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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ADELVFFVNGKKVVEKNADPETTLLVYLRRKLGLCGTKLGCGEGGCGACTVMISKYDRLQNKIVHFSVNACLAPICSLHH
VAVTTVEGIGNTQKLHPVQERIARSHGSQCGFCTPGIVMSMYTLLRNQPEPTVEEIENAFQGNLCRCTGYRPILQGFRTF
AKDGPSLFNPEDFKPLDPTQEPIFPPELLRLKDTPQKKLRFEGERVTWIQASTMEELLDLKAQHPDAKLVVGNTEIGIEM
KFKNMLFPLIVCPAWIPELNSVVHGPEGISFGASCPLSLVESVLAEEIAKLPEQKTEVFRGVMEQLRWFAGKQVKSVASI
GGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVRMDHTFFPGYRKTLLRPEEILLSIEIPYSKEGEFFSAFKQASRRE
ADIAKVTSGMRVLFKPGTIEVQELSLCFGGMADRTISALKTTPKQLSKSWNEELLQSVCAGLAEELQLAPDAPGGMVEFR
RTLTLSFFFKFYLTVLQKLGRADLEDMCGKLDPTFASATLLFQKDPPANVQLFQEVPKDQSEEDMVGRPLPHLAANMQAS
GEAVYCDDIPRYENELSLRLVTSTRAHAKITSIDTSEAKKVPGFVCFLTAEDVPNSNATGLFNDETVFAKDEVTCVGHII
GAVVADTPEHAQRAARGVKITYEDLPAIITIQDAINNNSFYGSEIKIEKGDLKKGFSEADNVVSGELYIGGQEHFYLETN
CTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPDNRIVVRVKRMGGGFGGKETRSTVVSTALALAAHKTGRPVRCML
DRDEDMLITGGRHPFLAKYKVGFMKTGTVVALEVAHFSNGGNTEDLSRSIMERALFHMDNAYKIPNIRGTGRICKTNLPS
NTAFRGFGGPQGMLIAEYWMSEVAITCGLPAEEVRRKNMYKEGDLTHFNQKLEGFTLPRCWDECIASSQYLARKREVEKF
NRENCWKKRGLCIIPTKFGISFTLPFLNQGGALVHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIHISETS
TNTVPNTSPTAASASADLNGQGVYEACQTILKRLEPFKKKKPTGPWEAWVMDAYTSAVSLSATGFYKTPNLGYSFETNSG
NPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTMEELHYSPEGSLHTRGPSTY
KIPAFGSIPIEFRVSLLRDCPNKRAIYASKAVGEPPLFLASSIFFAIKDAIRAARAQHKQLFQLDSPATPEKIRNACVDQ
FTTLCVTCKSWSVRI

The query sequence (length=1295) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2e1q:A 1307 1307 0.9050 0.8967 0.8967 0.0 6a7x:A, 6a7x:B, 6abu:A, 6abu:B, 6ac1:A, 6ac1:B, 6ac4:A, 6ac4:B, 6ad4:A, 6ad4:B, 6adj:A, 6adj:B, 6aju:A, 6aju:F, 3an1:A, 3an1:B, 3b9j:A, 3b9j:I, 2ckj:B, 2ckj:C, 2ckj:D, 2e1q:B, 2e1q:C, 2e1q:D, 2e3t:A, 2e3t:B, 3etr:A, 3etr:L, 3eub:A, 3eub:J, 3eub:S, 3eub:2, 1fiq:A, 3nrz:A, 3nrz:J, 3ns1:A, 3ns1:J, 3nvv:A, 3nvv:J, 3nvw:A, 3nvw:J, 3nvy:A, 3nvy:J, 3nvz:A, 3nvz:J, 3sr6:A, 3sr6:J, 1wyg:A, 4yrw:A, 4yrw:B, 4ysw:A, 4ysw:B, 4yty:A, 4yty:B, 4ytz:A, 4ytz:B
2 2ckj:A 1264 1293 0.8803 0.9019 0.8817 0.0
