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BioLiP
Download all results in tab-seperated text for 197122 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    118801 6bz8:YE (3.74) BS02 MG ? GO:0003735 ... Q5SHN8 30476222
    118802 6bz8:YP (3.74) BS02 MG ? GO:0003735 ... Q5SHQ7 30476222
    118803 6bz8:YP (3.74) BS03 MG ? GO:0003735 ... Q5SHQ7 30476222
    118804 6bz8:YQ (3.74) BS03 MG ? GO:0000049 ... P60489 30476222
    118805 6bz8:YX (3.74) BS02 MG ? GO:0000027 ... Q5SHP0 30476222
    118806 6bz8:YX (3.74) BS03 MG ? GO:0000027 ... Q5SHP0 30476222
    118807 6bz8:YY (3.74) BS02 MG ? GO:0003723 ... Q5SHP9 30476222
    118808 6bz8:YY (3.74) BS03 ZN ? GO:0003723 ... Q5SHP9 30476222
    118809 6bzn:D (1.8) BS01 CA 3.8.1.1 GO:0000166 ... Q4KCZ3 30890712
    118810 6bzo:D (3.38) BS02 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118811 6bzo:D (3.38) BS03 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118812 6bzo:D (3.38) BS04 MG 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118813 6c01:A (2.3) BS02 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118814 6c01:A (2.3) BS03 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118815 6c01:A (2.3) BS04 CA 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118816 6c01:B (2.3) BS02 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118817 6c01:B (2.3) BS03 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118818 6c01:B (2.3) BS04 CA 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118819 6c02:A (1.942) BS02 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118820 6c02:A (1.942) BS03 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118821 6c02:A (1.942) BS04 CA 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118822 6c02:B (1.942) BS01 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118823 6c02:B (1.942) BS02 ZN 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118824 6c02:B (1.942) BS03 CA 3.1.4.1
    3.6.1.9
    GO:0002276 ... O14638 29717535
    118825 6c04:D (3.27) BS02 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118826 6c04:D (3.27) BS03 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118827 6c04:D (3.27) BS04 MG 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118828 6c05:D (5.15) BS01 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118829 6c05:D (5.15) BS02 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118830 6c05:D (5.15) BS03 MG 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118831 6c06:D (5.15) BS01 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118832 6c06:D (5.15) BS02 ZN 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118833 6c06:D (5.15) BS03 MG 2.7.7.6 GO:0000287 ... P9WGY7 29480804
    118834 6c07:A (1.85) BS01 MG 2.5.1.6 GO:0004478 ... Q5CYE4 30950830
    118835 6c07:B (1.85) BS01 MG 2.5.1.6 GO:0004478 ... Q5CYE4 30950830
    118836 6c07:C (1.85) BS01 MG 2.5.1.6 GO:0004478 ... Q5CYE4 30950830
    118837 6c0d:A (1.8) BS01 ZN 3.5.1.87 GO:0016787 ... B2JR29 N/A
    118838 6c0f:j (3.7) BS03 ZN ? GO:0000448 ... P49166 29512650
    118839 6c0f:u (3.7) BS02 ZN ? GO:0001671 ... Q07915 29512650
    118840 6c0j:A (1.92) BS02 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 30044217
    118841 6c0k:A (1.958) BS02 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 30044217
    118842 6c0l:A (1.95) BS02 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 30044217
    118843 6c0m:A (1.83) BS01 CA 3.2.1.18 GO:0004308 ... G8G134 29693380
    118844 6c0m:B (1.83) BS02 CA 3.2.1.18 GO:0004308 ... G8G134 29693380
    118845 6c0n:A (2.001) BS02 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 30044217
