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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 197122 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    13801 1s1d:B (1.6) BS01 CA 3.6.1.6 GO:0005509 ... Q8WVQ1 15006348
    13802 1s1e:A (2.3) BS01 CA ? GO:0005267 ... Q9NZI2 14980207
    13803 1s1e:A (2.3) BS02 CA ? GO:0005267 ... Q9NZI2 14980207
    13804 1s1g:A (2.6) BS01 ZN ? GO:0005249 ... Q9UK17 14980207
    13805 1s1g:B (2.6) BS01 ZN ? GO:0005249 ... Q9UK17 14980207
    13806 1s1m:A (2.3) BS01 MG 6.3.4.2 GO:0000287 ... P0A7E5 15157079
    13807 1s1m:B (2.3) BS01 MG 6.3.4.2 GO:0000287 ... P0A7E5 15157079
    13808 1s1q:A (2.0) BS01 CU ? GO:0015031 ... Q99816 15053872
    13809 1s1q:C (2.0) BS01 CU ? GO:0015031 ... Q99816 15053872
    13810 1s24:A (-1.00) BS01 CD ? GO:0005506 ... P00272 15023067
    13811 1s26:D (3.0) BS01 CA ? GO:0000086 ... P0DP23 15063758
    13812 1s26:D (3.0) BS02 CA ? GO:0000086 ... P0DP23 15063758
    13813 1s26:E (3.0) BS01 CA ? GO:0000086 ... P0DP23 15063758
    13814 1s26:E (3.0) BS02 CA ? GO:0000086 ... P0DP23 15063758
    13815 1s26:F (3.0) BS01 CA ? GO:0000086 ... P0DP23 15063758
    13816 1s26:F (3.0) BS02 CA ? GO:0000086 ... P0DP23 15063758
    13817 1s2n:A (2.44) BS01 CA 3.4.21.- GO:0004252 ... Q8GB52 15670163
    13818 1s2n:A (2.44) BS02 CA 3.4.21.- GO:0004252 ... Q8GB52 15670163
    13819 1s2n:A (2.44) BS03 CA 3.4.21.- GO:0004252 ... Q8GB52 15670163
    13820 1s2n:B (2.44) BS01 CA 3.4.21.- GO:0004252 ... Q8GB52 15670163
    13821 1s2n:B (2.44) BS02 CA 3.4.21.- GO:0004252 ... Q8GB52 15670163
    13822 1s2n:B (2.44) BS03 CA 3.4.21.- GO:0004252 ... Q8GB52 15670163
    13823 1s2o:A (1.4) BS01 MG 3.1.3.24 GO:0000287 ... P74325 15937230
    13824 1s2z:A (1.75) BS01 FE ? GO:0005506 ... P24931 15134924
    13825 1s2z:A (1.75) BS02 ZN ? GO:0005506 ... P24931 15134924
    13826 1s2z:A (1.75) BS03 FE ? GO:0005506 ... P24931 15134924
    13827 1s30:A (2.05) BS01 FE ? GO:0005506 ... P24931 15134924
    13828 1s30:A (2.05) BS02 ZN ? GO:0005506 ... P24931 15134924
    13829 1s30:A (2.05) BS03 FE ? GO:0005506 ... P24931 15134924
    13830 1s38:A (1.81) BS01 ZN 2.4.2.29 GO:0002099 ... P28720 N/A
    13831 1s39:A (1.95) BS01 ZN 2.4.2.29 GO:0002099 ... P28720 N/A
    13832 1s3g:A (2.25) BS01 ZN 2.7.4.3 GO:0004017 ... P84139 15100224
    13833 1s3h:A (2.5) BS01 CO 2.1.3.1 GO:0003824 ... Q70AC7 15329673
    13834 1s3n:A (2.5) BS01 MN 3.1.4.- GO:0016787 ... Q58346 15128743
    13835 1s3n:A (2.5) BS02 MN 3.1.4.- GO:0016787 ... Q58346 15128743
    13836 1s3n:B (2.5) BS01 MN 3.1.4.- GO:0016787 ... Q58346 15128743
    13837 1s3n:B (2.5) BS02 MN 3.1.4.- GO:0016787 ... Q58346 15128743
    13838 1s3p:A (2.0) BS01 CA ? GO:0005509 ... P02625 15287728
    13839 1s3p:A (2.0) BS02 CA ? GO:0005509 ... P02625 15287728
    13840 1s3q:A (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13841 1s3q:A (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13842 1s3q:B (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13843 1s3q:B (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13844 1s3q:C (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13845 1s3q:C (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13846 1s3q:D (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13847 1s3q:D (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13848 1s3q:E (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13849 1s3q:E (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13850 1s3q:F (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13851 1s3q:F (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13852 