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BioLiP
Download all results in tab-seperated text for 903398 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    60601 1ww6:B (2.2) BS02 GAL 3.1.21.- GO:0004518 ... Q6WY08 16051274
    60602 1ww6:C (2.2) BS01 BGC 3.1.21.- GO:0004518 ... Q6WY08 16051274
    60603 1ww6:C (2.2) BS02 GAL 3.1.21.- GO:0004518 ... Q6WY08 16051274
    60604 1ww6:D (2.2) BS01 GAL 3.1.21.- GO:0004518 ... Q6WY08 16051274
    60605 1ww7:A (1.9) BS01 SO4 3.1.21.- GO:0004518 ... Q6WY08 16051274
    60606 1ww7:B (1.9) BS01 SO4 3.1.21.- GO:0004518 ... Q6WY08 16051274
    60607 1ww7:C (1.9) BS01 SO4 3.1.21.- GO:0004518 ... Q6WY08 16051274
    60608 1ww9:A (1.95) BS01 FE2 1.14.12.- GO:0046872 ... Q84II6 16005887
    60609 1ww9:A (1.95) BS02 FES 1.14.12.- GO:0046872 ... Q84II6 16005887
    60610 1wwd:A (-1.00) BS01 rna ? GO:0003676 ... P03332 15751950 PDBbind: Kd=250nM
    60611 1wwd:A (-1.00) BS02 ZN ? GO:0003676 ... P03332 15751950
    60612 1wwe:A (-1.00) BS01 rna ? GO:0003676 ... P03332 15751950 PDBbind: Kd=170nM
    60613 1wwe:A (-1.00) BS02 ZN ? GO:0003676 ... P03332 15751950
    60614 1wwf:A (-1.00) BS01 rna ? GO:0003676 ... P03332 15751950 PDBbind: Kd=94nM
    60615 1wwf:A (-1.00) BS02 ZN ? GO:0003676 ... P03332 15751950
    60616 1wwg:A (-1.00) BS01 rna ? GO:0003676 ... P03332 15751950 PDBbind: Kd=95nM
    60617 1wwg:A (-1.00) BS02 ZN ? GO:0003676 ... P03332 15751950
    60618 1wwk:A (1.9) BS01 NAD 1.1.1.95 GO:0000166 ... O50095 N/A
    60619 1wwk:B (1.9) BS01 NAD 1.1.1.95 GO:0000166 ... O50095 N/A
    60620 1wwr:A (1.8) BS01 ZN 3.5.4.33 GO:0002100 ... O67050 15677468
    60621 1wwr:B (1.8) BS01 ZN 3.5.4.33 GO:0002100 ... O67050 15677468
    60622 1wwr:C (1.8) BS01 ZN 3.5.4.33 GO:0002100 ... O67050 15677468
    60623 1wwr:D (1.8) BS01 ZN 3.5.4.33 GO:0002100 ... O67050 15677468
    60624 1wwz:A (1.75) BS01 ACO ? GO:0016747 ... O59596 N/A
    60625 1wwz:B (1.75) BS01 ACO ? GO:0016747 ... O59596 N/A
    60626 1wx2:A (1.8) BS01 CU 1.14.18.1 GO:0016491 ... Q83WS2 16436386
    60627 1wx2:A (1.8) BS02 CU 1.14.18.1 GO:0016491 ... Q83WS2 16436386
    60628 1wx2:A (1.8) BS03 PER 1.14.18.1 GO:0016491 ... Q83WS2 16436386
    60629 1wx4:A (1.5) BS01 CU 1.14.18.1 GO:0016491 ... Q83WS2 16436386
    60630 1wx4:A (1.5) BS02 CU 1.14.18.1 GO:0016491 ... Q83WS2 16436386
    60631 1wx4:A (1.5) BS03 PER 1.14.18.1 GO:0016491 ... Q83WS2 16436386
    60632 1wxe:A (1.9) BS01 MG 6.3.1.5 GO:0000287 ... P18843 15699042
    60633 1wxe:A (1.9) BS02 AMP 6.3.1.5 GO:0000287 ... P18843 15699042
    60634 1wxe:A (1.9) BS03 AMP 6.3.1.5 GO:0000287 ... P18843 15699042
    60635 1wxg:A (1.9) BS01 MG 6.3.1.5 GO:0000287 ... P18843 15699042
    60636 1wxg:A (1.9) BS02 DND 6.3.1.5 GO:0000287 ... P18843 15699042
    60637 1wxh:A (1.9) BS01 NAD 6.3.1.5 GO:0000287 ... P18843 15699042
    60638 1wxi:A (1.7) BS01 MG 6.3.1.5 GO:0000287 ... P18843 15699042
    60639 1wxi:A (1.7) BS02 AMP 6.3.1.5 GO:0000287 ... P18843 15699042
