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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 39065 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    Peptide
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    18901 5nx3:D
    (2.296)
    BS01 >5nx3:B (identical to 5nx1:B)
    EVCSEQAETGPCR
    ? GO:0004867 ... P05067 29934309
    18902 5nxq:A
    (2.413)
    BS01 >5nxq:D (identical to 5nxq:E)
    MDIAIDDILAELDKE
    ? N/A Q01454 28815832
    18903 5nxq:B
    (2.413)
    BS01 >5nxq:E (identical to 5nxq:D)
    MDIAIDDILAELDKE
    ? N/A Q01454 28815832
    18904 5o0e:A
    (1.5)
    BS01 >5o0e:C (identical to 6eh3:C, 6em7:D, 6ema:C, 6eru:B, 6esa:E, 5o5m:C)
    TTYADFIASGRTGRRSAI
    2.7.11.11 GO:0000287 ... P25321 N/A
    18905 5o3u:A
    (1.86)
    BS01 >5o3u:L
    FSASYSSKPIQTNASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18906 5o3u:B
    (1.86)
    BS01 >5o3u:M (identical to 5o3u:O)
    FSASYSSKPIQDNASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18907 5o3u:C
    (1.86)
    BS01 >5o3u:N
    FSASYSSKPIQNASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18908 5o3u:D
    (1.86)
    BS01 >5o3u:O (identical to 5o3u:M)
    FSASYSSKPIQDNASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18909 5o3v:A
    (2.17)
    BS01 >5o3v:C
    VAWAFQANASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18910 5o3v:B
    (2.17)
    BS01 >5o3v:D
    GVAWAFQANASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18911 5o3w:A
    (2.0)
    BS01 >5o3w:W
    ENASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18912 5o3w:B
    (2.0)
    BS01 >5o3w:X (identical to 5o3w:Y, 5uw3:E, 5uw3:F, 5uw3:G, 5uw3:H, 5uw5:E, 5uw5:F, 5uw5:G, 5uw5:H, 5uw6:E, 5uw6:F, 5uw6:G, 5uw6:H, 5uw7:C, 5uw7:D, 5uzw:E, 5uzw:F, 5uzw:G, 5uzw:H)
    NASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18913 5o3w:C
    (2.0)
    BS01 >5o3w:Y (identical to 5o3w:X, 5uw3:E, 5uw3:F, 5uw3:G, 5uw3:H, 5uw5:E, 5uw5:F, 5uw5:G, 5uw5:H, 5uw6:E, 5uw6:F, 5uw6:G, 5uw6:H, 5uw7:C, 5uw7:D, 5uzw:E, 5uzw:F, 5uzw:G, 5uzw:H)
    NASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18914 5o3w:D
    (2.0)
    BS01 >5o3w:Z
    VENASAPV
    3.4.21.-
    3.4.21.26
    GO:0004252 ... R4P353 29377663
    18915 5o45:A
    (0.99)
    BS01 >5o45:B
    FFKGDVFYGWYLCG
    ? N/A Q9NZQ7 28881104
    18916 5o4y:B
    (2.3)
    BS01 >5o4y:D (identical to 5o4y:A, 5o4y:F)
    FANPHLSWSWKKRCG
    ? N/A Q9NZQ7 28881104
    18917 5o4y:C
    (2.3)
    BS01 >5o4y:F (identical to 5o4y:A, 5o4y:D)
    FANPHLSWSWKKRCG
    ? N/A Q9NZQ7 28881104
    18918 5o4y:E
    (2.3)
    BS01 >5o4y:A (identical to 5o4y:D, 5o4y:F)
    FANPHLSWSWKKRCG
    ? N/A Q9NZQ7 28881104
    18919 5o4y:E
