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BioLiP
Download all results in tab-seperated text for 24 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2vw2:A (1.7) BS01 NHE 3.2.1.18 GO:0004308 ... Q54727 18835278 PDBbind: -logKd/Ki=3.30, Ki=0.5mM
    2 2vw2:A (1.7) BS02 NHE 3.2.1.18 GO:0004308 ... Q54727 18835278 PDBbind: -logKd/Ki=3.30, Ki=0.5mM
    3 3kjr:A (1.95) BS02 NHE 1.5.1.3
    2.1.1.45    		 GO:0000166 ... A7ASX7 20000709
    4 4q11:A (1.95) BS01 NHE ? GO:0005737 ... B4EUU9 25056110
    5 4q11:B (1.95) BS01 NHE ? GO:0005737 ... B4EUU9 25056110
    6 4ygr:A (1.703) BS01 NHE ? GO:0016311 ... B6YTD6 25858319
    7 4ygr:A (1.703) BS02 NHE ? GO:0016311 ... B6YTD6 25858319
    8 5tsp:A (1.24) BS01 NHE 3.2.1.18 GO:0004308 ... A0A0H2YQR1 28315686
    9 5tsp:B (1.24) BS01 NHE 3.2.1.18 GO:0004308 ... A0A0H2YQR1 28315686
    10 5whk:A (2.5) BS01 NHE ? N/A P55899 28878017
    11 5whk:A (2.5) BS02 NHE ? N/A P55899 28878017
    12 6cex:A (2.57) BS01 NHE ? GO:0019031 ... Q91MA7 29610325 PDBbind: -logKd/Ki=1.70, Kd>20mM
    13 6cex:B (2.57) BS01 NHE ? GO:0019031 ... P03436 29610325
    14 6cex:C (2.57) BS01 NHE ? GO:0019031 ... Q91MA7 29610325
    15 6cex:D (2.57) BS01 NHE ? GO:0019031 ... P03436 29610325
    16 6cex:E (2.57) BS01 NHE ? GO:0019031 ... Q91MA7 29610325
    17 6cf5:A (2.04) BS01 NHE ? GO:0019031 ... Q6DQ33 29610325 PDBbind: -logKd/Ki=1.70, Kd>20mM
    18 6cf5:C (2.04) BS01 NHE ? GO:0019031 ... Q6DQ33 29610325
    19 6cf5:E (2.04) BS01 NHE ? GO:0019031 ... Q6DQ33 29610325
    20 6jxn:A (1.97) BS02 NHE 1.6.5.-
    1.7.1.17    		 GO:0000166 ... G9QLG5 32861785
    21 6jxn:B (1.97) BS02 NHE 1.6.5.-
    1.7.1.17    		 GO:0000166 ... G9QLG5 32861785
    22 6jxn:B (1.97) BS03 NHE 1.6.5.-
    1.7.1.17    		 GO:0000166 ... G9QLG5 32861785
    23 6jxn:C (1.97) BS01 NHE 1.6.5.-
    1.7.1.17    		 GO:0000166 ... G9QLG5 32861785
    24 6jxn:D (1.97) BS02 NHE 1.6.5.-
    1.7.1.17    		 GO:0000166 ... G9QLG5 32861785
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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