8k23 A 3.75 BS01 dna R 0 M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870 M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870 0016787,0046872,0051607 F1D5V9 15 ~ 45 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 a 3.75 BS01 dna V 0 K10 Q11 K10 Q11 0016787,0046872,0051607 F1D5V9 1 ~ 21 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 a 3.75 BS02 dna r 0 M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870 M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870 0016787,0046872,0051607 F1D5V9 15 ~ 45 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 A 3.75 BS02 dna U 0 K10 Q11 K10 Q11 0016787,0046872,0051607 F1D5V9 1 ~ 21 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 a 3.75 BS03 MN a 1 D112 K115 H136 H186 H187 D112 K115 H136 H186 H187 0016787,0046872,0051607 F1D5V9 1000 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 A 3.75 BS03 MN A 1 D112 K115 H136 H186 H187 D112 K115 H136 H186 H187 0016787,0046872,0051607 F1D5V9 1000 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 a 3.75 BS04 MN a 2 H111 D112 D280 H312 H111 D112 D280 H312 0016787,0046872,0051607 F1D5V9 1001 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 A 3.75 BS04 MN A 2 H111 D112 D280 H312 H111 D112 D280 H312 0016787,0046872,0051607 F1D5V9 1001 MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLINVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLKQGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKGNDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRATKTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKLLATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLDECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFAWQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMVSLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQTSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYVRCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISNIFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRFVNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLIRTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLNRKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQCAGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKNMLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVFVGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKWQGENGSITVPEYLLDKTICYNDFYGGYEN 8k23 b 3.75 BS01 rna p 0 L101 P102 Q103 I104 Y105 Y112 P117 L101 P102 Q103 I104 Y105 Y112 P117 F1D5V8 -7 ~ 52 