGAGTGGTITGIGRKIKERCPKCKVVGVDPKGSILAVPDSLNDEKRLQSYEVEGIG
YDFVPGVLDRKVVDEWVKVGDAESFTTARAIIRNEGLFVGGSSGANVWGALQAARQLKKGQKCVVLLPDSSRNYMSKFIS
DEWMAEHGFAPEDGAKVKEREKQFGGARIRDLLSETGTSDVPFVTARLSVEDVIKMMHETKVKEVIVTEDLVGVLSEDHI
AHSLQSGRCAMQSPVKDIAFKKLAKALPSAYLRDVAKALDFSPYVCVMDPHFLGVITRIDLLHWLATK

The query sequence (length=468) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6xwl:C 477 476 1.0000 0.9811 0.9832 0.0 6xwl:F, 6xwl:A, 6xwl:B, 6xwl:D, 6xwl:E, 6xyl:A, 6xyl:B, 6xyl:C, 6xyl:D, 6xyl:E, 6xyl:F, 6y21:D, 6y21:A, 6y21:B, 6z3s:D, 6z3s:A, 6z3s:B, 6zs7:D, 6zs7:A, 6zs7:B, 6zs7:C, 6zs7:E, 6zs7:F
2 8s5h:A 507 478 0.4850 0.4477 0.4749 3.51e-157 4coo:A, 4coo:B, 1jbq:A, 1jbq:B, 1jbq:C, 1jbq:D, 1jbq:E, 1jbq:F, 4l0d:A, 4l0d:B, 4l27:B, 4l27:D, 4l27:A, 4l27:C, 4l28:A, 4l28:B, 4l28:C, 4l28:D, 4l3v:B, 4l3v:A, 4l3v:C, 1m54:A, 1m54:B, 1m54:C, 1m54:D, 1m54:E, 1m54:F, 5mms:A, 5mms:F, 5mms:B, 5mms:C, 5mms:D, 5mms:E, 4pcu:A, 4pcu:B, 7qgt:A, 7qgt:B, 8s5h:B, 8s5h:C, 8s5h:D, 8s5h:E, 8s5h:F, 8s5h:G, 8s5h:H, 8s5i:A, 8s5i:B, 8s5i:C, 8s5i:D, 8s5i:E, 8s5i:F, 8s5j:A, 8s5j:B, 8s5j:C, 8s5j:D, 8s5j:E, 8s5j:F, 8s5j:G, 8s5j:H, 8s5j:I, 8s5j:J, 8s5k:A, 8s5k:B, 8s5k:C, 8s5k:D, 8s5k:E, 8s5k:F, 8s5k:G, 8s5k:H, 8s5l:A, 8s5l:B, 8s5l:C, 8s5l:D, 8s5m:A, 8s5m:B, 8s5m:C, 8s5m:D, 8s5m:E, 8s5m:F, 8s5m:G, 8s5m:H, 8s5m:I, 8s5m:J, 8stw:A, 8stw:B, 8stw:C, 8stw:D, 8stw:E, 8stw:F, 4uuu:A, 4uuu:B
3 5ohx:A 488 472 0.4423 0.4242 0.4386 5.74e-125 5ohx:B
4 3pc3:A 504 470 0.4423 0.4107 0.4404 1.95e-124 3pc2:A, 3pc4:A
5 6vju:B 317 322 0.4124 0.6088 0.5994 2.45e-120
6 6c2h:A 345 333 0.3590 0.4870 0.5045 1.06e-111 6c2q:A, 6c2z:A, 6c4p:A
7 7xnz:B 458 479 0.3611 0.3690 0.3528 1.13e-69 7xnz:A, 7xnz:C, 7xnz:D, 7xoh:B, 7xoh:A, 7xoh:C, 7xoh:D, 7xoy:B, 7xoy:A, 7xoy:C, 7xoy:D
8 2q3d:A 306 310 0.2778 0.4248 0.4194 1.32e-64 2q3c:A, 3zei:A
9 6ahi:B 306 312 0.2286 0.3497 0.3429 7.39e-63
10 2eco:A 302 307 0.2799 0.4338 0.4267 1.46e-59 2ecq:A, 2efy:A, 2efy:B, 1ve1:A
11 4aec:A 323 314 0.2863 0.4149 0.4268 1.61e-59 4aec:B
