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BioLiP
Download all results in tab-seperated text for 28 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1ea1:A (2.21) BS02 TPF 1.14.15.36 GO:0004497 ... P9WPP9 11248033
    2 2ij7:A (1.9) BS02 TPF 1.14.19.70 GO:0004497 ... P9WPP7 17028183 MOAD: Kd=5uM
    BindingDB: Kd=6000nM
    3 2ij7:B (1.9) BS02 TPF 1.14.19.70 GO:0004497 ... P9WPP7 17028183 MOAD: Kd=5uM
    BindingDB: Kd=6000nM
    4 2ij7:C (1.9) BS02 TPF 1.14.19.70 GO:0004497 ... P9WPP7 17028183 MOAD: Kd=5uM
    BindingDB: Kd=6000nM
    5 2ij7:D (1.9) BS02 TPF 1.14.19.70 GO:0004497 ... P9WPP7 17028183 MOAD: Kd=5uM
    BindingDB: Kd=6000nM
    6 2ij7:F (1.9) BS02 TPF 1.14.19.70 GO:0004497 ... P9WPP7 17028183 MOAD: Kd=5uM
    BindingDB: Kd=6000nM
    7 2wuz:A (2.35) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    8 2wuz:B (2.35) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    9 2wv2:A (2.7) BS01 TPF 1.14.13.70 GO:0004497 ... Q385E8 20386598 BindingDB: Kd=3.4e+2nM
    10 2wx2:A (2.27) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    11 2wx2:B (2.27) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20386598 BindingDB: IC50=880nM, Kd=2.3e+2nM
    12 3khm:A (2.85) BS02 TPF 1.14.14.154 GO:0004497 ... Q7Z1V1 20530488 BindingDB: IC50=880nM, Kd=2.3e+2nM
    13 3l4d:A (2.75) BS02 TPF 1.14.13.70 GO:0004497 ... A2TEF2 21632531
    14 3l4d:B (2.75) BS02 TPF 1.14.13.70 GO:0004497 ... A2TEF2 21632531
    15 3l4d:C (2.75) BS02 TPF 1.14.13.70 GO:0004497 ... A2TEF2 21632531
    16 3l4d:D (2.75) BS02 TPF 1.14.13.70 GO:0004497 ... A2TEF2 21632531
    17 4wmz:A (2.05) BS02 TPF ? GO:0004497 ... A6ZSR0 26055382 MOAD: Kd=0.074uM
    18 4zdz:A (2.3) BS02 TPF ? GO:0004497 ... A6ZSR0 27188873 MOAD: Kd=0.13uM
    19 4ze3:A (2.2) BS02 TPF ? GO:0004497 ... A6ZSR0 27188873 MOAD: Kd=0.11uM
    20 5ese:A (2.2) BS02 TPF 1.14.13.70 GO:0004497 ... A6ZSR0 29263059
    21 5esf:A (2.25) BS02 TPF 1.14.13.70 GO:0004497 ... A6ZSR0 29263059
    22 5esj:A (2.15) BS02 TPF ? GO:0004497 ... A6ZSR0 29263059
    23 5esm:A (2.0) BS02 TPF 1.14.13.70 GO:0004497 ... A6ZSR0 N/A
    24 6ay4:A (2.7) BS02 TPF ? GO:0004497 ... A0A2H4A2U9 29284029
    25 6h1s:A (1.95) BS01 TPF 1.14.14.1
    1.6.2.4    		 GO:0004497 ... P14779 30733479
    26 6h1s:B (1.95) BS01 TPF 1.14.14.1
    1.6.2.4    		 GO:0004497 ... P14779 30733479
    27 6ma7:A (2.09) BS02 TPF 1.14.14.1
    1.14.14.55
    1.14.14.56
    1.14.14.73    		 GO:0002933 ... P08684 30676743 MOAD: Kd=17uM
    BindingDB: IC50=8000nM
    28 9iul:A (3.3) BS02 TPF N/A N/A Q5ANA3 39242571
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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