    118846 6c0o:A (1.901) BS02 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 30044217
    118847 6c0p:A (2.05) BS02 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 30044217
    118848 6c0r:A (2.049) BS02 MG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16
    GO:0003676 ... P03366 30044217
    118849 6c0v:A (3.4) BS03 MG 7.6.2.1
    7.6.2.2
    GO:0000086 ... P08183 29371429
    118850 6c0v:A (3.4) BS04 MG 7.6.2.1
    7.6.2.2
    GO:0000086 ... P08183 29371429
    118851 6c1g:A (3.8) BS02 MG 3.6.4.- GO:0000287 ... P68135 29358376
    118852 6c1g:B (3.8) BS02 MG 3.6.4.- GO:0000287 ... P68135 29358376
    118853 6c1g:C (3.8) BS02 MG 3.6.4.- GO:0000287 ... P68135 29358376
    118854 6c1j:A (1.063) BS01 MG 5.3.3.1 GO:0004769 ... P07445 29990421
    118855 6c1k:A (2.7) BS01 NA ? GO:0001518 ... A8EVM5 29769724
    118856 6c1k:B (2.7) BS01 NA ? GO:0001518 ... A8EVM5 29769724
    118857 6c1k:B (2.7) BS02 NA ? GO:0001518 ... A8EVM5 29769724
    118858 6c1m:A (2.518) BS05 NA ? GO:0001518 ... A8EVM5 29769724
    118859 6c1m:B (2.518) BS01 NA ? GO:0001518 ... A8EVM5 29769724
    118860 6c1m:B (2.518) BS06 NA ? GO:0001518 ... A8EVM5 29769724
    118861 6c25:A (1.9) BS02 MG 6.3.4.4 GO:0000166 ... Q8RNM2 N/A
    118862 6c2c:A (1.597) BS01 ZN N/A N/A N/A 31636435
    118863 6c2c:A (1.597) BS02 ZN N/A N/A N/A 31636435
    118864 6c2c:B (1.597) BS01 ZN N/A N/A N/A 31636435
    118865 6c2c:B (1.597) BS02 ZN N/A N/A N/A 31636435
    118866 6c2h:A (1.49) BS02 CA 4.2.1.22 GO:0004122 ... P32582 29630349
    118867 6c2m:A (1.859) BS01 ZN 3.6.4.13 GO:0006508 ... C1KIK8 N/A
    118868 6c2m:B (1.859) BS01 ZN 3.6.4.13 GO:0006508 ... C1KIK8 N/A
    118869 6c2m:C (1.859) BS01 ZN 3.6.4.13 GO:0006508 ... C1KIK8 N/A
    118870 6c2m:D (1.859) BS01 ZN 3.6.4.13 GO:0006508 ... C1KIK8 N/A
    118871 6c2n:A (1.802) BS01 ZN 3.4.21.98
    3.6.1.15
    3.6.4.13
    GO:0006508 ... A8DG50 N/A
    118872 6c2o:A (1.179) BS02 ZN 3.6.4.13 GO:0006508 ... C1KIK8 N/A
    118873 6c2q:A (2.17) BS02 CA 4.2.1.22 GO:0004122 ... P32582 29630349
    118874 6c2w:A (4.12) BS01 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118875 6c2w:A (4.12) BS02 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118876 6c2w:A (4.12) BS03 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118877 6c2w:A (4.12) BS04 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118878 6c2w:A (4.12) BS05 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118879 6c2w:A (4.12) BS06 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118880 6c2w:B (4.12) BS01 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118881 6c2w:B (4.12) BS02 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118882 6c2w:B (4.12) BS03 MG 3.4.21.5 GO:0001530 ... P00734 29440720
    118883 6c2x:A (2.6) BS01 MG 2.3.3.9 GO:0000287 ... P9WK17 30137983
    118884 6c2z:A (1.37) BS02 CA 4.2.1.22 GO:0004122 ... P32582 29630349
    118885 6c33:A (1.8) BS01 MN ? GO:0003677 ... I7GAS0 29635474
    118886 6c33:A (1.8) BS02 MN ? GO:0003677 ... I7GAS0 29635474
    118887 6c33:A (1.8) BS03 MN ? GO:0003677 ... I7GAS0 29635474
    118888 6c34:A (2.2) BS01 MN ? GO:0003677 ... I7GAS0 29635474
    118889 6c34:A (2.2) BS02 MN ? GO:0003677 ... I7GAS0 29635474
    118890 6c35:A (1.803) BS01 MN ? GO:0003677 ... I7GAS0 29635474
    118891 6c35:A (1.803) BS02 MN ? GO:0003677 ... I7GAS0 29635474
    118892 6c36:A (1.9) BS01 MN ? GO:0003677 ... I7GAS0 29635474
    118893 6c36:A (1.9) BS02 MN ? GO:0003677 ... I7GAS0 29635474
    118894 6c39:A (1.69) BS01 ZN ? GO:0004180 ... A0A0H2WY27 30366985
    118895 6c3o:E (3.9) BS02 MG ? GO:0001508 ... Q09428 29286281
    118896 6c3o:F (3.9) BS02 MG ? GO:0001508 ... Q09428 29286281
