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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ADFQPSIWGDLFLNCPDDAETEKRHQQLKEEVRKMIVAPMANSTQKLAFIDSVQRLGVSYHFTKEIEDELENIYHNNNDA
ENDLYTTSIRFRLLREHGYNVSCDVFNKFKDEQGNFKSSVTSDVRGLLELYQASYLRVHGEDILDEAISFTTHHLSLAVA
SLDHPLSEEVSHALKQSIRRGLPRVEARHYLSVYQDESHNKALLEFAKIDFNMLQFLHRKELSEICRWWKDLDFQRKLPY
ARDRVVEGYFWISGVYFEPQYSLGRKMLTKVIAMASIVDDTYDSYATYEELIPYTNAIERWDIKCIDEIPEYMKPSYKAL
LDVYEEMVQLVAEHGRQYRVEYAKNAMIRLAQSYLVEAKWTLQNYKPSFEEFKANALPTCGYAMLAITSFVGMGDIVTPE
TFKWAASDPKIIQASTIICRFMDDVAEHKFDCSAIECYMEEYGVTAQEAYDVFNKHVESAWKDLNQEFLKPTEMPTEVLN
RSLNLARVMDVLYREYVGKAAKGGITSLLIEPIAL

The query sequence (length=515) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3g4f:A 515 515 1.0000 1.0000 1.0000 0.0 3g4f:B
2 5dhi:A 536 533 0.4835 0.4646 0.4672 4.32e-168 5dhk:A, 4di5:A, 5eas:A, 5eat:A, 5eau:A, 1hx9:A, 1hxa:A, 1hxc:A, 1hxg:A, 5ik0:A, 5ik6:A, 5ik9:A, 5ika:A, 5ikh:A, 5il3:A, 5il8:A, 5ild:A, 5ilh:A, 5ili:A, 5ily:A, 3lz9:A, 3m00:A, 3m01:A, 3m02:A, 4rnq:A
3 7xkw:A 499 504 0.4194 0.4329 0.4286 1.26e-146
4 7bzc:A 535 538 0.3864 0.3720 0.3699 1.53e-111 7bzb:A
5 6a1i:A 522 499 0.3495 0.3448 0.3607 1.46e-98 6a1d:A, 6a1e:A, 6a3x:A, 7e9r:B, 7e9r:C, 6k16:A, 6o9p:A
6 6a2d:A 519 521 0.3515 0.3487 0.3474 2.55e-95 6a2c:A, 6a2c:B, 6a2d:B
7 5uv2:A 514 525 0.3456 0.3463 0.3390 3.46e-94 6onm:A, 5uv1:A
8 1n1z:A 537 544 0.3359 0.3222 0.3180 2.68e-89 1n1b:A, 1n1b:B, 1n1z:B, 1n20:A, 1n20:B, 1n21:A, 1n22:A, 1n22:B, 1n23:A, 1n23:B, 1n24:A, 1n24:B
9 3n0g:B 524 506 0.3126 0.3073 0.3182 7.10e-89 3n0g:A
10 2ong:A 543 539 0.3301 0.3131 0.3154 9.76e-88 2ong:B, 2onh:A, 2onh:B
11 3sae:A 780 520 0.3243 0.2141 0.3212 4.06e-76 3sdr:A, 3sdt:A, 3sdu:A, 3sdv:A
12 3p5r:A 750 511 0.2913 0.2000 0.2935 8.11e-61 3p5p:A, 3p5r:B
13 7y47:B 767 500 0.2485 0.1669 0.2560 8.00e-40
14 3pya:A 688 255 0.1476 0.1105 0.2980 1.22e-18 4lix:A, 3pyb:A
15 8ih5:A 689 299 0.1631 0.1219 0.2809 3.17e-17 8ih5:F, 8ih5:B, 8ih5:C, 8ih5:D, 8ih5:E
16 5hlo:C 93 86 0.0485 0.2688 0.2907 0.25 6ds2:A, 6ds2:C, 6ds2:E, 6ds2:G, 4ggf:A, 4ggf:K, 4ggf:S, 4ggf:U, 5hlo:A, 5hlo:B, 5hlo:D, 5hlv:A, 5hlv:D, 5hlv:B, 5hlv:H, 5hlv:C, 5hlv:E, 5hlv:F, 5hlv:G, 1mr8:A, 1mr8:B, 7quv:A, 8sjb:A, 8sjb:B, 8sjc:A, 8sjc:B, 5w1f:A, 5w1f:C, 5w1f:G, 5w1f:E, 4xjk:A, 4xjk:C, 4xjk:E, 4xjk:G, 4xjk:I, 1xk4:A, 1xk4:B, 1xk4:E, 1xk4:F, 1xk4:I, 1xk4:J
17 8wce:A 994 124 0.0641 0.0332 0.2661 2.4
18 5b6p:B 145 71 0.0447 0.1586 0.3239 3.1 5b6p:C, 5b6p:G, 5ydb:A, 5ydb:B, 5ydb:C, 5ydb:D
19 7alt:A 270 35 0.0311 0.0593 0.4571 5.2 7alt:B
20 8esq:I 460 44 0.0252 0.0283 0.2955 5.5
21 6xyw:Bz 123 62 0.0330 0.1382 0.2742 5.5
22 6bhd:A 217 80 0.0466 0.1106 0.3000 6.2 6au2:A, 6au3:A, 6bhe:A, 6bhg:A, 6bhh:A, 6bhi:A, 6bpi:A, 7c9n:B, 7c9n:A, 7caj:D, 7caj:A, 7cd9:A, 7cd9:B, 7cjt:D, 7cjt:A, 7cjt:B, 7cjt:C, 8g5e:A, 5kch:A, 5kco:A, 5ke2:A, 5ke3:A, 5kh6:A, 5qt1:A, 5qt2:A, 8uwp:A, 8uwp:B
23 2ph5:A 459 71 0.0447 0.0501 0.3239 6.8
24 8d32:A 186 96 0.0447 0.1237 0.2396 7.1 6wgs:A, 6wgv:A, 6wh5:A, 6wh5:B, 6wh5:C
25 6t0q:A 340 54 0.0311 0.0471 0.2963 7.4 6kbj:A, 6kbq:A, 6kc2:A, 6li7:A, 6lik:A, 6t1d:A, 6t1d:B, 6t1d:C, 6t1d:D, 6t1d:E, 6t1d:F
26 5buo:A 185 87 0.0408 0.1135 0.2414 8.8 3umi:A, 3umk:A
27 7n2x:A 201 63 0.0408 0.1045 0.3333 9.9 2d5i:A, 1v4b:A, 2z98:A, 2z9b:A, 2z9c:A, 2z9d:A, 2z9d:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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