Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 15 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1acj:A (2.8) BS01 THA 3.1.1.7 GO:0001507 ... P04058 8415649 PDBbind: -logKd/Ki=8.09, IC50=8.2nM
    BindingDB: IC50=29nM, Ki=40nM
    2 1mx1:A (2.4) BS02 THA 3.1.1.1
    3.1.1.13
    3.1.1.56    		 GO:0004771 ... P23141 12725862 PDBbind: -logKd/Ki=4.00, Ki>100uM
    BindingDB: IC50=>100000nM, Ki=>100000nM
    3 1mx1:B (2.4) BS03 THA 3.1.1.1
    3.1.1.13
    3.1.1.56    		 GO:0004771 ... P23141 12725862 BindingDB: IC50=>100000nM, Ki=>100000nM
    4 1mx1:C (2.4) BS01 THA 3.1.1.1
    3.1.1.13
    3.1.1.56    		 GO:0004771 ... P23141 12725862 BindingDB: IC50=>100000nM, Ki=>100000nM
    5 1mx1:D (2.4) BS02 THA 3.1.1.1
    3.1.1.13
    3.1.1.56    		 GO:0004771 ... P23141 12725862 BindingDB: IC50=>100000nM, Ki=>100000nM
    6 1mx1:E (2.4) BS02 THA 3.1.1.1
    3.1.1.13
    3.1.1.56    		 GO:0004771 ... P23141 12725862 BindingDB: IC50=>100000nM, Ki=>100000nM
    7 1mx1:F (2.4) BS01 THA 3.1.1.1
    3.1.1.13
    3.1.1.56    		 GO:0004771 ... P23141 12725862 BindingDB: IC50=>100000nM, Ki=>100000nM
    8 2aow:A (2.97) BS01 THA 2.1.1.8 GO:0001692 ... P50135 16168438 PDBbind: -logKd/Ki=7.42, Ki=38.2nM
    9 2aow:B (2.97) BS01 THA 2.1.1.8 GO:0001692 ... P50135 16168438
    10 2aox:A (3.12) BS01 THA 2.1.1.8 GO:0001692 ... P50135 16168438 PDBbind: -logKd/Ki=7.42, Ki=38.2nM
    11 2aox:B (3.12) BS01 THA 2.1.1.8 GO:0001692 ... P50135 16168438
    12 4bds:A (2.1) BS03 THA 3.1.1.8 GO:0001540 ... P06276 23679855 MOAD: Ki=25nM
    PDBbind: -logKd/Ki=7.60, Ki=25nM
    BindingDB: IC50=23nM, Ki=7nM
    13 7xn1:A (2.85) BS01 THA 3.1.1.7 GO:0001507 ... P22303 N/A
    14 7xn1:B (2.85) BS01 THA 3.1.1.7 GO:0001507 ... P22303 N/A
    15 8t5g:A (1.92) BS01 THA ? GO:0005085 ... Q07890 38156904
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218