    (2.3)
    BS02 >5o4y:D (identical to 5o4y:A, 5o4y:F)
    FANPHLSWSWKKRCG
    ? N/A Q9NZQ7 28881104
    18920 5o5b:1
    (3.6)
    BS01 >5o5b:4 (identical to 5o5p:4)
    INYTTINYYKDSASNAA
    ? GO:0005198 ... Q84895 28811473
    18921 5o5b:3
    (3.6)
    BS01 >5o5b:4 (identical to 5o5p:4)
    INYTTINYYKDSASNAA
    ? GO:0005198 ... Q84895 28811473
    18922 5o5j:S
    (3.45)
    BS02 >5o5j:g (identical to 8wi9:x, 8wid:x, 8wif:x)
    GRVARFEKRYG
    ? GO:0000028 ... A0QSD5 28683309
    18923 5o5m:A
    (1.583)
    BS01 >5o5m:C (identical to 6eh3:C, 6em7:D, 6ema:C, 6eru:B, 6esa:E, 5o0e:C)
    TTYADFIASGRTGRRSAI
    2.7.11.11 GO:0000287 ... P25321 N/A
    18924 5o5p:1
    (4.1)
    BS01 >5o5p:4 (identical to 5o5b:4)
    INYTTINYYKDSASNAA
    ? GO:0005198 ... Q84895 28811473
    18925 5o5p:3
    (4.1)
    BS01 >5o5p:4 (identical to 5o5b:4)
    INYTTINYYKDSASNAA
    ? GO:0005198 ... Q84895 28811473
    18926 5o76:A
    (2.473)
    BS01 >5o76:B
    DGYTPEP
    2.3.2.27 GO:0001784 ... P22681 29053960
    18927 5o76:C
    (2.473)
    BS01 >5o76:D (identical to 4a4b:B, 4a4c:B, 2cbl:B, 1fbv:B, 2y1n:B, 2y1n:D, 3zni:B, 3zni:N)
    SDGYTPEPA
    2.3.2.27 GO:0001784 ... P22681 29053960
    18928 5o8k:A
    (1.8)
    BS01 >5o8k:B (identical to 3abe:Z)
    ANILKPLMSPPSREEIMATLL
    ? GO:0000122 ... Q9D752 N/A
    18929 5o90:A
    (2.49)
    BS01 >5o90:B
    RVYPVSVPYSSVTLSLVMP
    2.7.11.24 GO:0000077 ... P47811 29229647
    18930 5o9s:A
    (2.7)
    BS01 >5o9s:C (identical to 5o9s:D)
    GKSNSKLK
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18931 5o9s:B
    (2.7)
    BS01 >5o9s:D (identical to 5o9s:C)
    GKSNSKLK
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18932 5o9t:A
    (2.15)
    BS01 >5o9t:C (identical to 5o9t:D)
    NCFSKPR
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18933 5o9t:B
    (2.15)
    BS01 >5o9t:D (identical to 5o9t:C)
    NCFSKPR
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18934 5o9u:A
    (1.85)
    BS01 >5o9u:C (identical to 5o9u:D)
    GCSVSKKK
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18935 5o9u:B
    (1.85)
    BS01 >5o9u:D (identical to 5o9u:C)
    GCSVSKKK
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18936 5o9v:A
    (2.201)
    BS01 >5o9v:C (identical to 5o9v:D)
    GGCFSKPK
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18937 5o9v:B
    (2.201)
    BS01 >5o9v:D (identical to 5o9v:C)
    GGCFSKPK
    2.3.1.-
    2.3.1.97
    GO:0004379 ... P30419 29892081
    18938 5o9z:L
    (4.5)
    BS01 >5o9z:R
    EFKTRLGRNVYRMLFK
    ? GO:0000381 ... Q2TAY7 28781166
    18939 5oak:A
    (1.5)
    BS01 >5oak:B (identical to 5oak:D)
    GSGVKDGVLHL
    ? N/A Q0KHR3 29440511
