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BioLiP
Download all results in tab-seperated text for 11 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 4hwk:A (2.4) BS02 SFY 1.1.1.153 GO:0004033 ... P35270 23704574 MOAD: ic50=82nM
    2 4hwk:B (2.4) BS02 SFY 1.1.1.153 GO:0004033 ... P35270 23704574 MOAD: ic50=82nM
    3 4hwk:C (2.4) BS02 SFY 1.1.1.153 GO:0004033 ... P35270 23704574 MOAD: ic50=82nM
    4 4hwk:D (2.4) BS02 SFY 1.1.1.153 GO:0004033 ... P35270 23704574 MOAD: ic50=82nM
    5 5r9p:A (1.72) BS01 SFY 2.7.11.24 GO:0000077 ... P47811 32543856
    6 5rf8:A (1.44) BS01 SFY 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0008233 ... P0DTD1 33028810
    7 5rzb:A (1.59) BS01 SFY ? GO:0005856 ... Q9Y2J2 N/A
    8 6mwf:A (1.75) BS02 SFY 4.6.1.12 GO:0008299 ... Q3JRA0 N/A
    9 6mwf:C (1.75) BS02 SFY 4.6.1.12 GO:0008299 ... Q3JRA0 N/A
    10 7b8d:A (1.62) BS01 SFY 3.1.1.98 GO:0016787 ... Q6P988 35731924
    11 7h6l:C (1.33) BS01 SFY 2.1.1.-
    2.7.7.-
    2.7.7.19
    2.7.7.48
    3.1.3.84
    3.4.22.-
    3.6.1.15
    3.6.1.74
    3.6.4.13    		 N/A Q8JUX6 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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