Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 30 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3ks9:A (1.9) BS01 Z99 ? GO:0004930 ... Q13255 N/A BindingDB: IC50=7800nM, Ki=6800nM
    2 3ks9:B (1.9) BS01 Z99 ? GO:0004930 ... Q13255 N/A BindingDB: IC50=7800nM, Ki=6800nM
    3 3mq4:A (2.8) BS02 Z99 ? GO:0004930 ... Q14831 N/A BindingDB: IC50=990nM, Ki=990nM
    4 3sm9:A (2.26) BS01 Z99 ? GO:0004930 ... Q14832 N/A BindingDB: Ki=14nM, IC50=10nM
    5 7fd9:A (4.0) BS01 Z99 ? GO:0004930 ... P41594 34469715 BindingDB: Ki=8200nM
    6 7fd9:B (4.0) BS01 Z99 ? GO:0004930 ... P41594 34469715 BindingDB: Ki=8200nM
    7 7mtq:A (3.65) BS01 Z99 ? GO:0004930 ... Q14416 34194039 BindingDB: Ki=3.13nM, IC50=200nM, EC50=>100000nM
    8 7mtq:B (3.65) BS01 Z99 ? GO:0004930 ... Q14416 34194039 BindingDB: Ki=3.13nM, IC50=200nM, EC50=>100000nM
    9 7wi6:A (3.71) BS01 Z99 ? GO:0001641 ... Q14832 35236939
    10 7wi6:B (3.71) BS01 Z99 ? GO:0001641 ... Q14832 35236939
    11 7wi8:A (4.17) BS01 Z99 ? GO:0001641 ... Q14832 35236939
    12 7wi8:B (4.17) BS01 Z99 ? GO:0001641 ... Q14832 35236939
    13 8jcu:2 (2.8) BS01 Z99 5.2.1.8 GO:0000413 ... P62942
    Q14416    		 37286794
    14 8jcu:3 (2.8) BS01 Z99 2.7.11.1 GO:0001641 ... A0A8V8TRG9
    Q14832    		 37286794
    15 8jcv:2 (3.4) BS01 Z99 5.2.1.8 GO:0001641 ... P62942
    Q14416    		 37286794
    16 8jcv:3 (3.4) BS01 Z99 2.7.11.1 GO:0001641 ... A0A8V8TRG9
    Q14832    		 37286794
    17 8jcw:2 (3.0) BS01 Z99 5.2.1.8 GO:0000413 ... P62942
    Q14416    		 37286794
    18 8jcw:3 (3.0) BS01 Z99 2.7.11.1 GO:0001641 ... A0A8V8TRG9
    Q14832    		 37286794
    19 8jcx:2 (3.0) BS01 Z99 5.2.1.8 GO:0000413 ... P62942
    Q14416    		 37286794
    20 8jcx:3 (3.0) BS01 Z99 2.7.11.1 GO:0001641 ... A0A8V8TRG9
    Q14832    		 37286794
    21 8jcy:2 (2.9) BS01 Z99 5.2.1.8 GO:0000413 ... P62942
    Q14416    		 37286794
    22 8jcy:3 (2.9) BS01 Z99 2.7.11.1 GO:0001641 ... A0A8V8TRG9
    Q14832    		 37286794
    23 8jcz:2 (3.0) BS01 Z99 5.2.1.8 GO:0000413 ... P62942
    Q14416    		 37286794
    24 8jcz:3 (3.0) BS01 Z99 2.7.11.1 GO:0001641 ... A0A8V8TRG9
    Q14832    		 37286794
    25 8tr0:A (3.2) BS01 Z99 N/A N/A P31422 37645747
    26 8tr0:B (3.2) BS01 Z99 N/A N/A P31422 37645747
    27 8trc:A (3.3) BS01 Z99 N/A N/A P31422 37645747
    28 8trc:B (3.3) BS01 Z99 N/A N/A P31422 37645747
    29 8trd:A (3.4) BS01 Z99 N/A N/A P31422 39090128
    30 8trd:B (3.4) BS01 Z99 N/A N/A P31422 39090128
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218