1s3q:G (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13853 1s3q:G (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13854 1s3q:H (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13855 1s3q:H (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13856 1s3q:I (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13857 1s3q:I (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13858 1s3q:J (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13859 1s3q:J (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13860 1s3q:K (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13861 1s3q:K (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13862 1s3q:L (2.1) BS01 ZN ? GO:0004322 ... O29424 15837202
    13863 1s3q:L (2.1) BS02 ZN ? GO:0004322 ... O29424 15837202
    13864 1s3x:A (1.84) BS02 CA ? GO:0005524 ... P0DMV8 9083109
    13865 1s4b:P (2.0) BS01 ZN 3.4.24.15 GO:0000209 ... P52888 14998993
    13866 1s4c:A (2.2) BS01 CU ? GO:0005737 ... P44583 16077096
    13867 1s4c:B (2.2) BS01 CU ? GO:0005737 ... P44583 16077096
    13868 1s4c:C (2.2) BS01 CU ? GO:0005737 ... P44583 16077096
    13869 1s4c:D (2.2) BS01 CU ? GO:0005737 ... P44583 16077096
    13870 1s4i:A (1.8) BS01 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13871 1s4i:A (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13872 1s4i:B (1.8) BS01 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13873 1s4i:B (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13874 1s4i:C (1.8) BS01 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13875 1s4i:C (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13876 1s4i:D (1.8) BS01 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13877 1s4i:D (1.8) BS02 ZN 1.15.1.1 GO:0004784 ... O31851 15897454
    13878 1s4o:A (2.01) BS01 MN 2.4.1.- GO:0000030 ... P27809 14752117
    13879 1s4o:B (2.01) BS01 MN 2.4.1.- GO:0000030 ... P27809 14752117
    13880 1s4p:A (2.01) BS02 MN 2.4.1.- GO:0000030 ... P27809 14752117
    13881 1s4p:B (2.01) BS02 MN 2.4.1.- GO:0000030 ... P27809 14752117
    13882 1s5g:Y (3.1) BS01 MG ? GO:0005509 ... P13543 15184651
    13883 1s5g:Z (3.1) BS01 CA ? GO:0005509 ... P07291 15184651
    13884 1s5j:A (2.4) BS01 MG 2.7.7.7 GO:0000166 ... P26811 15530364
    13885 1s5l:A (3.5) BS01 FE 1.10.3.9 GO:0005506 ... P0A444 14764885
    13886 1s5l:D (3.5) BS01 FE 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    13887 1s5l:a (3.5) BS01 FE 1.10.3.9 GO:0005506 ... P0A444 14764885
    13888 1s5l:d (3.5) BS01 FE 1.10.3.9 GO:0005506 ... Q8CM25 14764885
    13889 1s5m:A (0.98) BS02 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    13890 1s5m:A (0.98) BS03 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    13891 1s5n:A (0.95) BS02 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    13892 1s5n:A (0.95) BS03 MN 5.3.1.5 GO:0000287 ... P15587 15157080
    13893 1s5p:A (1.96) BS02 ZN 2.3.1.286 GO:0036054 ... P75960 15019790
    13894 1s5s:A (1.4) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13895 1s63:B (1.9) BS03 ZN 2.5.1.58 GO:0003824 ... P49356 15248757
    13896 1s64:B (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    13897 1s64:D (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    13898 1s64:F (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    13899 1s64:H (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    13900 1s64:J (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    13901 1s64:L (2.55) BS01 ZN 2.5.1.59 GO:0003824 ... P53610 15248757
    13902 1s6b:A (1.6) BS01 CA 3.1.1.4 GO:0004623 ... P60043 15828003