MIKEMIEDFISKGGLIFTHSGRYTNTNNSCFIFNKNDIGVDTKVDMYTPKSAGIKNEEGENLWQVLNKANMFYRIYSGELGEELQYLLKSCCTAKEDVTTLPQIYFKNGEGYDILVPIGNAHNLISGTEYLWEHKYYNTFTQKLGGSNPQNCTHACNKMRGGFKQFNCTPPQVEDNY 8k23 B 3.75 BS01 rna P 0 L101 P102 Q103 I104 Y105 Y112 P117 L101 P102 Q103 I104 Y105 Y112 P117 F1D5V8 -7 ~ 52 MIKEMIEDFISKGGLIFTHSGRYTNTNNSCFIFNKNDIGVDTKVDMYTPKSAGIKNEEGENLWQVLNKANMFYRIYSGELGEELQYLLKSCCTAKEDVTTLPQIYFKNGEGYDILVPIGNAHNLISGTEYLWEHKYYNTFTQKLGGSNPQNCTHACNKMRGGFKQFNCTPPQVEDNY 8k23 b 3.75 BS02 dna q 0 R22 T26 N27 K50 G146 S147 N148 Q150 N151 R22 T26 N27 K50 G146 S147 N148 Q150 N151 F1D5V8 18 ~ 60 MIKEMIEDFISKGGLIFTHSGRYTNTNNSCFIFNKNDIGVDTKVDMYTPKSAGIKNEEGENLWQVLNKANMFYRIYSGELGEELQYLLKSCCTAKEDVTTLPQIYFKNGEGYDILVPIGNAHNLISGTEYLWEHKYYNTFTQKLGGSNPQNCTHACNKMRGGFKQFNCTPPQVEDNY 8k23 B 3.75 BS02 dna Q 0 R22 T26 N27 K50 G146 S147 N148 Q150 N151 R22 T26 N27 K50 G146 S147 N148 Q150 N151 F1D5V8 18 ~ 60 MIKEMIEDFISKGGLIFTHSGRYTNTNNSCFIFNKNDIGVDTKVDMYTPKSAGIKNEEGENLWQVLNKANMFYRIYSGELGEELQYLLKSCCTAKEDVTTLPQIYFKNGEGYDILVPIGNAHNLISGTEYLWEHKYYNTFTQKLGGSNPQNCTHACNKMRGGFKQFNCTPPQVEDNY 8k23 b 3.75 BS03 dna r 0 K50 A52 G53 K55 W132 Y137 N138 T141 Q150 N157 K158 R160 K164 T169 P170 P171 E174 Y177 K50 A52 G53 K55 W132 Y137 N138 T141 Q150 N157 K158 R160 K164 T169 P170 P171 E174 Y177 F1D5V8 15 ~ 45 MIKEMIEDFISKGGLIFTHSGRYTNTNNSCFIFNKNDIGVDTKVDMYTPKSAGIKNEEGENLWQVLNKANMFYRIYSGELGEELQYLLKSCCTAKEDVTTLPQIYFKNGEGYDILVPIGNAHNLISGTEYLWEHKYYNTFTQKLGGSNPQNCTHACNKMRGGFKQFNCTPPQVEDNY 8k23 B 3.75 BS03 dna R 0 K50 A52 G53 K55 W132 Y137 N138 T141 Q150 N157 K158 R160 K164 T169 P170 P171 E174 Y177 K50 A52 G53 K55 W132 Y137 N138 T141 Q150 N157 K158 R160 K164 T169 P170 P171 E174 Y177 F1D5V8 15 ~ 45 MIKEMIEDFISKGGLIFTHSGRYTNTNNSCFIFNKNDIGVDTKVDMYTPKSAGIKNEEGENLWQVLNKANMFYRIYSGELGEELQYLLKSCCTAKEDVTTLPQIYFKNGEGYDILVPIGNAHNLISGTEYLWEHKYYNTFTQKLGGSNPQNCTHACNKMRGGFKQFNCTPPQVEDNY 8k23 c 3.75 BS01 rna p 0 N16 K18 S19 S20 T31 G34 E37 T38 I41 K42 T69 K70 F71 A72 Q74 K91 R125 G128 Y186 R199 P210 N16 K18 S19 S20 T31 G34 E37 T38 I41 K42 T69 K70 F71 A72 Q74 K91 R125 G128 Y186 R199 P210 F1D5V7 -7 ~ 52 MRKFIIVKNVKVDGINAKSSDITVGMPPATTFCGLGETMSIKTGIVVKAVSYGSVKFEVRGSRFNTSVTKFAWQDRGNGGKANNNSPIQPKPLADGVFTLCFEVEWEDCAEVLVDKVTNFINTARIAGGTIASFNKPFVKVAKDAEELASVKNAMMPCYVVVDCGVEVNIFEDAVNRKLQPMVNGYKKLEKIVDNKHMRDKFTPAYLATPTYTMIGYKMVSNVDNFDQALWQYGENTKVKTIGGIYN 8k23 C 3.75 BS01 rna P 0 N16 K18 S19 S20 T31 G34 E37 T38 I41 K42 T69 K70 F71 A72 Q74 K91 R125 G128 Y186 R199 P210 N16 K18 S19 S20 T31 G34 E37 T38 I41 K42 T69 K70 F71 A72 Q74 K91 R125 G128 Y186 R199 P210 F1D5V7 -7 ~ 52 