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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 197122 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    18001 1x61:A (-1.00) BS01 ZN ? N/A Q15654 N/A
    18002 1x61:A (-1.00) BS02 ZN ? N/A Q15654 N/A
    18003 1x62:A (-1.00) BS01 ZN ? N/A O00151 N/A
    18004 1x62:A (-1.00) BS02 ZN ? N/A O00151 N/A
    18005 1x63:A (-1.00) BS01 ZN ? GO:0007517 ... Q13642 N/A
    18006 1x63:A (-1.00) BS02 ZN ? GO:0007517 ... Q13642 N/A
    18007 1x64:A (-1.00) BS01 ZN ? N/A O70209 N/A
    18008 1x64:A (-1.00) BS02 ZN ? N/A O70209 N/A
    18009 1x6e:A (-1.00) BS01 ZN ? N/A P17028 N/A
    18010 1x6e:A (-1.00) BS02 ZN ? N/A P17028 N/A
    18011 1x6f:A (-1.00) BS01 ZN ? N/A Q96JM2 N/A
    18012 1x6h:A (-1.00) BS01 ZN ? N/A P49711 N/A
    18013 1x6h:A (-1.00) BS02 ZN ? N/A P49711 N/A
    18014 1x6m:A (2.35) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18015 1x6m:A (2.35) BS02 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18016 1x6m:B (2.35) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18017 1x6m:B (2.35) BS02 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18018 1x6m:C (2.35) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18019 1x6m:C (2.35) BS02 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18020 1x6m:D (2.35) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18021 1x6m:D (2.35) BS02 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18022 1x7i:B (1.7) BS01 CA ? GO:0005507 ... P67825 15624211
    18023 1x7n:A (1.89) BS01 MN 5.3.1.9 GO:0004347 ... P83194 15465052
    18024 1x7w:A (1.73) BS01 MN 1.2.4.4 GO:0003863 ... P12694 15576032
    18025 1x7x:A (2.1) BS01 MN 1.2.4.4 GO:0003863 ... P12694 15576032
    18026 1x7y:A (1.57) BS01 MN 1.2.4.4 GO:0003863 ... P12694 15576032
    18027 1x7z:A (1.72) BS01 MN 1.2.4.4 GO:0003863 ... P12694 15576032
    18028 1x80:A (2.0) BS01 MN 1.2.4.4 GO:0003863 ... P12694 15576032
    18029 1x81:B (3.5) BS01 ZN 2.5.1.58 GO:0003824 ... Q02293 15454228
    18030 1x83:A (1.8) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    18031 1x83:A (1.8) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    18032 1x83:B (1.8) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    18033 1x83:B (1.8) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    18034 1x84:A (1.78) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    18035 1x84:A (1.78) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    18036 1x84:B (1.78) BS01 MN 5.3.3.2 GO:0000287 ... Q46822 15643873
    18037 1x84:B (1.78) BS02 MG 5.3.3.2 GO:0000287 ... Q46822 15643873
    18038 1x8b:A (1.81) BS01 MG 2.7.10.2 GO:0004672 ... P30291 15837193
    18039 1x8b:A (1.81) BS02 MG 2.7.10.2 GO:0004672 ... P30291 15837193
    18040 1x8c:B (2.1) BS01 CA ? GO:0005507 ... P67825 15624211
    18041 1x8g:A (1.7) BS01 ZN 3.5.2.6 GO:0008270 ... P26918 15588826
    18042 1x8h:A (1.6) BS01 ZN 3.5.2.6 GO:0008270 ... P26918 15588826
    18043 1x8i:A (1.9) BS01 ZN 3.5.2.6 GO:0008270 ... P26918 15588826
    18044 1x8j:A (2.35) BS01 CA ? GO:0005737 ... Q26490 15608121
    18045 1x8j:B (2.35) BS02 CA ? GO:0005737 ... Q26490 15608121
    18046 1x8k:A (2.75) BS01 CA ? GO:0005737 ... Q26490 15608121
    18047 1x8k:B (2.75) BS01 CA ? GO:0005737 ... Q26490 15608121
    18048 1x8l:A (2.1) BS01 CA ? GO:0005737 ... Q26490 15608121
    18049 1x8l:B (2.1) BS01 CA ? GO:0005737 ... Q26490 15608121
    18050 1x9l:A (-1.00) BS01 CU1 ? N/A Q9RT80 15753304
