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BioLiP
Download all results in tab-seperated text for 18 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3clx:A (2.7) BS01 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    2 3clx:A (2.7) BS03 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    3 3clx:B (2.7) BS02 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    4 3clx:C (2.7) BS02 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    5 3clx:C (2.7) BS03 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    6 3clx:C (2.7) BS04 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    7 3clx:D (2.7) BS02 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    8 3clx:D (2.7) BS03 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    9 3clx:D (2.7) BS04 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    10 3clx:D (2.7) BS05 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    11 3cm7:A (3.1) BS02 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    12 3cm7:B (3.1) BS02 X22 2.3.2.27 N/A P98170 18851976 PDBbind: -logKd/Ki=6.57, IC50=270nM
    BindingDB: IC50=290nM
    13 3cm7:C (3.1) BS02 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    14 3cm7:C (3.1) BS03 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    15 3cm7:C (3.1) BS04 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    16 3cm7:D (3.1) BS02 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    17 3cm7:D (3.1) BS03 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    18 3cm7:D (3.1) BS04 X22 2.3.2.27 N/A P98170 18851976 BindingDB: IC50=290nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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