    18940 5oak:C
    (1.5)
    BS01 >5oak:B (identical to 5oak:D)
    GSGVKDGVLHL
    ? N/A Q0KHR3 29440511
    18941 5oak:C
    (1.5)
    BS02 >5oak:D (identical to 5oak:B)
    GSGVKDGVLHL
    ? N/A Q0KHR3 29440511
    18942 5oav:A
    (0.95)
    BS01 >5oav:B (identical to 4rtw:B)
    APPLPPR
    2.7.10.2 N/A P00523 N/A
    18943 5oav:A
    (0.95)
    BS02 >5oav:D (identical to 5ob2:B)
    APPLPPRNRPR
    2.7.10.2 N/A P00523 N/A
    18944 5oav:C
    (0.95)
    BS01 >5oav:D (identical to 5ob2:B)
    APPLPPRNRPR
    2.7.10.2 N/A P00523 N/A
    18945 5ob0:A
    (1.172)
    BS01 >5ob0:B (identical to 5ob1:B, 1qwe:B, 4rtw:D, 4rty:B)
    APPLPPRNRPRL
    2.7.10.2 N/A P00523 N/A
    18946 5ob1:A
    (1.172)
    BS01 >5ob1:B (identical to 5ob0:B, 1qwe:B, 4rtw:D, 4rty:B)
    APPLPPRNRPRL
    2.7.10.2 N/A P00523 N/A
    18947 5ob2:A
    (1.8)
    BS01 >5ob2:B (identical to 5oav:D)
    APPLPPRNRPR
    2.7.10.2 N/A P00523 N/A
    18948 5ob2:A
    (1.8)
    BS02 >5ob2:D (identical to 4hvu:B, 4hvv:B, 4rtv:B, 4znx:E, 4znx:F, 4znx:H)
    APPLPPRNRP
    2.7.10.2 N/A P00523 N/A
    18949 5ob2:C
    (1.8)
    BS01 >5ob2:B (identical to 5oav:D)
    APPLPPRNRPR
    2.7.10.2 N/A P00523 N/A
    18950 5ob2:C
    (1.8)
    BS02 >5ob2:D (identical to 4hvu:B, 4hvv:B, 4rtv:B, 4znx:E, 4znx:F, 4znx:H)
    APPLPPRNRP
    2.7.10.2 N/A P00523 N/A
    18951 5obt:A
    (1.5)
    BS01 >5obt:C (identical to 4aw9:I, 4awa:I, 3gjs:E, 3gjs:F, 3ibc:E, 3ibc:F, 1ice:T, 5lu8:C, 5lu9:C, 5obt:D)
    YVAD
    3.4.22.34 GO:0006508 ... Q39119 29628443
    18952 5obt:B
    (1.5)
    BS01 >5obt:C (identical to 4aw9:I, 4awa:I, 3gjs:E, 3gjs:F, 3ibc:E, 3ibc:F, 1ice:T, 5lu8:C, 5lu9:C, 5obt:D)
    YVAD
    3.4.22.34 GO:0006508 ... Q39119 29628443
    18953 5obt:B
    (1.5)
    BS02 >5obt:D (identical to 4aw9:I, 4awa:I, 3gjs:E, 3gjs:F, 3ibc:E, 3ibc:F, 1ice:T, 5lu8:C, 5lu9:C, 5obt:C)
    YVAD
    3.4.22.34 GO:0006508 ... Q39119 29628443
    18954 5ock:H
    (1.6)
    BS01 >5ock:A
    aCKIHAtFDStGNPTVEC
    N/A N/A N/A 30152126
    18955 5ock:L
    (1.6)
    BS01 >5ock:A
    aCKIHAtFDStGNPTVEC
    N/A N/A N/A 30152126
    18956 5ocx:H
    (1.75)
    BS01 >5ocx:A
    GEEGKtGARG
    N/A N/A N/A 30152126
    18957 5ocx:L
    (1.75)
    BS01 >5ocx:A
    GEEGKtGARG
    N/A N/A N/A 30152126
    18958 5ocy:H
    (2.6)
    BS01 >5ocy:C (identical to 6zjg:B)
    EPGEtGLKG
    N/A N/A N/A 30152126
    18959 5ocy:L
    (2.6)
    BS01 >5ocy:C (identical to 6zjg:B)
    EPGEtGLKG
    N/A N/A N/A 30152126
    18960 5ods:A
    (3.09)
    BS01 >5ods:E (identical to 5ods:F, 5ods:G, 5ods:H)
    KESALRKQSLYLKFDPLL
    ? GO:0005198 ... Q68FD5 N/A
    18961 5ods:B
    (3.09)
    BS01 >5ods:F (identical to 5ods:E, 5ods:G, 5ods:H)
