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BioLiP
Download all results in tab-seperated text for 26 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1i6v:C (3.3) BS01 RFP 2.7.7.6 GO:0000428 ... Q9KWU7 11290327 PDBbind: -logKd/Ki=5.00, Ki=10uM
    2 1skx:A (2.8) BS01 RFP ? GO:0003677 ... O75469 15705662 BindingDB: EC50=3500nM
    3 1ynn:C (3.3) BS01 RFP 2.7.7.6 GO:0000428 ... Q9KWU7 15692574
    4 2hw2:A (1.45) BS03 RFP 2.4.2.30 GO:0016740 ... A0QRS5 18349144 MOAD: Ki=1.07mM
    PDBbind: -logKd/Ki=2.97, Ki=1.07mM
    5 3aob:C (3.35) BS01 RFP ? GO:0005515 ... P31224 22121023
    6 3aod:C (3.3) BS01 RFP ? GO:0005515 ... P31224 22121023
    7 4kmu:C (3.85) BS01 RFP 2.7.7.6 GO:0000345 ... P0A8V2 23679862 PDBbind: -logKd/Ki=7.92, IC50=12nM
    8 4kmu:H (3.85) BS01 RFP 2.7.7.6 GO:0000345 ... P0A8V2 23679862
    9 5hv1:A (3.103) BS02 RFP N/A GO:0005524 ... N/A 27001859 PDBbind: -logKd/Ki=4.10, Kd=79.4uM
    10 5kox:A (1.8) BS02 RFP 1.14.13.211 GO:0000166 ... Q5YTV5 27557658 MOAD: Kd=13uM
    11 5uac:C (3.8) BS01 RFP 2.7.7.6 GO:0000345 ... P0A8V2 28009073 PDBbind: -logKd/Ki=8.30, IC50<0.005uM
    12 5uah:C (4.1) BS01 RFP 2.7.7.6 GO:0000345 ... P0A8V2 28009073 PDBbind: -logKd/Ki=3.40, IC50=398uM
    13 5ual:C (3.887) BS01 RFP 2.7.7.6 GO:0000345 ... P0A8V2 28009073 PDBbind: -logKd/Ki=3.58, IC50=263uM
    14 5uh6:C (3.837) BS03 RFP 2.7.7.6 GO:0000428 ... P9WGY9 28392175
    15 5uhb:C (4.29) BS02 RFP 2.7.7.6 GO:0000428 ... P9WGY9 28392175
    16 5uhc:C (3.796) BS04 RFP 2.7.7.6 GO:0000428 ... P9WGY9 28392175
    17 5uhd:C (4.01) BS03 RFP 2.7.7.6 GO:0000428 ... P9WGY9 28392175
    18 5uhg:C (3.971) BS03 RFP 2.7.7.6 GO:0000428 ... P9WGY9 28392175
    19 6bed:A (2.75) BS01 RFP ? GO:0016020 ... P68440 30068608 PDBbind: -logKd/Ki=4.72, Kd=19uM
    20 6bed:C (2.75) BS01 RFP ? GO:0016020 ... P68440 30068608 PDBbind: -logKd/Ki=4.72, Kd=19uM
    21 6brd:A (3.32) BS02 RFP 1.14.13.211 GO:0000166 ... F2R776 29398560
    22 6brd:B (3.32) BS02 RFP 1.14.13.211 GO:0000166 ... F2R776 29398560
    23 6brd:C (3.32) BS02 RFP 1.14.13.211 GO:0000166 ... F2R776 29398560
    24 6ccv:C (3.05) BS02 RFP 2.7.7.6 GO:0000428 ... P60281 30297823
    25 7szj:C (3.11) BS02 RFP 2.7.7.6 GO:0000345 ... P0A8V2 35772744
    26 8k1n:C (3.0) BS01 RFP N/A GO:0005886 ... O05318 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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