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BioLiP
Download all results in tab-seperated text for 16 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1c88:A (1.8) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 10744717 MOAD: Ki=5.1uM
    PDBbind: -logKd/Ki=5.29, Ki=5.1uM
    BindingDB: IC50=500000nM, Ki=11500nM
    2 5k9w:A (2.01) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 MOAD: Kd=26uM
    PDBbind: -logKd/Ki=4.59, Kd=26uM
    BindingDB: IC50=500000nM, Ki=11500nM
    3 5ka1:A (1.84) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 MOAD: Kd=33uM
    PDBbind: -logKd/Ki=4.48, Kd=33uM
    BindingDB: IC50=500000nM, Ki=11500nM
    4 5ka3:A (2.141) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 MOAD: Kd=26uM
    PDBbind: -logKd/Ki=4.59, Kd=26uM
    BindingDB: IC50=500000nM, Ki=11500nM
    5 5ka7:A (2.061) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 MOAD: Kd=45uM
    PDBbind: -logKd/Ki=4.35, Kd=45uM
    BindingDB: IC50=500000nM, Ki=11500nM
    6 5ka9:A (2.07) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 MOAD: Kd=39uM
    PDBbind: -logKd/Ki=4.41, Kd=39uM
    BindingDB: IC50=500000nM, Ki=11500nM
    7 5kab:A (1.968) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 PDBbind: -logKd/Ki=4.68, Kd=21uM
    BindingDB: IC50=500000nM, Ki=11500nM
    8 5kad:A (1.9) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 MOAD: Kd=37uM
    PDBbind: -logKd/Ki=4.43, Kd=37uM
    BindingDB: IC50=500000nM, Ki=11500nM
    9 5kad:B (1.9) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 28212750 MOAD: Kd=37uM
    BindingDB: IC50=500000nM, Ki=11500nM
    10 7mm1:A (1.85) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 35916223 BindingDB: IC50=500000nM, Ki=11500nM
    11 7mn7:A (1.95) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 35921420
    12 7mna:A (1.47) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 35921420
    13 7mnb:A (2.2) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 35921420
    14 7mnd:A (2.29) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 35921420
    15 7mnf:A (1.7) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 35921420
    16 7mow:A (1.8) BS01 OTA 3.1.3.48 GO:0004725 ... P18031 35921420
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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