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BioLiP
Download all results in tab-seperated text for 39065 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    Peptide
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    37801 8tj5:T
    (6.6)
    BS01 >8tj5:8 (identical to 8agu:1, 8agw:1, 7aoi:UH, 6ccv:G, 8ddq:E, 8ddq:F, 8ddq:G, 8ddq:H, 8ddr:E, 8ddr:F, 8ddr:G, 8ddr:H, 8dds:E, 8dds:F, 8dds:G, 8dds:H, 8ddt:E, 8ddt:F, 8ddt:G, 8ddt:H, 8ddu:E, 8ddu:F, 8ddu:G, 8ddu:H, 8ddv:E, 8ddv:F, 8ddv:G, 8ddv:H, 8ddw:E, 8ddw:F, 8ddw:G, 8ddw:H, 8ddx:E, 8ddx:F, 8ddx:G, 8ddx:H, 8ed7:E, 8ed7:F, 8ed7:G, 8ed7:H, 8ed8:E, 8ed8:F, 8ed8:G, 8ed8:H, 8ed9:E, 8ed9:F, 8ed9:G, 8ed9:H, 8eio:B, 8gls:B, 8gym:qM, 8gym:qm, 8gym:Qm, 8gym:u2, 8gym:U2, 8gym:QM, 8gzu:0J, 8gzu:54, 8gzu:qM, 8gzu:qm, 8gzu:QM, 8gzu:Qm, 8gzu:u2, 8gzu:U2, 6h8k:Z, 3hdi:D, 6iaw:X, 3jd5:z, 6msm:B, 6o1v:B, 6o2p:B, 6q3g:PD, 6q3g:PJ, 6q3g:PK, 6q3g:PP, 6q3g:PS, 7sv7:B, 7svd:B, 8tj5:7, 8tj5:c, 8tj5:h, 5tw1:G, 6vvs:G, 7xbk:L)
    AAAAAAAAAAAAAAAAA
    ? GO:0000055 ... P34077 37738963
    37802 8tj5:Y
    (6.6)
    BS01 >8tj5:n (identical to 7aoi:UJ, 5fn4:G, 6h8k:l, 1izl:X, 4pi0:N, 4pi2:N, 8tj5:m, 4wz7:AG, 6x89:B, 5yq7:Y, 6yxx:UK)
    AAAAAAAAAAAAAAAAAAAAAAAAA
    ? GO:0000972 ... P38181 37738963
    37803 8tk7:A
    (2.53)
    BS01 >8tk7:D (identical to 9b9q:H, 8tk7:E, 8tk7:F)
    EKRLTVGSLR
    ? GO:0006826 ... Q1D6H4 37657675
    37804 8tk7:B
    (2.53)
    BS01 >8tk7:E (identical to 9b9q:H, 8tk7:D, 8tk7:F)
    EKRLTVGSLR
    ? GO:0006826 ... Q1D6H4 37657675
    37805 8tk7:C
    (2.53)
    BS01 >8tk7:F (identical to 9b9q:H, 8tk7:E, 8tk7:D)
    EKRLTVGSLR
    ? GO:0006826 ... Q1D6H4 37657675
    37806 8tl6:A
    (2.63)
    BS01 >8tl6:E
    SEQIIVTEKTNILLRYLHQQWDKKNA
    ? GO:0003676 ... Q16531 38538798
    37807 8tl6:B
    (2.63)
    BS01 >8tl6:E
    SEQIIVTEKTNILLRYLHQQWDKKNA
    ? GO:0005515 ... Q96JK2 38538798
    37808 8tlv:A
    (2.659)
    BS01 >8tlv:B (identical to 8tlw:B)
    cPVAAP
    ? GO:0005515 ... P0AEX9
    P42568
    38747396
    37809 8tlw:A
    (2.106)
    BS01 >8tlw:B (identical to 8tlv:B)
    cPVAAP
    ? GO:0005515 ... P0AEX9
    P42568
    38747396
    37810 8tlx:A
    (2.097)
    BS01 >8tlx:B
    LPVAAPL
    ? GO:0005515 ... P0AEX9
    P42568
    38747396
    37811 8tmy:A
    (3.07)
    BS01 >8tmy:M (identical to 8tmy:S)
    SFKEELDKYFKN
    N/A N/A N/A N/A
    37812 8tmy:B
    (3.07)
    BS01 >8tmy:M (identical to 8tmy:S)
    SFKEELDKYFKN
    N/A N/A N/A N/A
    37813 8tmy:C
    (3.07)
    BS01 >8tmy:N
    LDSFKEELDKYFKNHT
    N/A N/A N/A N/A
    37814 8tmy:D
    (3.07)
    BS01 >8tmy:N
    LDSFKEELDKYFKNHT
    N/A N/A N/A N/A
    37815 8tmy:H
    (3.07)
