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BioLiP
Download all results in tab-seperated text for 295 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1cr4:A (2.5) BS01 TYD 2.7.7.-
    3.6.4.12
    GO:0003678 ... P03692 10535735
    2 1e2g:A (1.7) BS03 TYD 2.7.4.9 GO:0004550 ... P23919 10873853
    3 1epz:A (1.75) BS01 TYD 5.1.3.13 GO:0005829 ... O27818 10827167
    4 1gtv:A (1.55) BS02 TYD 2.7.4.9 GO:0000287 ... P9WKE1 11914484
    5 1gtv:B (1.55) BS02 TYD 2.7.4.9 GO:0000287 ... P9WKE1 11914484
    6 1h5t:A (1.9) BS01 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    7 1h5t:A (1.9) BS03 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    8 1h5t:B (1.9) BS01 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    9 1h5t:B (1.9) BS03 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    10 1h5t:C (1.9) BS01 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    11 1h5t:C (1.9) BS02 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    12 1h5t:D (1.9) BS01 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    13 1h5t:D (1.9) BS02 TYD 2.7.7.24 GO:0005829 ... P37744 11697907
    14 1h7l:A (1.98) BS01 TYD ? GO:0016757 ... P39621 11733986
    15 1h7q:A (2.0) BS01 TYD ? GO:0016757 ... P39621 11733986
    16 1ket:A (1.8) BS01 TYD 4.2.1.46 GO:0008460 ... P95780 11796113
    17 1ket:B (1.8) BS01 TYD 4.2.1.46 GO:0008460 ... P95780 11796113
    18 1kew:A (1.8) BS01 TYD 4.2.1.46 GO:0008460 ... P26391 11796113
    19 1kew:B (1.8) BS01 TYD 4.2.1.46 GO:0008460 ... P26391 11796113
    20 1lvw:A (1.7) BS01 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    21 1lvw:A (1.7) BS02 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    22 1lvw:B (1.7) BS01 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    23 1lvw:B (1.7) BS02 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    24 1lvw:C (1.7) BS01 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    25 1lvw:C (1.7) BS02 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    26 1lvw:D (1.7) BS01 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    27 1lvw:D (1.7) BS02 TYD 2.7.7.24 GO:0008879 ... O27819 N/A
    28 1n5j:A (1.85) BS02 TYD 2.7.4.9 GO:0000287 ... P9WKE1 12662932
    29 1n5l:B (2.3) BS01 TYD 2.7.4.9 GO:0000287 ... P9WKE1 12662932
    30 1ndc:A (2.0) BS01 TYD 2.7.4.6 GO:0004550 ... P22887 8049207
    31 1pn3:A (2.8) BS02 TYD 2.4.1.311 GO:0005975 ... P96558 12874381
    32 1pnv:A (2.8) BS01 TYD 2.4.1.311 GO:0005975 ... P96558 12874381
    33 1r66:A (1.44) BS02 TYD 4.2.1.46 GO:0000166 ... Q9ZGH3 14570895
    34 1rrv:A (2.0) BS02 TYD 2.4.1.322 GO:0005975 ... Q9AFC7 15122882
    35 1rrv:B (2.0) BS02 TYD 2.4.1.322 GO:0005975 ... Q9AFC7 15122882
    36 2b8q:A (2.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    37 2b8q:B (2.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    38 2b8q:C (2.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    39 2b8q:D (2.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    40 2b8q:E (2.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    41 2b8q:F (2.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    42 2ixi:A (1.8) BS01 TYD 5.1.3.13 GO:0005829 ... Q9HU21 17046787 MOAD: Ka=1320M^-1
    43 2ixi:B (1.8) BS01 TYD 5.1.3.13 GO:0005829 ... Q9HU21 17046787 MOAD: Ka=1320M^-1
    44 2ixi:B (1.8) BS02 TYD 5.1.3.13 GO:0005829 ... Q9HU21 17046787 MOAD: Ka=1320M^-1
    45 2j4q:A (2.6) BS01 TYD 3.5.4.13 GO:0000166 ... P28248 17651436
