Home Research COVID-19 Services Publications People Teaching Job Opening News Forum --> -->
Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 10 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

    • Sort results by
    << < 1 > >>
    Go to page

    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 1u2o:A (2.1) BS01 NEC ? GO:0005524 ... P41148 12970348
    2 1u2o:B (2.1) BS01 NEC ? GO:0005524 ... P41148 12970348
    3 1ysz:A (2.65) BS01 NEC ? GO:0005524 ... P41148 15951571
    4 2ydv:A (2.6) BS01 NEC ? GO:0001609 ... P29274 21593763 PDBbind: -logKd/Ki=7.86, Ki=13.8nM
    BindingDB: Ki=16nM, IC50=3.7nM, EC50=251nM
    5 5g53:A (3.4) BS01 NEC ? GO:0001609 ... P29274 27462812 PDBbind: -logKd/Ki=6.37, Ki=430nM
    BindingDB: Ki=16nM, IC50=3.7nM, EC50=251nM
    6 5g53:B (3.4) BS01 NEC ? GO:0001609 ... P29274 27462812 BindingDB: Ki=16nM, IC50=3.7nM, EC50=251nM
    7 6b99:A (1.60238) BS01 NEC 3.6.4.10 GO:0005524 ... P07900 N/A
    8 6d28:A (1.75) BS01 NEC ? GO:0005524 ... P41148 12970348 MOAD: Kd=200nM
    PDBbind: -logKd/Ki=6.70, Kd=200nM
    9 6gdg:A (4.11) BS01 NEC ? GO:0001609 ... P0AA25
    P29274    		 29726815 PDBbind: -logKd/Ki=8.74, Ki=1.8nM
    10 7xy7:R (3.26) BS01 NEC ? GO:0001609 ... P0ABE7
    P29275    		 36563137
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

    • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218