    BS01 >8tmy:S (identical to 8tmy:M)
    SFKEELDKYFKN
    N/A N/A N/A N/A
    37816 8tmy:L
    (3.07)
    BS01 >8tmy:S (identical to 8tmy:M)
    SFKEELDKYFKN
    N/A N/A N/A N/A
    37817 8tmz:H
    (1.8)
    BS01 >8tmz:A (identical to 8dgx:C, 8dgx:D)
    GIDFQDELDEFFKNV
    N/A N/A N/A N/A
    37818 8tmz:L
    (1.8)
    BS01 >8tmz:A (identical to 8dgx:C, 8dgx:D)
    GIDFQDELDEFFKNV
    N/A N/A N/A N/A
    37819 8tof:B
    (2.8)
    BS01 >8tof:x
    AAAKAAA
    3.5.1.98 GO:0000082 ... P32561 38065958
    37820 8tof:c
    (2.8)
    BS01 >8tof:H
    AARAA
    ? GO:0000786 ... P06897 38065958
    37821 8tof:d
    (2.8)
    BS01 >8tof:H
    AARAA
    ? GO:0000786 ... P02281 38065958
    37822 8toq:A
    (2.3)
    BS01 >8toq:E
    YVFRSLRTPFIV
    3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 38085789
    37823 8tor:A
    (2.2)
    BS01 >8tor:E (identical to 8tot:C, 8tot:D, 8tou:B)
    YFQRSVRLPYLRC
    3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 38085789
    37824 8tos:A
    (2.35)
    BS01 >8tos:E
    ARPLRHRPWYVS
    3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 38085789
    37825 8tot:A
    (2.8)
    BS01 >8tot:C (identical to 8tor:E, 8tot:D, 8tou:B)
    YFQRSVRLPYLRC
    3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 38085789
    37826 8tot:B
    (2.8)
    BS01 >8tot:D (identical to 8tor:E, 8tot:C, 8tou:B)
    YFQRSVRLPYLRC
    3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 38085789
    37827 8tou:A
    (3.1)
    BS01 >8tou:B (identical to 8tor:E, 8tot:C, 8tot:D)
    YFQRSVRLPYLRC
    3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 38085789
    37828 8tpj:J
    (2.1)
    BS01 >8tpj:S
    NEVRRFIPQE
    ? GO:0009579 ... Q01951 38578996
    37829 8tpj:K
    (2.1)
    BS01 >8tpj:S
    NEVRRFIPQE
    ? GO:0009579 ... Q01952 38578996
    37830 8tpj:N
    (2.1)
    BS01 >8tpj:R
    RRFI
    ? GO:0009579 ... Q01951 38578996
    37831 8tq7:A
    (2.8)
    BS01 >8tq7:P (identical to 1bii:P, 1ddh:P, 3dmm:P, 3ecb:P, 5ivx:P, 6npr:P, 6npr:R, 1qo3:P, 8tq7:E, 8tq8:P, 8tq8:E, 8tq9:P)
    RGPGRAFVTI
    ? N/A P01900 38456672
    37832 8tq7:C
    (2.8)
    BS01 >8tq7:E (identical to 1bii:P, 1ddh:P, 3dmm:P, 3ecb:P, 5ivx:P, 6npr:P, 6npr:R, 1qo3:P, 8tq7:P, 8tq8:P, 8tq8:E, 8tq9:P)
    RGPGRAFVTI
    ? N/A P01900 38456672
    37833 8tq8:A
    (2.69)
    BS01 >8tq8:P (identical to 1bii:P, 1ddh:P, 3dmm:P, 3ecb:P, 5ivx:P, 6npr:P, 6npr:R, 1qo3:P, 8tq7:E, 8tq7:P, 8tq8:E, 8tq9:P)
    RGPGRAFVTI
    ? N/A P01900 38456672
    37834 8tq8:C
    (2.69)
    BS01 >8tq8:E (identical to 1bii:P, 1ddh:P, 3dmm:P, 3ecb:P, 5ivx:P, 6npr:P, 6npr:R, 1qo3:P, 8tq7:E, 8tq7:P, 8tq8:P, 8tq9:P)
    RGPGRAFVTI
    ? N/A P01900 38456672
    37835 8tq9:A