12 4lmb:A 310 311 0.2500 0.3774 0.3762 4.17e-57
13 7n2t:A 309 320 0.2778 0.4207 0.4062 1.98e-56
14 4lma:A 318 314 0.2564 0.3774 0.3822 1.06e-54 4lma:B
15 5b1i:A 303 312 0.2350 0.3630 0.3526 1.25e-54 5b1i:B, 5b1i:C, 5b1i:D, 5b1i:E, 5b1i:F, 5b1i:G, 5b1i:H
16 7mfj:BBB 319 317 0.2415 0.3542 0.3565 3.02e-54
17 2isq:A 320 321 0.2735 0.4000 0.3988 3.97e-53 1z7w:A, 1z7y:A
18 5d84:A 318 317 0.2265 0.3333 0.3344 1.23e-51 5d85:A, 5d86:A, 5d87:A
19 5xoq:A 310 307 0.2650 0.4000 0.4039 6.01e-51 5xoq:B
20 2bht:A 294 318 0.2436 0.3878 0.3585 5.01e-50 2bhs:A, 2bhs:B, 2bhs:C, 2bhs:D, 2bht:B, 2bht:C, 2bht:D, 2jc3:A, 2jc3:H, 2jc3:B, 2jc3:C, 2jc3:D, 2jc3:E, 2jc3:F, 2jc3:G, 2v03:A
21 8b9w:A 329 308 0.2457 0.3495 0.3734 5.30e-49 8b9w:B
22 3x44:A 321 315 0.2350 0.3427 0.3492 1.42e-48 3x43:A, 3x43:B, 3x43:C, 3x43:D, 3x43:E, 3x43:F, 3x43:G, 3x43:H, 3x44:B
23 3vbe:C 329 328 0.2543 0.3617 0.3628 1.60e-48 3vbe:A, 3vbe:B, 3vbe:D, 3vc3:A, 3vc3:B, 3vc3:C, 3vc3:D, 3vc3:E, 3vc3:F
24 1d6s:A 322 316 0.2521 0.3665 0.3734 4.61e-48 1d6s:B, 1fcj:A, 1fcj:B, 1fcj:C, 1fcj:D, 1oas:A, 1oas:B, 6z4n:AAA, 6z4n:BBB
25 6xo2:A 294 317 0.2244 0.3571 0.3312 9.32e-46 7mfj:AAA, 6pmu:A, 6pmu:B
26 3t4p:A 319 311 0.2265 0.3323 0.3408 1.75e-45 3tbh:A
27 5xem:A 302 316 0.2265 0.3510 0.3354 2.72e-45 5xem:B, 5xen:A, 5xen:B, 5xeo:A, 5xeo:B
28 3bm5:A 338 316 0.2222 0.3077 0.3291 4.18e-45 3bm5:B, 4il5:A, 4jbl:B, 4jbn:A, 2pqm:A, 2pqm:B
29 6kr5:B 336 321 0.2308 0.3214 0.3364 1.30e-42 6kr5:A
30 8b9y:C 330 331 0.2415 0.3424 0.3414 2.94e-41 8b9y:A, 8b9y:B, 8b9y:D
31 5dbh:X 312 304 0.2393 0.3590 0.3684 1.26e-39 6aif:A, 5dbe:X, 7djq:A, 3iqg:X, 3iqh:X, 3iqi:X, 4li3:X, 4nu8:X, 4ore:X, 1y7l:A, 7yod:A, 7yoh:A, 7yoi:A, 7yol:A, 7yom:A, 4zu1:X, 4zu6:X
32 3dwg:A 325 281 0.2051 0.2954 0.3416 3.49e-37 3dwg:B, 3dwi:A, 3dwi:B, 5i6d:B, 5i6d:C, 5i6d:D, 5i7a:B, 5i7a:C, 5i7a:D, 5i7h:B, 5i7h:C, 5i7h:D, 5i7o:B, 5i7o:C, 5i7o:D, 5i7r:B, 5i7r:A, 5iw8:A, 5iw8:B
33 4air:A 304 311 0.2073 0.3191 0.3119 9.45e-37 4air:B