    18051 1x9r:A (1.9) BS01 CU ? GO:0009055 ... P42849 15631465
    18052 1x9r:B (1.9) BS01 CU ? GO:0009055 ... P42849 15631465
    18053 1x9u:A (1.8) BS01 CU ? GO:0009055 ... P42849 15631465
    18054 1x9u:B (1.8) BS01 CU ? GO:0009055 ... P42849 15631465
    18055 1xa5:A (2.12) BS01 CA ? GO:0000922 ... P62157 15596444
    18056 1xa5:A (2.12) BS02 CA ? GO:0000922 ... P62157 15596444
    18057 1xa5:A (2.12) BS03 CA ? GO:0000922 ... P62157 15596444
    18058 1xa5:A (2.12) BS04 CA ? GO:0000922 ... P62157 15596444
    18059 1xa6:A (3.2) BS01 ZN ? GO:0005096 ... P52757 15507211
    18060 1xa6:A (3.2) BS02 ZN ? GO:0005096 ... P52757 15507211
    18061 1xa8:A (2.4) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18062 1xa8:B (2.4) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18063 1xa8:C (2.4) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18064 1xa8:D (2.4) BS01 ZN 4.4.1.22 GO:0008270 ... Q51669 15548539
    18065 1xaf:A (2.01) BS01 ZN 2.4.2.1
    2.4.2.28
    3.5.4.4
    GO:0004000 ... A0A384KG77 16498617
    18066 1xaf:A (2.01) BS02 ZN 2.4.2.1
    2.4.2.28
    3.5.4.4
    GO:0004000 ... A0A384KG77 16498617
    18067 1xaf:B (2.01) BS01 ZN 2.4.2.1
    2.4.2.28
    3.5.4.4
    GO:0004000 ... A0A384KG77 16498617
    18068 1xaf:B (2.01) BS02 ZN 2.4.2.1
    2.4.2.28
    3.5.4.4
    GO:0004000 ... A0A384KG77 16498617
    18069 1xag:A (2.45) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18070 1xah:A (2.2) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18071 1xah:B (2.2) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18072 1xai:A (2.3) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18073 1xai:B (2.3) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18074 1xaj:A (2.35) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18075 1xaj:B (2.35) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18076 1xal:A (2.8) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18077 1xal:B (2.8) BS01 ZN 4.2.3.4 GO:0000166 ... Q6GGU4 15465043
    18078 1xb0:A (2.2) BS02 ZN ? N/A Q96P09 15485395
    18079 1xb0:A (2.2) BS03 ZN ? N/A Q96P09 15485395
    18080 1xb0:B (2.2) BS02 ZN ? N/A Q96P09 15485395
    18081 1xb0:B (2.2) BS03 ZN ? N/A Q96P09 15485395
    18082 1xb0:B (2.2) BS04 ZN ? N/A Q96P09 15485395
    18083 1xb0:C (2.2) BS02 ZN ? N/A Q96P09 15485395
    18084 1xb0:C (2.2) BS03 ZN ? N/A Q96P09 15485395
    18085 1xb0:D (2.2) BS02 ZN ? N/A Q96P09 15485395
    18086 1xb0:D (2.2) BS03 ZN ? N/A Q96P09 15485395
    18087 1xb0:E (2.2) BS02 ZN ? N/A Q96P09 15485395
    18088 1xb0:E (2.2) BS03 ZN ? N/A Q96P09 15485395
    18089 1xb0:F (2.2) BS02 ZN ? N/A Q96P09 15485395
    18090 1xb0:F (2.2) BS03 ZN ? N/A Q96P09 15485395
    18091 1xb0:F (2.2) BS04 ZN ? N/A Q96P09 15485395
    18092 1xb1:A (2.7) BS02 ZN ? N/A Q96P09 15485395
    18093 1xb1:A (2.7) BS03 ZN ? N/A Q96P09 15485395
    18094 1xb1:B (2.7) BS02 ZN ? N/A Q96P09 15485395
    18095 1xb1:B (2.7) BS03 ZN ? N/A Q96P09 15485395
    18096 1xb1:C (2.7) BS02 ZN ? N/A Q96P09 15485395
    18097 1xb1:C (2.7) BS03 ZN ? N/A Q96P09 15485395
    18098 1xb1:D (2.7) BS02 ZN ? N/A Q96P09 15485395
    18099 1xb1:D (2.7) BS03 ZN ? N/A Q96P09 15485395
    18100 1xb1:E (2.7) BS02 ZN ? N/A Q96P09 15485395
    18101 1xb1:E (2.7) BS03 ZN ? N/A Q96P09 15485395
    18102 1xb1:E (2.7) BS04 ZN ? N/A Q96P09 15485395
    18103 1xb1:F (2.7) BS02 ZN ? N/A Q96P09 15485395
    18104 1xb1:F (2.7) BS03 ZN ? N/A Q96P09 15485395