    60640 1wxi:A (1.7) BS03 AMP 6.3.1.5 GO:0000287 ... P18843 15699042
    60641 1wxo:A (1.88) BS01 ZN ? GO:0000166 ... O58307 16087889
    60642 1wxo:B (1.88) BS01 ZN ? GO:0000166 ... O58307 16087889
    60643 1wxo:C (1.88) BS01 ZN ? GO:0000166 ... O58307 16087889
    60644 1wxy:A (2.5) BS01 ZN 3.5.4.4 GO:0004000 ... P56658 16060665
    60645 1wxy:A (2.5) BS02 FRK 3.5.4.4 GO:0004000 ... P56658 16060665
    60646 1wxz:A (2.8) BS01 ZN 3.5.4.4 GO:0004000 ... P56658 16033254
    60647 1wxz:A (2.8) BS02 FRL 3.5.4.4 GO:0004000 ... P56658 16033254 PDBbind: -logKd/Ki=8.07, IC50=8.6nM
    60648 1wy2:A (1.7) BS01 ZN 3.4.13.9 GO:0005737 ... O58885 N/A
    60649 1wy2:A (1.7) BS02 ZN 3.4.13.9 GO:0005737 ... O58885 N/A
    60650 1wy2:B (1.7) BS01 ZN 3.4.13.9 GO:0005737 ... O58885 N/A
    60651 1wy2:B (1.7) BS02 ZN 3.4.13.9 GO:0005737 ... O58885 N/A
    60652 1wy7:A (2.2) BS01 SAH 2.1.1.- GO:0003676 ... O59611 16245322
    60653 1wy7:B (2.2) BS01 SAH 2.1.1.- GO:0003676 ... O59611 16245322
    60654 1wy7:C (2.2) BS01 SAH 2.1.1.- GO:0003676 ... O59611 16245322
    60655 1wy7:D (2.2) BS01 SAH 2.1.1.- GO:0003676 ... O59611 16245322
    60656 1wy9:A (2.1) BS01 CA ? GO:0001726 ... O70200 17011575
    60657 1wyg:A (2.6) BS01 CA 1.17.1.4
    1.17.3.2
    GO:0000255 ... P22985 15878860
    60658 1wyg:A (2.6) BS02 FES 1.17.1.4
    1.17.3.2
    GO:0000255 ... P22985 15878860
    60659 1wyg:A (2.6) BS03 FES 1.17.1.4
    1.17.3.2
    GO:0000255 ... P22985 15878860
    60660 1wyg:A (2.6) BS04 FAD 1.17.1.4
    1.17.3.2
    GO:0000255 ... P22985 15878860
    60661 1wyh:A (-1.00) BS01 ZN ? N/A Q13643 N/A
    60662 1wyh:A (-1.00) BS02 ZN ? N/A Q13643 N/A
    60663 1wys:A (-1.00) BS01 ZN ? GO:0008270 ... Q8BFR6 N/A
    60664 1wys:A (-1.00) BS02 ZN ? GO:0008270 ... Q8BFR6 N/A
    60665 1wyu:A (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60666 1wyu:B (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60667 1wyu:C (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60668 1wyu:D (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60669 1wyu:E (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60670 1wyu:F (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60671 1wyu:G (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60672 1wyu:H (2.1) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60673 1wyv:A (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60674 1wyv:A (2.4) BS02 AOA 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60675 1wyv:B (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60676 1wyv:C (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60677 1wyv:C (2.4) BS02 AOA 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60678 1wyv:D (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60679 1wyv:E (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60680 1wyv:E (2.4) BS02 AOA 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60681 1wyv:F (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60682 1wyv:G (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60683 1wyv:G (2.4) BS02 AOA 1.4.4.2 GO:0004375 ... Q5SKW8 15791207