    13903 1s6b:B (1.6) BS01 CA 3.1.1.4 GO:0004623 ... P60044 15828003
    13904 1s6b:B (1.6) BS02 CA 3.1.1.4 GO:0004623 ... P60044 15828003
    13905 1s6c:A (2.0) BS02 CA ? GO:0005509 ... Q8R426 14980206
    13906 1s6c:A (2.0) BS03 CA ? GO:0005509 ... Q8R426 14980206
    13907 1s6f:A (1.8) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13908 1s6h:A (1.45) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13909 1s6i:A (-1.00) BS01 CA 2.7.11.1 GO:0005509 ... P28583 15155727
    13910 1s6i:A (-1.00) BS02 CA 2.7.11.1 GO:0005509 ... P28583 15155727
    13911 1s6i:A (-1.00) BS03 CA 2.7.11.1 GO:0005509 ... P28583 15155727
    13912 1s6i:A (-1.00) BS04 CA 2.7.11.1 GO:0005509 ... P28583 15155727
    13913 1s6j:A (-1.00) BS01 CA 2.7.11.1 GO:0005509 ... P28583 15568805
    13914 1s6j:A (-1.00) BS02 CA 2.7.11.1 GO:0005509 ... P28583 15568805
    13915 1s6p:A (2.9) BS01 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 15115397
    13916 1s6u:A (-1.00) BS01 CU1 7.2.2.8 GO:0046872 ... Q04656 15035611
    13917 1s70:A (2.7) BS01 MN 3.1.3.16
    3.1.3.53
    GO:0004721 ... P62207 15164081
    13918 1s70:A (2.7) BS02 MN 3.1.3.16
    3.1.3.53
    GO:0004721 ... P62207 15164081
    13919 1s72:3 (2.4) BS02 MG ? GO:0000049 ... P32411 15184028
    13920 1s72:A (2.4) BS02 MG ? GO:0002181 ... P20276 15184028
    13921 1s72:T (2.4) BS02 MG ? GO:0002181 ... P10972 15184028
    13922 1s72:Y (2.4) BS02 MG ? GO:0000166 ... P12736 15184028
    13923 1s76:D (2.88) BS05 MG 2.7.7.6 GO:0000428 ... P00573 15016374
    13924 1s76:D (2.88) BS06 MG 2.7.7.6 GO:0000428 ... P00573 15016374
    13925 1s77:D (2.69) BS04 MG 2.7.7.6 GO:0000428 ... P00573 15016374
    13926 1s7d:A (2.17) BS01 ZN ? GO:0008270 ... P76344 N/A
    13927 1s7d:A (2.17) BS02 ZN ? GO:0008270 ... P76344 N/A
    13928 1s7g:A (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13929 1s7g:A (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13930 1s7g:B (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13931 1s7g:B (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13932 1s7g:C (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13933 1s7g:C (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13934 1s7g:D (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13935 1s7g:D (2.3) BS02 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13936 1s7g:E (2.3) BS01 ZN 2.3.1.286 GO:0005737 ... O30124 15023335
    13937 1s81:A (1.7) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13938 1s82:A (1.85) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13939 1s83:A (1.25) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13940 1s83:A (1.25) BS02 MG 3.4.21.4 GO:0004252 ... P00761 15005618
    13941 1s84:A (1.85) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13942 1s85:A (2.2) BS01 CA 3.4.21.4 GO:0004252 ... P00761 15005618
    13943 1s8e:A (2.3) BS01 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    13944 1s8e:A (2.3) BS02 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    13945 1s8e:B (2.3) BS01 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    13946 1s8e:B (2.3) BS02 MN 3.1.-.- GO:0000729 ... Q8U1N9 15047855
    13947 1s95:A (1.6) BS01 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    13948 1s95:A (1.6) BS02 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    13949 1s95:B (1.6) BS01 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    13950 1s95:B (1.6) BS02 MN 3.1.3.16 GO:0016787 ... P53041 15155720