MRKFIIVKNVKVDGINAKSSDITVGMPPATTFCGLGETMSIKTGIVVKAVSYGSVKFEVRGSRFNTSVTKFAWQDRGNGGKANNNSPIQPKPLADGVFTLCFEVEWEDCAEVLVDKVTNFINTARIAGGTIASFNKPFVKVAKDAEELASVKNAMMPCYVVVDCGVEVNIFEDAVNRKLQPMVNGYKKLEKIVDNKHMRDKFTPAYLATPTYTMIGYKMVSNVDNFDQALWQYGENTKVKTIGGIYN 8k23 c 3.75 BS02 dna q 0 N85 P87 I88 N85 P87 I88 F1D5V7 18 ~ 60 MRKFIIVKNVKVDGINAKSSDITVGMPPATTFCGLGETMSIKTGIVVKAVSYGSVKFEVRGSRFNTSVTKFAWQDRGNGGKANNNSPIQPKPLADGVFTLCFEVEWEDCAEVLVDKVTNFINTARIAGGTIASFNKPFVKVAKDAEELASVKNAMMPCYVVVDCGVEVNIFEDAVNRKLQPMVNGYKKLEKIVDNKHMRDKFTPAYLATPTYTMIGYKMVSNVDNFDQALWQYGENTKVKTIGGIYN 8k23 C 3.75 BS02 dna Q 0 N85 P87 I88 N85 P87 I88 F1D5V7 18 ~ 60 MRKFIIVKNVKVDGINAKSSDITVGMPPATTFCGLGETMSIKTGIVVKAVSYGSVKFEVRGSRFNTSVTKFAWQDRGNGGKANNNSPIQPKPLADGVFTLCFEVEWEDCAEVLVDKVTNFINTARIAGGTIASFNKPFVKVAKDAEELASVKNAMMPCYVVVDCGVEVNIFEDAVNRKLQPMVNGYKKLEKIVDNKHMRDKFTPAYLATPTYTMIGYKMVSNVDNFDQALWQYGENTKVKTIGGIYN 8k23 c 3.75 BS03 dna r 0 R63 F64 N153 M156 Y159 K218 M219 N222 R63 F64 N153 M156 Y159 K218 M219 N222 F1D5V7 15 ~ 45 MRKFIIVKNVKVDGINAKSSDITVGMPPATTFCGLGETMSIKTGIVVKAVSYGSVKFEVRGSRFNTSVTKFAWQDRGNGGKANNNSPIQPKPLADGVFTLCFEVEWEDCAEVLVDKVTNFINTARIAGGTIASFNKPFVKVAKDAEELASVKNAMMPCYVVVDCGVEVNIFEDAVNRKLQPMVNGYKKLEKIVDNKHMRDKFTPAYLATPTYTMIGYKMVSNVDNFDQALWQYGENTKVKTIGGIYN 8k23 C 3.75 BS03 dna R 0 R63 F64 N153 M156 Y159 K218 M219 N222 R63 F64 N153 M156 Y159 K218 M219 N222 F1D5V7 15 ~ 45 MRKFIIVKNVKVDGINAKSSDITVGMPPATTFCGLGETMSIKTGIVVKAVSYGSVKFEVRGSRFNTSVTKFAWQDRGNGGKANNNSPIQPKPLADGVFTLCFEVEWEDCAEVLVDKVTNFINTARIAGGTIASFNKPFVKVAKDAEELASVKNAMMPCYVVVDCGVEVNIFEDAVNRKLQPMVNGYKKLEKIVDNKHMRDKFTPAYLATPTYTMIGYKMVSNVDNFDQALWQYGENTKVKTIGGIYN 8k23 d 3.75 BS01 dna U 0 L22 V23 K24 N25 L22 V23 K24 N25 0003677,0004519,0046872,0051607 F1D5W0 1 ~ 21 MQKQILTSQKRNMYILSRCKVLVKNGQVCHLHEDGNVYTVPYANTVFIGLAEGTSITNEAMSMLAANGVIVFWTKGGGYDMFAADIICHLPQADYRPTKYMQNWVRLWLDEEKKLSAAKEILKMRVDSLSTHVHDFGVDVENKRVSSIVNKFDKGVTQATSFESLLGHEGTFVKSLYKEYALEYEIEFKRDHKSADNYNKFLTLGNYYAYGIARSSLWALGIDNSFPLLHGSTRRGGLVFDVADIIKTSIILPLAFHAADQGMSNTEFKRSCVAYFDKNDILAYLINNIKRLCME 8k23 D 3.75 BS01 dna V 0 K20 L22 V23 K24 N25 G26 T57 K20 L22 V23 K24 N25 G26 T57 0003677,0004519,0046872,0051607 F1D5W0 1 ~ 21 MQKQILTSQKRNMYILSRCKVLVKNGQVCHLHEDGNVYTVPYANTVFIGLAEGTSITNEAMSMLAANGVIVFWTKGGGYDMFAADIICHLPQADYRPTKYMQNWVRLWLDEEKKLSAAKEILKMRVDSLSTHVHDFGVDVENKRVSSIVNKFDKGVTQATSFESLLGHEGTFVKSLYKEYALEYEIEFKRDHKSADNYNKFLTLGNYYAYGIARSSLWALGIDNSFPLLHGSTRRGGLVFDVADIIKTSIILPLAFHAADQGMSNTEFKRSCVAYFDKNDILAYLINNIKRLCME 8k23 E 3.75 BS01 dna U 0 R18 E52 K75 R18 E52 K75 0003677,0004519,0046872,0051607 F1D5W0 1 ~ 21 