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BioLiP
Download all results in tab-seperated text for 39065 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    Peptide
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    14601 4wfd:E
    (2.4)
    BS01 >4wfd:F (identical to 4wfd:I)
    DLFDVFEE
    ? N/A P38801 25319414
    14602 4wfd:H
    (2.4)
    BS01 >4wfd:I (identical to 4wfd:F)
    DLFDVFEE
    ? N/A P38801 25319414
    14603 4whh:A
    (1.9)
    BS01 >4whh:B (identical to 5dnj:B)
    tHST
    2.7.11.21 N/A P53350 25347203
    14604 4whk:A
    (1.8)
    BS01 >4whk:B
    cHST
    2.7.11.21 N/A P53350 25347203
    14605 4whl:A
    (2.71)
    BS01 >4whl:B (identical to 4rcp:B)
    HST
    2.7.11.21 N/A P53350 25347203
    14606 4wht:A
    (2.22)
    BS01 >4wht:a (identical to 4gag:P, 4wht:g, 4wht:i, 4wht:m, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14607 4wht:B
    (2.22)
    BS01 >4wht:a (identical to 4gag:P, 4wht:g, 4wht:i, 4wht:m, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14608 4wht:B
    (2.22)
    BS02 >4wht:i (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:m, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14609 4wht:C
    (2.22)
    BS01 >4wht:c (identical to 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14610 4wht:D
    (2.22)
    BS01 >4wht:c (identical to 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14611 4wht:D
    (2.22)
    BS02 >4wht:e (identical to 4wht:c, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14612 4wht:E
    (2.22)
    BS01 >4wht:e (identical to 4wht:c, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14613 4wht:F
    (2.22)
    BS01 >4wht:e (identical to 4wht:c, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14614 4wht:G
    (2.22)
    BS01 >4wht:g (identical to 4gag:P, 4wht:a, 4wht:i, 4wht:m, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14615 4wht:H
    (2.22)
    BS01 >4wht:g (identical to 4gag:P, 4wht:a, 4wht:i, 4wht:m, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14616 4wht:I
    (2.22)
    BS01 >4wht:i (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:m, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14617 4wht:J
    (2.22)
    BS01 >4wht:i (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:m, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14618 4wht:K
    (2.22)
    BS01 >4wht:k (identical to 4wht:c, 4wht:e, 4wht:s, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14619 4wht:L
    (2.22)
    BS01 >4wht:k (identical to 4wht:c, 4wht:e, 4wht:s, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14620 4wht:M
    (2.22)
    BS01 >4wht:m (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:i, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14621 4wht:N
    (2.22)
    BS01 >4wht:m (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:i, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14622 4wht:O
    (2.22)
    BS01 >4wht:o
    LINTNGSWHVN
    N/A N/A N/A 25473061
    14623 4wht:P
    (2.22)
    BS01 >4wht:o
    LINTNGSWHVN
    N/A N/A N/A 25473061
    14624 4wht:Q
    (2.22)
    BS01 >4wht:q (identical to 5vxr:P, 4wht:u)
    LINTNGSWHV
    N/A N/A N/A 25473061