    46 2pa7:A (1.5) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    47 2pa7:A (1.5) BS02 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    48 2pa7:B (1.5) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    49 2pa7:B (1.5) BS02 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    50 2pae:A (2.5) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    51 2pae:B (2.5) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    52 2pae:B (2.5) BS02 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    53 2pak:A (2.4) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    54 2pak:A (2.4) BS02 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    55 2pak:B (2.4) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    56 2pak:B (2.4) BS02 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    57 2pam:A (2.5) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    58 2pam:B (2.5) BS01 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    59 2pam:B (2.5) BS02 TYD 5.3.2.3 GO:0016853 ... Q6T1W8 17459872
    60 2v54:A (2.4) BS01 TYD 2.7.4.9 GO:0004550 ... P68693 18971333 PDBbind: -logKd/Ki=4.60, Ki=25uM
    61 2v54:B (2.4) BS03 TYD 2.7.4.9 GO:0004550 ... P68693 18971333
    62 2x0e:A (2.81) BS01 TYD ? GO:0030247 ... Q7BG50 20097205
    63 2x0e:B (2.81) BS01 TYD ? GO:0030247 ... Q7BG50 20097205
    64 3ddi:A (1.9) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    65 3ddi:B (1.9) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    66 3em1:A (1.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    67 3em1:B (1.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    68 3evo:A (1.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    69 3evo:B (1.5) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    70 3evw:A (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    71 3evw:B (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    72 3evw:C (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    73 3evw:D (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    74 3evw:E (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    75 3evw:F (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    76 3fbc:A (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    77 3fbc:B (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    78 3fbc:C (2.6) BS02 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    79 3fbc:D (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    80 3fbc:E (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    81 3fbc:F (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    82 3fbf:A (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    83 3fbf:B (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    84 3fbf:C (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    85 3fbf:D (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    86 3fbf:E (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    87 3fbf:F (2.6) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    88 3g2x:A (2.7) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    89 3g2x:B (2.7) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    90 3g2x:C (2.7) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    91 3g2x:D (2.7) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    92 3g2x:E (2.7) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    93 3g2x:F (2.7) BS01 TYD 2.7.4.6 GO:0004550 ... Q5UQL3 19439473