    KESALRKQSLYLKFDPLL
    ? GO:0005198 ... Q68FD5 N/A
    18962 5ods:C
    (3.09)
    BS01 >5ods:G (identical to 5ods:E, 5ods:F, 5ods:H)
    KESALRKQSLYLKFDPLL
    ? GO:0005198 ... Q68FD5 N/A
    18963 5ods:D
    (3.09)
    BS01 >5ods:H (identical to 5ods:E, 5ods:F, 5ods:G)
    KESALRKQSLYLKFDPLL
    ? GO:0005198 ... Q68FD5 N/A
    18964 5ogl:A
    (2.7)
    BS01 >5ogl:B (identical to 3rce:B)
    GDQNATFG
    2.4.99.19 GO:0000287 ... B9KDD4 29058712
    18965 5oj5:A
    (1.08)
    BS01 >5oj5:B
    FPLDLA
    ? N/A Q8DI95 30061392
    18966 5ojo:A
    (3.1)
    BS01 >5ojo:C (identical to 6fky:C, 6fky:I)
    GVLKEYGV
    2.3.1.- GO:0036054 ... Q6DHI5 29138502
    18967 5ojr:A
    (1.96)
    BS01 >5ojr:E
    NAHNFPLDLASAESAPVA
    ? GO:0009523 ... Q8DI95 30061392
    18968 5ojr:B
    (1.96)
    BS01 >5ojr:F
    NAHNFPLDLASAESAPV
    ? GO:0009523 ... Q8DI95 30061392
    18969 5ok3:A
    (1.588)
    BS01 >5ok3:D
    TAYADFIASGRTGRRNAI
    2.7.11.11 GO:0000287 ... P25321 30677243
    18970 5ok6:A
    (1.3)
    BS01 >5ok6:D
    GEFYKLKIRTPR
    3.4.19.12 GO:0004843 ... P51784 30373771
    18971 5ok6:B
    (1.3)
    BS01 >5ok6:C
    AEGEFYKLKIRTPR
    3.4.19.12 GO:0004843 ... P51784 30373771
    18972 5okc:A
    (2.3)
    BS01 >5okc:I
    TVKIWVKYNEGFSNAVRKNVTWNNLWE
    ? GO:0000775 ... P25559 29225079
    18973 5okc:B
    (2.3)
    BS01 >5okc:G (identical to 5msm:F)
    VKIWVKYNEGFSNAVRKNVTWNNLWE
    ? GO:0000775 ... P25559 29225079
    18974 5okc:F
    (2.3)
    BS01 >5okc:G (identical to 5msm:F)
    VKIWVKYNEGFSNAVRKNVTWNNLWE
    ? GO:0003674 ... P38877 29225079
    18975 5okc:H
    (2.3)
    BS01 >5okc:I
    TVKIWVKYNEGFSNAVRKNVTWNNLWE
    ? GO:0003674 ... P38877 29225079
    18976 5oki:B
    (4.5)
    BS01 >5oki:I (identical to 5oki:E, 6s2e:E, 6s2f:E, 8tw9:C, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    2.7.7.7
    3.1.11.-
    GO:0003676 ... P21951 29225079
    18977 5oki:C
    (4.5)
    BS01 >5oki:E (identical to 5oki:I, 6s2e:E, 6s2f:E, 8tw9:C, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    ? GO:0000775 ... P25559 29225079
    18978 5oki:D
    (4.5)
    BS01 >5oki:E (identical to 5oki:I, 6s2e:E, 6s2f:E, 8tw9:C, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    ? GO:0003674 ... P38877 29225079
    18979 5oki:G
    (4.5)
    BS01 >5oki:I (identical to 5oki:E, 6s2e:E, 6s2f:E, 8tw9:C, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    ? GO:0000775 ... P25559 29225079
    18980 5oki:H
    (4.5)
    BS01 >5oki:I (identical to 5oki:E, 6s2e:E, 6s2f:E, 8tw9:C, 8twa:C)
    TVKIWVKYNEGFSNAVRKNVTWNNLW
    ? GO:0003674 ... P38877 29225079
    18981 5okz:G
    (3.20004)
    BS01 >5okz:J
    PNLIISNVGYVISGRKTFGD