    14625 4wht:R
    (2.22)
    BS01 >4wht:m (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:i, 4wht:x)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14626 4wht:R
    (2.22)
    BS02 >4wht:q (identical to 5vxr:P, 4wht:u)
    LINTNGSWHV
    N/A N/A N/A 25473061
    14627 4wht:S
    (2.22)
    BS01 >4wht:s (identical to 4wht:c, 4wht:e, 4wht:k, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14628 4wht:T
    (2.22)
    BS01 >4wht:s (identical to 4wht:c, 4wht:e, 4wht:k, 4why:A, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14629 4wht:U
    (2.22)
    BS01 >4wht:u (identical to 5vxr:P, 4wht:q)
    LINTNGSWHV
    N/A N/A N/A 25473061
    14630 4wht:V
    (2.22)
    BS01 >4wht:u (identical to 5vxr:P, 4wht:q)
    LINTNGSWHV
    N/A N/A N/A 25473061
    14631 4wht:X
    (2.22)
    BS01 >4wht:x (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:i, 4wht:m)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14632 4wht:Y
    (2.22)
    BS01 >4wht:x (identical to 4gag:P, 4wht:a, 4wht:g, 4wht:i, 4wht:m)
    QLINTNGSWHVN
    N/A N/A N/A 25473061
    14633 4why:G
    (2.62)
    BS01 >4why:D (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:C)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14634 4why:H
    (2.62)
    BS01 >4why:D (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:C)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14635 4why:I
    (2.62)
    BS01 >4why:A (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14636 4why:J
    (2.62)
    BS01 >4why:A (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:B, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14637 4why:K
    (2.62)
    BS01 >4why:C (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14638 4why:L
    (2.62)
    BS01 >4why:C (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:B, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14639 4why:M
    (2.62)
    BS01 >4why:B (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14640 4why:N
    (2.62)
    BS01 >4why:B (identical to 4wht:c, 4wht:e, 4wht:k, 4wht:s, 4why:A, 4why:C, 4why:D)
    QLINTNGSWHV
    N/A N/A N/A 25473061
    14641 4wih:A
    (1.139)
    BS01 >4wih:B
    IAAGRTGRRQAIHDI
    2.7.11.11 GO:0000287 ... P25321 26249705
    14642 4wj5:A
    (1.65)
    BS01 >4wj5:C (identical to 4wj5:F)
    IPAGIGILTP
    ? N/A P04439 25311806
    14643 4wj5:D
    (1.65)
    BS01 >4wj5:F (identical to 4wj5:C)
    IPAGIGILTP
    ? N/A P04439 25311806
    14644 4wj7:A
    (2.753)
    BS01 >4wj7:W (identical to 4wj7:Y, 4wj7:Z)
    VDKVVINPYFG
    ? N/A Q9BSQ5 25525273
    14645 4wj7:B
    (2.753)
    BS01 >4wj7:X
    VDKVVINPYFGL
    ? N/A Q9BSQ5 25525273
    14646 4wj7:C
    (2.753)
    BS01 >4wj7:Y (identical to 4wj7:W, 4wj7:Z)
    VDKVVINPYFG
    ? N/A Q9BSQ5 25525273
    14647 4wj7:D
    (2.753)
    BS01 >4wj7:Z (identical to 4wj7:W, 4wj7:Y)
    VDKVVINPYFG
    ? N/A Q9BSQ5 25525273
    14648 4wjn:A
    (1.5)
    BS01 >4wjn:B (identical to 6uyt:B)
    AEERVVVISSSNSSSRY
    ? N/A P63165 25497731
    14649 4wjo:A
    (1.46)
    BS01 >4wjo:B (identical to 8dji:B, 6uyp:B, 6uyq:B)
    AEERVVVISNSSSRY
    ? N/A P63165 25497731
    14650 4wjp:A
    (1.7)
    BS01 >4wjp:B (identical to 6uyy:B)