    60684 1wyv:H (2.4) BS01 PLP 1.4.4.2 GO:0004375 ... Q5SKW7 15791207
    60685 1wyw:A (2.1) BS01 MG 3.2.2.29 GO:0000700 ... Q13569 15959518
    60686 1wyw:A (2.1) BS02 MG 3.2.2.29 GO:0000700 ... Q13569 15959518
    60687 1wz1:H (1.85) BS01 DNS N/A N/A N/A 16019026
    60688 1wz2:A (3.21) BS01 rna 6.1.1.4 GO:0000166 ... O58698 N/A
    60689 1wz2:B (3.21) BS01 rna 6.1.1.4 GO:0000166 ... O58698 N/A
    60690 1wza:A (1.6) BS01 CA 3.2.1.1 GO:0004556 ... Q8GPL8 16647060
    60691 1wza:A (1.6) BS02 CA 3.2.1.1 GO:0004556 ... Q8GPL8 16647060
    60692 1wzb:A (1.5) BS01 peptide ? N/A Q80BK4 16313184
    60693 1wzb:A (1.5) BS02 peptide ? N/A Q80BK4 16313184
    60694 1wzc:A (1.9) BS01 MG 3.1.3.70 GO:0000287 ... O58690 19018103
    60695 1wzc:A (1.9) BS02 PO4 3.1.3.70 GO:0000287 ... O58690 19018103
    60696 1wzc:B (1.9) BS01 MG 3.1.3.70 GO:0000287 ... O58690 19018103
    60697 1wzc:B (1.9) BS02 PO4 3.1.3.70 GO:0000287 ... O58690 19018103
    60698 1wzd:A (1.35) BS01 YOK 1.14.14.18 GO:0004392 ... Q54AI1 16769893
    60699 1wzd:B (1.35) BS01 YOK 1.14.14.18 GO:0004392 ... Q54AI1 16769893
    60700 1wze:A (2.0) BS01 NAD 1.1.1.37 GO:0003824 ... P10584 N/A
    60701 1wze:B (2.0) BS01 NAD 1.1.1.37 GO:0003824 ... P10584 N/A
    60702 1wzf:A (1.85) BS01 YOL 1.14.14.18 GO:0004392 ... P71119 16769893
    60703 1wzf:B (1.85) BS01 YOL 1.14.14.18 GO:0004392 ... P71119 16769893
    60704 1wzg:A (1.75) BS01 YOM 1.14.14.18 GO:0004392 ... P71119 16769893
    60705 1wzg:B (1.75) BS01 YOM 1.14.14.18 GO:0004392 ... P71119 16769893
    60706 1wzi:A (2.0) BS01 NDP 1.1.1.37 GO:0003824 ... P10584 N/A
    60707 1wzi:B (2.0) BS01 NDP 1.1.1.37 GO:0003824 ... P10584 N/A
    60708 1wzk:A (2.3) BS01 CA 3.2.1.135 GO:0004553 ... Q08751 N/A
    60709 1wzk:B (2.3) BS01 CA 3.2.1.135 GO:0004553 ... Q08751 N/A
    60710 1wzl:A (2.0) BS01 CA 3.2.1.135 GO:0004553 ... Q08751 N/A
    60711 1wzl:B (2.0) BS01 CA 3.2.1.135 GO:0004553 ... Q08751 N/A
    60712 1wzm:A (3.2) BS01 CA 3.2.1.135 GO:0004553 ... Q08751 N/A
    60713 1wzm:B (3.2) BS01 CA 3.2.1.135 GO:0004553 ... Q08751 N/A
    60714 1wzn:A (1.9) BS01 SAH 2.1.1.- GO:0016740 ... O59000 N/A
    60715 1wzn:B (1.9) BS01 SAH 2.1.1.- GO:0016740 ... O59000 N/A
    60716 1wzn:C (1.9) BS01 SAH 2.1.1.- GO:0016740 ... O59000 N/A
    60717 1wzy:A (2.5) BS01 F29 2.7.11.24 GO:0000165 ... P28482 16242327 MOAD: ic50=0.56uM
    PDBbind: -logKd/Ki=6.25, IC50=0.56uM
    BindingDB: IC50=560nM
    60718 1x01:A (2.0) BS01 ATP 6.3.4.15 GO:0004077 ... O57883 18372281
    60719 1x01:B (2.0) BS01 ATP 6.3.4.15 GO:0004077 ... O57883 18372281
    60720 1x02:A (-1.00) BS01 CA ? GO:0005102 ... P0DP33 16511487
    60721 1x02:A (-1.00) BS02 CA ? GO:0005102 ... P0DP33 16511487
    60722 1x02:A (-1.00) BS03 CA ? GO:0005102 ... P0DP33 16511487