    94 3hjn:A (2.1) BS02 TYD 2.7.4.9 GO:0004798 ... Q9X0I3 N/A
    95 3hjn:B (2.1) BS02 TYD 2.7.4.9 GO:0004798 ... Q9X0I3 N/A
    96 3iaa:A (2.505) BS01 TYD ? GO:0008194 ... Q8KNE0 21987796
    97 3iaa:B (2.505) BS01 TYD ? GO:0008194 ... Q8KNE0 21987796
    98 3lv8:A (1.8) BS03 TYD 2.7.4.9 GO:0004712 ... Q9KQI2 N/A
    99 3m9v:A (2.05) BS01 TYD ? GO:0000166 ... B3TMR1 20334431
    100 3otg:A (2.08) BS01 TYD ? GO:0008194 ... Q8KNF2 21987796
    101 3oth:A (2.301) BS01 TYD ? GO:0008194 ... Q8KNF2 21987796
    102 3oth:B (2.301) BS01 TYD ? GO:0008194 ... Q8KNF2 21987796
    103 3oti:A (1.597) BS01 TYD ? GO:0008194 ... Q8KND7 21987796
    104 3oti:B (1.597) BS01 TYD ? GO:0008194 ... Q8KND7 21987796
    105 3rsc:A (2.19) BS01 TYD ? GO:0008194 ... Q8KNE0 21987796
    106 3rsc:B (2.19) BS01 TYD ? GO:0008194 ... Q8KNE0 21987796
    107 3ryk:A (1.631) BS02 TYD 5.1.3.13 GO:0005829 ... A0A6L7H6N0 29199987
    108 3ryk:B (1.631) BS01 TYD 5.1.3.13 GO:0005829 ... A0A6L7H6N0 29199987
    109 3uyl:A (1.85) BS01 TYD 2.4.1.- GO:0008194 ... Q9ALM8 22283226
    110 3uyl:B (1.85) BS01 TYD 2.4.1.- GO:0008194 ... Q9ALM8 22283226
    111 3vbj:A (1.8) BS01 TYD N/A GO:0016740 ... N/A 22220494
    112 3vbj:A (1.8) BS03 TYD N/A GO:0016740 ... N/A 22220494
    113 3vbj:C (1.8) BS01 TYD N/A GO:0016740 ... N/A 22220494
    114 3vbj:C (1.8) BS03 TYD N/A GO:0016740 ... N/A 22220494
    115 3vbj:E (1.8) BS01 TYD N/A GO:0016740 ... N/A 22220494
    116 3vbj:E (1.8) BS03 TYD N/A GO:0016740 ... N/A 22220494
    117 3vbm:A (1.9) BS03 TYD N/A GO:0016740 ... N/A 22220494
    118 3vbm:A (1.9) BS04 TYD N/A GO:0016740 ... N/A 22220494
    119 3vbm:C (1.9) BS02 TYD N/A GO:0016740 ... N/A 22220494
    120 3vbm:C (1.9) BS04 TYD N/A GO:0016740 ... N/A 22220494
    121 3vbm:E (1.9) BS03 TYD N/A GO:0016740 ... N/A 22220494
    122 3vbm:E (1.9) BS04 TYD N/A GO:0016740 ... N/A 22220494
    123 3vbn:A (2.5) BS02 TYD N/A GO:0016740 ... N/A 22220494
    124 3vbn:A (2.5) BS04 TYD N/A GO:0016740 ... N/A 22220494
    125 3vbn:C (2.5) BS01 TYD N/A GO:0016740 ... N/A 22220494
    126 3vbn:C (2.5) BS03 TYD N/A GO:0016740 ... N/A 22220494
    127 3vbn:E (2.5) BS02 TYD N/A GO:0016740 ... N/A 22220494
    128 3vbn:E (2.5) BS04 TYD N/A GO:0016740 ... N/A 22220494
    129 3vbp:A (2.3) BS02 TYD N/A GO:0016740 ... N/A 22220494
    130 3vbp:A (2.3) BS04 TYD N/A GO:0016740 ... N/A 22220494
    131 3vbp:C (2.3) BS01 TYD N/A GO:0016740 ... N/A 22220494
    132 3vbp:C (2.3) BS03 TYD N/A GO:0016740 ... N/A 22220494
    133 3vbp:E (2.3) BS02 TYD N/A GO:0016740 ... N/A 22220494
    134 3vbp:E (2.3) BS04 TYD N/A GO:0016740 ... N/A 22220494
    135 3wag:A (2.1) BS01 TYD ? GO:0008194 ... Q76KZ6 N/A
    136 3wag:B (2.1) BS01 TYD ? GO:0008194 ... Q76KZ6 N/A
    137 4e2x:A (1.4) BS03 TYD 2.1.1.- GO:0008168 ... B5L6K6 22495991
    138 4e30:A (1.5) BS02 TYD 2.1.1.- GO:0008168 ... B5L6K6 22495991
    139 4g2t:A (2.405) BS01 TYD ? GO:0008194 ... D6MSX4 23526584
    140 4hn1:A (1.6) BS01 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    141 4hn1:A (1.6) BS02 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    142 4hn1:B (1.6) BS01 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    143 4hn1:B (1.6) BS02 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    144 4hn1:C (1.6) BS01 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    145 4hn1:C (1.6) BS02 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    146 4hn1:D (1.6) BS01 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    147 4hn1:D (1.6) BS02 TYD 5.1.3.27 GO:0005829 ... Q5SFD1 23116432