MQKQILTSQKRNMYILSRCKVLVKNGQVCHLHEDGNVYTVPYANTVFIGLAEGTSITNEAMSMLAANGVIVFWTKGGGYDMFAADIICHLPQADYRPTKYMQNWVRLWLDEEKKLSAAKEILKMRVDSLSTHVHDFGVDVENKRVSSIVNKFDKGVTQATSFESLLGHEGTFVKSLYKEYALEYEIEFKRDHKSADNYNKFLTLGNYYAYGIARSSLWALGIDNSFPLLHGSTRRGGLVFDVADIIKTSIILPLAFHAADQGMSNTEFKRSCVAYFDKNDILAYLINNIKRLCME 8k23 e 3.75 BS01 dna U 0 R18 K20 R18 K20 0003677,0004519,0046872,0051607 F1D5W0 1 ~ 21 MQKQILTSQKRNMYILSRCKVLVKNGQVCHLHEDGNVYTVPYANTVFIGLAEGTSITNEAMSMLAANGVIVFWTKGGGYDMFAADIICHLPQADYRPTKYMQNWVRLWLDEEKKLSAAKEILKMRVDSLSTHVHDFGVDVENKRVSSIVNKFDKGVTQATSFESLLGHEGTFVKSLYKEYALEYEIEFKRDHKSADNYNKFLTLGNYYAYGIARSSLWALGIDNSFPLLHGSTRRGGLVFDVADIIKTSIILPLAFHAADQGMSNTEFKRSCVAYFDKNDILAYLINNIKRLCME 8k23 E 3.75 BS02 dna V 0 R18 C19 K20 L31 H32 G53 S55 R18 C19 K20 L31 H32 G53 S55 0003677,0004519,0046872,0051607 F1D5W0 1 ~ 21 MQKQILTSQKRNMYILSRCKVLVKNGQVCHLHEDGNVYTVPYANTVFIGLAEGTSITNEAMSMLAANGVIVFWTKGGGYDMFAADIICHLPQADYRPTKYMQNWVRLWLDEEKKLSAAKEILKMRVDSLSTHVHDFGVDVENKRVSSIVNKFDKGVTQATSFESLLGHEGTFVKSLYKEYALEYEIEFKRDHKSADNYNKFLTLGNYYAYGIARSSLWALGIDNSFPLLHGSTRRGGLVFDVADIIKTSIILPLAFHAADQGMSNTEFKRSCVAYFDKNDILAYLINNIKRLCME 8k23 g 3.75 BS01 rna p 0 R14 V44 A45 G46 Q63 E93 L94 W130 R131 S202 Q203 E204 F205 Q227 K228 N231 R234 R257 R297 G298 G299 V300 R13 V43 A44 G45 Q62 E92 L93 W129 R130 S201 Q202 E203 F204 Q226 K227 N230 R233 R256 R296 G297 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 G 3.75 BS01 rna P 0 R14 V44 A45 G46 Q63 E93 L94 W130 R131 S202 Q203 E204 F205 Q227 K228 N231 R234 R257 R297 G298 G299 V300 R13 V43 A44 G45 Q62 E92 L93 W129 R130 S201 Q202 E203 F204 Q226 K227 N230 R233 R256 R296 G297 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 g 3.75 BS02 dna q 0 A8 K59 G60 N61 I62 Q63 S212 V300 A7 K58 G59 N60 I61 Q62 S211 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 G 3.75 BS02 dna Q 0 A8 K59 G60 N61 I62 Q63 S212 V300 A7 K58 G59 N60 I61 Q62 S211 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 h 3.75 BS01 rna p 0 D13 N17 R91 K92 D94 T95 K96 S97 K100 L101 R103 R104 K107 R108 L119 Y120 Y123 K124 K127 C128 Y132 S137 S139 T140 Q142 R143 F144 S145 F147 N158 S159 Y160 I164 D13 N17 R91 K92 D94 T95 K96 S97 K100 L101 R103 R104 K107 R108 L119 Y120 Y123 K124 K127 C128 Y132 S137 S139 T140 Q142 R143 F144 S145 F147 N158 S159 Y160 I164 F1D5V5 -7 ~ 52 YNTISITVVDADDVGVNFVVSKVLSTLHNKGIFNGEVGVTFPRMDKNVGDIITLFSKTGVDRKVLTSTLNTLTDFIHIGKPKEADKVKTYRKVDTKSKGKLIRRCIKRKGVSAETAESLYGNYKGEKCKLPYIVVNSKSTGQRFSMFLEECENSEKFNSYGLCIV 8k23 H 3.75 BS01 rna P 0 D13 N17 R91 K92 D94 T95 K96 S97 K100 L101 R103 R104 K107 R108 L119 Y120 Y123 