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BioLiP
Download all results in tab-seperated text for 13 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 4u5j:A (2.26) BS01 RXT 2.7.10.2 GO:0004672 ... P00523 25197973 MOAD: ic50=2.92uM
    PDBbind: -logKd/Ki=5.53, IC50=2.93uM
    2 4u5j:B (2.26) BS01 RXT 2.7.10.2 GO:0004672 ... P00523 25197973 MOAD: ic50=2.92uM
    3 6vgl:A (1.9) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    4 6vgl:B (1.9) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    5 6vgl:C (1.9) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    6 6vgl:D (1.9) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    7 6vnk:A (2.0) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    8 6vnk:B (2.0) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    9 6vnk:C (2.0) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    10 6vnk:D (2.0) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 33570945 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    11 6wtn:A (1.83) BS01 RXT 2.7.10.2 GO:0004672 ... O60674 34110416 BindingDB: IC50=2.8nM, EC50=12nM, Kd=0.036000nM, Ki=0.100000nM
    12 7f3g:A (2.1) BS01 RXT 2.7.11.1 GO:0004672 ... O15075 34445192 BindingDB: Kd=68nM
    13 7f3g:B (2.1) BS01 RXT 2.7.11.1 GO:0004672 ... O15075 34445192 BindingDB: Kd=68nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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