Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 55 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1afs:A (2.5) BS02 TES 1.1.1.50 GO:0004032 ... P23457 9261071
    2 1afs:B (2.5) BS02 TES 1.1.1.50 GO:0004032 ... P23457 9261071
    3 1i9j:H (2.6) BS01 TES ? N/A Q91Z05 11707437
    4 1j96:A (1.25) BS02 TES 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20    		 GO:0004032 ... P52895 11514561
    5 1j96:B (1.25) BS02 TES 1.-.-.-
    1.1.1.112
    1.1.1.209
    1.1.1.357
    1.1.1.53
    1.1.1.62
    1.3.1.20    		 GO:0004032 ... P52895 11514561
    6 1jtv:A (1.54) BS01 TES 1.1.1.51
    1.1.1.62    		 GO:0003824 ... P14061 12490543
    7 1q13:A (2.08) BS02 TES 1.1.1.149
    1.1.1.189    		 GO:0001516 ... P80508 15123423
    8 1vpo:H (2.15) BS01 TES N/A N/A N/A 12196551 MOAD: Kd=0.000000064M
    9 1vpo:L (2.15) BS01 TES N/A N/A N/A 12196551
    10 2am9:A (1.64) BS01 TES ? N/A P10275 16641486 PDBbind: -logKd/Ki=8.41, IC50=3.9nM
    BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    11 2q7i:A (1.87) BS02 TES ? N/A P10275 17591767 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    12 2q7j:A (1.9) BS02 TES ? N/A P10275 17591767 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    13 2q7k:A (1.8) BS02 TES ? N/A P10275 17591767 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    14 2q7l:A (1.92) BS02 TES ? N/A P10275 17591767 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    15 2yhd:A (2.2) BS01 TES ? N/A P10275 21846139 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    16 2ylo:A (2.5) BS01 TES ? N/A P10275 22047606 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    17 2ylp:A (2.3) BS01 TES ? N/A P10275 22047606 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    18 2ylq:A (2.4) BS01 TES ? N/A P10275 22047606 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    19 3bur:A (1.62) BS02 TES 1.3.1.3 GO:0004032 ... P51857 18407998 MOAD: Ki=14.45uM
    20 3bur:B (1.62) BS02 TES 1.3.1.3 GO:0004032 ... P51857 18407998 MOAD: Ki=14.45uM
    21 3kdm:B (1.5) BS01 TES N/A N/A N/A 21360611 MOAD: Kd=0.1uM
    22 3kdm:H (1.5) BS01 TES N/A N/A N/A 21360611 MOAD: Kd=0.1uM
    PDBbind: -logKd/Ki=7.00, Kd=0.1uM
    23 3kdm:L (1.5) BS01 TES N/A N/A N/A 21360611 PDBbind: -logKd/Ki=7.00, Kd=0.1uM
    24 3uzz:A (1.82) BS02 TES 1.3.1.3 GO:0004032 ... P51857 22437839
    25 3zqt:A (2.29) BS01 TES ? N/A P10275 22047606 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    26 4hlw:A (2.5) BS01 TES ? N/A P10275 23301637 BindingDB: IC50=2.7nM, Ki=3.2nM, EC50=1.1nM
    27 4j6d:A (2.4) BS03 TES ? GO:0004497 ... Q5YNS8 25372679
    28 4j6d:B (2.4) BS02 TES ? GO:0004497 ... Q5YNS8 25372679
    29 5jkw:A (3.0) BS02 TES 1.14.14.14 GO:0002677 ... P11511 29476820 BindingDB: Ki=600nM
    30 5og9:B (2.09) BS03 TES 1.14.14.1
    1.6.2.4    		 GO:0004497 ... P14779 N/A
    31 5og9:B (2.09) BS04 TES 1.14.14.1
    1.6.2.4    		 GO:0004497 ... P14779 N/A
    32 6a7j:A (2.71) BS02 TES ? GO:0004497 ... A0A1V0UEC8 30552795
    33 6hgl:A (1.92) BS01 TES ? GO:0003677 ... P01011 31103428
    34 6hgl:B (1.92) BS01 TES ? N/A P01011 31103428
    35 6ly4:A (1.68) BS01 TES 1.14.14.1
    1.6.2.4    		 GO:0004497 ... P14779 32243054
    36 6mdq:A (2.15) BS01 TES ? GO:0003677 ... P35747 30842823 PDBbind: -logKd/Ki=3.44, Kd=367uM
    37 6mdq:A (2.15) BS02 TES ? GO:0003677 ... P35747 30842823 PDBbind: -logKd/Ki=3.44, Kd=367uM
    38 7cl8:A (1.42) BS02 TES ? GO:0004497 ... Q82GL5 36847541
    39 7y98:A (2.27) BS02 TES ? GO:0004497 ... M5PFT9 N/A
    40 7y98:B (2.27) BS02 TES ? GO:0004497 ... M5PFT9 N/A
    41 8abs:A (1.75) BS03 TES 1.14.-.- GO:0004497 ... D5DF88 37453052
    42 8fw3:A (2.22) BS01 TES ? GO:0003677 ... P39897 38326294
    43 8fw3:B (2.22) BS01 TES ? GO:0003677 ... P39897 38326294
    44 8fw3:C (2.22) BS01 TES ? GO:0003677 ... P39897 38326294
    45 8fw3:D (2.22) BS01 TES ? GO:0003677 ... P39897 38326294
    46 8qrd:A (2.3) BS02 TES N/A GO:0004497 ... Q59819 N/A
    47 8qrd:B (2.3) BS02 TES N/A GO:0004497 ... Q59819 N/A
    48 8qrd:C (2.3) BS02 TES N/A GO:0004497 ... Q59819 N/A
    49 8qrd:D (2.3) BS02 TES N/A GO:0004497 ... Q59819 N/A
    50 8qrd:E (2.3) BS02 TES N/A GO:0004497 ... Q59819 N/A
    51 8qrd:F (2.3) BS02 TES N/A GO:0004497 ... Q59819 N/A
    52 8rtw:A (1.99) BS01 TES N/A N/A N/A 39206623
    53 8rtw:B (1.99) BS01 TES N/A N/A N/A 39206623
    54 8rtw:C (1.99) BS01 TES N/A N/A N/A 39206623
    55 8rtw:D (1.99) BS01 TES N/A N/A N/A 39206623
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218