K124 K127 C128 Y132 S137 S139 T140 Q142 R143 F144 S145 F147 N158 S159 Y160 I164 D13 N17 R91 K92 D94 T95 K96 S97 K100 L101 R103 R104 K107 R108 L119 Y120 Y123 K124 K127 C128 Y132 S137 S139 T140 Q142 R143 F144 S145 F147 N158 S159 Y160 I164 F1D5V5 -7 ~ 52 YNTISITVVDADDVGVNFVVSKVLSTLHNKGIFNGEVGVTFPRMDKNVGDIITLFSKTGVDRKVLTSTLNTLTDFIHIGKPKEADKVKTYRKVDTKSKGKLIRRCIKRKGVSAETAESLYGNYKGEKCKLPYIVVNSKSTGQRFSMFLEECENSEKFNSYGLCIV 8k23 i 3.75 BS01 rna p 0 A11 Y12 S13 R14 V44 A45 G46 L94 W130 R131 S202 Q203 F205 V206 H225 Q227 K228 N231 R234 R257 R297 G298 G299 V300 A10 Y11 S12 R13 V43 A44 G45 L93 W129 R130 S201 Q202 F204 V205 H224 Q226 K227 N230 R233 R256 R296 G297 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 I 3.75 BS01 rna P 0 A11 Y12 S13 R14 V44 A45 G46 L94 W130 R131 S202 Q203 F205 V206 H225 Q227 K228 N231 R234 R257 R297 G298 G299 V300 A10 Y11 S12 R13 V43 A44 G45 L93 W129 R130 S201 Q202 F204 V205 H224 Q226 K227 N230 R233 R256 R296 G297 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 i 3.75 BS02 dna q 0 A8 Q48 V50 K59 G60 N61 I62 Q63 L94 F205 A7 Q47 V49 K58 G59 N60 I61 Q62 L93 F204 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 I 3.75 BS02 dna Q 0 A8 Q48 V50 K59 G60 N61 I62 Q63 L94 F205 A7 Q47 V49 K58 G59 N60 I61 Q62 L93 F204 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 j 3.75 BS01 rna p 0 R14 V44 A45 G46 E93 L94 W130 R131 Q203 F205 Q227 K228 N231 R234 R257 R297 G299 V300 R13 V43 A44 G45 E92 L93 W129 R130 Q202 F204 Q226 K227 N230 R233 R256 R296 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 J 3.75 BS01 rna P 0 R14 V44 A45 G46 E93 L94 W130 R131 Q203 F205 Q227 K228 N231 R234 R257 R297 G299 V300 R13 V43 A44 G45 E92 L93 W129 R130 Q202 F204 Q226 K227 N230 R233 R256 R296 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 j 3.75 BS02 dna q 0 A8 V9 V50 K59 G60 N61 I62 Q63 F205 E207 V300 A7 V8 V49 K58 G59 N60 I61 Q62 F204 E206 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 J 3.75 BS02 dna Q 0 A8 V9 V50 K59 G60 N61 I62 Q63 F205 E207 V300 A7 V8 V49 K58 G59 N60 I61 Q62 F204 E206 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 k 3.75 BS01 rna p 0 Y12 S13 R14 V44 A45 G46 E93 L94 W130 R131 Q203 E204 F205 H225 Q227 K228 N231 R234 R257 G298 G299 V300 Y11 S12 R13 V43 A44 G45 E92 L93 W129 R130 Q202 E203 F204 H224 Q226 K227 N230 R233 R256 G297 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 K 3.75 BS01 rna P 0 Y12 S13 R14 V44 A45 G46 E93 L94 W130 R131 Q203 E204 F205 H225 Q227 K228 N231 R234 R257 G298 G299 V300 Y11 S12 R13 V43 A44 G45 E92 L93 