    13951 1s97:A (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13952 1s97:B (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13953 1s97:C (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13954 1s97:D (2.4) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13955 1s99:A (1.65) BS01 CA ? GO:0030975 ... O34911 15451668
    13956 1s9a:A (2.47) BS01 FE 1.13.11.- GO:0003824 ... O67987 15060064
    13957 1s9a:B (2.47) BS01 FE 1.13.11.- GO:0003824 ... O67987 15060064
    13958 1s9f:A (2.0) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13959 1s9f:A (2.0) BS04 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13960 1s9f:B (2.0) BS04 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13961 1s9f:B (2.0) BS05 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13962 1s9f:C (2.0) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13963 1s9f:C (2.0) BS04 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13964 1s9f:D (2.0) BS03 CA 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13965 1s9f:D (2.0) BS04 MG 2.7.7.7 GO:0000287 ... Q97W02 15077104
    13966 1s9i:A (3.2) BS01 MG 2.7.12.2 GO:0004672 ... P36507 15543157
    13967 1s9i:B (3.2) BS01 MG 2.7.12.2 GO:0004672 ... P36507 15543157
    13968 1s9j:A (2.4) BS01 MG 2.7.12.2 GO:0004672 ... Q02750 15543157
    13969 1sa0:C (3.58) BS01 MG 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    13970 1sa1:A (4.2) BS01 MG 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    13971 1sa1:C (4.2) BS01 MG 3.6.5.- GO:0000226 ... Q2HJ86 15014504
    13972 1sa4:B (2.1) BS03 ZN 2.5.1.58 GO:0003824 ... P49356 15170324
    13973 1sa5:B (2.6) BS01 ZN 2.5.1.58 GO:0003824 ... Q02293 15170324
    13974 1sac:A (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    13975 1sac:A (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    13976 1sac:B (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    13977 1sac:B (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    13978 1sac:C (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    13979 1sac:C (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    13980 1sac:D (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    13981 1sac:D (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    13982 1sac:E (2.0) BS01 CA ? GO:0001849 ... P02743 8114934
    13983 1sac:E (2.0) BS02 CA ? GO:0001849 ... P02743 8114934
    13984 1sat:A (1.75) BS01 ZN 3.4.24.40 GO:0001907 ... P23694 8089845
    13985 1sat:A (1.75) BS02 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    13986 1sat:A (1.75) BS03 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    13987 1sat:A (1.75) BS04 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    13988 1sat:A (1.75) BS05 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    13989 1sat:A (1.75) BS06 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    13990 1sat:A (1.75) BS07 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    13991 1sat:A (1.75) BS08 CA 3.4.24.40 GO:0001907 ... P23694 8089845
    13992 1sav:A (2.5) BS01 CA ? GO:0001786 ... P08758 1311770
    13993 1sav:A (2.5) BS02 CA ? GO:0001786 ... P08758 1311770
    13994 1sav:A (2.5) BS03 CA ? GO:0001786 ... P08758 1311770
    13995 1sav:A (2.5) BS04 CA ? GO:0001786 ... P08758 1311770
    13996 1saw:A (2.2) BS01 MG 3.7.1.5
    4.1.1.112
    GO:0003824 ... Q6P587 15551868
    13997 1saw:A (2.2) BS02 MG 3.7.1.5
    4.1.1.112
    GO:0003824 ... Q6P587 15551868
    13998 1saw:B (2.2) BS01 MG 3.7.1.5
    4.1.1.112
    GO:0003824 ... Q6P587 15551868
    13999 1saw:B (2.2) BS02 MG 3.7.1.5
    4.1.1.112
    GO:0003824 ... Q6P587 15551868
    14000 1sbc:A (2.5) BS01 CA 3.4.21.62 GO:0004252 ... P00780 3150541

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218