    148 4lei:A (3.15) BS01 TYD ? GO:0008194 ... Q9ALN7 24945604
    149 4lei:B (3.15) BS01 TYD ? GO:0008194 ... Q9ALN7 24945604
    150 4lxq:A (1.4) BS02 TYD N/A GO:0009058 ... N/A 23898784
    151 4lxq:B (1.4) BS02 TYD N/A GO:0009058 ... N/A 23898784
    152 4lxy:A (1.64) BS02 TYD N/A GO:0009058 ... N/A 23898784
    153 4lxy:B (1.64) BS02 TYD N/A GO:0009058 ... N/A 23898784
    154 4mzu:A (2.2) BS02 TYD ? GO:0016740 ... Q12KT8 24128043
    155 4mzu:B (2.2) BS02 TYD ? GO:0016740 ... Q12KT8 24128043
    156 4mzu:B (2.2) BS06 TYD ? GO:0016740 ... Q12KT8 24128043
    157 4mzu:C (2.2) BS03 TYD ? GO:0016740 ... Q12KT8 24128043
    158 4mzu:C (2.2) BS05 TYD ? GO:0016740 ... Q12KT8 24128043
    159 4mzu:D (2.2) BS01 TYD ? GO:0016740 ... Q12KT8 24128043
    160 4mzu:D (2.2) BS03 TYD ? GO:0016740 ... Q12KT8 24128043
    161 4mzu:E (2.2) BS01 TYD ? GO:0016740 ... Q12KT8 24128043
    162 4mzu:E (2.2) BS03 TYD ? GO:0016740 ... Q12KT8 24128043
    163 4mzu:F (2.2) BS03 TYD ? GO:0016740 ... Q12KT8 24128043
    164 4mzu:G (2.2) BS02 TYD ? GO:0016740 ... Q12KT8 24128043
    165 4mzu:H (2.2) BS02 TYD ? GO:0016740 ... Q12KT8 24128043
    166 4mzu:H (2.2) BS04 TYD ? GO:0016740 ... Q12KT8 24128043
    167 4mzu:I (2.2) BS03 TYD ? GO:0016740 ... Q12KT8 24128043
    168 4mzu:I (2.2) BS04 TYD ? GO:0016740 ... Q12KT8 24128043
    169 4mzu:J (2.2) BS02 TYD ? GO:0016740 ... Q12KT8 24128043
    170 4mzu:K (2.2) BS01 TYD ? GO:0016740 ... Q12KT8 24128043
    171 4mzu:K (2.2) BS03 TYD ? GO:0016740 ... Q12KT8 24128043
    172 4mzu:L (2.2) BS03 TYD ? GO:0016740 ... Q12KT8 24128043
    173 4nv1:D (2.1) BS01 TYD ? GO:0004479 ... Q5NF01 24347283
    174 4nv1:F (2.1) BS01 TYD ? GO:0004479 ... Q5NF01 24347283
    175 4nv1:H (2.1) BS01 TYD ? GO:0004479 ... Q5NF01 24347283
    176 4o7s:A (2.24) BS01 TYD 6.3.2.6 GO:0004639 ... O57978 N/A
    177 4o7w:A (2.2) BS01 TYD 6.3.2.6 GO:0004639 ... O57978 N/A
    178 4o9e:A (2.0) BS01 TYD ? N/A Q6TFC5 24616215
    179 4o9e:A (2.0) BS03 TYD ? N/A Q6TFC5 24616215
    180 4o9e:B (2.0) BS01 TYD ? N/A Q6TFC5 24616215
    181 4o9e:B (2.0) BS02 TYD ? N/A Q6TFC5 24616215
    182 4rii:A (2.0) BS01 TYD ? GO:0008194 ... Q9RPA7
    Q9ZGC0
    25581707
    183 4rii:B (2.0) BS01 TYD ? GO:0008194 ... Q9RPA7
    Q9ZGC0
    25581707
    184 4rvf:A (2.7) BS02 TYD ? GO:0008168 ... Q194Q4 25587924
    185 4rvg:A (2.3) BS02 TYD ? GO:0008168 ... Q194Q4 25587924
    186 4zas:D (2.47) BS01 TYD ? GO:0000271 ... Q8KND8 N/A
    187 4zas:E (2.47) BS01 TYD ? GO:0000271 ... Q8KND8 N/A
    188 4zas:F (2.47) BS01 TYD ? GO:0000271 ... Q8KND8 N/A
    189 4zu7:A (2.3) BS01 TYD ? N/A Q6TFC5 26125548
    190 4zu7:A (2.3) BS02 TYD ? N/A Q6TFC5 26125548
    191 4zu7:B (2.3) BS01 TYD ? N/A Q6TFC5 26125548
    192 4zu7:B (2.3) BS02 TYD ? N/A Q6TFC5 26125548
    193 4zu7:C (2.3) BS01 TYD ? N/A Q6TFC5 26125548
    194 4zu7:C (2.3) BS02 TYD ? N/A Q6TFC5 26125548
    195 4zu7:D (2.3) BS01 TYD ? N/A Q6TFC5 26125548
    196 4zu7:D (2.3) BS02 TYD ? N/A Q6TFC5 26125548
    197 4zu7:E (2.3) BS01 TYD ? N/A Q6TFC5 26125548
    198 4zu7:E (2.3) BS02 TYD ? N/A Q6TFC5 26125548
    199 4zu7:F (2.3) BS01 TYD ? N/A Q6TFC5 26125548
    200 4zu7:F (2.3) BS02 TYD ? N/A Q6TFC5 26125548

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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