3 1fo4:A 1299 1306 0.8656 0.8630 0.8583 0.0 3am9:A, 3am9:B, 3amz:A, 3amz:B, 3b9j:B, 3b9j:C, 3b9j:J, 3b9j:K, 3bdj:A, 3bdj:B, 3etr:B, 3etr:C, 3etr:M, 3etr:N, 3eub:B, 3eub:C, 3eub:K, 3eub:L, 3eub:T, 3eub:U, 3eub:3, 3eub:4, 1fiq:B, 1fo4:B, 8j79:A, 8j79:B, 1n5x:A, 1n5x:B, 3nrz:B, 3nrz:C, 3nrz:K, 3nrz:L, 3ns1:B, 3ns1:C, 3ns1:K, 3ns1:L, 3nvv:B, 3nvv:C, 3nvv:K, 3nvv:L, 3nvw:B, 3nvw:C, 3nvw:K, 3nvw:L, 3nvy:B, 3nvy:C, 3nvy:K, 3nvy:L, 3nvz:B, 3nvz:C, 3nvz:K, 3nvz:L, 3sr6:B, 3sr6:C, 3sr6:K, 3sr6:L, 3una:A, 3una:B, 3unc:A, 3unc:B, 3uni:A, 3uni:B, 1v97:A, 1v97:B, 1vdv:A, 1vdv:B
4 3ax7:A 1225 1293 0.8193 0.8661 0.8206 0.0 3ax7:B, 3ax9:A, 3ax9:B
5 7orc:B 1299 1291 0.5058 0.5042 0.5074 0.0 5epg:A, 7opn:A, 7opn:B, 7orc:A, 6q6q:A, 4uhw:A, 4uhx:A
6 3zyv:B 1262 1297 0.5042 0.5174 0.5035 0.0 3zyv:A, 3zyv:C, 3zyv:D
7 8emt:A 1254 1290 0.4927 0.5088 0.4946 0.0
8 8emt:B 1221 1288 0.4865 0.5160 0.4891 0.0
9 1jro:B 760 754 0.2510 0.4276 0.4310 5.52e-171 1jro:D, 1jro:F, 1jro:H, 1jrp:B, 1jrp:D, 1jrp:F, 1jrp:H, 2w3r:B, 2w3r:D, 2w3r:F, 2w3r:H, 2w3s:B, 2w3s:D, 2w3s:F, 2w3s:H, 2w54:B, 2w54:D, 2w54:F, 2w54:H, 2w55:B, 2w55:D, 2w55:F, 2w55:H
10 7px0:B 1253 1310 0.3066 0.3168 0.3031 1.77e-155 7px0:A, 7px0:C, 7px0:D
11 4c7y:A 907 795 0.1707 0.2437 0.2780 5.87e-62 4c7z:A, 4c80:A, 3fah:A, 3fc4:A, 3l4p:A, 1sij:A, 4us8:A, 4us9:A, 4usa:A, 1vlb:A
12 4c7y:A 907 156 0.0479 0.0684 0.3974 9.20e-25 4c7z:A, 4c80:A, 3fah:A, 3fc4:A, 3l4p:A, 1sij:A, 4us8:A, 4us9:A, 4usa:A, 1vlb:A
13 1dgj:A 906 758 0.1575 0.2252 0.2691 4.49e-55
14 1dgj:A 906 139 0.0432 0.0618 0.4029 6.38e-23
15 1jro:A 450 466 0.1143 0.3289 0.3176 3.73e-53 1jro:C, 1jro:E, 1jro:G, 1jrp:A, 1jrp:C, 1jrp:E, 1jrp:G, 2w3r:A, 2w3r:C, 2w3r:E, 2w3r:G, 2w3s:A, 2w3s:C, 2w3s:E, 2w3s:G, 2w54:A, 2w54:C, 2w54:E, 2w54:G, 2w55:A, 2w55:C, 2w55:E, 2w55:G
16 7dqx:D 770 725 0.1390 0.2338 0.2483 5.67e-45 7dqx:A
17 3hrd:A 420 359 0.0865 0.2667 0.3120 6.65e-44 3hrd:E
18 1rm6:A 761 723 0.1405 0.2392 0.2517 4.97e-41 1rm6:D, 1sb3:A, 1sb3:D
19 1t3q:B 786 756 0.1490 0.2455 0.2553 2.40e-37 1t3q:E
20 4zoh:C 161 160 0.0486 0.3913 0.3937 2.32e-32
21 1ffu:D 156 155 0.0510 0.4231 0.4258 4.02e-30 1ffu:A, 1ffv:A, 1ffv:D
22 4zoh:A 701 741 0.1405 0.2596 0.2456 7.30e-29
23 1sb3:C 161 162 0.0494 0.3975 0.3951 2.25e-27 1rm6:C, 1rm6:F, 1sb3:F
24 5g5g:C 731 738 0.1498 0.2654 0.2629 5.79e-27 5g5h:C
25 1ffu:B 797 788 0.1344 0.2183 0.2208 1.56e-26 1ffu:E, 1ffv:B, 1ffv:E
26 3hrd:B 330 324 0.0734 0.2879 0.2932 2.06e-26 3hrd:F