    (2.9)
    BS01 >8tq9:P (identical to 1bii:P, 1ddh:P, 3dmm:P, 3ecb:P, 5ivx:P, 6npr:P, 6npr:R, 1qo3:P, 8tq7:E, 8tq7:P, 8tq8:P, 8tq8:E)
    RGPGRAFVTI
    ? N/A P01900 38456672
    37836 8tqa:A
    (2.6)
    BS01 >8tqa:P (identical to 1hoc:C, 4hux:C, 7jwi:C, 7jwj:C, 5sws:C, 5swz:C, 5swz:H, 5swz:M, 5swz:R)
    ASNENMETM
    ? N/A P01899 38456672
    37837 8tqu:A
    (1.85)
    BS01 >8tqu:B (identical to 6xbh:C)
    FL
    N/A N/A P0DTD1 N/A
    37838 8trl:A
    (2.4)
    BS01 >8trl:C (identical to 8trl:F)
    EIFDSRGNPTGEV
    N/A N/A P01903 39043656
    37839 8trl:B
    (2.4)
    BS01 >8trl:C (identical to 8trl:F)
    EIFDSRGNPTGEV
    N/A N/A P01911 39043656
    37840 8trl:D
    (2.4)
    BS01 >8trl:F (identical to 8trl:C)
    EIFDSRGNPTGEV
    N/A N/A P01903 39043656
    37841 8trl:E
    (2.4)
    BS01 >8trl:F (identical to 8trl:C)
    EIFDSRGNPTGEV
    N/A N/A P01911 39043656
    37842 8trl:G
    (2.4)
    BS01 >8trl:F (identical to 8trl:C)
    EIFDSRGNPTGEV
    N/A N/A N/A 39043656
    37843 8trl:H
    (2.4)
    BS01 >8trl:F (identical to 8trl:C)
    EIFDSRGNPTGEV
    N/A N/A N/A 39043656
    37844 8trl:I
    (2.4)
    BS01 >8trl:C (identical to 8trl:F)
    EIFDSRGNPTGEV
    N/A N/A N/A 39043656
    37845 8trl:J
    (2.4)
    BS01 >8trl:C (identical to 8trl:F)
    EIFDSRGNPTGEV
    N/A N/A N/A 39043656
    37846 8trq:A
    (2.75)
    BS01 >8trq:C (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trr:H)
    GVYATRSSAVRLR
    N/A N/A P01903 39043656
    37847 8trq:B
    (2.75)
    BS01 >8trq:C (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trr:H)
    GVYATRSSAVRLR
    N/A N/A P01911 39043656
    37848 8trq:D
    (2.75)
    BS01 >8trq:C (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trr:H)
    GVYATRSSAVRLR
    N/A N/A N/A 39043656
    37849 8trq:E
    (2.75)
    BS01 >8trq:C (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trr:H)
    GVYATRSSAVRLR
    N/A N/A N/A 39043656
    37850 8trr:A
    (2.65)
    BS01 >8trr:C
    GVYATRSSAVRL
    N/A N/A P01903 39043656
    37851 8trr:B
    (2.65)
    BS01 >8trr:C
    GVYATRSSAVRL
    N/A N/A P01911 39043656
    37852 8trr:D
    (2.65)
    BS01 >8trr:C
    GVYATRSSAVRL
    N/A N/A N/A 39043656
    37853 8trr:E
    (2.65)
    BS01 >8trr:C
    GVYATRSSAVRL
    N/A N/A N/A 39043656
    37854 8trr:F
    (2.65)
    BS01 >8trr:H (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trq:C)
    GVYATRSSAVRLR
    N/A N/A P01903 39043656
    37855 8trr:G
    (2.65)
    BS01 >8trr:H (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trq:C)
    GVYATRSSAVRLR
    N/A N/A P01911 39043656
    37856 8trr:I
    (2.65)
    BS01 >8trr:H (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trq:C)