34 5iwc:A 297 281 0.1966 0.3098 0.3274 4.82e-34 5i6d:A, 5i7a:A, 5i7h:A, 5i7o:A, 5iwc:B
35 5z5c:B 336 326 0.2094 0.2917 0.3006 9.69e-34 5b53:A, 5b55:A, 5b55:B, 5z5c:A, 5z5c:C, 5z5c:D
36 8if7:A 342 324 0.2073 0.2836 0.2994 2.91e-23
37 8h4q:N 488 287 0.1838 0.1762 0.2997 1.07e-14 8h4h:N, 8h4h:A, 8h4q:A
38 5b36:B 383 310 0.1731 0.2115 0.2613 2.71e-09 5b36:A, 5b3a:A, 5b3a:B, 6l0p:A, 6l0p:B, 6l0p:C, 6l0p:D, 6l0q:A, 6l0q:B, 6l0q:C, 6l0q:D, 6l0r:A, 6l0r:B, 6l0r:C, 6l0r:D, 6l0s:A, 6l0s:B, 6l0s:C, 6l0s:D, 3vsa:A, 3vsa:B, 3vsc:A, 3vsc:B, 3vsd:A, 3vsd:B, 1wkv:A, 1wkv:B
39 8y1j:A 502 211 0.1197 0.1116 0.2654 1.01e-08 8y1j:B
40 6nmx:A 350 311 0.1838 0.2457 0.2765 2.41e-08 6cgq:A, 6cgq:B, 6nmx:B, 6nmx:C, 6nmx:D
41 7nbc:AAA 323 207 0.1132 0.1641 0.2560 3.59e-07 3hmk:A, 3hmk:B, 3l6b:A, 3l6c:A, 3l6c:B, 3l6r:A, 7nbc:BBB, 7nbc:CCC, 7nbc:DDD, 7nbd:AAA, 7nbd:BBB, 7nbd:DDD, 7nbd:CCC, 7nbf:AAA, 7nbf:CCC, 7nbf:BBB, 7nbf:DDD, 7nbg:AAA, 7nbg:BBB, 7nbg:CCC, 7nbg:DDD, 7nbh:AAA, 7nbh:BBB, 7nbh:CCC, 7nbh:DDD, 6slh:AAA, 6slh:BBB, 6slh:CCC, 6slh:DDD, 5x2l:A, 5x2l:B, 6zsp:AAA, 6zsp:BBB, 6zuj:AAA, 6zuj:BBB, 6zuj:CCC, 6zuj:DDD
42 5cvc:A 329 222 0.1111 0.1581 0.2342 7.21e-06 5cvc:B, 5cvc:C
43 6hul:B 416 337 0.1624 0.1827 0.2255 2.43e-05
44 1tdj:A 494 208 0.1132 0.1073 0.2548 0.008
45 2zpu:A 319 258 0.1346 0.1975 0.2442 0.020 1v71:A, 1wtc:A, 2zr8:A
46 8vhh:A 389 106 0.0620 0.0746 0.2736 0.036 8egy:A, 8egy:B, 8egz:A, 8egz:B, 8eh0:A, 8eh0:B, 8eh1:A, 8eh1:B, 8vhh:B
47 4d9k:A 366 120 0.0705 0.0902 0.2750 0.048 4d9k:B, 4d9k:C
48 1j0a:A 325 170 0.0833 0.1200 0.2294 0.079 1j0a:B, 1j0a:C, 1j0b:A, 1j0b:B, 1j0b:C, 1j0b:D, 1j0b:E, 1j0b:F, 1j0b:G, 1j0b:H, 1j0b:I, 1j0b:J, 1j0b:K, 1j0b:L, 1j0b:M, 1j0b:N, 1j0b:O, 1j0b:P, 1j0b:Q, 1j0b:R, 1j0b:S, 1j0b:T, 1j0b:U, 1j0b:V, 1j0b:W, 1j0b:X
49 2zsj:A 350 66 0.0449 0.0600 0.3182 0.094 2zsj:B, 2zsj:C, 2zsj:D
50 4qys:B 418 122 0.0662 0.0742 0.2541 0.094 6hte:B, 6hte:D, 4qys:A
51 6emu:A 170 74 0.0427 0.1176 0.2703 0.20 6emu:B, 6emu:C, 6emv:A, 6emv:B, 6emv:C
