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BioLiP
Download all results in tab-seperated text for 8 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 3hku:A (1.8) BS02 TOR 4.2.1.1
    4.2.1.69    		 GO:0002009 ... P00918 19827837 PDBbind: -logKd/Ki=8.30, Ki=5nM
    BindingDB: Ki=10nM, Kd=290nM, IC50=5nM
    2 3lxe:A (1.9) BS02 TOR 4.2.1.1
    4.2.1.69    		 GO:0004064 ... P00915 20505865 MOAD: Ki=250nM
    PDBbind: -logKd/Ki=6.60, Ki=250nM
    BindingDB: Ki=250nM, IC50=250nM
    3 3lxe:B (1.9) BS02 TOR 4.2.1.1
    4.2.1.69    		 GO:0004064 ... P00915 20505865 MOAD: Ki=250nM
    BindingDB: Ki=250nM, IC50=250nM
    4 5jna:A (2.0) BS02 TOR 4.2.1.1 GO:0004089 ... P22748 28975383 PDBbind: -logKd/Ki=7.35, Kd=45nM
    BindingDB: Ki=4900nM
    5 5jna:B (2.0) BS02 TOR 4.2.1.1 GO:0004089 ... P22748 28975383 BindingDB: Ki=4900nM
    6 5jna:C (2.0) BS02 TOR 4.2.1.1 GO:0004089 ... P22748 28975383 BindingDB: Ki=4900nM
    7 5jna:D (2.0) BS02 TOR 4.2.1.1 GO:0004089 ... P22748 28975383 BindingDB: Ki=4900nM
    8 7yg5:A (3.0) BS10 TOR ? GO:0005216 ... Q15878 38901222
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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