27 1n63:B 805 783 0.1436 0.2311 0.2375 3.28e-26 1n5w:B, 1n5w:E, 1n60:B, 1n60:E, 1n61:B, 1n61:E, 1n62:B, 1n62:E, 1n63:E, 1zxi:B, 1zxi:E
28 1t3q:A 162 150 0.0409 0.3272 0.3533 1.20e-24 1t3q:D
29 5g5g:A 175 176 0.0494 0.3657 0.3636 5.20e-24 5g5h:A
30 1n5w:A 161 155 0.0432 0.3478 0.3613 2.19e-23 1n5w:D, 1n60:A, 1n60:D, 1n61:A, 1n61:D, 1n62:A, 1n62:D, 1n63:A, 1n63:D, 1zxi:A, 1zxi:D
31 5y6q:A 157 161 0.0440 0.3631 0.3540 5.68e-22
32 8gy3:B 154 159 0.0425 0.3571 0.3459 2.78e-21
33 3hrd:D 160 140 0.0402 0.3250 0.3714 3.47e-21 3hrd:H
34 7dqx:C 160 142 0.0363 0.2938 0.3310 1.16e-20 7dqx:F
35 5y6q:C 748 701 0.1143 0.1979 0.2111 1.55e-15
36 8gy3:C 732 286 0.0564 0.0997 0.2552 2.03e-12
37 8gy3:C 732 106 0.0208 0.0369 0.2547 0.042
38 1ffu:C 287 208 0.0425 0.1916 0.2644 1.32e-06 1ffu:F, 1ffv:C, 1ffv:F
39 7dqx:E 293 200 0.0378 0.1672 0.2450 7.10e-06 7dqx:B
40 4zoh:B 274 189 0.0340 0.1606 0.2328 9.44e-06
41 1t3q:C 285 244 0.0402 0.1825 0.2131 0.001 1t3q:F
42 3hrd:G 292 206 0.0386 0.1712 0.2427 0.002 3hrd:C
43 1n5w:C 287 94 0.0201 0.0906 0.2766 0.035 1n5w:F, 1n60:C, 1n60:F, 1n61:C, 1n61:F, 1n62:C, 1n62:F, 1n63:C, 1n63:F, 1zxi:C, 1zxi:F
44 2vos:A 448 56 0.0139 0.0402 0.3214 0.087 2vor:A
45 3dzd:A 368 51 0.0124 0.0435 0.3137 1.8 3dzd:B
46 8p5s:A 1087 72 0.0208 0.0248 0.3750 4.0 8p5x:A, 8p5x:B, 8p5x:C, 8p5x:D, 8p5x:E, 8p5x:F
47 8p5v:A 1121 72 0.0208 0.0241 0.3750 4.2 8p5t:A, 8p5t:B, 8p5t:C, 8p5t:D, 8p5t:E, 8p5t:F, 8p5u:A, 8p5u:B, 8p5u:C, 8p5u:D, 8p5u:E, 8p5u:F, 8p5v:B, 8p5v:E, 8p5v:D, 8p5v:C, 8p5v:F, 8p5w:A, 8p5w:B, 8p5w:C, 8p5w:D, 8p5w:E, 8p5w:F
48 1uqw:A 487 54 0.0139 0.0370 0.3333 4.3 1uqw:B
49 6xo2:A 294 95 0.0208 0.0918 0.2842 5.2 7mfj:AAA, 6pmu:A, 6pmu:B
50 3wqo:A 271 74 0.0162 0.0775 0.2838 5.6 3wqo:B
51 8ee6:A 1808 82 0.0170 0.0122 0.2683 6.0 8edw:A
52 5vb0:C 143 58 0.0147 0.1329 0.3276 7.0 5vb0:A, 5vb0:B, 5vb0:D, 5vb0:E, 5vb0:F, 5vb0:G, 5vb0:H, 5wep:A, 5wep:B
53 3e5z:A 290 50 0.0131 0.0586 0.3400 7.7 3e5z:B
54 7a5o:A 1205 60 0.0131 0.0141 0.2833 7.9 7a5o:B, 7a5o:C, 7a5o:D, 7a5o:E, 7a5o:F, 7a5o:G, 7a5o:H, 7a5o:I, 7a5o:J, 8ck2:A, 7pov:A, 7pov:B, 7pov:C, 7pov:D, 7pp6:A, 7pp6:B, 7pp6:C, 7pp6:D, 7pp6:E, 7pp6:G, 7prl:A, 6rbf:A, 6rbf:B, 6rbf:C, 6rbf:D, 6tm2:A, 6tm2:B, 6tm2:C, 6tm2:D, 6tm2:E, 6tm2:F, 6tm6:A
55 8qu1:N 173 72 0.0162 0.1214 0.2917 9.1 8pk0:N

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218