Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 92 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1e8w:A (2.5) BS01 QUE 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... O02697 11090628
    2 1gp6:A (1.75) BS01 QUE 1.14.20.4 GO:0007033 ... Q96323 11796114
    3 1h1i:A (1.75) BS02 QUE 1.13.11.24 GO:0008127 ... Q7SIC2 12486225
    4 1h1i:B (1.75) BS02 QUE 1.13.11.24 GO:0008127 ... Q7SIC2 12486225
    5 1h1i:C (1.75) BS02 QUE 1.13.11.24 GO:0008127 ... Q7SIC2 12486225
    6 1h1i:D (1.75) BS02 QUE 1.13.11.24 GO:0008127 ... Q7SIC2 12486225
    7 2c9z:A (2.1) BS02 QUE 2.4.1.115
    2.4.1.91    		 GO:0008194 ... P51094 16482224
    8 2hck:A (3.0) BS01 QUE 2.7.10.2 GO:0004672 ... P08631 9024658
    9 2hck:B (3.0) BS02 QUE 2.7.10.2 GO:0004672 ... P08631 9024658
    10 2jj2:G (2.4) BS01 QUE 3.6.1.34 GO:0005515 ... P05631 17698806
    11 2jj2:I (2.4) BS03 QUE 3.6.1.34 GO:0005515 ... P19483 17698806
    12 2jj2:M (2.4) BS02 QUE 7.1.2.2 GO:0005515 ... P00829 17698806
    13 2jj2:N (2.4) BS01 QUE 3.6.1.34 GO:0005515 ... P05631 17698806
    14 2o3p:A (2.24) BS01 QUE 2.7.11.1 GO:0004672 ... P11309 17218638 MOAD: ic50=1.1uM
    PDBbind: -logKd/Ki=5.96, IC50=1.1uM
    BindingDB: IC50=1100nM, Kd=25nM
    15 2uxh:A (2.4) BS01 QUE ? GO:0000976 ... Q9AIU0 17466326
    16 2uxh:B (2.4) BS01 QUE ? GO:0000976 ... Q9AIU0 17466326
    17 3bpt:A (1.5) BS01 QUE 3.1.2.4 GO:0003860 ... Q6NVY1 N/A
    18 3bxx:A (2.9) BS02 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    19 3bxx:B (2.9) BS02 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    20 3bxx:B (2.9) BS03 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    21 3bxx:C (2.9) BS02 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    22 3bxx:C (2.9) BS03 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    23 3bxx:D (2.9) BS02 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    24 3bxx:D (2.9) BS03 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    25 3bxx:F (2.9) BS02 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    26 3bxx:F (2.9) BS03 QUE 1.1.1.219
    1.1.1.234    		 GO:0009718 ... P51110 18645237
    27 3cf8:A (2.4) BS01 QUE 4.2.1.59 GO:0005737 ... Q5G940 18780820 MOAD: Ki=12.7uM
    PDBbind: -logKd/Ki=4.90, Ki=12.7uM
    28 3cf8:B (2.4) BS01 QUE 4.2.1.59 GO:0005737 ... Q5G940 18780820 PDBbind: -logKd/Ki=4.90, Ki=12.7uM
    29 3cf8:C (2.4) BS01 QUE 4.2.1.59 GO:0005737 ... Q5G940 18780820 MOAD: Ki=12.7uM
    30 3lj0:A (3.2) BS03 QUE 2.7.11.1
    3.1.26.-    		 GO:0004521 ... P32361 20417606
    31 3lj0:A (3.2) BS04 QUE 2.7.11.1
    3.1.26.-    		 GO:0004521 ... P32361 20417606
    32 3lj0:B (3.2) BS03 QUE 2.7.11.1
    3.1.26.-    		 GO:0004521 ... P32361 20417606
    33 3lm5:A (2.29) BS01 QUE 2.7.11.1 GO:0004672 ... O94768 33215924
    34 3nvy:C (2.0) BS01 QUE 1.17.1.4
    1.17.3.2    		 GO:0005506 ... P80457 25060641 BindingDB: Ki=1200nM, IC50=31900nM
    35 3nvy:L (2.0) BS01 QUE 1.17.1.4
    1.17.3.2    		 GO:0005506 ... P80457 25060641 BindingDB: Ki=1200nM, IC50=31900nM
    36 4dfu:A (1.98) BS02 QUE ? GO:0000166 ... O68183 22195561 MOAD: Ki=25.1uM
    PDBbind: -logKd/Ki=4.60, Ki=25.1uM
    37 4dfu:A (1.98) BS03 QUE ? GO:0000166 ... O68183 22195561 MOAD: Ki=25.1uM
    PDBbind: -logKd/Ki=4.60, Ki=25.1uM
    38 4dfu:B (1.98) BS01 QUE ? GO:0000166 ... O68183 22195561 MOAD: Ki=25.1uM
    39 4dfu:B (1.98) BS03 QUE ? GO:0000166 ... O68183 22195561 MOAD: Ki=25.1uM
    40 4lmu:A (2.38) BS01 QUE 2.7.11.1 GO:0004672 ... P11309 24531473 PDBbind: -logKd/Ki=7.26, IC50=55nM
    BindingDB: IC50=1100nM, Kd=25nM
    41 4mra:A (2.34) BS01 QUE 2.4.1.1 GO:0000166 ... P00489 24556570 MOAD: ic50=33.5uM
    PDBbind: -logKd/Ki=4.47, IC50=33.5uM
    42 4wnj:B (1.398) BS01 QUE ? GO:0005179 ... P02766 26249340
