Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 24 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1eli:A (2.0) BS02 PYC 1.5.3.1 GO:0005737 ... P40859 10913292 MOAD: Kd=1.37mM
    2 1eli:B (2.0) BS02 PYC 1.5.3.1 GO:0005737 ... P40859 10913292 MOAD: Kd=1.37mM
    3 1eli:B (2.0) BS03 PYC 1.5.3.1 GO:0005737 ... P40859 10913292 MOAD: Kd=1.37mM
    4 1l9d:A (1.95) BS02 PYC 1.5.3.1 GO:0005737 ... P40859 12146941
    5 1l9d:B (1.95) BS02 PYC 1.5.3.1 GO:0005737 ... P40859 12146941
    6 1w61:A (2.1) BS01 PYC 5.1.1.4 GO:0005576 ... Q4DA80 16446443
    7 1w61:B (2.1) BS01 PYC 5.1.1.4 GO:0005576 ... Q4DA80 16446443
    8 1w62:A (2.5) BS01 PYC 5.1.1.4 GO:0005576 ... Q4DA80 16446443 MOAD: Ka=4600000M^-1
    9 2cwh:A (1.7) BS02 PYC 1.4.1.17
    1.5.1.21    		 GO:0000166 ... Q4U331 16192274
    10 2cwh:B (1.7) BS03 PYC 1.4.1.17
    1.5.1.21    		 GO:0000166 ... Q4U331 16192274
    11 3ad8:B (2.2) BS03 PYC 1.5.3.24 GO:0000166 ... Q50LF2 20675294 MOAD: Kd=0.69mM
    PDBbind: -logKd/Ki=3.16, Kd=0.69mM
    12 4j9w:A (1.6) BS01 PYC 5.1.1.8 GO:0016853 ... Q4KGU2 N/A
    13 4j9w:B (1.6) BS01 PYC 5.1.1.8 GO:0016853 ... Q4KGU2 N/A
    14 4k7g:B (2.0) BS01 PYC 4.2.1.77 GO:0016829 ... B9K4G4 N/A
    15 4k7g:D (2.0) BS01 PYC 4.2.1.77 GO:0016829 ... B9K4G4 N/A
    16 4q60:A (2.1) BS01 PYC 5.1.1.8 GO:0003824 ... B3D6W2 N/A
    17 4q60:B (2.1) BS01 PYC 5.1.1.8 GO:0003824 ... B3D6W2 N/A
    18 5c7v:A (2.504) BS02 PYC 2.3.3.9 GO:0000287 ... P9WK17 27738104
    19 7pb3:AAA (2.841) BS01 PYC 5.1.1.4 GO:0016853 ... E3PTZ4 N/A
    20 7pb3:BBB (2.841) BS01 PYC 5.1.1.4 GO:0016853 ... E3PTZ4 N/A
    21 8a3f:AAA (3.15) BS01 PYC 5.1.1.4 GO:0016853 ... E3PTZ4 N/A
    22 8a3f:BBB (3.15) BS01 PYC 5.1.1.4 GO:0016853 ... E3PTZ4 N/A
    23 8a4r:AAA (3.59) BS01 PYC 5.1.1.4 GO:0016853 ... E3PTZ4 N/A
    24 8a4r:BBB (3.59) BS01 PYC 5.1.1.4 GO:0016853 ... E3PTZ4 N/A
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218