    EAEERIIVLSD
    ? N/A P63165 25497731
    14651 4wjp:C
    (1.7)
    BS01 >4wjp:D (identical to 4wjq:D)
    AEERIIVLSDSD
    ? N/A P63165 25497731
    14652 4wjq:A
    (1.35)
    BS01 >4wjq:B
    SGEAEERIIVLS
    ? N/A P63165 25497731
    14653 4wjq:C
    (1.35)
    BS01 >4wjq:D (identical to 4wjp:D)
    AEERIIVLSDSD
    ? N/A P63165 25497731
    14654 4wjv:A
    (3.2)
    BS01 >4wjv:K
    DALPTYLLDREQ
    ? N/A P25382 25404745
    14655 4wjv:B
    (3.2)
    BS01 >4wjv:L (identical to 4wjv:I, 4wjv:J)
    DALPTYLLDRE
    ? N/A P25382 25404745
    14656 4wjv:C
    (3.2)
    BS01 >4wjv:I (identical to 4wjv:J, 4wjv:L)
    DALPTYLLDRE
    ? N/A P25382 25404745
    14657 4wjv:D
    (3.2)
    BS01 >4wjv:J (identical to 4wjv:I, 4wjv:L)
    DALPTYLLDRE
    ? N/A P25382 25404745
    14658 4wjw:B
    (2.59)
    BS01 >4wjw:P
    YYLNLNQDEESLLR
    ? GO:0003674 ... P40955 25364754
    14659 4wk0:A
    (1.78)
    BS01 >4wk0:C (identical to 3vi4:I)
    RGD
    ? GO:0007155 ... P08648 25475857
    14660 4wk0:B
    (1.78)
    BS01 >4wk0:C (identical to 3vi4:I)
    RGD
    ? N/A P05556 25475857
    14661 4wk2:A
    (2.5)
    BS01 >4wk2:C (identical to 3zdy:I, 3zdz:I, 3ze0:I, 3ze0:J, 3ze1:I, 3ze1:J, 3ze2:I, 3ze2:J)
    GRGDSP
    ? GO:0007155 ... P08648 25475857
    14662 4wk2:B
    (2.5)
    BS01 >4wk2:C (identical to 3zdy:I, 3zdz:I, 3ze0:I, 3ze0:J, 3ze1:I, 3ze1:J, 3ze2:I, 3ze2:J)
    GRGDSP
    ? N/A P05556 25475857
    14663 4wk4:A
    (2.5)
    BS01 >4wk4:C
    ACRGDGWC
    ? GO:0007155 ... P08648 25475857
    14664 4wk4:B
    (2.5)
    BS01 >4wk4:C
    ACRGDGWC
    ? N/A P05556 25475857
    14665 4wkm:A
    (2.15)
    BS01 >4wkm:I (identical to 6fbt:E, 6fcs:B, 4wkm:J, 4wkm:K, 4wkm:L, 4wkm:M, 4wkm:N, 4wkm:O, 4wkm:P)
    AEtAA
    N/A N/A N/A 25480792
    14666 4wkm:B
    (2.15)
    BS01 >4wkm:J (identical to 6fbt:E, 6fcs:B, 4wkm:I, 4wkm:K, 4wkm:L, 4wkm:M, 4wkm:N, 4wkm:O, 4wkm:P)
    AEtAA
    N/A N/A N/A 25480792
    14667 4wkm:C
    (2.15)
    BS01 >4wkm:K (identical to 6fbt:E, 6fcs:B, 4wkm:I, 4wkm:J, 4wkm:L, 4wkm:M, 4wkm:N, 4wkm:O, 4wkm:P)
    AEtAA
    N/A N/A N/A 25480792
    14668 4wkm:D
    (2.15)
    BS01 >4wkm:L (identical to 6fbt:E, 6fcs:B, 4wkm:I, 4wkm:J, 4wkm:K, 4wkm:M, 4wkm:N, 4wkm:O, 4wkm:P)
    AEtAA
    N/A N/A N/A 25480792
    14669 4wkm:E
    (2.15)
    BS01 >4wkm:M (identical to 6fbt:E, 6fcs:B, 4wkm:I, 4wkm:J, 4wkm:K, 4wkm:L, 4wkm:N, 4wkm:O, 4wkm:P)
    AEtAA
    N/A N/A N/A 25480792
    14670 4wkm:F
    (2.15)
    BS01 >4wkm:N (identical to 6fbt:E, 6fcs:B, 4wkm:I, 4wkm:J, 4wkm:K, 4wkm:L, 4wkm:M, 4wkm:O, 4wkm:P)
    AEtAA
    N/A N/A N/A 25480792
    14671 4wkm:G
    (2.15)
    BS01 >4wkm:O (identical to 6fbt:E, 6fcs:B, 4wkm:I, 4wkm:J, 4wkm:K, 4wkm:L, 4wkm:M, 4wkm:N, 4wkm:P)
    AEtAA
    N/A N/A N/A 25480792
    14672 4wkm:H
    (2.15)
    BS01 >4wkm:P (identical to 6fbt:E, 6fcs:B, 4wkm:I, 4wkm:J, 4wkm:K, 4wkm:L, 4wkm:M, 4wkm:N, 4wkm:O)
    AEtAA
    N/A N/A N/A 25480792
    14673 4wlb:A
    (1.702)
    BS01 >4wlb:D (identical to 4wlb:E)
    SLLKKLLD
    ? GO:0003677 ... P51449 25453817
    14674 4wlb:B
    (1.702)
    BS01 >4wlb:E (identical to 4wlb:D)
    SLLKKLLD
    ? GO:0003677 ... P51449 25453817