    60723 1x02:A (-1.00) BS04 CA ? GO:0005102 ... P0DP33 16511487
    60724 1x06:A (1.9) BS01 PO4 2.5.1.31 GO:0000287 ... P60472 15788389
    60725 1x06:A (1.9) BS02 FPS 2.5.1.31 GO:0000287 ... P60472 15788389
    60726 1x06:A (1.9) BS03 FPS 2.5.1.31 GO:0000287 ... P60472 15788389
    60727 1x07:A (2.2) BS01 PO4 2.5.1.31 GO:0000287 ... P60472 15788389
    60728 1x07:A (2.2) BS02 IPE 2.5.1.31 GO:0000287 ... P60472 15788389 MOAD: Kd=520uM
    PDBbind: -logKd/Ki=3.28, Kd=520uM
    60729 1x08:A (1.9) BS01 FPS 2.5.1.31 GO:0000287 ... P60472 15788389
    60730 1x08:A (1.9) BS02 FPS 2.5.1.31 GO:0000287 ... P60472 15788389
    60731 1x09:A (1.87) BS01 IPE 2.5.1.31 GO:0000287 ... P60472 15788389 MOAD: Kd=520uM
    60732 1x09:A (1.87) BS02 IPE 2.5.1.31 GO:0000287 ... P60472 15788389 MOAD: Kd=520uM
    60733 1x0f:A (-1.00) BS01 dna ? GO:0003676 ... Q14103 15734733
    60734 1x0g:A (2.5) BS01 FES ? GO:0005737 ... Q8DLM0 16730357
    60735 1x0g:B (2.5) BS01 FES ? GO:0005737 ... Q8DLM0 16730357
    60736 1x0g:C (2.5) BS01 FES ? GO:0005737 ... Q8DLM0 16730357
    60737 1x0i:1 (2.3) BS01 SO4 ? GO:0005216 ... P02945 16023672
    60738 1x0i:1 (2.3) BS02 RET ? GO:0005216 ... P02945 16023672
    60739 1x0k:1 (2.6) BS01 RET ? GO:0005216 ... P02945 16023672
    60740 1x0n:A (-1.00) BS01 DTF ? N/A P62993 N/A PDBbind: -logKd/Ki=7.70, IC50=20nM
    BindingDB: IC50=20nM
    60741 1x0p:A (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60742 1x0p:B (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60743 1x0p:C (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60744 1x0p:D (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60745 1x0p:E (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60746 1x0p:F (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60747 1x0p:G (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60748 1x0p:H (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60749 1x0p:I (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60750 1x0p:J (2.0) BS01 FAD ? GO:0000166 ... Q8DMN3 15876364
    60751 1x0s:A (2.5) BS01 RET ? GO:0005216 ... P02945 16084526
    60752 1x0t:A (1.6) BS01 ZN 3.1.26.5 GO:0001682 ... O59248 16142906
    60753 1x0v:A (2.3) BS01 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60754 1x0v:A (2.3) BS02 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60755 1x0v:A (2.3) BS03 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60756 1x0v:A (2.3) BS04 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60757 1x0v:A (2.3) BS05 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60758 1x0v:B (2.3) BS01 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60759 1x0v:B (2.3) BS02 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60760 1x0v:B (2.3) BS03 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60761 1x0x:A (2.75) BS01 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60762 1x0x:A (2.75) BS02 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60763 1x0x:A (2.75) BS03 SO4 1.1.1.8 GO:0004368 ... P21695 16460752
