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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
AASSLDELVALCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDASVLTHRLVLHYSGHE
ATFADPMVDWTPPRYFNMMFQDLRGPRGGRGLLAYLRPETAQGIFVNFKNVLDATSRKLGFGIAQIGKAFRNEITPRNFI
FRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPESSAHYAKATVDILYRFPHGSLELEGIA
QRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIV
LKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKDG
TTRLKDTVTVRDRDTMEQIRLHVDELEGFLRERLRW

The query sequence (length=436) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1b76:A 442 442 1.0000 0.9864 0.9864 0.0 1ati:B, 1b76:B, 1ggm:A, 1ggm:B
2 8slg:B 447 474 0.4862 0.4743 0.4473 1.81e-133 8slf:B, 8u2q:B
3 8slg:A 429 456 0.4817 0.4895 0.4605 1.92e-133
4 8u2q:A 398 439 0.4656 0.5101 0.4624 5.74e-129 8slf:A
5 8u2p:A 401 436 0.4587 0.4988 0.4587 1.10e-125 8t5n:A
6 8slh:A 362 439 0.4197 0.5055 0.4169 3.27e-106
7 8sld:A 333 439 0.3830 0.5015 0.3804 3.89e-92
8 5e6m:B 506 489 0.3670 0.3162 0.3272 1.48e-71
9 5e6m:A 519 462 0.3532 0.2967 0.3333 5.13e-69 4kr2:A, 4kr3:A
10 2zt5:A 530 386 0.2798 0.2302 0.3161 2.82e-53 2zt6:A, 2zt7:A, 2zt8:A, 2zxf:A
11 2zt5:A 530 76 0.0826 0.0679 0.4737 5.46e-13 2zt6:A, 2zt7:A, 2zt8:A, 2zxf:A
12 4qei:A 562 536 0.3394 0.2633 0.2761 1.17e-40
13 8f6b:F 416 450 0.2867 0.3005 0.2778 7.22e-30 8f69:B, 8f69:A, 8f6b:E, 8f6b:A, 8f6b:C
14 8udk:B 369 436 0.2661 0.3144 0.2661 5.35e-26
15 1h4s:A 473 80 0.0688 0.0634 0.3750 0.002 1h4q:A, 1h4q:B, 1h4s:B, 1h4t:A, 1h4t:B, 1h4t:C, 1h4t:D, 1hc7:A, 1hc7:B, 1hc7:C, 1hc7:D
16 1nj1:A 463 118 0.0711 0.0670 0.2627 0.13 1nj2:A, 1nj5:A, 1nj6:A
17 5w75:C 387 90 0.0528 0.0594 0.2556 1.8 5w75:B, 5w75:D, 5w75:A
18 8p7b:B 455 210 0.1124 0.1077 0.2333 4.0 8p7b:D, 8p7c:B, 8p7c:D, 8p7d:B, 4rqe:C, 4rqf:A
19 3wqy:A 905 46 0.0321 0.0155 0.3043 4.1 3wqy:B, 3wqz:A, 3wqz:B, 2ztg:A
20 4l87:A 476 210 0.1124 0.1029 0.2333 4.3 8p7d:D, 4rqe:A, 4rqf:B
21 5la4:A 508 49 0.0482 0.0413 0.4286 7.1 8b0b:AAA, 8b0b:BBB, 8b0c:AAA, 8b0c:BBB, 8bac:AAA, 8bac:BBB, 8cqi:A, 8cqi:B, 8e07:A, 8e07:B, 8e08:A, 8e08:B, 5e8m:A, 5e97:A, 5e97:B, 5e98:A, 5e98:B, 5e9b:A, 5e9b:B, 5e9c:A, 5e9c:B, 8jyg:A, 8jyg:B, 5l9y:A, 5l9y:B, 5l9z:A, 5l9z:B, 5la7:A, 8ohq:AAA, 8ohq:BBB, 8ohr:AAA, 8ohr:BBB, 7pr7:A, 7pr7:B, 7pr8:A, 7pr8:B, 7prt:A, 7prt:B, 7yi7:A, 7yi7:B, 7yjc:A, 7yjc:B, 6zdm:AAA, 6zdm:BBB
22 9awk:A 402 64 0.0436 0.0473 0.2969 7.2 9avu:A, 9avu:C, 9avv:C, 9awj:A, 9awj:C, 9awk:C
23 3js4:A 207 37 0.0298 0.0628 0.3514 7.3 3js4:B, 3js4:C, 3js4:D
24 8w8j:A 572 144 0.0826 0.0629 0.2500 8.0 8w8j:B, 8w8l:A, 8w8l:B, 8w9i:A, 8w9i:B
25 2q3z:A 655 116 0.0573 0.0382 0.2155 8.6 9bc2:A, 3s3j:A
26 8gym:a9 340 34 0.0229 0.0294 0.2941 9.1 8b6f:A1, 8bqs:A1, 8gym:A9, 8gzu:a9, 8gzu:A9, 7tgh:A9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218