    18105 1xb3:A (1.501) BS01 CU ? GO:0005507 ... P00282 15449946
    18106 1xb3:B (1.501) BS01 CU ? GO:0005507 ... P00282 15449946
    18107 1xb6:A (1.823) BS01 CU ? GO:0005507 ... P00282 15449946
    18108 1xb6:B (1.823) BS01 CU ? GO:0005507 ... P00282 15449946
    18109 1xb8:A (2.0) BS01 ZN ? GO:0005507 ... P00282 15449946
    18110 1xb8:C (2.0) BS01 ZN ? GO:0005507 ... P00282 15449946
    18111 1xbt:A (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18112 1xbt:B (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18113 1xbt:C (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18114 1xbt:D (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18115 1xbt:E (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18116 1xbt:F (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18117 1xbt:G (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18118 1xbt:H (2.4) BS01 ZN 2.7.1.21 GO:0004797 ... P04183 15611477
    18119 1xbu:A (1.2) BS01 ZN 3.4.11.24 GO:0004177 ... P80561 N/A
    18120 1xbu:A (1.2) BS02 ZN 3.4.11.24 GO:0004177 ... P80561 N/A
    18121 1xbu:A (1.2) BS03 CA 3.4.11.24 GO:0004177 ... P80561 N/A
    18122 1xbv:A (1.66) BS02 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18123 1xbv:B (1.66) BS02 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18124 1xbx:A (1.81) BS02 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18125 1xbx:B (1.81) BS02 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18126 1xby:A (1.58) BS02 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18127 1xby:B (1.58) BS02 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18128 1xbz:A (1.8) BS01 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18129 1xbz:A (1.8) BS02 MG 4.1.1.85 GO:0000287 ... P39304 15697207
    18130 1xc3:A (2.1) BS01 ZN 2.7.1.4 GO:0000272 ... O05510 21185308
    18131 1xc8:A (1.95) BS03 ZN 3.2.2.23
    4.2.99.18
    GO:0003676 ... P42371 15249553
    18132 1xcb:D (2.9) BS02 CA ? GO:0003677 ... Q9X2V5 15642260
    18133 1xcp:A (3.2) BS01 MG 1.18.6.1 GO:0005524 ... P00459 15650336
    18134 1xcp:B (3.2) BS01 MG 1.18.6.1 GO:0005524 ... P00459 15650336
    18135 1xcp:C (3.2) BS01 MG 1.18.6.1 GO:0005524 ... P00459 15650336
    18136 1xcp:D (3.2) BS02 MG 1.18.6.1 GO:0005524 ... P00459 15650336
    18137 1xcr:A (1.7) BS01 ZN 3.1.-.- GO:0005515 ... Q9H0W9 16522806
    18138 1xcr:B (1.7) BS01 ZN 3.1.-.- GO:0005515 ... Q9H0W9 16522806
    18139 1xcw:A (2.0) BS03 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    18140 1xcx:A (1.9) BS03 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    18141 1xd0:A (2.0) BS02 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    18142 1xd1:A (2.2) BS02 CA 3.2.1.1 GO:0003824 ... P04746 15736945
    18143 1xd2:A (2.7) BS01 MG 3.6.5.2 GO:0003924 ... P01112 15507210
    18144 1xd3:A (1.45) BS01 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    18145 1xd3:A (1.45) BS02 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    18146 1xd3:C (1.45) BS01 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    18147 1xd3:C (1.45) BS02 MG 3.4.19.12 GO:0004843 ... P15374 15531586
    18148 1xd9:A (2.8) BS01 MG 1.18.6.1 GO:0005524 ... P00459 15549494
    18149 1xd9:B (2.8) BS02 MG 1.18.6.1 GO:0005524 ... P00459 15549494
    18150 1xdc:A (1.85) BS01 MN 1.15.1.1 GO:0004784 ... P04179 16150974
    18151 1xdc:B (1.85) BS01 MN 1.15.1.1 GO:0004784 ... P04179 16150974
    18152 1xdd:A (2.2) BS01 MG ? N/A P20701 15304496