    GVYATRSSAVRLR
    N/A N/A N/A 39043656
    37857 8trr:J
    (2.65)
    BS01 >8trr:H (identical to 6atf:C, 6atf:F, 4mcz:C, 4md0:C, 8trq:C)
    GVYATRSSAVRLR
    N/A N/A N/A 39043656
    37858 8tta:A
    (3.46)
    BS01 >8tta:E
    FDDPLNA
    N/A N/A Q9QZ88 39116126
    37859 8tta:C
    (3.46)
    BS01 >8tta:F (identical to 8rks:K, 8rks:I, 8rks:J)
    DDPLNA
    N/A N/A Q9QZ88 39116126
    37860 8ttc:D
    (3.01)
    BS01 >8ttc:E (identical to 8ttv:B)
    DDIF
    N/A N/A Q9EQH3 39116126
    37861 8ttd:A
    (2.011)
    BS01 >8ttd:B
    DDPL
    N/A N/A Q9QZ88 39116126
    37862 8tte:A
    (3.26)
    BS01 >8tte:C (identical to 8ttg:C)
    SVENHWYYFYWYMSP
    ? GO:0005886 ... P0A0J7 38802368
    37863 8ttg:A
    (3.35)
    BS01 >8ttg:C (identical to 8tte:C)
    SVENHWYYFYWYMSP
    ? GO:0005886 ... P0A0J7 38802368
    37864 8ttl:A
    (2.6)
    BS01 >8ttl:E (identical to 8ttl:F)
    GSVQIVYKPVDLSKVTSKCGSLGNIHH
    N/A N/A P10636 38408247
    37865 8ttl:B
    (2.6)
    BS01 >8ttl:E (identical to 8ttl:F)
    GSVQIVYKPVDLSKVTSKCGSLGNIHH
    N/A N/A P10636 38408247
    37866 8ttl:C
    (2.6)
    BS01 >8ttl:F (identical to 8ttl:E)
    GSVQIVYKPVDLSKVTSKCGSLGNIHH
    N/A N/A P10636 38408247
    37867 8ttt:A
    (2.35)
    BS01 >8ttt:B
    GDIFST
    N/A N/A Q96L92 39116126
    37868 8ttu:A
    (2.36)
    BS01 >8ttu:B
    NIDIFAD
    N/A N/A Q96L92 39116126
    37869 8ttv:A
    (2.0)
    BS01 >8ttv:B (identical to 8ttc:E)
    DDIF
    N/A N/A Q96L92 39116126
    37870 8tub:C
    (2.4)
    BS01 >8tub:D (identical to 8tub:Q, 8tub:H, 8tub:K)
    HPNGYKSLSTL
    ? N/A P01889 38684663
    37871 8tub:F
    (2.4)
    BS01 >8tub:Q (identical to 8tub:D, 8tub:H, 8tub:K)
    HPNGYKSLSTL
    ? N/A P01889 38684663
    37872 8tub:F
    (2.4)
    BS02 >8tub:K (identical to 8tub:Q, 8tub:D, 8tub:H)
    HPNGYKSLSTL
    ? N/A P01889 38684663
    37873 8tub:G
    (2.4)
    BS01 >8tub:H (identical to 8tub:Q, 8tub:D, 8tub:K)
    HPNGYKSLSTL
    ? N/A P01889 38684663
    37874 8tub:J
    (2.4)
    BS01 >8tub:Q (identical to 8tub:D, 8tub:H, 8tub:K)
    HPNGYKSLSTL
    ? N/A P01889 38684663
    37875 8tub:J
    (2.4)
    BS02 >8tub:K (identical to 8tub:Q, 8tub:D, 8tub:H)
    HPNGYKSLSTL
    ? N/A P01889 38684663
    37876 8tuh:A
    (2.20011)
    BS01 >8tuh:F
    RPIIRPATL
    ? N/A P01889 38684663
    37877 8tuq:A
    (2.0)
    BS01 >8tuq:B
    KRKFPDSSTQNSTPPKKNKPA
    ? GO:0005737 ... P52293 38108201
    37878 8tur:A
    (2.15)
    BS01 >8tur:B
    RKRKFGTSTPPKPKKNRE
    ? GO:0005737 ... P52293 38108201
    37879 8tus:A
    (2.6)
    BS01 >8tus:C
    KRTATPPKKKKD
    ? GO:0005737 ... P52293 38108201
    37880 8tut:A
    (2.55)
    BS01 >8tut:B