52 4d9n:A 391 51 0.0385 0.0460 0.3529 0.46 4d9m:A, 4d9m:B, 4d9n:B
53 3fim:B 565 105 0.0598 0.0496 0.2667 0.55 5oc1:A
54 1m6y:A 293 61 0.0321 0.0512 0.2459 0.61 1m6y:B, 1n2x:A, 1n2x:B
55 2ykk:A 512 76 0.0513 0.0469 0.3158 0.79 2yih:A, 2yjq:A, 2yjq:B, 3zq9:A
56 5ygr:B 365 115 0.0684 0.0877 0.2783 0.88
57 3r0x:A 438 122 0.0684 0.0731 0.2623 1.2
58 4d8u:H 331 213 0.1111 0.1571 0.2441 1.6 4d8u:A, 4d8u:B, 4d8u:C, 4d8u:D, 4d8u:E, 4d8u:F, 4d8u:G, 4d8w:A, 4d8w:C, 4d8w:D, 4d92:A, 4d92:B, 4d92:C, 4d92:D, 4d96:A, 4d96:B, 4d96:C, 4d96:D, 4d97:A, 4d97:B, 4d97:C, 4d97:D, 4d99:A, 4d99:B, 4d99:C, 4d99:D, 4d9b:A, 4d9b:B, 4d9b:C, 4d9b:D, 4d9c:A, 4d9c:B, 4d9c:C, 4d9c:D, 4d9e:A, 4d9e:B, 4d9e:C, 4d9e:D, 4d9f:A, 4d9f:B, 4d9f:C, 4d9f:D
59 3sxp:D 314 186 0.0897 0.1338 0.2258 2.1 3sxp:A, 3sxp:B, 3sxp:C, 3sxp:E
60 4rvu:A 329 64 0.0491 0.0699 0.3594 2.3 4rvu:B, 4rvu:C, 4rvu:D
61 3aex:A 351 311 0.1624 0.2165 0.2444 3.1 3aex:B, 3aey:A, 3aey:B, 1uim:A, 1uim:B, 1uin:A, 1uin:B, 1v7c:A, 1v7c:B, 1v7c:C, 1v7c:D
62 5frp:A 677 46 0.0321 0.0222 0.3261 3.7 5frp:B, 5frs:A
63 8osg:B 323 56 0.0406 0.0588 0.3393 5.0 8osf:A, 8osf:B, 8osf:C, 8osf:D, 8osf:E, 8osg:C, 8osg:D, 8osg:E
64 3gn6:C 301 69 0.0427 0.0664 0.2899 5.2 3gn6:A, 3gn6:B, 3gn6:D
65 5c3u:A 315 88 0.0556 0.0825 0.2955 5.3
66 1ve5:A 308 199 0.1090 0.1656 0.2563 5.9 1ve5:B
67 5ygr:D 388 50 0.0363 0.0438 0.3400 6.4 5ygr:A, 5ygr:C
68 3ss7:X 437 140 0.0855 0.0915 0.2857 7.3 3ss9:X
69 8pzk:A 300 92 0.0577 0.0900 0.2935 7.5
70 2abj:A 366 70 0.0449 0.0574 0.3000 7.5 2abj:D, 2abj:G, 2abj:J, 2cog:A, 2cog:B, 2coi:A, 2coi:B, 2coj:A, 2coj:B, 7ntr:A, 7ntr:B, 7nwa:A, 7nwa:B, 7nwb:A, 7nwb:B, 7nwb:C, 7nwb:D, 7nwc:A, 7nwc:B, 7nwc:C, 7nwc:D, 7nwe:A, 7nwe:B, 7nwm:A, 7nwm:B, 7nxn:A, 7nxn:B, 7nxo:A, 7nxo:B, 7ny2:A, 7ny2:B, 7ny9:A, 7ny9:B, 7nya:A, 7nya:B
71 4n0l:A 335 39 0.0299 0.0418 0.3590 8.1 4n0l:B
72 7rzw:B 864 95 0.0534 0.0289 0.2632 10.0 7rzw:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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