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Click <strong>PDB</strong> to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.</li> <li>Click <strong>Site #</strong> to view the binding site structure. Hover over <strong>Site #</strong> to view the binding residues.</li> <li>Hover over <strong>Ligand</strong> to view the full ligand name. Click <strong>Ligand</strong> to view the 2D diagram and other detail information of the ligand.</li> <li>Hover over <strong>EC number</strong> to view the full name of enzymatic activity.</li> <li>Hover over <strong>GO terms</strong> to view all GO terms. <li>Hover over <strong>UniProt</strong> to view the protein name.</li> <p></p> <form name="sform" action="qsearch.cgi"> Sort results by <select name="order" onchange="this.form.submit()"> <option value="pdbid" selected="selected">PDB ID</option> <option value="lig3">Ligand ID</option> <option value="uniprot">UniProt ID</option> <option value="reso">Resolution</option> <input type=hidden name=pdbid value='1e6y'> <input type=hidden name=lig3 value=''> <input type=hidden name=uniprot value=''> <input type=hidden name=ecn value=''> <input type=hidden name=got value=''> <input type=hidden name=ligname value=''> <input type=hidden name=pubmed value=''> <input type=hidden name=baff value=''> </form> <center> <a class='hover' href='?&page=1&order=pdbid&pdbid=1e6y'><<</a> <a class='hover' href='?&page=0&order=pdbid&pdbid=1e6y'><</a> 1 <a class='hover' href='?&page=2&order=pdbid&pdbid=1e6y'>></a> <a class='hover' href='?&page=last&order=pdbid&pdbid=1e6y'>>></a> <form name="pform" action="qsearch.cgi">Go to page <select name="page" onchange="this.form.submit()"> <option value="1" selected="selected">1</option> </select> <input type=hidden name=pdbid value='1e6y'> <input type=hidden name=lig3 value=''> <input type=hidden name=uniprot value=''> <input type=hidden name=ecn value=''> <input type=hidden name=got value=''> <input type=hidden name=ligname value=''> <input type=hidden name=pubmed value=''> </form></center><br> <table border="0" align=center width=100%> <tr BGCOLOR="#FF9900"> <th width=5% ALIGN=center><strong> # </strong></th> <th width=12% ALIGN=center><strong> PDB<br>(Resolution Å) </strong></th> <th width=5% ALIGN=center><strong> Site # </strong></th> <th width=10% ALIGN=center><strong> Ligand </strong> </th> <th width=10% ALIGN=center><strong> EC number </strong> </th> <th width=16% ALIGN=center><strong> GO terms </strong> </th> <th width=10% ALIGN=center><strong> UniProt </strong> </th> <th width=10% ALIGN=center><strong> PubMed </strong> </th> <th width=22% ALIGN=center><strong> Binding<br>affinity</strong> </th> </tr><tr ALIGN=center> <tr ALIGN=center> <td>1</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:A</a> (1.6)</span></td> <td><span title="A1158 V1159 V1160 Q1161 M1164 Q1244 M1247 A1257"><a href="pdb.cgi?pdb=1e6y&chain=A&bs=BS01" target=_blank>BS01</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>2</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:A</a> (1.6)</span></td> <td><span title="R1284 M1337 F1343 F1463 M1500 N1501"><a href="pdb.cgi?pdb=1e6y&chain=A&bs=BS02" target=_blank>BS02</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=TP7" target=_blank><span title="ZINC000003869535">TP7</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>3</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:A</a> (1.6)</span></td> <td><span title="Y1346 F1463 F1464"><a href="pdb.cgi?pdb=1e6y&chain=A&bs=BS03" target=_blank>BS03</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=COM" target=_blank><span title="ZINC000003831040">COM</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>4</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:A</a> (1.6)</span></td> <td><span title="V1341 G1342 F1343 T1344 Q1345 Y1346 F1463"><a href="pdb.cgi?pdb=1e6y&chain=A&bs=BS04" target=_blank>BS04</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>5</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:A</a> (1.6)</span></td> <td><span title="R1239 K1270 H1271"><a href="pdb.cgi?pdb=1e6y&chain=A&bs=BS05" target=_blank>BS05</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=TP7" target=_blank><span title="ZINC000003869535">TP7</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>6</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:B</a> (1.6)</span></td> <td><span title="F2359 F2360 Y2365 G2367 H2377"><a href="pdb.cgi?pdb=1e6y&chain=B&bs=BS01" target=_blank>BS01</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=TP7" target=_blank><span title="ZINC000003869535">TP7</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07955" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRB_METBF Methyl-coenzyme M reductase subunit beta (Gene Name=mcrB)"><a href=https://uniprot.org/uniprot/P07955 target=_blank>P07955</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>7</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:B</a> (1.6)</span></td> <td><span title="F2359 Y2365"><a href="pdb.cgi?pdb=1e6y&chain=B&bs=BS02" target=_blank>BS02</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=COM" target=_blank><span title="ZINC000003831040">COM</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07955" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRB_METBF Methyl-coenzyme M reductase subunit beta (Gene Name=mcrB)"><a href=https://uniprot.org/uniprot/P07955 target=_blank>P07955</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>8</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:B</a> (1.6)</span></td> <td><span title="S2363 I2364 Y2365"><a href="pdb.cgi?pdb=1e6y&chain=B&bs=BS03" target=_blank>BS03</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07955" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRB_METBF Methyl-coenzyme M reductase subunit beta (Gene Name=mcrB)"><a href=https://uniprot.org/uniprot/P07955 target=_blank>P07955</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>9</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:C</a> (1.6)</span></td> <td><span title="L3118 S3119 G3120 A3154 T3155 V3156 H3159"><a