    60764 1x0x:A (2.75) BS04 NAD 1.1.1.8 GO:0004368 ... P21695 16460752
    60765 1x11:A (2.5) BS01 peptide ? N/A Q02410 9321393
    60766 1x11:B (2.5) BS01 peptide ? N/A Q02410 9321393
    60767 1x11:B (2.5) BS02 peptide ? N/A Q02410 9321393
    60768 1x14:B (1.94) BS01 NAD 7.1.1.1 GO:0016491 ... P07001 16083909
    60769 1x15:B (2.04) BS01 NAD 7.1.1.1 GO:0016491 ... P07001 16083909
    60770 1x1a:A (2.6) BS01 SAM 2.1.1.333 GO:0008168 ... Q8KGE0 16797589
    60771 1x1b:A (2.6) BS01 SAH 2.1.1.333 GO:0008168 ... Q8KGE0 16797589
    60772 1x1c:A (2.85) BS01 ZN 2.1.1.333 GO:0008168 ... Q8KGE0 16797589
    60773 1x1c:A (2.85) BS02 SAH 2.1.1.333 GO:0008168 ... Q8KGE0 16797589
    60774 1x1d:A (2.7) BS01 SAH 2.1.1.333 GO:0008168 ... Q8KGE0 16797589
    60775 1x1i:A (1.8) BS01 46M 4.2.2.12 GO:0003824 ... Q9AQS0 15979090
    60776 1x1j:A (2.1) BS01 46D 4.2.2.12 GO:0003824 ... Q9AQS0 15979090
    60777 1x1j:A (2.1) BS02 CA 4.2.2.12 GO:0003824 ... Q9AQS0 15979090
    60778 1x1r:A (1.3) BS01 GDP 3.6.5.2 GO:0003924 ... O08989 15994326
    60779 1x1s:A (2.2) BS01 GNP 3.6.5.2 GO:0003924 ... O08989 15994326
    60780 1x1t:A (1.52) BS01 CAC 1.1.1.30 GO:0000166 ... Q5KST5 16325199
    60781 1x1t:A (1.52) BS02 NAD 1.1.1.30 GO:0000166 ... Q5KST5 16325199
    60782 1x1v:A (2.45) BS01 MMA ? GO:0030246 ... Q8L5H4 15958419
    60783 1x1v:A (2.45) BS02 MMA ? GO:0030246 ... Q8L5H4 15958419
    60784 1x1v:A (2.45) BS03 MMA ? GO:0030246 ... Q8L5H4 15958419
    60785 1x1v:A (2.45) BS04 ZN ? GO:0030246 ... Q8L5H4 15958419
    60786 1x1v:B (2.45) BS01 MMA ? GO:0030246 ... Q8L5H4 15958419
    60787 1x1v:B (2.45) BS02 MMA ? GO:0030246 ... Q8L5H4 15958419
    60788 1x1v:B (2.45) BS03 ZN ? GO:0030246 ... Q8L5H4 15958419
    60789 1x1z:A (1.45) BS01 BMP 4.1.1.23 GO:0004590 ... O26232 16248642 MOAD: Ki=8.8pM
    PDBbind: -logKd/Ki=11.06, Ki=8.8pM
    60790 1x1z:A (1.45) BS02 BMP 4.1.1.23 GO:0004590 ... O26232 16248642 MOAD: Ki=8.8pM
    PDBbind: -logKd/Ki=11.06, Ki=8.8pM
    60791 1x1z:B (1.45) BS01 BMP 4.1.1.23 GO:0004590 ... O26232 16248642 PDBbind: -logKd/Ki=11.06, Ki=8.8pM
    60792 1x1z:B (1.45) BS02 BMP 4.1.1.23 GO:0004590 ... O26232 16248642 PDBbind: -logKd/Ki=11.06, Ki=8.8pM
    60793 1x27:A (2.7) BS01 peptide 2.7.10.2 N/A P06239 16245368
    60794 1x27:A (2.7) BS02 peptide 2.7.10.2 N/A P06239 16245368
    60795 1x27:B (2.7) BS01 peptide 2.7.10.2 N/A P06239 16245368
    60796 1x27:C (2.7) BS01 peptide 2.7.10.2 N/A P06239 16245368
    60797 1x27:D (2.7) BS01 peptide 2.7.10.2 N/A P06239 16245368
    60798 1x27:E (2.7) BS01 peptide 2.7.10.2 N/A P06239 16245368
    60799 1x27:F (2.7) BS01 peptide 2.7.10.2 N/A P06239 16245368
    60800 1x28:A (2.4) BS01 PGU 2.6.1.1 GO:0003824 ... P00509 15938611

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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