    43 5a4v:A (2.38) BS01 QUE 2.5.1.18 GO:0000325 ... P46422 28174680
    44 5a4v:B (2.38) BS01 QUE 2.5.1.18 GO:0000325 ... P46422 28174680
    45 5a4v:C (2.38) BS01 QUE 2.5.1.18 GO:0000325 ... P46422 28174680
    46 5a4v:D (2.38) BS01 QUE 2.5.1.18 GO:0000325 ... P46422 28174680
    47 5a4v:E (2.38) BS01 QUE 2.5.1.18 GO:0000325 ... P46422 28174680
    48 5a4v:F (2.38) BS01 QUE 2.5.1.18 GO:0000325 ... P46422 28174680
    49 5auw:A (1.5) BS01 QUE 2.7.11.1 GO:0004672 ... P53355 26322379 MOAD: ic50=8.9uM
    PDBbind: -logKd/Ki=5.05, IC50=8.9uM
    BindingDB: IC50=8900nM
    50 5fli:A (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    51 5fli:B (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    52 5fli:C (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    53 5fli:D (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    54 5fli:E (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    55 5fli:F (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    56 5fli:G (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    57 5fli:H (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    58 5fli:J (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    59 5fli:K (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    60 5fli:L (2.15) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    61 5flj:A (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    62 5flj:B (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    63 5flj:C (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    64 5flj:D (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    65 5flj:E (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    66 5flj:F (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    67 5flj:G (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    68 5flj:H (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    69 5flj:I (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    70 5flj:J (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    71 5flj:K (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    72 5flj:L (1.818) BS02 QUE 1.13.11.24 N/A A2VA43 26846734
    73 5xg4:U (3.0) BS01 QUE 3.4.21.73 GO:0004252 ... P00749 28644504 PDBbind: -logKd/Ki=5.15, IC50=7uM
    BindingDB: IC50=20000nM
    74 6aws:A (2.35) BS01 QUE ? GO:0004864 ... Q6VT83 N/A
    75 6aws:A (2.35) BS02 QUE ? GO:0004864 ... Q6VT83 N/A
    76 6aws:A (2.35) BS03 QUE ? GO:0004864 ... Q6VT83 N/A
    77 6aws:C (2.35) BS01 QUE ? GO:0004864 ... Q6VT83 N/A
    78 6aws:C (2.35) BS02 QUE ? GO:0004864 ... Q6VT83 N/A
    79 6aws:C (2.35) BS03 QUE ? GO:0004864 ... Q6VT83 N/A
    80 6b1d:A (2.51) BS01 QUE ? GO:0004864 ... Q6VT83 N/A
    81 6b1d:C (2.51) BS01 QUE ? GO:0004864 ... Q6VT83 N/A
    82 6ijd:A (3.206) BS01 QUE 2.4.1.- GO:0005576 ... Q9LNE6 30893500
    83 6ijd:B (3.206) BS01 QUE 2.4.1.- GO:0005576 ... Q9LNE6 30893500
    84 6m89:A (1.85) BS01 QUE 2.7.1.140
    2.7.1.151
    2.7.1.153    		 GO:0016301 ... Q8NFU5 30624931 MOAD: ic50=2.3uM
    PDBbind: -logKd/Ki=5.64, IC50=2.3uM
    BindingDB: IC50=2300nM
    85 6qcd:A (1.84) BS03 QUE 2.3.1.-
    2.3.1.286
    2.4.2.-    		 GO:0070403 ... Q8N6T7 31844103
    86 6qcd:B (1.84) BS03 QUE 2.3.1.-
    2.3.1.286
    2.4.2.-    		 GO:0070403 ... Q8N6T7 31844103
    87 6qcn:B (2.23) BS01 QUE 2.3.1.-
    2.3.1.286    		 GO:0017136 ... Q8IXJ6 31844103
    88 6tta:A (-1.00) BS03 QUE 3.5.2.6 N/A E9NWK5 32426604
    89 7vum:A (2.319) BS01 QUE ? GO:0003697 ... P40947 35054774
    90 7vum:C (2.319) BS01 QUE ? GO:0003697 ... P40947 35054774
    91 8gqt:D (2.09) BS01 QUE 2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0008233 ... P0DTD1 N/A
    92 8sfw:A (2.75) BS02 QUE ? GO:0000166 ... T1KUK4 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218