    PPKPKKNRE
    ? GO:0005737 ... P52293 38108201
    37881 8tuu:A
    (2.5)
    BS01 >8tuu:B
    PKKRPRPPKRPRN
    ? GO:0005737 ... P52293 38108201
    37882 8tuv:A
    (2.3)
    BS01 >8tuv:B
    SRKRKF
    ? GO:0005737 ... P52293 38108201
    37883 8tuv:A
    (2.3)
    BS02 >8tuv:C
    ARKRVRK
    ? GO:0005737 ... P52293 38108201
    37884 8tw0:A
    (1.53)
    BS01 >8tw0:B
    SKGDPGPPGDRGPKGPPGYKGPPGDKGFR
    N/A N/A N/A 39009792
    37885 8tw0:C
    (1.53)
    BS01 >8tw0:B
    SKGDPGPPGDRGPKGPPGYKGPPGDKGFR
    N/A N/A N/A 39009792
    37886 8tw9:B
    (3.6)
    BS01 >8tw9:C (identical to 5oki:E, 5oki:I, 6s2e:E, 6s2f:E, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    N/A N/A P25559 N/A
    37887 8tw9:D
    (3.6)
    BS01 >8tw9:C (identical to 5oki:E, 5oki:I, 6s2e:E, 6s2f:E, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    N/A N/A P38877 N/A
    37888 8tw9:E
    (3.6)
    BS01 >8tw9:C (identical to 5oki:E, 5oki:I, 6s2e:E, 6s2f:E, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    N/A N/A P21951 N/A
    37889 8twa:B
    (4.1)
    BS01 >8twa:C (identical to 5oki:E, 5oki:I, 6s2e:E, 6s2f:E, 8tw9:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    N/A N/A P25559 N/A
    37890 8twa:D
    (4.1)
    BS01 >8twa:C (identical to 5oki:E, 5oki:I, 6s2e:E, 6s2f:E, 8tw9:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    N/A N/A P38877 N/A
    37891 8twa:E
    (4.1)
    BS01 >8twa:C (identical to 5oki:E, 5oki:I, 6s2e:E, 6s2f:E, 8tw9:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    N/A N/A P21951 N/A
    37892 8twe:A
    (2.55)
    BS01 >8twe:C
    HVTRRTPDYFL
    ? GO:0000159 ... P30153 38123684
    37893 8twe:B
    (2.55)
    BS01 >8twe:C
    HVTRRTPDYFL
    ? GO:0000159 ... P63151 38123684
    37894 8twe:B
    (2.55)
    BS02 >8twe:D
    HSSRLHQIKQEE
    ? GO:0000159 ... P63151 38123684
    37895 8twi:C
    (2.69)
    BS01 >8twi:D
    GMDLINRETVHEREVQTAM
    3.1.3.16 GO:0000159 ... P67775 38123684
    37896 8two:A
    (2.09)
    BS01 >8two:B (identical to 8tws:B, 8txf:B)
    APKFGDWDENNPSSADGYTHIFNKV
    ? GO:0005576 ... P13835 38354245
    37897 8tws:A
    (2.85)
    BS01 >8tws:B (identical to 8two:B, 8txf:B)
    APKFGDWDENNPSSADGYTHIFNKV
    ? GO:0005576 ... P13835 38354245
    37898 8txf:A
    (1.29)
    BS01 >8txf:B (identical to 8two:B, 8tws:B)
    APKFGDWDENNPSSADGYTHIFNKV
    ? GO:0005576 ... P13835 38354245
    37899 8txv:G
    (3.8)
    BS03 >8txv:K (identical to 8txw:K)
    NRQKGSPDEYHLRA
    ? GO:0000786 ... P04908 38242129
    37900 8txv:H
    (3.8)
    BS03 >8txv:K (identical to 8txw:K)
    NRQKGSPDEYHLRA
    ? GO:0000786 ... P62807 38242129

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218