W129 R130 Q202 E203 F204 H224 Q226 K227 N230 R233 R256 G297 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 k 3.75 BS02 dna q 0 Q48 G60 N61 I62 Q63 F205 Q47 G59 N60 I61 Q62 F204 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 K 3.75 BS02 dna Q 0 Q48 G60 N61 I62 Q63 F205 Q47 G59 N60 I61 Q62 F204 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 k 3.75 BS03 dna r 0 S209 K210 S208 K209 F1D5V6 15 ~ 45 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 K 3.75 BS03 dna R 0 S209 K210 S208 K209 F1D5V6 15 ~ 45 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 l 3.75 BS01 rna p 0 A11 Y12 R14 E93 L94 W130 Q203 E204 F205 V206 K213 H225 Q227 K228 N231 R234 R257 R297 G299 V300 A10 Y11 R13 E92 L93 W129 Q202 E203 F204 V205 K212 H224 Q226 K227 N230 R233 R256 R296 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 L 3.75 BS01 rna P 0 A11 Y12 R14 E93 L94 W130 Q203 E204 F205 V206 K213 H225 Q227 K228 N231 R234 R257 R297 G299 V300 A10 Y11 R13 E92 L93 W129 Q202 E203 F204 V205 K212 H224 Q226 K227 N230 R233 R256 R296 G298 V299 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 l 3.75 BS02 dna q 0 A8 V9 F205 E207 N208 V300 A7 V8 F204 E206 N207 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 L 3.75 BS02 dna Q 0 A8 V9 F205 E207 N208 V300 A7 V8 F204 E206 N207 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 m 3.75 BS01 rna p 0 A11 Y12 R14 V44 A45 Q63 E93 L94 W130 R131 S202 Q203 E204 F205 H225 Q227 K228 N231 R234 R257 G298 G299 A10 Y11 R13 V43 A44 Q62 E92 L93 W129 R130 S201 Q202 E203 F204 H224 Q226 K227 N230 R233 R256 G297 G298 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 M 3.75 BS01 rna P 0 A11 Y12 R14 V44 A45 Q63 E93 L94 W130 R131 S202 Q203 E204 F205 H225 Q227 K228 N231 R234 R257 G298 G299 A10 Y11 R13 V43 A44 Q62 E92 L93 W129 R130 S201 Q202 E203 F204 H224 Q226 K227 N230 R233 R256 G297 G298 F1D5V6 -7 ~ 52 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 m 3.75 BS02 dna q 0 A8 V9 Q48 V50 N61 I62 Q63 F205 E207 S212 V300 A7 V8 Q47 V49 N60 I61 Q62 F204 E206 S211 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG 8k23 M 3.75 BS02 dna Q 0 A8 V9 Q48 V50 N61 I62 Q63 F205 E207 S212 V300 A7 V8 Q47 V49 N60 I61 Q62 F204 E206 S211 V299 F1D5V6 18 ~ 60 TKLKAPAVLAYSRKINPTNALMFAVNWSDRDNTTAVMVGTKTVAGTQSVRGNPNDADKGNIQTVNFANLPHNKNTLLVKYNVKFVGDVFKAELGGGEYSNTLQTALENTDFGTLAYRYVYNIAAGRTLWRNRVGAESIETVITVNDQTFTFSDLLVNEFDEDVDVAEIADMVAGVLSGEGFVTLKVEHYMLLGEGSEVFPSQEFVENSKLSKQLFDLNGQAAMHDQKIGNAIRTIDTWYEDATTPIAVEPYGSVVRNGVAYRAGNKTDLFTLMDGAVNGKSLTEEDQMFVTANLIRGGVFGG