    118897 6c3o:G (3.9) BS02 MG ? GO:0001508 ... Q09428 29286281
    118898 6c3o:H (3.9) BS02 MG ? GO:0001508 ... Q09428 29286281
    118899 6c3p:E (5.6) BS02 MG ? GO:0001508 ... Q09428 29286281
    118900 6c3p:F (5.6) BS02 MG ? GO:0001508 ... Q09428 29286281
    118901 6c3p:G (5.6) BS02 MG ? GO:0001508 ... Q09428 29286281
    118902 6c3p:H (5.6) BS02 MG ? GO:0001508 ... Q09428 29286281
    118903 6c3u:A (1.85) BS01 MN ? GO:0046872 ... A0A0H3GM04 30642934
    118904 6c3u:B (1.85) BS03 MN ? GO:0046872 ... A0A0H3GM04 30642934
    118905 6c3u:C (1.85) BS01 MN ? GO:0046872 ... A0A0H3GM04 30642934
    118906 6c3u:D (1.85) BS01 MN ? GO:0046872 ... A0A0H3GM04 30642934
    118907 6c40:B (2.7) BS01 CU ? GO:0000160 ... Q56312 30222354
    118908 6c40:B (2.7) BS02 CU ? GO:0000160 ... Q56312 30222354
    118909 6c40:D (2.7) BS01 CU ? GO:0000160 ... Q56312 30222354
    118910 6c40:D (2.7) BS02 CU ? GO:0000160 ... Q56312 30222354
    118911 6c46:A (1.95) BS01 CA 5.1.3.13 GO:0005829 ... A0A077ENB9 N/A
    118912 6c46:D (1.95) BS01 CA 5.1.3.13 GO:0005829 ... A0A077ENB9 N/A
    118913 6c49:A (1.85) BS01 ZN 1.1.1.1 GO:0008270 ... A0A1E3MC83 N/A
    118914 6c49:A (1.85) BS02 ZN 1.1.1.1 GO:0008270 ... A0A1E3MC83 N/A
    118915 6c4a:A (1.8) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118916 6c4a:B (1.8) BS03 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118917 6c4a:C (1.8) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118918 6c4a:D (1.8) BS03 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118919 6c4a:E (1.8) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118920 6c4a:F (1.8) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118921 6c4a:G (1.8) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118922 6c4a:H (1.8) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118923 6c4c:A (2.2) BS01 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118924 6c4c:B (2.2) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118925 6c4c:C (2.2) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118926 6c4c:D (2.2) BS01 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118927 6c4c:E (2.2) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118928 6c4c:G (2.2) BS02 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118929 6c4c:H (2.2) BS01 MG 4.1.3.1 GO:0003824 ... P9WKK7 29782144
    118930 6c4i:1 (3.24) BS02 ZN ? GO:0002181 ... P0A7M9 29403017
    118931 6c4i:6 (3.24) BS02 ZN ? GO:0002181 ... P0A7Q6 29403017
    118932 6c4i:C (3.24) BS02 MG ? GO:0000027 ... P60422 29403017
    118933 6c4i:d (3.24) BS02 MG ? GO:0000028 ... P0A7V8 29403017
    118934 6c4p:A (2.3) BS02 CA 4.2.1.22 GO:0004122 ... P32582 29630349
    118935 6c4v:A (1.9) BS01 ZN 2.3.1.- N/A I6X8D2 N/A
    118936 6c55:A (2.09) BS01 MG 1.1.1.86 GO:0000287 ... Q2YUF3 N/A
    118937 6c55:B (2.09) BS05 MG 1.1.1.86 GO:0000287 ... Q2YUF3 N/A
    118938 6c5l:B9 (3.2) BS02 ZN ? GO:0003735 ... Q5SHR2 29403017
    118939 6c5l:BD (3.2) BS02 MG ? GO:0002181 ... P60405 29403017
    118940 6c5l:BF (3.2) BS02 MG ? GO:0003735 ... Q5SHN9 29403017
    118941 6c5l:BP (3.2) BS02 MG ? GO:0003735 ... Q5SHQ7 29403017
    118942 6c5l:CD (3.2) BS02 ZN ? GO:0003723 ... P80373 29403017
    118943 6c5l:CN (3.2) BS02 ZN ? GO:0003735 ... P0DOY6 29403017
    118944 6c5l:D9 (3.2) BS02 ZN ? GO:0003735 ... Q5SHR2 29403017
    118945 6c5l:DD (3.2) BS02 MG ? GO:0002181 ... P60405 29403017
    118946 6c5l:DD (3.2) BS03 MG ? GO:0002181 ... P60405 29403017
    118947 6c5l:DZ (3.2) BS02 MG ? GO:0003723 ... Q5SHZ1 29403017
    118948 6c5n:A (1.673) BS02 MG 1.1.1.86 GO:0000287 ... Q2YUF3 N/A
    118949 6c5n:B (1.673) BS07 MG 1.1.1.86 GO:0000287 ... Q2YUF3 N/A