href="pdb.cgi?pdb=1e6y&chain=C&bs=BS01" target=_blank>BS01</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07964" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRG_METBF Methyl-coenzyme M reductase subunit gamma (Gene Name=mcrG)"><a href=https://uniprot.org/uniprot/P07964 target=_blank>P07964</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>10</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:D</a> (1.6)</span></td> <td><span title="G4340 V4341 G4342 F4343 T4344 Q4345 Y4346 F4416 G4462 F4463"><a href="pdb.cgi?pdb=1e6y&chain=D&bs=BS01" target=_blank>BS01</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>11</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:D</a> (1.6)</span></td> <td><span title="R4239 K4270 H4271"><a href="pdb.cgi?pdb=1e6y&chain=D&bs=BS02" target=_blank>BS02</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=TP7" target=_blank><span title="ZINC000003869535">TP7</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>12</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:D</a> (1.6)</span></td> <td><span title="A4158 V4159 V4160 Q4161 M4164 Q4244 M4247 A4257"><a href="pdb.cgi?pdb=1e6y&chain=D&bs=BS03" target=_blank>BS03</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>13</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:D</a> (1.6)</span></td> <td><span title="R4284 M4337 F4343 F4463 M4500 N4501 V4502"><a href="pdb.cgi?pdb=1e6y&chain=D&bs=BS04" target=_blank>BS04</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=TP7" target=_blank><span title="ZINC000003869535">TP7</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>14</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:D</a> (1.6)</span></td> <td><span title="Y4346 F4463 F4464"><a href="pdb.cgi?pdb=1e6y&chain=D&bs=BS05" target=_blank>BS05</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=COM" target=_blank><span title="ZINC000003831040">COM</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07962" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0046872 (F) metal ion binding GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRA_METBF Methyl-coenzyme M reductase subunit alpha (Gene Name=mcrA)"><a href=https://uniprot.org/uniprot/P07962 target=_blank>P07962</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>15</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:E</a> (1.6)</span></td> <td><span title="S5363 I5364 Y5365"><a href="pdb.cgi?pdb=1e6y&chain=E&bs=BS01" target=_blank>BS01</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07955" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRB_METBF Methyl-coenzyme M reductase subunit beta (Gene Name=mcrB)"><a href=https://uniprot.org/uniprot/P07955 target=_blank>P07955</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>16</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:E</a> (1.6)</span></td> <td><span title="F5359 F5360 Y5365 G5367 H5377"><a href="pdb.cgi?pdb=1e6y&chain=E&bs=BS02" target=_blank>BS02</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=TP7" target=_blank><span title="ZINC000003869535">TP7</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07955" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRB_METBF Methyl-coenzyme M reductase subunit beta (Gene Name=mcrB)"><a href=https://uniprot.org/uniprot/P07955 target=_blank>P07955</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr ALIGN=center> <td>17</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:E</a> (1.6)</span></td> <td><span title="F5359 Y5365"><a href="pdb.cgi?pdb=1e6y&chain=E&bs=BS03" target=_blank>BS03</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=COM" target=_blank><span title="ZINC000003831040">COM</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07955" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRB_METBF Methyl-coenzyme M reductase subunit beta (Gene Name=mcrB)"><a href=https://uniprot.org/uniprot/P07955 target=_blank>P07955</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> <tr BGCOLOR="#DEDEDE" ALIGN=center> <td>18</td> <td><span title="Comparison of Three Methyl-Coenzyme M Reductases from Phylogenetically Distant Organisms: Unusual Amino Acid Modification, Conservation and Adaptation "><a href="https://rcsb.org/structure/1e6y" target=_blank>1e6y:F</a> (1.6)</span></td> <td><span title="L6118 S6119 G6120 A6154 T6155 V6156 H6157 H6159"><a href="pdb.cgi?pdb=1e6y&chain=F&bs=BS01" target=_blank>BS01</span></td> <td style="word-wrap: break-word"><a href="sym.cgi?code=F43" target=_blank><span title="">F43</span></a></td> <td><a href=https://enzyme.expasy.org/EC/2.8.4.1 target=_blank><span title="coenzyme-B sulfoethylthiotransferase.">2.8.4.1</span></a></td> <td><a href="https://ebi.ac.uk/QuickGO/annotations?geneProductId=P07964" target=_blank><span title="GO:0005737 (C) cytoplasm GO:0015948 (P) methanogenesis GO:0016740 (F) transferase activity GO:0050524 (F) coenzyme-B sulfoethylthiotransferase activity">GO:0005737 ...</span></a></td> <td><span title="MCRG_METBF Methyl-coenzyme M reductase subunit gamma (Gene Name=mcrG)"><a href=https://uniprot.org/uniprot/P07964 target=_blank>P07964</a></span></td> <td><a href=https://pubmed.ncbi.nlm.nih.gov/11023796 target=_blank>11023796</a></td> <td></td> </tr> </table> </div> <div> <hr width=30% align=left> <b>Reference:</b> <ul> <li> Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. <i>BioLiP2: an updated structure database for biologically relevent ligand-protein interactions</i>, Nucleic Acids Research, gkad630 (2023)(<a href=/papers/2023_9.pdf>download the PDF file</a>). </li> <li> Jianyi Yang, Ambrish Roy, and Yang Zhang. <i>BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions</i>, Nucleic Acids Research, 41: D1096-D1103 (2013) (<a href=/papers/2013_1.pdf>download the PDF file</a>). </li> </ul> <p> <p> </div> </div> </div> <script> function submitQsearch(token) { document.getElementById('qsearchForm').submit(); } </script> <script> function submitSsearch(token) { document.getElementById('ssearchForm').submit(); } </script> <script> function submitFsearch(token) { document.getElementById('fsearchForm').submit(); } </script> <script 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