    18153 1xdd:B (2.2) BS02 MG ? N/A P20701 15304496
    18154 1xdg:A (2.1) BS01 MG ? N/A P20701 15304496
    18155 1xdg:B (2.1) BS02 MG ? N/A P20701 15304496
    18156 1xdj:A (2.2) BS01 ZN 2.1.1.14 GO:0003871 ... Q9X112 15630480
    18157 1xdj:B (2.2) BS01 ZN 2.1.1.14 GO:0003871 ... Q9X112 15630480
    18158 1xdp:A (2.5) BS01 MG 2.7.4.1 GO:0003824 ... P0A7B1 15947782
    18159 1xdp:A (2.5) BS02 MG 2.7.4.1 GO:0003824 ... P0A7B1 15947782
    18160 1xe4:A (1.95) BS01 MG 2.3.2.10 GO:0008360 ... Q9EY50 15901708
    18161 1xed:A (1.9) BS01 MG ? N/A P01833 15530357
    18162 1xed:B (1.9) BS01 MG ? N/A P01833 15530357
    18163 1xeg:A (1.81) BS02 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 18323598
    18164 1xem:A (1.76) BS01 ZN 3.5.1.88 GO:0005515 ... P0A6K3 15796505
    18165 1xen:A (1.85) BS01 FE 3.5.1.88 GO:0005515 ... P0A6K3 15796505
    18166 1xeo:A (1.3) BS01 CO 3.5.1.88 GO:0005515 ... P0A6K3 15796505
    18167 1xer:A (2.0) BS01 ZN ? GO:0008270 ... P55907 8836097
    18168 1xev:A (2.2) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 N/A
    18169 1xev:B (2.2) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 N/A
    18170 1xev:C (2.2) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 N/A
    18171 1xev:D (2.2) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 N/A
    18172 1xex:A (2.5) BS01 MG ? N/A Q8TZY2 15458651
    18173 1xf1:A (1.9) BS01 CA 3.4.21.110 GO:0004252 ... P15926 16344483
    18174 1xf1:B (1.9) BS01 CA 3.4.21.110 GO:0004252 ... P15926 16344483
    18175 1xf8:A (1.9) BS01 MG 2.3.2.10 GO:0008360 ... Q9EY50 15901708
    18176 1xf9:B (2.7) BS01 MG 5.6.1.6 GO:0005524 ... P26361 15619636
    18177 1xf9:C (2.7) BS01 MG 5.6.1.6 GO:0005524 ... P26361 15619636
    18178 1xf9:D (2.7) BS01 MG 5.6.1.6 GO:0005524 ... P26361 15619636
    18179 1xf9:D (2.7) BS02 MG 5.6.1.6 GO:0005524 ... P26361 15619636
    18180 1xfa:A (3.1) BS01 MG 5.6.1.6 GO:0005524 ... P26361 15619636
    18181 1xfa:B (3.1) BS02 MG 5.6.1.6 GO:0005524 ... P26361 15619636
    18182 1xfe:A (-1.00) BS01 CA ? GO:0005509 ... P01130 15494314
    18183 1xfe:A (-1.00) BS02 CA ? GO:0005509 ... P01130 15494314
    18184 1xfi:A (1.7) BS01 MG 3.1.3.- GO:0004594 ... Q949P3 16511115
    18185 1xfo:A (1.96) BS01 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18186 1xfo:A (1.96) BS02 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18187 1xfo:B (1.96) BS01 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18188 1xfo:B (1.96) BS02 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18189 1xfo:C (1.96) BS01 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18190 1xfo:C (1.96) BS02 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18191 1xfo:D (1.96) BS01 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18192 1xfo:D (1.96) BS02 ZN 3.4.11.- GO:0004177 ... O59196 15375159
    18193 1xfu:A (3.35) BS01 MG 4.6.1.1 GO:0003824 ... P40136 15719022
    18194 1xfu:B (3.35) BS01 MG 4.6.1.1 GO:0003824 ... P40136 15719022
    18195 1xfu:C (3.35) BS01 MG 4.6.1.1 GO:0003824 ... P40136 15719022
    18196 1xfu:D (3.35) BS01 MG 4.6.1.1 GO:0003824 ... P40136 15719022
    18197 1xfu:E (3.35) BS01 MG 4.6.1.1 GO:0003824 ... P40136 15719022
    18198 1xfu:F (3.35) BS01 MG 4.6.1.1 GO:0003824 ... P40136 15719022
    18199 1xfu:O (3.35) BS01 CA ? GO:0000086 ... P0DP23 15719022
    18200 1xfu:O (3.35) BS02 CA ? GO:0000086 ... P0DP23 15719022

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218