    ? GO:0000176 ... Q08285 28877463
    18982 5okz:Q
    (3.20004)
    BS01 >5okz:T (identical to 5okz:d)
    ISGRKTF
    ? GO:0000176 ... Q08285 28877463
    18983 5okz:a
    (3.20004)
    BS01 >5okz:d (identical to 5okz:T)
    ISGRKTF
    ? GO:0000176 ... Q08285 28877463
    18984 5okz:k
    (3.20004)
    BS01 >5okz:n
    VISGRKTFGD
    ? GO:0000176 ... Q08285 28877463
    18985 5ol0:A
    (1.99)
    BS01 >5ol0:C
    RHKKLMFK
    2.3.1.286 GO:0017136 ... A0A6L0XH39 29543820
    18986 5ol0:B
    (1.99)
    BS01 >5ol0:D (identical to 1h26:E)
    SRHKKLMFK
    2.3.1.286 GO:0017136 ... A0A6L0XH39 29543820
    18987 5ol3:A
    (1.58)
    BS01 >5ol3:D (identical to 7axt:B, 7axw:B, 7baq:B, 7bb0:B, 4c33:I, 4c34:I, 4c35:I, 1ctp:I, 3e8c:G, 6e99:B, 6e9l:B, 6egw:B, 6erv:B, 6erw:D, 6f14:B, 4ij9:I, 3l9l:D, 3l9m:D, 5lcq:B, 5m0l:B, 5n1d:B, 3nx8:B, 3oog:B, 5otg:D, 5oua:B, 3oxt:B, 7pid:B, 7pie:B, 7pns:B, 3qal:I, 5uzk:I, 5vhb:B, 5vi9:B, 5vib:B, 6y05:B, 6y2o:B, 6y2u:B, 6y8c:B, 3zo1:I, 3zo2:I, 3zo3:I)
    TTYADFIASGRTGRRNAI
    2.7.11.11 GO:0000287 ... P25321 N/A
    18988 5ona:B
    (2.7)
    BS01 >5ona:C (identical to 5onb:B, 5onb:D)
    DDQQLDHNFKQMEEHLALMVEG
    ? GO:0006402 ... Q92600 29255063
    18989 5ona:E
    (2.7)
    BS01 >5ona:F
    DQQLDHNFKQMEEHLALMVEG
    ? GO:0006402 ... Q92600 29255063
    18990 5onb:A
    (3.0)
    BS01 >5onb:B (identical to 5ona:C, 5onb:D)
    DDQQLDHNFKQMEEHLALMVEG
    ? GO:0006402 ... Q92600 29255063
    18991 5onb:C
    (3.0)
    BS01 >5onb:D (identical to 5ona:C, 5onb:B)
    DDQQLDHNFKQMEEHLALMVEG
    ? GO:0006402 ... Q92600 29255063
    18992 5onb:E
    (3.0)
    BS01 >5onb:F
    DDQQLDHNFKQMEEHLALMVEGN
    ? GO:0006402 ... Q92600 29255063
    18993 5onb:G
    (3.0)
    BS01 >5onb:H
    DDQQLDHNFKQMEEHLALMVE
    ? GO:0006402 ... Q92600 29255063
    18994 5onj:A
    (1.7)
    BS01 >5onj:D
    EEEEEE
    ? N/A O31815 30387270
    18995 5onp:A
    (1.34)
    BS01 >5onp:B (identical to 5onq:B)
    GAIIG
    3.4.24.27 GO:0004222 ... P43133 30403288
    18996 5onq:A
    (1.17)
    BS01 >5onq:B (identical to 5onp:B)
    GAIIG
    3.4.24.27 GO:0004222 ... P43133 30403288
    18997 5onr:A
    (1.39)
    BS01 >5onr:B
    IIG
    3.4.24.27 GO:0004222 ... P00800 30403288
    18998 5ons:A
    (2.14)
    BS01 >5ons:B
    ADYPLRVLYCGVCSLPTEYCEYMP
    ? GO:0000339 ... Q9ULC4 29889857
    18999 5oo6:A
    (2.8)
    BS01 >5oo6:C (identical to 5oo6:F, 5oo6:O, 5oo6:R, 5oo6:X)
    DPRAIVEYRDVDFF
    ? GO:0000184 ... Q09161 29101316
    19000 5oo6:B
    (2.8)
    BS01 >5oo6:C (identical to 5oo6:F, 5oo6:O, 5oo6:R, 5oo6:X)
    DPRAIVEYRDVDFF
    ? GO:0000184 ... P52298 29101316

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218