    118950 6c5u:A (2.41) BS03 MG 2.3.1.-
    2.7.1.190
    N/A P0A0C1 29661878
    118951 6c5u:B (2.41) BS03 MG 2.3.1.-
    2.7.1.190
    N/A P0A0C1 29661878
    118952 6c5u:C (2.41) BS02 MG 2.3.1.-
    2.7.1.190
    N/A P0A0C1 29661878
    118953 6c5u:D (2.41) BS03 MG 2.3.1.-
    2.7.1.190
    N/A P0A0C1 29661878
    118954 6c66:G (3.66) BS02 FE ? GO:0000027 ... Q47PJ0 29880725
    118955 6c66:G (3.66) BS03 FE ? GO:0000027 ... Q47PJ0 29880725
    118956 6c6g:A (2.1) BS01 CA 3.5.1.131 GO:0003824 ... Q936X3 29523689
    118957 6c6g:B (2.1) BS01 CA 3.5.1.131 GO:0003824 ... Q936X3 29523689
    118958 6c6i:A (1.65) BS01 ZN 3.5.2.6 N/A C7C422 30348667
    118959 6c6i:A (1.65) BS02 ZN 3.5.2.6 N/A C7C422 30348667
    118960 6c6i:B (1.65) BS01 ZN 3.5.2.6 N/A C7C422 30348667
    118961 6c6i:B (1.65) BS02 ZN 3.5.2.6 N/A C7C422 30348667
    118962 6c6k:B (2.54) BS02 MG ? GO:0003723 ... P09914 29525521
    118963 6c6o:A (2.3) BS01 MG 2.3.3.9 GO:0000287 ... P9WK17 30137983
    118964 6c6q:A (2.0) BS01 MG ? N/A Q80J94 30194229
    118965 6c6q:A (2.0) BS02 MG ? N/A Q80J94 30194229
    118966 6c6q:B (2.0) BS01 MG ? N/A Q80J94 30194229
    118967 6c6q:B (2.0) BS02 MG ? N/A Q80J94 30194229
    118968 6c6q:D (2.0) BS01 MG ? N/A Q6SJQ7 30194229
    118969 6c6q:F (2.0) BS01 MG ? N/A Q6SJQ7 30194229
    118970 6c6s:J (3.7) BS04 MG 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118971 6c6s:J (3.7) BS05 ZN 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118972 6c6s:J (3.7) BS06 ZN 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118973 6c6t:J (3.5) BS04 MG 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118974 6c6t:J (3.5) BS05 ZN 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118975 6c6t:J (3.5) BS06 ZN 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118976 6c6u:J (3.7) BS04 MG 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118977 6c6u:J (3.7) BS05 ZN 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118978 6c6u:J (3.7) BS06 ZN 2.7.7.6 GO:0000287 ... P0A8T7 29887376
    118979 6c72:A (2.396) BS01 ZN ? N/A A0A0H4TJ34 N/A
    118980 6c72:B (2.396) BS01 ZN ? N/A A0A0H4TJ34 N/A
    118981 6c72:C (2.396) BS01 ZN ? N/A A0A0H4TJ34 N/A
    118982 6c74:A (1.358) BS02 CA ? N/A Q6SJQ7 30194229
    118983 6c75:A (2.4) BS01 FE ? GO:0000166 ... A0A0Q2QQL1 30950821
    118984 6c76:A (2.1) BS01 FE ? GO:0000166 ... A0A0Q2QQL1 30950821
    118985 6c7b:A (2.133) BS02 MG 2.3.3.9 GO:0000287 ... P9WK17 30137983
    118986 6c7d:A (1.79) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118987 6c7d:B (1.79) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118988 6c7d:C (1.79) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118989 6c7d:D (1.79) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118990 6c7e:A (1.43) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118991 6c7e:B (1.43) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118992 6c7e:C (1.43) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118993 6c7e:D (1.43) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118994 6c7f:A (1.82) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118995 6c7f:B (1.82) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118996 6c7f:C (1.82) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118997 6c7g:A (1.68) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118998 6c7g:B (1.68) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    118999 6c7g:C (1.68) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482
    119000 6c7g:D (1.68) BS02 ZN 3.1.4.17 GO:0004114 ... O00408 30070482

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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