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BioLiP
Download all results in tab-seperated text for 38 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1cbr:A (2.9) BS01 REA ? GO:0005501 ... P62965 7704533 PDBbind: -logKd/Ki=9.40, Kd=0.4nM
    BindingDB: Kd=>200nM
    2 1cbr:B (2.9) BS01 REA ? GO:0005501 ... P62965 7704533 PDBbind: -logKd/Ki=9.40, Kd=0.4nM
    BindingDB: Kd=>200nM
    3 1cbs:A (1.8) BS01 REA ? GO:0001972 ... P29373 7704533
    4 1fem:A (1.9) BS01 REA ? GO:0005501 ... P18902 7961949
    5 1g5y:B (2.0) BS01 REA ? GO:0003677 ... P19793 10970886
    6 1g5y:C (2.0) BS01 REA ? GO:0003677 ... P19793 10970886
    7 1gx9:A (2.34) BS01 REA ? GO:0005515 ... P02754 12054801
    8 1n4h:A (2.1) BS02 REA ? GO:0003677 ... P45446 12958591 MOAD: Kd=280nM
    PDBbind: -logKd/Ki=6.55, Ki=0.28uM
    9 1rlb:E (3.1) BS01 REA ? GO:0001654 ... P02753 7754382
    10 1rlb:F (3.1) BS01 REA ? GO:0001654 ... P02753 7754382
    11 2acl:A (2.8) BS01 REA ? GO:0003677 ... P19793 16107141
    12 2acl:C (2.8) BS01 REA ? GO:0003677 ... P19793 16107141
    13 2acl:E (2.8) BS01 REA ? GO:0003677 ... P19793 16107141
    14 2acl:G (2.8) BS01 REA ? GO:0003677 ... P19793 16107141
    15 2fr3:A (1.48) BS01 REA ? GO:0001972 ... P29373 16979656 MOAD: Kd=2nM
    PDBbind: -logKd/Ki=8.70, Kd=2.0nM
    16 2g78:A (1.7) BS01 REA ? GO:0001972 ... P29373 17447762 PDBbind: -logKd/Ki=6.92, Kd=120nM
    17 2lbd:A (2.06) BS01 REA ? GO:0003677 ... P13631 7501014
    18 2ve3:A (2.1) BS02 REA 1.14.-.- GO:0004497 ... Q59990 18512957 MOAD: Kd<1uM
    19 2ve3:B (2.1) BS02 REA 1.14.-.- GO:0004497 ... Q59990 18512957 MOAD: Kd<1uM
    20 3a9e:B (2.75) BS02 REA ? GO:0003677 ... P10276 21152046
    21 3cwk:A (1.6) BS01 REA ? GO:0001972 ... P29373 19018099 MOAD: Kd=250nM
    PDBbind: -logKd/Ki=6.60, Kd=250nM
    22 3fal:A (2.36) BS01 REA ? GO:0003677 ... P19793 18800767
    23 3fal:C (2.36) BS01 REA ? GO:0003677 ... P19793 18800767
    24 3fc6:A (2.063) BS01 REA ? GO:0003677 ... P19793 19167885
    25 3fc6:C (2.063) BS01 REA ? GO:0003677 ... P19793 19167885
    26 4dm8:A (2.3) BS02 REA ? GO:0003677 ... P10826 22355136
    27 4dm8:B (2.3) BS02 REA ? GO:0003677 ... P10826 22355136
    28 4tns:A (1.33) BS01 REA 5.2.1.8 GO:0003755 ... Q13526 N/A
    29 5fhz:A (2.9) BS02 REA 1.2.1.36 GO:0001758 ... P47895 27759097
    30 5fhz:B (2.9) BS02 REA 1.2.1.36 GO:0001758 ... P47895 27759097
    31 5fhz:C (2.9) BS02 REA 1.2.1.36 GO:0001758 ... P47895 27759097
    32 5fhz:D (2.9) BS02 REA 1.2.1.36 GO:0001758 ... P47895 27759097
    33 5uan:B (3.508) BS06 REA ? GO:0003677 ... P10826 29021580
    34 6eu9:B (2.69) BS01 REA ? GO:0000978 ... A0A384E144 29492455
    35 6eu9:D (2.69) BS01 REA ? GO:0000978 ... A0A384E144 29492455
    36 7y42:A (3.45) BS01 REA ? GO:0016020 ... P0DTC2 35862773
    37 7y42:B (3.45) BS01 REA ? GO:0016020 ... P0DTC2 35862773
    38 7y42:D (3.45) BS01 REA ? GO:0016020 ... P0DTC2 35862773
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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