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BioLiP
Download all results in tab-seperated text for 8 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1ah3:A (2.3) BS02 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P80276 9195881 BindingDB: IC50=16nM
    2 1zua:X (1.25) BS02 TOL 1.1.1.300
    1.1.1.54    		 GO:0001523 ... O60218 18087047 MOAD: ic50=10nM
    BindingDB: IC50=54nM, Ki=50nM
    3 2fzb:A (1.5) BS02 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 16952371 BindingDB: IC50=10.0nM
    4 2fzb:A (1.5) BS03 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 16952371 BindingDB: IC50=10.0nM
    5 2fzb:A (1.5) BS04 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 16952371 BindingDB: IC50=10.0nM
    6 2fzd:A (1.08) BS02 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 16952371 BindingDB: IC50=10.0nM
    7 2pdl:A (1.47) BS02 TOL 1.1.1.21
    1.1.1.300
    1.1.1.372
    1.1.1.54    		 GO:0001523 ... P15121 18495158 MOAD: Kd=588nM
    BindingDB: IC50=10.0nM
    8 6kik:A (1.601) BS01 TOL ? GO:0000166 ... Q9X265 31573681
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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