    14675 4wnd:A
    (1.5)
    BS01 >4wnd:B
    QLLHSDHMEMEPETMETKSVTDYFSK
    ? N/A P81274 25664792
    14676 4wne:A
    (2.0)
    BS01 >4wne:B
    DHMEMEPETMETKSVTDYF
    ? N/A P81274 25664792
    14677 4wnf:A
    (2.9)
    BS01 >4wnf:B (identical to 4wng:B)
    HMEMEPETMETKSVTDYF
    ? N/A P81274 25664792
    14678 4wng:A
    (2.11)
    BS01 >4wng:B (identical to 4wnf:B)
    HMEMEPETMETKSVTDYF
    ? N/A P81274 25664792
    14679 4wnl:A
    (2.8)
    BS01 >4wnl:H
    VLPGVK
    ? GO:0003723 ... P36068 25535369
    14680 4wnl:B
    (2.8)
    BS01 >4wnl:G (identical to 4wnl:E, 4wnl:F)
    PVLPGVKR
    ? GO:0003723 ... P36068 25535369
    14681 4wnl:C
    (2.8)
    BS01 >4wnl:F (identical to 4wnl:E, 4wnl:G)
    PVLPGVKR
    ? GO:0003723 ... P36068 25535369
    14682 4wnl:D
    (2.8)
    BS01 >4wnl:E (identical to 4wnl:F, 4wnl:G)
    PVLPGVKR
    ? GO:0003723 ... P36068 25535369
    14683 4wnn:D
    (1.8)
    BS01 >4wnn:T
    EEVSEY
    ? GO:0000786 ... P02293 26455391
    14684 4wpf:A
    (2.202)
    BS01 >4wpf:B (identical to 4wpf:E)
    AHKILHRLLQE
    ? GO:0003677 ... P51449 25815138
    14685 4wpf:D
    (2.202)
    BS01 >4wpf:E (identical to 4wpf:B)
    AHKILHRLLQE
    ? GO:0003677 ... P51449 25815138
    14686 4wph:A
    (2.92)
    BS01 >4wph:D
    PRKCARKTR
    3.4.19.12 N/A Q93009 26046769
    14687 4wph:B
    (2.92)
    BS01 >4wph:C (identical to 4wpi:C, 4wpi:D)
    GPRKCARKTR
    3.4.19.12 N/A Q93009 26046769
    14688 4wpi:A
    (3.4)
    BS01 >4wpi:D (identical to 4wph:C, 4wpi:C)
    GPRKCARKTR
    3.4.19.12 N/A Q93009 26046769
    14689 4wpi:B
    (3.4)
    BS01 >4wpi:C (identical to 4wph:C, 4wpi:D)
    GPRKCARKTR
    3.4.19.12 N/A Q93009 26046769
    14690 4wqp:A
    (1.99)
    BS01 >4wqp:P (identical to 5apk:D)
    VERLQIFQHLHPI
    ? GO:0003677 ... P51449 25815138
    14691 4wqp:B
    (1.99)
    BS01 >4wqp:P (identical to 5apk:D)
    VERLQIFQHLHPI
    ? GO:0003677 ... P51449 25815138
    14692 4wqu:BL
    (2.8)
    BS02 >4wqu:BX (identical to 4v9r:AW, 4v9r:CW, 4v9s:AW, 4v9s:CW, 4wqu:DX)
    TVIPVVPYVY
    ? GO:0000049 ... Q5SHN3 25594181
    14693 4wqu:DL
    (2.8)
    BS02 >4wqu:DX (identical to 4v9r:AW, 4v9r:CW, 4v9s:AW, 4v9s:CW, 4wqu:BX)
    TVIPVVPYVY
    ? GO:0000049 ... Q5SHN3 25594181
    14694 4wrq:A
    (2.409)
    BS01 >4wrq:C
    SASLSNL
    ? GO:0000122 ... P63104 25909186
    14695 4wrq:B
    (2.409)
    BS01 >4wrq:D
    SASLSNLH
    ? GO:0000122 ... P63104 25909186
    14696 4wsf:A
    (1.501)
    BS01 >4wsf:B
    VVFKKPLAPAP
    ? GO:0019888 ... Q9VFS5 25562660
    14697 4wsi:A
    (2.95)
    BS01 >4wsi:X (identical to 4wsi:Y)
    PRLEMDNVLKPPPEERLI
    ? N/A Q8N3R9 25385611
    14698 4wsi:B
    (2.95)
    BS01 >4wsi:Y (identical to 4wsi:X)
    PRLEMDNVLKPPPEERLI
    ? N/A Q8N3R9 25385611
    14699 4wu5:A
    (2.4)
    BS01 >4wu5:C (identical to 8gvb:P, 8gvi:P, 5hgb:C, 5hgb:F, 5hgb:I, 5hgb:L, 7k80:C, 7k80:F, 7k81:C, 4wu5:F)
    RYPLTFGW
    ? N/A P04439 N/A
    14700 4wu5:D
    (2.4)
    BS01 >4wu5:F (identical to 8gvb:P, 8gvi:P, 5hgb:C, 5hgb:F, 5hgb:I, 5hgb:L, 7k80:C, 7k80:F, 7k81:C, 4wu5:C)
    RYPLTFGW
    ? N/A P04439 N/A

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218